Gene 8815 (Tetrahymena)
8815
Group:
Other
Family:
Ciliate-B3
Sequence
Protein domains of 8815.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 8815.AA | Ciliate-B3 | 105-172 | 72 | 4.6e-37 | 128.49 | In-house | 1-69 (69) | Show / Hide |
Range on Protein: 105-172 Range on HMM: 1-69/69 Sequence Identity: 72% (51 aa) LALKLFHLVVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQ--ELNRKSTMNCGTTEF .|||.||.|||||||||.||||||||||.||| ||.||||||||||||||..| . | ||.| ||| . FALKHFHQVVEKIKILHEKNICHCDIKVDNIL-VNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY |
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Kinase | 8815.AA | MLCK | 120-175 | 30 | 6.3e-13 | 29.88 | In-house | 113-168 (257) | Show / Hide |
Range on Protein: 120-175 Range on HMM: 113-168/257 Sequence Identity: 30% (18 aa) LHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRK---STMNCGTTEFNPP .|..||.| |.| .||.... .. .. |||||. ...... . ..|| ||..| MHWQNIVHLDLKPENIMCQT---RTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAP |
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Kinase | 8815.AA | Ciliate-E2 | 117-213 | 24 | 7.4e-13 | 40.46 | In-house | 173-291 (365) | Show / Hide |
Range on Protein: 117-213 Range on HMM: 173-291/365 Sequence Identity: 24% (32 aa) IKILHSKN-ICHCDIKVHNILLVNVQDKENYKVIIIDFG---QYQELNRKSTM-------------------------------NCGTTEFNPPKLIEDA .. ||||| |.| ||| |||. . ||||| .|.. | . |. ||| .. .| .. LEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGK DRLKKFGKQIEEYSPQELDVYQLGMLLFRMLT . . | ... . |.. ||..|..||. KYDNQ---QKQKGYDYKCDIWSLGVILYEMLF |
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Kinase | 8815.AA | CAMK | 120-175 | 24 | 2.8e-12 | 35.13 | In-house | 195-289 (425) | Show / Hide |
Range on Protein: 120-175 Range on HMM: 195-289/425 Sequence Identity: 24% (23 aa) LHSKNICHCDIKVHNILLVNVQDKEN------------YKVIIIDFGQYQELNR--------------------------KSTMNCGTTEFNP-P .||.||.|.|.| ||||.. | .. ... ||||| ..... | . ||| |. . | CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP |
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Kinase | 8815.AA | MSK | 117-213 | 27 | 4.3e-10 | 30.29 | In-house | 114-205 (277) | Show / Hide |
Range on Protein: 117-213 Range on HMM: 114-205/277 Sequence Identity: 27% (28 aa) IKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRK---STMN-CGTTEFNPPKLIEDADRLKKFGKQIEEYSPQELDVYQLGMLLFRML .. .|.| | | |.| |||. . .| | .| .|||| .... . |.| .. .| ...... .| ..|... |.. || .|. || VDHMHQKGIIHRDLKPENILFDDEED--NGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGY------AQDGGYDEA-CDWWSLGVILYTML T | T |
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S_TKc | 8815.AA | S_TKc | 9-370 | 10 | 1.6e-09 | -37.47 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-370 Range on HMM: 1-231/231 Sequence Identity: 10% (42 aa) YQLNDVKFEGGQSTGLIYTDQKTKQVYFKKIFDEEIDYVREKAFYKEILIKIDPKDRSSFLELLHFNDNNKE--LIFPFINS---KLVDKCTKQKGI--- |.. .. .|. .. .. ||.... || . . ...|| | . |. . .. .. ... ... | | |... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --KSRYLALKLFHLVVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRKSTMNCGTTEFNPPKLIEDADRLKKFGKQIEEYSPQE . | .... ... .. .||..|.|.|.| |||| . . |.||| .| | ||| .. .| .. |.. . FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL----TTFCGTPWYMAPEVL--------------GYGKCK LDVYQLGMLLFRMLT--QLYLSISLKKVAQNKMKKDFFKEQIKKLYKSEYKTELILDDDIFDLGKIKPDEEDLQFEDMVKFKEDQNSSRSKGESIQNEIK |.. .| .|. ||. .. .... .. . CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------------------------------------------------------------- QAHKKYCDLMRESENFDQFNEWQGAFFKLQPRKIDRKKLYGGSLLTEMSTEDLLNVLLSILAENNN-----QIFS-------QNIF ...... . .| . . ... | -------------------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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Kinase | 8815.AA | Ciliate-E2-Unclassified | 117-216 | 25 | 2.6e-09 | 28.47 | In-house | 156-268 (352) | Show / Hide |
Range on Protein: 117-216 Range on HMM: 156-268/352 Sequence Identity: 25% (32 aa) IKILHSKN-ICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELN------------------RKSTMNCGTTEFN----PPKLIED-ADRLKKFGKQIE .. ||.|| |.| ||| |||. | . ||.. ||||| ... ... .||| .. .| ... .|. LEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA----- EYSPQELDVYQLGMLLFRMLTQLY . |.. ||..|. ||.. | ----YKCDIWSLGVILYEMLFGYY |
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Kinase | 8815.AA | C8 | 113-208 | 23 | 2.1e-08 | 25.43 | In-house | 132-226 (226) | Show / Hide |
Range on Protein: 113-208 Range on HMM: 132-226/226 Sequence Identity: 23% (24 aa) VVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRKS----TMN---CGTTEFNPPKLIED-ADRLKKFGKQIEEYSPQELDVYQL ... . .|.||| | ||| ||.| | . ...... . ||| . . . ||| .. | ... ...|.. .| |.... MIDGVNYIHCKNIMHRDIKPHNFL-VCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQ--------SDLFSV GMLL |..| GLVL |
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Kinase | 8815.AA | Ciliate-E8 | 117-156 | 45 | 2.7e-08 | 22.03 | In-house | 102-138 (138) | Show / Hide |
Range on Protein: 117-156 Range on HMM: 102-138/138 Sequence Identity: 45% (18 aa) IKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQY . .||. || |||.| |||.. | |. ||||| FCYLHNNNIIHCDFKLNNILVQRNDD---TKIKIIDFGFS |
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Kinase | 8815.AA | CMGC | 117-154 | 27 | 3.9e-07 | 18.49 | In-house | 195-249 (513) | Show / Hide |
Range on Protein: 117-154 Range on HMM: 195-249/513 Sequence Identity: 27% (15 aa) IKILHSKN--ICHCDIKVHNILLVNVQDK---------------ENYKVIIIDFG .| .||.. |.|.|.| |||. . . .|... |.||| LKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG |
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Kinase | 8815.AA | DAPK | 120-154 | 48 | 4.3e-07 | 16.4 | In-house | 119-152 (264) | Show / Hide |
Range on Protein: 120-154 Range on HMM: 119-152/264 Sequence Identity: 48% (17 aa) LHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFG .|||.||| |.| || | . | .. ||||| MHSKHICHFDLKPENIMLLD-RNVPNPRIKIIDFG |
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Kinase | 8815.AA | Pkinase | 120-213 | 28 | 2e-06 | 23.75 | Pfam | 124-207 (293) | Show / Hide |
Range on Protein: 120-213 Range on HMM: 124-207/293 Sequence Identity: 28% (28 aa) LHSKNICHCDIKVHNILLV-NVQDKENYKVIIIDFGQ---Y-QELNRKSTMNCGTTEFNPPKLIEDADRLKKFGKQIEEYSPQELDVYQLGMLLFRMLT .||..|.|.|.| |||.. | . .. .| |.||| . |. | ||| .. .| .| .| ... |.. .| .|. ||. CHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----------GGQYYGPKVDMWSCGCILYEMLC |