Gene 30307 (Tetrahymena)
30307
Group:
Other
Family:
Ciliate-A5
Sequence
Protein domains of 30307.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 30307.AA | Ciliate-A5 | 34-296 | 42 | 3.7e-140 | 471.94 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 34-296 Range on HMM: 1-275/275 Sequence Identity: 42% (116 aa) FGKCVLYQKKSKQNEYVICKKIQIGSEAKQKHIQQYFEQRMQIQHSNLLKFYGYSFNRQNSICSTNYSFNAYFEYHPISLLQENNNRQQNE--EIYQLNE |..|....|...|.||.|||..||..|..|||.|||||||||.||.|..|............||..|..|.|.|||...| ||...|.|.. ..|...| FYGCMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQE LWYMAKCLISLCDYLQQNDEVHPNIHPSSIFLTEAGQLKLVDSS-------VLNLSSPQQKQHHMSFENSQTHAQMQFEQRYIAPEEVIHQKNMNKYKLS |||...||||.|.|||||...|..|.|..|.||..||.||.|.. ..|.||..|.|||||.||.|....||..|.....|..|.....|.||.. LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSD VFQIGMTLLESALIQDCSYIYLEDDS-INQNS--LDFLINKVQEVYGDQFTTFLKKMLQLNPNNRPDIHEIYQQQ ||..||..||.....||...|..... ..||. ...||......|..||..|.|.|||...|.|||.|.|||.. VFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | 30307.AA | Ciliate-E4 | 46-173 | 28 | 9e-13 | 39.27 | In-house | 23-150 (150) | Show / Hide |
Range on Protein: 46-173 Range on HMM: 23-150/150 Sequence Identity: 28% (36 aa) QNEYVICKKIQIGSEAKQKHIQQYFEQRMQIQHSNLLKFYGYSFNRQNSICSTNYSFNAYFEYHPISLLQENNNRQQNEEIYQLNELWYMAKCLISLCDY | . .. | . .| | . || | .| .| |. . |.| ||. | .|| | |. ...| |.| .| |.|. | QKQIIVMKIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYY LQQNDEVHPNIHPSSIFLTEAGQLKLVD ||| | .. || ||... |..| LQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| S_TKc | 30307.AA | S_TKc | 23-298 | 14 | 3.1e-08 | -56.19 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 23-298 Range on HMM: 1-231/231 Sequence Identity: 14% (44 aa) VIVEGQEVQGIFGKCVLYQKKSKQNEYVICKKIQIGSEAKQKHIQ---QYFEQRMQIQHSNLLKFYGYSFNRQNSICSTNYSFNAYFEYHPI---SLLQE . . .| |||. . ..|. ...| .|.| .||. | .. .| |. |.|.. . .. .|| . .|.. YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-------EHIRREIQILKK----HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDY NNNRQQ--NEEIYQLNELWYMAKCLISLCDYLQQNDEVHPNIHPSSIFLTEAGQLKLVD---SSVLNLSSPQQKQHHMSFENSQTHAQMQFEQRYIAPEE .|. . . . ..... ... .|. .. .| . |. |.|.| ..|. | . .| . |.||| IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEV VIHQKNMNKYKL-SV-----------FQIGMTLLESALIQDCSYIYLEDDSINQNSLDFLINKVQEVYGDQFTTFLKKMLQLNPNNRPDIHEIYQ----- . .| .. . | .. . .. ...|. ... |..|.|| .|..|| . |. | L-------GYGKCKCDWWSCGCILYEMLCGYPPFP--------------------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI --QQFK .. KCHPWF |
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| Kinase | 30307.AA | NAK | 267-296 | 30 | 2e-06 | 17.08 | In-house | 270-299 (299) | Show / Hide |
Range on Protein: 267-296 Range on HMM: 270-299/299 Sequence Identity: 30% (9 aa) YGDQFTTFLKKMLQLNPNNRPDIHEIYQQQ | .|. . ..||. .|..||.|... .| YSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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| Kinase | 30307.AA | TKL-ciliate1 | 267-296 | 30 | 7e-06 | 16.05 | In-house | 250-279 (279) | Show / Hide |
Range on Protein: 267-296 Range on HMM: 250-279/279 Sequence Identity: 30% (9 aa) YGDQFTTFLKKMLQLNPNNRPDIHEIYQQQ . . | ....... ||| ||. || | CPQNFHNLMMRCWCQNPNKRPNFNEIIQIL |
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| Kinase | 30307.AA | AMPK | 275-298 | 37 | 1.8e-05 | 12.3 | In-house | 231-254 (254) | Show / Hide |
Range on Protein: 275-298 Range on HMM: 231-254/254 Sequence Identity: 37% (9 aa) LKKMLQLNPNNRPDIHEIYQQQFK .|.||| .|..| .||.| . .. IKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 30307.AA | CAMKL | 274-298 | 44 | 2e-05 | 13.12 | In-house | 273-297 (297) | Show / Hide |
Range on Protein: 274-298 Range on HMM: 273-297/297 Sequence Identity: 44% (11 aa) FLKKMLQLNPNNRPDIHEIYQQQFK ...|||| ||. || ||.| . . LIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 30307.AA | NEK | 261-298 | 22 | 2.2e-05 | 15.39 | In-house | 247-286 (286) | Show / Hide |
Range on Protein: 261-298 Range on HMM: 247-286/286 Sequence Identity: 22% (9 aa) NKVQEV--YGDQFTTFLKKMLQLNPNNRPDIHEIYQQQFK ..... | .. .. .||| .| .||.. .| .. | PPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | 30307.AA | PEK | 270-298 | 31 | 7.2e-05 | 12.05 | In-house | 627-655 (655) | Show / Hide |
Range on Protein: 270-298 Range on HMM: 627-655/655 Sequence Identity: 31% (9 aa) QFTTFLKKMLQLNPNNRPDIHEIYQQQFK .. .|...||...| .|| . .| |. | KQADFIQWMLSHDPQQRPSAQQILQHEFF |
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| Kinase | 30307.AA | Dicty3 | 271-293 | 34 | 0.0002 | 10.3 | In-house | 329-351 (351) | Show / Hide |
Range on Protein: 271-293 Range on HMM: 329-351/351 Sequence Identity: 34% (8 aa) FTTFLKKMLQLNPNNRPDIHEIY .. |... .| .||.|.|.||.. CKNFIQHCWQIDPNHRWDMHELI |
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| Kinase | 30307.AA | SgK071 | 255-297 | 26 | 0.000994 | 8.84 | In-house | 238-283 (283) | Show / Hide |
Range on Protein: 255-297 Range on HMM: 238-283/283 Sequence Identity: 26% (12 aa) SLDFLINKVQEVYG---DQFTTFLKKMLQLNPNNRPDIHEIYQQQF || . | . | . |. ||. || |. | .. . | SLKEILKTMEEKQIPDVDDYYQLLPFMLHINPQDRISIKDVMHITF |
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| Kinase | 30307.AA | SgK071 | 145-176 | 34 | 0.00586 | 6.13 | In-house | 119-150 (283) | Show / Hide |
Range on Protein: 145-176 Range on HMM: 119-150/283 Sequence Identity: 34% (11 aa) YLQQNDEVHPNIHPSSIFLTEAGQLKLVDSSV || . . .| . || |.||. ...|| | .. YLHHRNIIHRDLKPSNIYLTDQMHCKLQDFGI |
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| Kinase | 30307.AA | Dicty3 | 76-96 | 20 | 0.034953 | 2.78 | In-house | 56-79 (351) | Show / Hide |
Range on Protein: 76-96 Range on HMM: 56-79/351 Sequence Identity: 20% (5 aa) IQHSNLLKFYG--YSFNR-QNSIC ..|.. .|.|| |.... .. .. MRHPCIVKYYGACYCCDNNNDNHY |
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