Gene 2641 (Tetrahymena)

2641

Species: Tetrahymena
Alias: 198.m00061, 2641, 3746.m00325, PreTt02641, 298, TTHERM_01016070
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
2641.AA Protein None 465 None Fasta, JSON
2641.NA RNA None 1398 None Fasta, JSON
2641.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of 2641.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 2641.AA CAMKK-Unclassified 93-379 39 2.9e-190 625.47 In-house 1-392 (392) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-392/392
Sequence Identity: 39% (156 aa)

YVFLDTLGRGSFGKVKLAVNRGDT---KQTKFAIKIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKKLRHANVVRLYEVIENPDNDKLYM--V
|.|||.||||||||||||..|..|   .|..||||.|||..||.|...|.|....||.|..|..|..||||||||.|.|...|||||..|||||.||  |
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKVFKKQKLKKKKFIYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPDNDKIYMGQV

IDYAQGGQLIEWDDDEEKFF--------------------FCNQSQNEAY-------------------------TEDYLRELFRGCIKGLSYLHNNG--
..|.|.||...||.......                    ||.|..|...                         .|.||...||.|.|||.|.||..  
MEYCQMGQIMSWDYWKQDYQPNDGEIEYFFQTQTEYKPDQFCCQYYNQNGKLHNRQNQKICLFSNQILEMKPYKMHEQYLKKYFRQCCKGLQYMHNFNQA

-------------------IIHRDIKPQNILLDSEGR-----PKLADFG--VSTVSETET-VSGNEGTYYFMPPEALSKENSKEGYNG------------
                   ||||||||||||.|.|..     .|.||||  |....|... ...|.|||.||.||..||||.|..||.            
CSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLR

-----------KKADVWSLGVTFFCFTFLEIPFQGSNLQEIFE-VIKQKDLAFPS--HRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
           ||||.|||||||.|......||...||||.|. .|.||...||.  |..||...|.|..||..|.|.|||...|....||.
KTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 2641.AA CAMKK 93-379 35 4.6e-178 570.21 In-house 1-396 (396) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-396/396
Sequence Identity: 35% (142 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKK----SFLKRKREYYRDSGGAMKY---------KDALDNVKKEIAIMKKLRHANVVRLYEVIENP
| .....|.|.|||||||.|..|| |...|||||.|     .||.|...|||....|..         ....|.|..|||||||..| |.|.|||||..|
YELMKEIGQGQFGKVKLAYNEYDT-QKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDP

DNDKLYMV-IDYAQGGQLIEWDDDEEKFF--------------------FCNQSQNEAY---------------TEDYLRELFRGCIKGLSYLH-NNG--
.|||.||| ..|...||...|........                    |...|.....               .|||... ||.||||| ||| ...  
QNDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKAC

-----------------IIHRDIKPQNILLDSEG---RPKLADFG--VSTVSETETVSG-----------NEGTYYFMPPEALSKENSKEGYNG------
                 ||||||||||||.|.||   ..|.||||  ... ....|.|.           ..||..||.||..||||.||.|||      
SYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFR

-----KKADVWSLGVTFFCFTFLEIPFQGSNLQEIFE---VIKQKDLAFPSH-----------RECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
     |.||.|.||||..||.|...||.. ||.....    ||.... ||..           .|.|..|| |...|.||.|||||...|. ..||.
FIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 2641.AA CAMK 98-379 24 8.5e-80 256.66 In-house 1-425 (425) Show / Hide 
Range on Protein: 98-379
Range on HMM: 1-425/425
Sequence Identity: 24% (107 aa)

TLGRGSFGKVKLAVNRGDT-KQ---------TKFAIKIFKKSFLKRK--------REYYRDSGGAMKYKD----ALDNVKKEIAIMKK-------LRHAN
||||||||||||.... .| |.         .|.|||| .|. || |            ..|.. . |..     ..||..||.||||       |.| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCY-KIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPN

VVRLYEVIENPD-----------------NDKLYMVI---DYAQGG----QLIEWDDDEEKFFFCNQSQNEA---------YTEDYLRELFRGCIKGLSY
...||||.|.|.                 ....|||    .|..||     | ..  . ... . .     .         .||.  | .||  . .. |
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF-----DQFDIVERGRFTEREARRYFRQICSAVHY

LHNNGIIHRDIKPQNILLDSE-----------------GRPKLADFGVSTVSET-------------------------ETVSGNEGTYYFMP-PEALSK
.|...|.|||.|| |||||.                  .  |..||| ... .                          .  .   || ..|. || |..
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

ENSK---------EGYNGKKADVWSLGVTFFCFTFLEIPFQGS-------------NLQEIFEVIKQKDLAFPSHR----------------------EC
.  .         . | |.|.|.||.||  .     . ||.|.             |..|.|| |.. .  ||..                       ..
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

SDGLKALFTKMIEKDPTKRISLTQLSEDPWL
|.  | |  || ..||.||....|  ..||.
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 2641.AA Pkinase 93-379 26 7.3e-78 269.79 Pfam 1-293 (293) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-293/293
Sequence Identity: 26% (87 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKRKREYY---RDSGGAMKYKDALDNVKKEIAIMKKLRHANVVRLYEVIENPDNDKLYMVID
|... ..|.||||.|......|. |  ..|.||.||.  | . ...   .                 ||.|||.|.| |.||||.. |.  .|..||| .
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRL----------------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVME

YAQGG----QLI----EWDDDEEKFFFCNQSQNEAY--TEDYLRELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSEGRP----KLADFGVST---VSET
|..||     |                   ... ..  .|. ..  ..  ..|| |.|..||||||.||.|||.|..| .    |..|||..        
YCEGGLYVMDLFDYIST-------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NN

ETVSGNEGTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFFCFTFLEIPFQGS------NLQEIFEVIKQKDLAFPSHRECS-----------------
.  ..  ||...|.|| .     .  | |.|.|.||.|...... . . ||.|.      . ..... |....| |..  .||                 
S-MTTFCGTPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--DGLKALFTKMIEKDPTKRISLTQLSEDPWL
  . .| . .....|||.||.. .|. ..||.
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 2641.AA S_TKc 93-379 28 2.9e-77 263.9 SMART 1-231 (231) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-231/231
Sequence Identity: 28% (84 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKKLRHANVVRLYEVIENPDNDKLYMVIDYAQ
| .|...|.|.||||.......   . ..|||| |                        .....||.|.|| .| |.|.||.|...   |.|||| .|. 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK------------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCD

G--GQLIEWDDDEEKFFFCNQSQNEA----YTEDYLRELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSEGRPKLADFGVSTVSETETVSGNEGTYYFMP
|  | |         | .  . . .     ..|   | ...  ...| |.|..||||||.||.|||||.  . |..|||....      .   || ..|.
GDLGDL---------FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMA

PEALSKENSKEGYNGKKADVWSLGVTFFCFTFLEIPFQGSNLQEIFEVIKQKDLAFPSHRECSDGLKALFTKMIEKDPTKRISLTQLSE-------DPWL
|| |       ||...|.|.||.|.... .   . ||.  ..|..|..|.            |. .| .  |. .|||.||..  .. .       .||.
PEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 2641.AA Ciliate-E2 93-379 24 6.2e-69 235.33 In-house 1-365 (365) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-365/365
Sequence Identity: 24% (95 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKRKR---EYYRDSGGAMKYK--DALDNVKKEIAIMKKLR----------------HANVVR
| |.  .|.|.||.|... .  . .| .|||||..   . .     |..  .  |||..  . . ..|.|| ||....                | |...
YKFIKKIGQGNFGSVYKCKV--WKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIK

LYEVIENPDNDKLYMVIDYAQGGQLIEWDDDEEKFFFCN--QSQNEAYTEDYLRELFRGCIK---------------GLSYLHNNG-IIHRDIKPQNILL
.||. .. |....|.| .|.||| | ..  .  |.....  . . . .||   .....  ..               .| |||... ||||||||.|||.
MYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

DSEGRPKLADFGVST------VSETETVSGNE----------------------------GTYYFMPPEALSKEN----SKEGYNGKKADVWSLGVTFFC
     .|..||| |.        .|.  ....                            ||...|.|| |....    .|. . ..|.|.|||||....
-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

FTFLEIPFQGSNLQEIFEVIKQKDLAFP----------------SHRECSDGLKALFTK----MIEKDPTKRIS-LTQLSEDPWL
. | . ||        .. |||... ||                |. ..|.  | |. |    |..||| |||.   |. . ||.
MLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 2641.AA ULK 93-379 26 1.4e-59 204.29 In-house 1-324 (324) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-324/324
Sequence Identity: 26% (90 aa)

YVFLDTLGRGSFG-KVKLAVNRGDT-KQTKFAI-KIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKKLR---HAN--VVRLYEVIENPDNDKL
|.  . || |||| ||  . |  .  .. ..|. .| ||.. | | |..    |    . .... |.|| |||||    | |  .|.||.. |..... .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQE----G----QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNI

YMVIDYAQGG---QLIE--------WDDDEEKFFFCNQSQNEAYTEDYLRELFRGCIKGLSYLHNNGIIHRDIKPQNILLDS------------EGRPKL
|.. .| .||   |.|.                       .   .|.  .. |.  . |. .||...||||||||||||.              .|. |.
YIIMEYCNGGDLEQYIKKNKKLPETE-------------EKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI

ADFGVSTVSETETVSGNE-----------GTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFFCFTFLEIPFQGSNLQEIFE--------------VIK
|||| . . . .. . .            || ..| |. |...  .. |. .|.|.||||. |.   . . ||...  .. ..               ||
ADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIK

QKDLAFP---SHRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
.. . ||   .   .|. .| |. .|...|...||| ... . ||.
NQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 2641.AA ULK 93-379 25 7.7e-59 201.79 In-house 1-329 (329) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-329/329
Sequence Identity: 25% (88 aa)

YVFLDTLGRGSFGKVKLAVNRGDT---KQTKFAIKIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKKLR--------HANVVRLYEVIENPDN
|.  . || ||||||  . |  .    ..  .. .| |... . . |..    |    . ... .|.|| |||||         | |.|.||.. |....
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQE----G----QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH

DKLYMVIDYAQGG---QLIE---------WDDDEEKFFFCNQSQNEAYTEDYLRELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSE------------G
. .|.. .| .||   |.|.                        .   .|.  .. |.  . |. .|| ..||||||||||||..              |
NNIYIIMEYCNGGDLEQYIKKNKKLPEDTE-------------EKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNG

RPKLADFGVSTVSETE-----TVSGNE------GTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFFCFTFLEIPFQGSNLQEIF-----EV-------
. |.|||| . . . .                 || ..| |. |...  .. |. .|.|.||||. |.   . . ||...  .. .     .        
VLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPW

---IKQKDLAFP---SHRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
   ||.. | ||   ..  .|. .| |. .|...|...||| ..| . ||.
PQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 2641.AA Ciliate-E2-Unclassified 93-379 25 1e-56 194.74 In-house 1-352 (352) Show / Hide 
Range on Protein: 93-379
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQT-----KFAIKIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKK--LRHANVVRLYEVIENPDNDKLY
| .. ..|.|.||||...... .  |      .  |.|.|.   ..|   .  .  .|. |   ....|   ||.   | | . ...... .  | ...|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

MVIDYAQGGQLIEWDDDEEK------FFFCNQSQNEAYTEDYLR-----ELFRGCIKGLSYLHNNG-IIHRDIKPQNILLDSEG---RPKLADFGVST--
.| .|..|| |...  . .|        | |. |..  ||   .      .|.  ..||.||| .. ||||||||.|||.|..|   ..|..||| |   
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

---------------VSETETVSGNEGTYYFM----PPEALSK-ENSKEGYNGKKADVWSLGVTFFCFTFLEIPFQGSNLQE----------------IF
               .   .  . . ||...|    .|| | . .....    .|.|.||||| .... | . ||.. |  .                ..
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

EVIKQKDLAFPSHRE------CSDGLKALFT----KMIEKDPTKRISLTQLSEDPWL
. ||||.. ||.. .       |.  | . .    ||..|.| |||.. |. . ||.
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 2641.AA Meta 219-379 39 2.5e-55 158.21 In-house 122-287 (287) Show / Hide 
Range on Protein: 219-379
Range on HMM: 122-287/287
Sequence Identity: 39% (66 aa)

EDYLRELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSEGRPKLADFGVSTVSETE--TVSG--NEGTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFF
||  .  ||  ..|| |||   |||||||| | ||...|  | ||||||   |    . ..    ||  || |||.| | ... | |. .|||..|||  
EDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACS-EEQNHFYCGRALDVWAMGVTLY

CFTFLEIPFQG--SNLQEIFEVIKQKDLAFPSHRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
|| |  .||.     .  ... ||.  . ||   | |. || ....| .|.|..|| . .. ..|| 
CFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase 2641.AA CAMKL 223-379 29 5.6e-42 131.66 In-house 130-297 (297) Show / Hide 
Range on Protein: 223-379
Range on HMM: 130-297/297
Sequence Identity: 29% (51 aa)

RELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSEG--RPKLADFGVSTVSE------TETVSGNEGTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFF
| .||  . ...|.|..||.|||||| |||||. |    |..||| |.  .       .. .   |.. .|.|| ...   .. |.|.|.|.||.||. .
RRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGN--NKPYDGPKVDIWSCGVILY

CFTFLEIPFQGS--------NLQEIFEVIKQKDLAFPSHRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
   . . || .         |  . .. |..    .| . . |  .. |  || ...|.||... |. ..||.
AMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 2641.AA MARK 223-379 30 4.9e-40 128.67 In-house 107-262 (262) Show / Hide 
Range on Protein: 223-379
Range on HMM: 107-262/262
Sequence Identity: 30% (50 aa)

RELFRGCIKGLSYLHNNGIIHRDIKPQNILLDSEG--RPKLADFGVSTVSETET-VSGNEGTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFFCFTFL
| .||  . ...|.|...|.||||||.|||.|..|    |..||| |.  ....  .   ||. .|.|| .    .|. |.|.|.|.|||||  .  .  
RRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIF----LKKPYDGPKVDIWSLGVVLYFMVCG

EIPFQGSN--LQEIFEVIKQKDLAFPSHRECSDGLKALFTKMIEKDPTKRISLTQLSEDPWL
  || |..  . |... |   .  .|.|   |.... |  ...  .| .|...... ..||.
YFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 2641.AA Meta 93-198 39 7.5e-38 106.86 In-house 1-113 (287) Show / Hide 
Range on Protein: 93-198
Range on HMM: 1-113/287
Sequence Identity: 39% (45 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKRKREYYRD---------SGGAMKYKDALDNVKKEIAIMKKLRHANVVRLYEVIENPDNDK
|.. . .|.||.|.|||| |  |  ..  |.||. |  |...    |           ||  . . .|| | .||||.||| | ||| |.||.  |  | 
YRLMEEIGKGSYGVVKLAYNEED--HHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDY

LYMVIDYAQGGQLIE
|||| .| ..|   |
LYMVFEYVEKGPVME
Kinase 2641.AA CAMKL 93-196 34 1.5e-36 114.07 In-house 1-110 (297) Show / Hide 
Range on Protein: 93-196
Range on HMM: 1-110/297
Sequence Identity: 34% (43 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLK-----------RKREYYRDSGGAMKYKDALDNVKKEIAIMKKLR---HANVVRLYEVIEN
| ...|||.|||||||||...  | ..| |||| .|. ..           .|.            .. . ....||.|||.|.   | |...||||||.
YRIGKTLGKGSFGKVKLATHIRTT-GEKVAIKIIDKKKIWNDPWMKKNKCGQKH------------ESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIET

PDN----DKLYMVIDYAQGGQ--L
|..    .|.|.|  |..||   |
PEHDIETKKIYLVMEYCSGGEMDL
Kinase 2641.AA MARK 93-199 36 1.2e-24 77.65 In-house 1-92 (262) Show / Hide 
Range on Protein: 93-199
Range on HMM: 1-92/262
Sequence Identity: 36% (40 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKR-KREYYRDSGGAMKYKDALDNVKKEIAIMKKLRHANVVRLYEVIENPDNDK-LYMVIDY
| .| |.| ||..|||||...  |. .|.|||| .|  | . .               .. ||. ||.||||| | |...|..||| ... . .|.. .|
YKMLKTIGHGSYAKVKLACHK-HTG-RKVAIKIYEKFKLNDPQ---------------WMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEY

AQGGQLIEW
| || | ..
ASGGELYDY
Kinase 2641.AA TyrKc 93-377 21 8.9e-16 32.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 93-377
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

YVFLDTLGRGSFGKVKLAVNRGDTKQTKFAIKIFKKSFLKRKREYYRDSGGAMKYKDALDNVKKEIAIMKKL--RHANVVRLYEVIENP-----DNDKLY
 .....||.| ||.| ... .     .. |.|  |..                     .    .|. ||.||  .| |.|||| |.  .       . |.
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM

MVIDYAQGGQLIEWDDDEEKFFFCNQSQNEAYTEDYLRELFRGCI---KGLSYLHNNGIIHRDIKPQNILLDSEGRPKLADFGVSTVSETE--------T
.|  |. .| | .   . ..                ...|   |.   .| .||| ...||||.   |.|...... | .||| |   . .        .
IVMEYMPHGDLKDYLRKHRPK-------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDY

VS-----GNE--GTYYFMPPEALSKENSKEGYNGKKADVWSLGVTFF-CFTFLEIPFQG-----SNLQEIFEVIKQKDLAFPSHR-------ECSDGLKA
 .     |      .  |.||..     ..|    | |||| ||. .  ||. . |  |      . ||..| .|| .   . .        .|.| .  
YRKKEHKGGKTMLPIRWMAPECI-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ

LFTKMIEKDPTKRISLTQLSEDP
. ..  . || .| . ... |. 
IMKQCWHEDPEDRPTFSEIHECF
Kinase 2641.AA Pkinase_Tyr 93-194 24 1.1e-09 33.45 Pfam 1-92 (270) Show / Hide 
Range on Protein: 93-194
Range on HMM: 1-92/270
Sequence Identity: 24% (28 aa)

YVFLDTLGRGSFGKVKLAVNR--GDTKQTKFAIKIFKKSFLKRKREYYRDSGGAMKYKDA---LDNVKKEIAIMKKL-RHANVVRLYEVIE-----NPDN
 .|. .||.|.||.|.... .  .| .... |.|. |                  .. .    ..   .|..|||.| .| |.|||| |.      |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----------------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---

DKLYMVIDYAQGG
 ..|.|  |...|
-QIYIVMEYMPHG
Kinase 2641.AA Pkinase_Tyr 231-267 37 2.8e-05 18.52 Pfam 122-158 (270) Show / Hide 
Range on Protein: 231-267
Range on HMM: 122-158/270
Sequence Identity: 37% (14 aa)

KGLSYLHNNGIIHRDIKPQNILLDSEGRPKLADFGVS
||..||.....||||.   |.|.....  | .||| .
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA