Gene 12433 (Tetrahymena)
12433
Group:
Other
Family:
Ciliate-A9
Sequence
Protein domains of 12433.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 12433.AA | Ciliate-A9 | 22-378 | 62 | 0.0 | 914.03 | In-house | 1-392 (392) | Show / Hide |
Range on Protein: 22-378 Range on HMM: 1-392/392 Sequence Identity: 62% (245 aa) FKPIKVIGQGAFGKVIQAIDNS--TNQEVAIKVINKKKMGEDCIEKVKQEARILEKLNHPNVVEFK---------------------KVCETDTKILIAM |.|||.||.||||.|||..|.. ..||.|.|||.|.||..||||...|||.||....|||.|.|| |.||.|..|.|.| FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQEAKILQQHDHPNIVKFKNIKNINTQKETKQLNYIFQISKFCESDQNIHIVM ELVRGGSLSQLMKERKSKNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIF |....|.|.|||||||..|.||.|.|.|||||.||....|.|.|||.||||||||||||||||||||||||||||||||||||||||||||||||||||| EYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIF ILTENILINDVNDFTSIKIADFGLSS---------AFSLWTTNGLTEQCGTLLYMAPEFFASRVYSKKVKHAVSMKSRKRLIYLFLQLIILFLNSLKSQN ||||||||.|.||.|..||||||||. .|..||......|||||.|||||||....||..|.|||||||||||||||||||||||||||||| ILTENILIGDKNDLTQVKIADFGLSKSFVKSQRVQYFTQWTYHSMYQQCGTLIYMAPEFFINKQYSQPVDHAVSMKSRKRLIYLFLQLIILFLNSLKSQN QFILYRQFKQQIDIWSCGITMHNLLDFGNHPFYEP--KADDADTFKQKLS-NPKWKIPAHFSNLAKNLLSKLSLINPTERYSAIQALQHPFI |||||||||||.|.|||||.|..||..|.|||..| |.||.|.||.|.. ||.|......||.|||...|...|||..||.|.|.|.||.| QFILYRQFKQQVDMWSCGIIMYMLLCMGKHPFWCPYEKNDDEDYFKMKIQCNPQWEFWDNCSNNAKNFIQKMTNINPSNRYNAFQCLKHPWI |
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Kinase | 12433.AA | S_TKc | 22-378 | 23 | 7.4e-63 | 216.06 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 22-378 Range on HMM: 1-231/231 Sequence Identity: 23% (85 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGEDCIEKVKQEARILEKLNHPNVVEFKKVCETDTKILIAMELVRG--GSLSQLMKERKS--KN .. ...||.|||||| ......|...||||.|. |....| .||.| .|||.| .. |... ... . ||.. | |.| ...|.|.. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR DWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIFILTENILINDVNDFTSIKI .| | .. .|. | ..| |.| ..|.||||||. | ..... ||| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPE---N----ILLDE------------------------------------------------HIKI ADFGLSSAFSLWTTNGLTEQCGTLLYMAPEFFASRVYSKKVKHAVSMKSRKRLIYLFLQLIILFLNSLKSQNQFILYRQFKQ-QIDIWSCGITMHNLLDF .||||. . | .|||. ||||| . .. .|.||||... .| CDFGLARQL--------TTFCGTPWYMAPEVL----------------------------------------------GYGKCKCDWWSCGCILYEMLC- GNHPFYEPKADDADTFKQKLSNPKWKIPAHFSNLAKNLLSKLSLINPTERYSAIQALQ-------HPFI | ||. ... .||. . | ||....|. .|..|..| .||| ||.. GYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 12433.AA | MARK | 22-258 | 29 | 9e-50 | 160.96 | In-house | 1-187 (262) | Show / Hide |
Range on Protein: 22-258 Range on HMM: 1-187/262 Sequence Identity: 29% (73 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGE-DCIEKVKQEARILEKLNHPNVVEFKKVCE--TDTK-ILIAMELVRGGSLSQLMKER--KS .| .|.||.|...|| |.. |...||||...|.|. . ...|. |..|. ||.|||.... .| | | .. | . ||.. ||.| . .|.. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR KNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIFILTENILINDVN--DFT .|.| .| . | .. | | |||||||.|| ||||| . . . ----LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKP--------------------------------------------------ENILIDENGNHN-- SIKIADFGLSSAFSLWTTNGLTEQCGTLLYMAPEFFASRVYS-KKV |||.|||.| . . |.. |||. ||||| | .. | .|| -IKIIDFGFSICIPPGQK--LNTFCGTPPYMAPEIFLKKPYDGPKV |
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Kinase | 12433.AA | CAMK | 27-152 | 23 | 2.6e-45 | 143.5 | In-house | 1-208 (425) | Show / Hide |
Range on Protein: 27-152 Range on HMM: 1-208/425 Sequence Identity: 23% (50 aa) VIGQGAFGKVIQAIDNSTN------------QEVAIKVINKKKMGED--------------------------CIEKVKQEARILEK-------LNHPNV ..|.|.|||| .|. .|. |.||||.|.|||. .. ..|..| .|. | |.|||. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VEFKKVCE------------TDTK--------ILIAM---ELVRGG----SLSQLMKERKS----------KNDW--FKEKEVSQIMKSIMLGLVYIHGK . . | | | .| . . | |.. || | . .|... .. |.|.|...... | .. |.| . IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH NIVHRDLKPD |||||||||. NIVHRDLKPE |
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Kinase | 12433.AA | CAMKL | 22-152 | 30 | 2.8e-45 | 142.37 | In-house | 1-156 (297) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-156/297 Sequence Identity: 30% (47 aa) FKPIKVIGQGAFGKVIQAID-NSTNQEVAIKVINKKKMGEDCIEK-------------VKQEARILEKLN---HPNVVEFKKVCETDTK------ILIAM .. .|..|.|.|||| |.. |...||||.|.|||. .|.. | ...|..|...|| |||.. . | ||... | . | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELVRGGS--LSQLMKERKSKNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDLKPD |.. ||. | . .... ... ..|.| .. . |. .. |.| ..|||||.||. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPE |
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Kinase | 12433.AA | CAMK1 | 22-151 | 34 | 4.5e-42 | 120.06 | In-house | 1-136 (276) | Show / Hide |
Range on Protein: 22-151 Range on HMM: 1-136/276 Sequence Identity: 34% (48 aa) FKPIKVIGQGAFGKVIQAIDNST---NQEVAIKVIN-KKKMGEDCI---EKVKQEARILEK---LNHPNVVEFKKVCETDTKILIAMELVRGGS-LSQLM .. .|.|| |||..| .... .| ....|||.|. || | .. |....| |. | ..|||.. |. . |.|... . |||| || . . . YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV KERKSKNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDLKP . . ||. . ||| | . |.| |.|||||||| EKG-----NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKP |
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Kinase | 12433.AA | Pkinase | 22-152 | 30 | 2.9e-41 | 147.0 | Pfam | 1-137 (293) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-137/293 Sequence Identity: 30% (43 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGEDCIEKVKQ--EARILEKLNHPNVVEFKKVCETDTKILIAMELVRGG----SLSQLMKERKS .. ...||.|.||.| .... .|...||.|.|.|.. ... . |..|. .|||||.|... ..|....| . ||...|| .|. ... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W KNDWF--KEKEVSQIMKSIMLGLVYIHGKNIVHRDLKPD .. .| |.|. .|. | || |.| ..|.||||||. RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPE |
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Kinase | 12433.AA | Ciliate-E2a | 22-152 | 36 | 1.3e-39 | 114.28 | In-house | 1-131 (275) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-131/275 Sequence Identity: 36% (49 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGEDC--IEKVKQEARILEKLNHPNVVEFKKVCETDTKILIAMELVRGGSLSQLMKERKSKNDW .| ||.||.|.||.| | |... |.|...| || .. |....| |. .|.|||. . | |... . . ||.. ||.| . .|. |. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKR---- FKEK--EVSQIMKSIM-LGLVYIHGKNIVHRDLKPD |.|. |...||. . || |.| .||.||||||. FFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPE |
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Kinase | 12433.AA | STE | 22-152 | 24 | 2.8e-37 | 129.21 | In-house | 1-181 (359) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-181/359 Sequence Identity: 24% (44 aa) FKPIKVIGQGAFGKVIQAIDN------STNQE---------VAIKVINKKKMG---------------EDCIEKVKQEARILEKLN--HPNVVEFKKVCE .. |..||.||||.| .|... .|... .|||..|... .. ......| .|. |.| |||.|.. .. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF TD-------TKILIAMELVRGGSLSQLMKERKSKND----------WFKEKEVSQIMKSIMLG-LVYIHGKNIVHRDLKPD . ... |.||.. ||||....|....... .|.|.... | ..| | | |.| ..|.|||.||. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPA |
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Kinase | 12433.AA | Ciliate-E2 | 22-152 | 29 | 1.7e-36 | 122.77 | In-house | 1-190 (365) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-190/365 Sequence Identity: 29% (56 aa) FKPIKVIGQGAFGKVIQAIDNSTNQ------------------EVAIKVINKKKMGEDCIEKVKQEARIL----------------EKLNHPNVVEFKKV .| ||.||||.||.| .. . .... .|.|| ...| | .. || .||| .|. |.|||||..... . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC CE--TDTKILIAMELVRGGSLSQLMKERKSKND-------WFKEKEVSQIMKSIML---------------GLVYIHGKN-IVHRDLKPD . .|..| . ||.. ||.| ...|..| | . |.|||...||| | .| |.| || |.|||.||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE |
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Kinase | 12433.AA | CAMK-Unique | 22-152 | 20 | 7e-31 | 99.03 | In-house | 1-186 (363) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-186/363 Sequence Identity: 20% (39 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMG-EDCIE-----------------KVKQEARILEKLNHPNVVEFKKV----CETDT------- | ...||.|.||.|. ..| .| . |.|...|.. | . .. | | |..|. ...||| ... . .... YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI --------KILIAMELVRGGSLSQLMKER-KSK---------------NDWFKE--KEVSQIMKSIMLGLVYIHGKNIVHRDLKPD .. | ||.. || |.... .. . . . | | ....|| .. . | | ..|||||||.. IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLE |
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Kinase | 12433.AA | Ciliate-E2-Unclassified | 22-152 | 27 | 5.6e-30 | 101.18 | In-house | 1-173 (352) | Show / Hide |
Range on Protein: 22-152 Range on HMM: 1-173/352 Sequence Identity: 27% (48 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGEDCIEKVK----QEARILEKLN-------------------HPNVVEFKKVCETDTKILIAM .| ||.||||.|||| ........| |.| ..|... ... . | .|. ...... ||..| . . ... .| | | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM ELVRGGSLSQLMKERKS----KND---------WFKEKEVS-----QIMKSIMLGLVYIHGKN-IVHRDLKPD |...||.|.| .|.||. .|| | |.... .... | .|| |.| || |.|||.||. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPE |
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Kinase | 12433.AA | Pkinase_Tyr | 22-149 | 30 | 1.2e-24 | 84.1 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 22-149 Range on HMM: 1-137/270 Sequence Identity: 30% (42 aa) FKPIKVIGQGAFGKVIQAIDN----STNQEVAIKVINKKKMGED-CIEKVKQEARILEKL-NHPNVVEFKKVCE-TDTK--ILIAMELVRGGSLSQLMKE . .|..|.||||.| ... . .|...||.|... . | |. |.|. .||.|. .| .|||.| . || . |.| ||.. .|.| .. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK RKSKNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDL ... .. .. |. |. | |. | . ||..|||| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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Kinase | 12433.AA | CAMK | 299-378 | 21 | 1.7e-17 | 52.27 | In-house | 313-425 (425) | Show / Hide |
Range on Protein: 299-378 Range on HMM: 313-425/425 Sequence Identity: 21% (24 aa) QQIDIWSCGITMHNLLDFGNHPFYEP-----------KADDADTFKQKLSNPKWKIPAHFSN-----------------------LAKNLLSKLSLINPT ...|.||||. . .| | |||.. ...| ..|.. .. . .| .||. .|.|..|. .|. PKCDMWSCGVILYIML-CGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPE ERYSAIQALQHPFI .|... |.|.||.. KRMTIEQCLNHPWM |
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Kinase | 12433.AA | Ciliate-E2 | 300-378 | 22 | 1.3e-14 | 46.52 | In-house | 276-365 (365) | Show / Hide |
Range on Protein: 300-378 Range on HMM: 276-365/365 Sequence Identity: 22% (23 aa) QIDIWSCGITMHNLLDFGNHPFYEPKADDADTFKQKLSNPKWKIP------------------AHFSNLAKNLLSK----LSLINPTERYS-AIQALQHP ..||||.|.... .| ||..|| |. . |...| . |. .|.|..| . .| .|.. . |.|.|| KCDIWSLGVILYEML-FGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP FI .. WF |
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Kinase | 12433.AA | CAMK-Unique | 299-378 | 26 | 4.2e-14 | 42.76 | In-house | 268-363 (363) | Show / Hide |
Range on Protein: 299-378 Range on HMM: 268-363/363 Sequence Identity: 26% (26 aa) QQI----DIWSCGITMHNLLDFGNHPFYEPKADD------ADTFKQ-------KLSNPKWKIPAHFSNLAKNLLSKLSLINPTERYSAIQALQHPFI || ||||.| .|. .| .|..||... |. . .|. ......| .| |. ||... .. . | | || ..|.|..| QQCSPASDIWSLGVIMYYML-CGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 12433.AA | Ciliate-E2-Unclassified | 300-378 | 25 | 8.4e-14 | 44.28 | In-house | 250-352 (352) | Show / Hide |
Range on Protein: 300-378 Range on HMM: 250-352/352 Sequence Identity: 25% (27 aa) QIDIWSCGITMHNLLDFGNHPFYEPK------------------ADDADTFKQKLSNPK-WK--IPAHFSNLAKNLLS----KLSLINPTERYSAIQALQ ..||||.|. .. .| ||..||| .. . .......|| .. || | |. ||.... |. || .|... |.|. KCDIWSLGVILYEML-FGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN HPFI ||.. HPWF |
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Kinase | 12433.AA | CAMKL | 299-378 | 23 | 2.4e-12 | 35.54 | In-house | 215-297 (297) | Show / Hide |
Range on Protein: 299-378 Range on HMM: 215-297/297 Sequence Identity: 23% (20 aa) QQIDIWSCGITMHNLLDFGNHPFYEP-----KADDADTFKQKLSNPKWKIPAHFSN-LAKNLLSKLSLINPTERYSAIQALQHPFI ...||||||... ... .|. || .. ..|. ... | ..| ... ...|..|. ||..|... | ..||. PKVDIWSCGVILYAMV-CGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 12433.AA | Ciliate-E2a | 347-378 | 37 | 4.2e-12 | 31.94 | In-house | 244-275 (275) | Show / Hide |
Range on Protein: 347-378 Range on HMM: 244-275/275 Sequence Identity: 37% (12 aa) FSNLAKNLLSKLSLINPTERYSAIQALQHPFI .|. .|.|..|. .| .|..|.|||.||. CSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | 12433.AA | CAMKL | 202-254 | 36 | 5.5e-12 | 34.38 | In-house | 156-212 (297) | Show / Hide |
Range on Protein: 202-254 Range on HMM: 156-212/297 Sequence Identity: 36% (21 aa) ENILINDVNDFTSIKIADFGLSSAFS---LWTTNGLTEQCGTLLYMAPEFFAS--RVY ||||. . .. |||.|||.| . .. . |...||.. ||||| |.. . | ENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPY |
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Kinase | 12433.AA | CAMK1 | 202-258 | 36 | 1e-11 | 30.24 | In-house | 137-197 (276) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 137-197/276 Sequence Identity: 36% (23 aa) ENILINDVNDFTSIK--IADFGLSSAFSLWTTN-GLTEQCGTLLYMAPEFFAS---RVYSKKV ||.| | . || ||||||| |. . .. .|||. |.||| .. |.|.. ENLLYYDKDEDSKIKRSIADFGLSKIFD--HDENLMKTACGTPGYVAPEVLECKKDKPYDKAC |
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Kinase | 12433.AA | TyrKc | 22-281 | 15 | 1.1e-11 | -33.84 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 22-281 Range on HMM: 1-280/280 Sequence Identity: 15% (56 aa) FKPIKVIGQGAFGKVIQAIDNSTNQEVAIKVINKKKMGEDCIEKVKQEARILEKL--NHPNVVEFKKVCETD-------TKILIAMELVRGGSLSQLMKE . .|..| ||||.| ... . ..||.|.... . .| .||||. || .|||.| . || .. ..| ||.. .|.| . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK RKSKNDWFKEKEVSQIMKSIMLGLVYIHGKNIVHRDL-------KPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIFILTENIL .. | .. |. ... | | |.| ||..|||| . .. HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------------------------------------------- INDVNDFTSIKIADFGLSSAF----------SLWTTNG--LTEQCGTLLYMAPEFFASR---------------------------------VYSKKVKH .||.||||| . . .. . . . |||| . . . . | . --------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE AVSMKSRKRLIYL------------------------------FLQLIILF | | . | ... .| YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 12433.AA | Pkinase | 202-258 | 42 | 1.5e-11 | 41.88 | Pfam | 137-193 (293) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 137-193/293 Sequence Identity: 42% (25 aa) ENILINDVNDF-TSIKIADFGLSSAFSLWTTNGLTEQCGTLLYMAPEFFA-SRVYSKKV |||||.. .. ...||.||||. |. . |..| |||. ||||| .. |..|| ENILIDNNGHIDACVKICDFGLAKQFD-Y-NNSMTTFCGTPWYMAPEVIRGGQYYGPKV |
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Kinase | 12433.AA | CAMK | 202-258 | 25 | 3.1e-11 | 31.74 | In-house | 208-315 (425) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 208-315/425 Sequence Identity: 25% (27 aa) ENILINDVNDFTS--------------IKIADFGLSSAFSL------------------WTTN----GLTEQCGTLLYMA-PEFFAS------------- ||||..| || .. |||.|||.. | ||| ....|||. ||| || . . ENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEE -RVYSKKV . |..|. KPYYGPKC |
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Kinase | 12433.AA | CAMK1 | 348-378 | 34 | 3.6e-11 | 28.65 | In-house | 245-276 (276) | Show / Hide |
Range on Protein: 348-378 Range on HMM: 245-276/276 Sequence Identity: 34% (11 aa) SNL-AKNLLSKLSLINPTERYSAIQALQHPFI |. ||...... .|..||.. |.|.||.| SDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | 12433.AA | Ciliate-E2 | 202-258 | 22 | 2.6e-10 | 31.56 | In-house | 190-277 (365) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 190-277/365 Sequence Identity: 22% (22 aa) ENILINDVNDFTSIKIADFGLSSAFS-------------LWTTNG------------------LTEQCGTLLYMAPEFFASRV---------YSKKV ||||. |||.||||| .. ... . .|||. ||||| . . |..|. ENILF--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKC |
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Kinase | 12433.AA | CAMK-Unique | 202-258 | 22 | 8.2e-10 | 28.37 | In-house | 186-270 (363) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 186-270/363 Sequence Identity: 22% (19 aa) ENILINDV-ND------------FTSIKIADFGLSSAFSLWTTNG-LTEQCGTLLYMAP--------------EFFASRVYSKKV |||... .| .. ||..||||. .. . . . |||..|||| | . . |. .. ENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQC |
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Kinase | 12433.AA | STE | 302-378 | 21 | 2e-09 | 29.59 | In-house | 250-359 (359) | Show / Hide |
Range on Protein: 302-378 Range on HMM: 250-359/359 Sequence Identity: 21% (24 aa) DIWSCGITMHNLLDFGNHPF---YEPKADDADTFKQKLSN----------PKWKIP-------------------AHFSNLAKNLLSKLSLINPTERYSA |||| |.|. ... |..|. . ..| . .|... .. | ..| ..| |. ..| ..| .| .| DIWSLGCTIIEMAT-GKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA IQALQ--HPFI | |. |||| SQLLKSEHPFI |
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Kinase | 12433.AA | Ciliate-E2a | 202-258 | 31 | 5.7e-09 | 22.58 | In-house | 131-197 (275) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 131-197/275 Sequence Identity: 31% (21 aa) ENILIN--DVNDF--TSIKIADFGLSSAFSLWTTNGLTEQCGTLLYMAPEFFASRV------YSKKV ||||.. . |. . |||.||||. .. . . .||| |.||| .... |..|. ENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC |
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Kinase | 12433.AA | MARK | 301-378 | 30 | 7.6e-09 | 25.22 | In-house | 187-262 (262) | Show / Hide |
Range on Protein: 301-378 Range on HMM: 187-262/262 Sequence Identity: 30% (24 aa) IDIWSCGITMHNLLDFGNHPFYEPKADD--ADTFKQKLSNPKWKIPAHFSNLAKNLLSKLSLINPTERYSAIQALQHPFI .||||.|. . .. |. || .|. . ..| ..| .|| | | ..||...| .|| || .. . ..||.. VDIWSLGVVLYFMV-CGYFPFD---GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 12433.AA | Pkinase | 301-378 | 19 | 8.3e-09 | 32.22 | Pfam | 193-293 (293) | Show / Hide |
Range on Protein: 301-378 Range on HMM: 193-293/293 Sequence Identity: 19% (20 aa) IDIWSCGITMHNLLDFGNHPFYEP----KADDADTFKQKLSNPKWKIPAHFS---------------------NLAKNLLSKLSLINPTERYSAIQALQH .|.||||.... .| .|. ||.. . .| . .. |... . . .| ..... .|..|..| |.||| VDMWSCGCILYEML-CGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH PFI |.. PWF |
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Kinase | 12433.AA | Ciliate-E2-Unclassified | 202-258 | 27 | 5.9e-08 | 23.71 | In-house | 173-251 (352) | Show / Hide |
Range on Protein: 202-258 Range on HMM: 173-251/352 Sequence Identity: 27% (22 aa) ENILINDVNDFTSIKIADFGLSS--------------AFSLWTTNGLTEQCGTLLYM----APEFFASRVYS----KKV ||||... . |||.|||.|. .. | . .. .|||. || ||| . . |. .|. ENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKC |
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Kinase | 12433.AA | STE | 203-247 | 23 | 7e-06 | 17.0 | In-house | 182-232 (359) | Show / Hide |
Range on Protein: 203-247 Range on HMM: 182-232/359 Sequence Identity: 23% (14 aa) NILINDVNDFTSIKIADFGLSSAFSL--------------WTTN-GLTEQCGTLLYMAPE |||. .|..|||... .. |. . .|| .|||| NILL--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE |
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Kinase | 12433.AA | Ciliate-E2a | 299-328 | 33 | 0.000293 | 8.47 | In-house | 195-223 (275) | Show / Hide |
Range on Protein: 299-328 Range on HMM: 195-223/275 Sequence Identity: 33% (10 aa) QQIDIWSCGITMHNLLDFGNHPFYEPKADD .. |.||||. .. || .| ||. .... TKCDMWSCGVIFYILL-CGKPPFKGKTYNE |
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Kinase | 12433.AA | Pkinase_Tyr | 203-223 | 38 | 0.403149 | 4.42 | Pfam | 141-158 (270) | Show / Hide |
Range on Protein: 203-223 Range on HMM: 141-158/270 Sequence Identity: 38% (8 aa) NILINDVNDFTSIKIADFGLS |.|... .. .||.||||. NCLVTE--NN-VVKICDFGLA |