Gene 19604 (Tetrahymena)

19604

Species: Tetrahymena
Alias: PreTt19604, 19604, 663, 59.m00242, 3680.m00099, TTHERM_00486730
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A5

Sequence

Name Sequence Type Origin Length Description Download
19604.AA Protein None 546 None Fasta, JSON
19604.kin_dom Protein Kinase Domain None 90 None Fasta, JSON
19604.NA RNA None 1641 None Fasta, JSON

Protein domain

Protein domains of 19604.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 19604.AA Ciliate-A5 47-273 33 3.2e-79 269.49 In-house 26-275 (275) Show / Hide 
Range on Protein: 47-273
Range on HMM: 26-275/275
Sequence Identity: 33% (84 aa)

SEVELKSIQDTAHSLNNLNHDSVVKLLRFKTSKKSELCS---------SYISNDLESDMQRRKKEE--VFYDESELWHIIVSTIAALAYLRSRGYEHGDI
.|  .| .|     ...|.|...|||..|.|.||.|.||         .|..|.||..||.||...  .||.|.|||.|....|....||......||||
DEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQELWYIMDCLISVCMYLQQNNICHGDI

KPSSILLSDQGRIKLLPSP----IVSSGNLNNYMQAFMGMRKAK--YLSPVLMKSLELQ----SQRPQHNCTKSDIFSLGLVILEAALLMEQ-DDIYDFV
.|..|.|...|..||  .          |.  |.|  ..|.     |||| ... ...     .||| || .|||.|.||...|| ... .   ..||. 
RPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYE

NFDINQQ-VLNSKIEFVQEKYSIQLAQFIQQMLIFDELERPDVDILFAYI
 | |    ..   |.....||| |.  || |||.|.|  |||   . .| 
TFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL
Kinase 19604.AA Ciliate-E4 41-152 27 1.9e-20 65.04 In-house 30-150 (150) Show / Hide 
Range on Protein: 41-152
Range on HMM: 30-150/150
Sequence Identity: 27% (33 aa)

KILQRDSEVELKSIQDTAHSLNNLNHDSVVKLLRFKTSKKSELCSS---------YISNDLESDMQRRKKEEVFYDESELWHIIVSTIAALAYLRSRGYE
|| .  .| ...  |        |||   .... .   | . .|||         |.  ||. . . .|.     ||||.| |  . | |..|| . .  
KIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVNIT

HGDIKPSSILLSDQGRIKLLP
|||.||| |....   .|.. 
HGDLKPSNIFFDQYFMVKIAD
Kinase 19604.AA Ciliate-E1 100-202 24 6.5e-09 25.62 In-house 100-202 (202) Show / Hide 
Range on Protein: 100-202
Range on HMM: 100-202/202
Sequence Identity: 24% (25 aa)

KKEEVFYDESELWHIIVSTIAALAYLRSRGYEHGDIKPSSILLSDQGRIKLLPSPIVSSGNLNNYMQAFMGMRKAKYLSPVLMKSLELQSQRPQHNCTKS
....  ... .. .||.  | .|..|.. .  |.||||. || ..||. ..    | . ...|.. |      . .| .|  ... |.. ...|    ||
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIF
||.
DIY
S_TKc 19604.AA S_TKc 25-273 15 6.8e-09 -46.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-273
Range on HMM: 1-231/231
Sequence Identity: 15% (45 aa)

LQFVKQVEDARYALVRKILQRD--SEVELKSIQDTAHS------LNNLNHDSVVKLLR-FKTSKKSELCSSYISN---DLESDMQRRKKEEVF--YDESE
 ......    .. |.|   ..   .| .| |    |       | . .|. .|||.  | . ..  ..  |...   || . ...|...     ..| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H

LWHIIVSTIAALAYLRSRGYEHGDIKPSSILLSDQGRIKL--------LPSPIVSSGNLNNYMQAFMGMRKAKYLSPVLMKSLELQSQRPQHNCTKSDIF
 ....  .. ||.|. |.|  | |.||. |||..  .||.        |                        .       . |.     .... |.|. 
ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTPWYMAPEVL----GYGKCKCDWW

SLGLVILEAAL-----LMEQDDIYDFVNFDINQQVLNSKIEFVQEKYSIQLAQFIQQMLIFDELERPDVDILFA---------YI
|.| .. | .        ... ... .                    | .. .||...| .|  .|| .  ...         ..
SCGCILYEMLCGYPPFP-QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 19604.AA Ciliate-B2 91-205 27 7.2e-09 16.88 In-house 86-197 (197) Show / Hide 
Range on Protein: 91-205
Range on HMM: 86-197/197
Sequence Identity: 27% (32 aa)

DLESDMQRRKKEEVFYDESELWHIIVSTIAALAYLRSRGYEHGDIKPSSILLSDQGRIKLLPSPIVSSGNLNNYMQAFMGMRKAKYLSPVLMKSLELQSQ
.|.. .|. .|.   . .  |  .|   | .|  .|.    | ||||. ||.. .|  ..    | |  . .|  .   |  | || ||  |.  . |. 
SLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKK-DNQQIKIKGFTK-KYASPEQMECDHNQTF

RPQHNCTKSDIFSLG
 .. .  .|||.|.|
VTNIDF-QSDIYSMG
Kinase 19604.AA MEK7 113-150 48 1.1e-07 22.17 In-house 106-144 (269) Show / Hide 
Range on Protein: 113-150
Range on HMM: 106-144/269
Sequence Identity: 48% (19 aa)

HIIVSTIAALAYLRSR-GYEHGDIKPSSILLSDQGRIKL
.. |..| || ||    |  | |.||| ||| ..| |||
KMVVAIINALHYLKEKHGIMHRDVKPSNILLDWRGNIKL
Kinase 19604.AA AGC 118-150 48 2.4e-07 13.51 In-house 162-196 (395) Show / Hide 
Range on Protein: 118-150
Range on HMM: 162-196/395
Sequence Identity: 48% (17 aa)

TIAALAYLRS-RGYEHGD-IKPSSILLSDQGRIKL
.. || || | .|. | | .||  ||| ..| |||
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKL
Kinase 19604.AA STE20 121-150 46 6.9e-07 21.53 In-house 129-158 (288) Show / Hide 
Range on Protein: 121-150
Range on HMM: 129-158/288
Sequence Identity: 46% (14 aa)

ALAYLRSRGYEHGDIKPSSILLSDQGRIKL
.|.|| |... | |||   |||...|..||
GLDYLHSNHIIHRDIKADNILLTEDGEVKL
Kinase 19604.AA PAKB 121-150 60 1e-06 20.32 In-house 107-136 (252) Show / Hide 
Range on Protein: 121-150
Range on HMM: 107-136/252
Sequence Identity: 60% (18 aa)

ALAYLRSRGYEHGDIKPSSILLSDQGRIKL
||||| ..|  | |||  ||||   ||.||
ALAYLHAQGVIHRDIKSDSILLTHDGRVKL
Kinase 19604.AA STE 107-150 37 6e-06 17.03 In-house 149-188 (359) Show / Hide 
Range on Protein: 107-150
Range on HMM: 149-188/359
Sequence Identity: 37% (17 aa)

DESELWHIIVSTIAA-LAYLRSRGYEHGDIKPSSILLSDQGRIKL
.||.. .|..... . |.|| | .. | ||||. |||     .||
PESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKL
Kinase 19604.AA WEE 197-212 62 2.9e-05 13.67 In-house 215-230 (297) Show / Hide 
Range on Protein: 197-212
Range on HMM: 215-230/297
Sequence Identity: 62% (10 aa)

TKSDIFSLGLVILEAA
.|.||||||..|.|.|
YKADIFSLGITIYELA
Kinase 19604.AA WEE 108-150 23 3.7e-05 13.35 In-house 110-173 (297) Show / Hide 
Range on Protein: 108-150
Range on HMM: 110-173/297
Sequence Identity: 23% (15 aa)

ESELWHIIVSTIAALAYLRSR-GYEHGDIKPSSILLSDQG--------------------RIKL
|...|.|.|  . .|... |. |  | ||||. |..| ..                    ..|.
EWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKI
Kinase 19604.AA STE 197-267 17 0.002659 7.66 In-house 247-349 (359) Show / Hide 
Range on Protein: 197-267
Range on HMM: 247-349/359
Sequence Identity: 17% (18 aa)

TKSDIFSLGLVILE----AALLMEQDDIYDFVNFDINQQVLN----------SKIEFVQ------------------EKYSIQLAQFIQQMLIFDELERP
||.|| |||..|.|       ...  . .   .. .|. . .              . .                  .|.|  . .||.. |. |  .||
TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRP

DVD
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TAS