Gene 18442 (Tetrahymena)

18442

Species: Tetrahymena
Alias: PreTt18442, TTHERM_00721340, 1002, 18442, 115.m00098
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A8

Sequence

Name Sequence Type Origin Length Description Download
18442.AA Protein None 593 None Fasta, JSON
18442.kin_dom Protein Kinase Domain None 139 None Fasta, JSON
18442.NA RNA None 1782 None Fasta, JSON

Protein domain

Protein domains of 18442.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 18442.AA Ciliate-A8 33-171 43 1.2e-85 290.86 In-house 1-151 (151) Show / Hide 
Range on Protein: 33-171
Range on HMM: 1-151/151
Sequence Identity: 43% (66 aa)

YKFERFIEENEFQYIVQAKSSEHQCLVAVKIFKYMNNLQCLEAY--EFEKSTLMKTKNERYALQLLDCLQNLEINMSGIVIEFCDC--------SLSAVS
||.....|...|.|.|||.|..|||.||.||.||||........  |.......|.|||.|.||...|.|..|.....||.|||||        .|....
YKYQKVLEKGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYKKKENLASIL

S--LNAFSFQQVLALTYQLIRGLQVLQQHGIFLKDVNSDNILYSWRKNKFI
.  ||.|.|.|..||||||...|.|.|..||...|....||||||.||.||
ENNLNKFTFEQIVALTYQLLKCLLVFQEKGIIHCDIKPQNILYSWSKNQFI
Kinase 18442.AA Ciliate-E1 39-173 26 1.1e-19 61.04 In-house 1-151 (202) Show / Hide 
Range on Protein: 39-173
Range on HMM: 1-151/202
Sequence Identity: 26% (41 aa)

IEENEFQYIVQAKSSEHQ-CLVAVKIFKYMNN-LQCLEAYEFEKST-LMKTKNERYALQLLDCLQNLEINMSGIVIEFCDCSLSAVSS------------
|... |  ...||. ... . ||.||...  |  |  . .| ..   .|| |.| | .|..|...  ..... |..|.|.|||    .            
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

--LNAFSFQQVLALTYQLIRGLQVLQQHGIFLKDVNSDNILYSWRKNKFIIA
   | |.|||......||| ||. |.|..|   | . .|||..   ......
QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC
Kinase 18442.AA S_TKc 33-352 13 2.4e-05 -98.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-352
Range on HMM: 1-231/231
Sequence Identity: 13% (47 aa)

YKFERFIEENEFQYIVQAKSSEHQCLVAVKIFKYMNNLQCLEAYEFEKSTLMKTKNERYALQLLDCLQNLEINMSGIVIEFCDC---SLSAVSSLNA---
|.. | | .  |    ...  . . .||.|| |        |  . | . |.|  .  .  .|.|. |.   .   .| |.||    .|  .   .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSFQQVLALTYQLIRGLQVLQQHGIFLKDVNSDNILYSWRKNKFI---IANVIRNFIIVGRKVFLQRSLQPLECNNLKTQFILEAIPELVNHQHIN
    |.  ..  ..||....|. . .|||   |.  .||| .    | .   .| ..                                           
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------------------------------------------

FVKDILANMVNPNQKEIFQPVQ-----LLHTLNNY-LVD---------ELCLQSLILPALSSENSVQTLKKIKIENFNDLNKIKEYQDISINLQNYNIFS
              . .          .|    ..  .|         |..      |     .  ...|||.                           
--------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------------------------

KEAKTIAEHIEKCSSVSKLTLNLLQVFMLSYHPFKRPIYNYRGN-------YIFA
                |.  .....  .| . | |||      .         . 
----------------SPEAKDFIR-KCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 18442.AA MOK 137-162 46 0.000781 7.33 In-house 107-132 (283) Show / Hide 
Range on Protein: 137-162
Range on HMM: 107-132/283
Sequence Identity: 46% (12 aa)

YQLIRGLQVLQQHGIFLKDVNSDNIL
|||.. |. .   ||| .||  .|||
YQLCKSLDHMHRNGIFHRDVKPENIL