Gene 13483 (Tetrahymena)

13483

Species: Tetrahymena
Alias: 38.m00318, 13483, TTHERM_00369610, PreTt13483, 1063
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A8

Sequence

Name Sequence Type Origin Length Description Download
13483.AA Protein None 661 None Fasta, JSON
13483.kin_dom Protein Kinase Domain None 123 None Fasta, JSON
13483.NA RNA None 1986 None Fasta, JSON

Protein domain

Protein domains of 13483.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13483.AA Ciliate-A8 2-133 48 2e-72 246.94 In-house 9-151 (151) Show / Hide 
Range on Protein: 2-133
Range on HMM: 9-151/151
Sequence Identity: 48% (69 aa)

NNRLSFVVQAQSLIDHNIVAIEILNN-DQMQELNDKKLEKCIQILEKFNDEKYFLQFKESIQDLEYGFVAIVTQVYEK--------NLAFILE--NNKLT
... | ||||.|......|||.|... .|....|||..|||||...|...|||.||. |.|||.|.||.||||.....        |||.|||  .||.|
KGDFSYVVQAYSINHQCQVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYKKKENLASILENNLNKFT

MKQIYALTYQLLRGVLLLEVQGIVIKDIQPQNILFSSSKNEFL
..||.|||||||...|... .||...||.|||||.|.||| |.
FEQIVALTYQLLKCLLVFQEKGIIHCDIKPQNILYSWSKNQFI
Kinase 13483.AA Ciliate-E1 2-135 20 2.1e-15 46.96 In-house 3-151 (202) Show / Hide 
Range on Protein: 2-135
Range on HMM: 3-151/202
Sequence Identity: 20% (31 aa)

NNRLSFVVQA--QSLIDHNIVAIEILNNDQMQELNDKKLEKCIQ-ILEKFNDEKYFLQFKESIQDLEYGFVAIVTQVYEKNLAFILE-------------
|.  |.|..|  |. .. ..  . |. .... . .. .. |... |.. |. |.| .|. . |.. .. . .|... ....|   |.             
NGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQ

-NNKLTMKQIYALTYQLLRGVLLLEVQGIVIKDIQPQNILFSSSKNEFLLQ
 .|..| .|. ....||. |.  |. ..| . || |||||.... ......
NQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC
Kinase 13483.AA CMGC 42-127 14 9.1e-09 23.97 In-house 72-219 (513) Show / Hide 
Range on Protein: 42-127
Range on HMM: 72-219/513
Sequence Identity: 14% (21 aa)

IQILEKFN----------------DEKYFLQFKESIQDLE---------------YGFVAIVTQVYEKNLAFILENNK----------LTMKQ-------
|.||...|                .... .. ...... .               .  . .|.   ...|. ...||.          |.  .       
IKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHR

-----IYALT------YQLLRGVL--LLEVQG--IVIKDIQPQNILFSS
     |  ..      ||.|||.    .  ..  |.  |. |.|||...
RPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINH
Kinase 13483.AA S_TKc 6-191 14 2e-06 -83.89 SMART 13-231 (231) Show / Hide 
Range on Protein: 6-191
Range on HMM: 13-231/231
Sequence Identity: 14% (35 aa)

SFVVQAQSLIDHNIVAIEILNNDQMQELNDKKLEKCIQILEKFNDEKYFLQFKESIQDLEYGFVAIVTQVYEK---NLAFILENNK-------LTMKQIY
. | ...   .. |||| |..         ..... ||||.|  . ..  ......||   ... .|.   .    .|  ......       ..  .. 
GKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

ALTYQLLRGVLLLEVQGIVIKDIQPQNILFSSSKN-----------------------------EF----------LLQALLQRKL---QGMEYLQLKSQ
 ..||.....  .  .||.  |. |.|||...  .                              .          .|  .| ..    | .. ...   
FYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-

NLLSVLPELLSHEGQEFITNILCRMVD--PDSNKISQ--------PMA
          |.|. .|| ..|..  .  |   .. |        |  
----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13483.AA Ciliate-F2 83-134 30 6e-06 17.76 In-house 86-137 (200) Show / Hide 
Range on Protein: 83-134
Range on HMM: 86-137/200
Sequence Identity: 30% (16 aa)

ILENNKLTMKQIYALTYQLLRGVLLLEVQGIVIKDIQPQNILFSSSKNEFLL
.|.  ||| .|.|  . |.. |.  ||  |..  ||   |..  . |. |..
QLQSCKLTDNQQYEEIQQFINGLAELENLGLIHGDIKIENMIYNRPKQRFMF
Kinase 13483.AA Ciliate-A1 86-124 32 0.000118 11.69 In-house 94-133 (301) Show / Hide 
Range on Protein: 86-124
Range on HMM: 94-133/301
Sequence Identity: 32% (13 aa)

NNK-LTMKQIYALTYQLLRGVLLLEVQGIVIKDIQPQNIL
.|. .   .|| . ||.  |.. .  . |. .|. |||||
QNDYMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNIL
Kinase 13483.AA CDK4 89-129 39 0.00026 10.46 In-house 107-147 (290) Show / Hide 
Range on Protein: 89-129
Range on HMM: 107-147/290
Sequence Identity: 39% (16 aa)

LTMKQIYALTYQLLRGVLLLEVQGIVIKDIQPQNILFSSSK
.  ..|  .. ||||||  |    |.  |  ||||| .|..
MPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDG
Kinase 13483.AA GSK 97-124 50 0.000732 7.02 In-house 121-148 (328) Show / Hide 
Range on Protein: 97-124
Range on HMM: 121-148/328
Sequence Identity: 50% (14 aa)

LTYQLLRGVLLLEVQGIVIKDIQPQNIL
..||..||   |.  ||.  || |||||
YMYQMFRGLAYLHSHGICHRDIKPQNIL