Gene 8817 (Tetrahymena)

8817

Species: Tetrahymena
Alias: 15.m00528, 554, PreTt08817, 8817, TTHERM_00191670, 3697.m00239
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-B3

Sequence

Name Sequence Type Origin Length Description Download
8817.AA Protein None 482 None Fasta, JSON
8817.kin_dom Protein Kinase Domain None 68 None Fasta, JSON
8817.NA RNA None 1449 None Fasta, JSON

Protein domain

Protein domains of 8817.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8817.AA Ciliate-B3 98-165 69 9.4e-42 145.03 In-house 1-69 (69) Show / Hide 
Range on Protein: 98-165
Range on HMM: 1-69/69
Sequence Identity: 69% (48 aa)

FALYHFTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSN-GLKDILIDFGHCQSKKQNEKSEAVCGTLTY
|||.||.|||..||.||..|.||||||||||||.||.. ..|.|.|||||||.|.||.|||..||||||
FALKHFHQVVEKIKILHEKNICHCDIKVDNILVNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY
Kinase 8817.AA Ciliate-E1 6-190 21 9e-13 38.3 In-house 1-202 (202) Show / Hide 
Range on Protein: 6-190
Range on HMM: 1-202/202
Sequence Identity: 21% (44 aa)

IACGGQSVCYRV------ETQKGNIYFLKEFF-TKTEYNHEKKIYQ-HLNEITKEI-DLSILKMIDHDDH-KCQILFPFINFQLSLICS------KVKQN
|. |..|. ..       . |.  . .. .|. .. ... |.| |.  .. . ||.  . |...|..|.   | |.| . . .|    .      ...| 
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

NTRGMKWIFA--LYHFTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSNGLKDILIDFGHCQ--SKKQNEKSEAVCGTLTYNPLEL---NEGIAKQQIKEY
..   .. |   .. . | .  .  ||..|..|.||| .|||...|.|...    ||| ..   ..||. .   . |  | | |    .|  . .. ...
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC---DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKI

SPYMLDLF
. |..|..
N-YKSDIY
Kinase 8817.AA Ciliate-C8 105-196 22 8.9e-12 38.78 In-house 127-238 (238) Show / Hide 
Range on Protein: 105-196
Range on HMM: 127-238/238
Sequence Identity: 22% (25 aa)

QVVNTIKKLHSLNLCHCDIKVDNILVEQQ-SNGLKDILID------FGHCQSKKQNEK---------SEAV-----CGTLTYNPLELNEGIAKQQIKEYS
|.   .  ||  |  | ||| .|.||  . ....   | |      ||     ..|.          ....     ||...| . |. ... ..| . .|
QMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFS

PYMLDLFQLGMLL
    |....| .|
KK-SDSYSVGLVL
Kinase 8817.AA C8 105-196 30 4.7e-10 31.2 In-house 131-226 (226) Show / Hide 
Range on Protein: 105-196
Range on HMM: 131-226/226
Sequence Identity: 30% (30 aa)

QVVNTIKKLHSLNLCHCDIKVDNILVEQQSNGL-KDILIDFGHCQSKKQNEK---SEAV--CGTLTYNPLELNEGIAKQQIKEYSPYMLDLFQLGMLL
|..  .  .|. |  | ||| .|.||  . | . .  | |||     ..|..   |  .  |||..|   |  ..  ..| |.|.    |||..|..|
QMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKK-QDNQYKQYR-IQSDLFSVGLVL
Kinase 8817.AA Ciliate-E8 105-147 41 6.4e-10 27.2 In-house 97-138 (138) Show / Hide 
Range on Protein: 105-147
Range on HMM: 97-138/138
Sequence Identity: 41% (18 aa)

QVVNTIKKLHSLNLCHCDIKVDNILVEQQSNGLKDILIDFGHC
|. . .  ||..|  |||.| .|||| |    .|  .||||  
QIMDAFCYLHNNNIIHCDFKLNNILV-QRNDDTKIKIIDFGFS
Kinase 8817.AA Ciliate-E2-Unclassified 99-165 25 8.1e-10 30.26 In-house 140-228 (352) Show / Hide 
Range on Protein: 99-165
Range on HMM: 140-228/352
Sequence Identity: 25% (23 aa)

AL-----YHFTQVVNTIKKLHSLN-LCHCDIKVDNILVEQQSNGLKDILIDFGHCQSKKQN----------------EKSEAVCGTLTY
|.     . | |... ...||. |  .| ||| .|||. .. . ..  .|||| .   .||                ...  .|||. |
AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNY
Kinase 8817.AA CAMK 103-165 19 1.9e-09 25.83 In-house 185-285 (425) Show / Hide 
Range on Protein: 103-165
Range on HMM: 185-285/425
Sequence Identity: 19% (20 aa)

FTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSNG--------------LKDILIDFGHCQSKKQ------------------------NEKSEAVCGTLT
| |..  .. .||.| .|.|.| .|||. . ...               .  .||||  . ...                        ..| . .|||. 
FRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPE

Y
|
Y
Kinase 8817.AA MARK 103-165 37 2.5e-09 26.85 In-house 110-171 (262) Show / Hide 
Range on Protein: 103-165
Range on HMM: 110-171/262
Sequence Identity: 37% (24 aa)

FTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSN-GLKDILIDFGHCQSKKQNEKSEAVCGTLTY
|.|.|  .. .|| | .|.||| .|||. .. |   |  .|||| .   . ..| .  |||. |
FRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIK--IIDFGFSICIPPGQKLNTFCGTPPY
Kinase 8817.AA S_TKc 4-361 12 1.8e-08 -52.85 SMART 5-231 (231) Show / Hide 
Range on Protein: 4-361
Range on HMM: 5-231/231
Sequence Identity: 12% (46 aa)

KQIACGGQSVCYRVETQK-GNIYFLKEFFTKTEYNHEKKIYQHLNEITKEIDLSILKMIDHDDHKCQILFPFINFQLSLICSKVKQNNTRG----MKWIF
..|  |. ...|..   | | |. .|.         | .| ..     .   .  |. . .| ..  . . ...  |    .  |.....|    .    
RKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

ALYHFTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSNGLKDILIDFGHCQSKKQNEKSEAVCGTLTYNPLELNEGIAKQQIKEYSPYMLDLFQLGMLLLT
| . . |... .. .||.. .|.|.| .|||. .        ..||| .           .|||. | . |.           |..   |   .| .|  
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---------GYGKCKCDWWSCGCILYE

LIV-YFPISEKNKKLISLKKKNKFLELITLKYKETYNTNLQMIPEVYNLIWDLLTGEIEDVASILDHEVYDLQEVINMLKCLPQTGNTKASQMEEEEEFN
... | | .     .  . || .                                                                             
MLCGYPPFP----QMQMMFKKIG-----------------------------------------------------------------------------

FDNIRFYKKDDGNRCNGTVSIEKEFQEMLQESTKYEELKEQIIQFCDKNPRQ-IKESELQK-------RSFL
                                   .|.|. | . ..|.|.. .   |. .         ..
----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8817.AA CAMK-Unique 103-165 22 6.7e-08 21.94 In-house 163-241 (363) Show / Hide 
Range on Protein: 103-165
Range on HMM: 163-241/363
Sequence Identity: 22% (18 aa)

FTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSN-------------GLKDILIDFGHCQSKKQNEKSE---AVCGTLTY
.....  .. .||..  | |.| .||.|    .              ..  |.||| |  . .|....   ..|||. |
MQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCY
Kinase 8817.AA Ciliate-E2 94-221 18 8.6e-08 22.8 In-house 142-305 (365) Show / Hide 
Range on Protein: 94-221
Range on HMM: 142-305/365
Sequence Identity: 18% (33 aa)

MKWIFALYHFTQVVN---------------TIKKLHSLN-LCHCDIKVDNILVEQQSNGLKDILIDFGHCQSKKQNEKSEA-------------------
...  ..| ..|...                .. ||| |  .| ||| .|||.          .|||| ..  ..... .                    
FTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPG

-------------VCGTLTYNPLELNEGIA--KQQIKEYSPYMLDLFQLGMLLLTLIVY-FPISEKNKKLISLKKKNKF
             .|||. | . |  .|    .|| ...  |. |.. ||..|  ..   .|        .  .|..|.
YMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKI
Kinase 8817.AA Pkinase 103-165 26 5.5e-07 25.77 Pfam 114-177 (293) Show / Hide 
Range on Protein: 103-165
Range on HMM: 114-177/293
Sequence Identity: 26% (18 aa)

FTQVVNTIKKLHSLNLCHCDIKVDNILVEQQSNGL----KDILIDFGHCQS--KKQNEKSEAVCGTLTY
..|..  .. .|| . .|.|.| .|||.  . . .    |  ..||| .       |.    .|||. |
MYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVK--ICDFGLAKQFDY-NNS-MTTFCGTPWY
Kinase 8817.AA Ciliate-E2-Unclassified 4-71 16 0.088438 1.98 In-house 5-83 (352) Show / Hide 
Range on Protein: 4-71
Range on HMM: 5-83/352
Sequence Identity: 16% (13 aa)

KQIACGGQSVCYRVETQKGN-IYFLKEFFTKTEYNHEKKIYQHLNEITKEIDLSILKMIDHDD------------HKCQIL
|||  ||... |...  | . .|..|.   . .|.  .. ... ... ... . ..|. .|..            |.. ..
KQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFI