Gene 16384 (Tetrahymena)

16384

Species: Tetrahymena
Alias: 3836.m02052, 6.m00458, 1018, 16384, PreTt16384, TTHERM_00085360
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A4

Sequence

Name Sequence Type Origin Length Description Download
16384.AA Protein None 1279 None Fasta, JSON
16384.kin_dom Protein Kinase Domain None 248 None Fasta, JSON
16384.NA RNA None 3840 None Fasta, JSON

Protein domain

Protein domains of 16384.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 16384.AA Ciliate-A4 231-486 55 1.2e-167 551.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 231-486
Range on HMM: 1-284/284
Sequence Identity: 55% (158 aa)

MKHFKQLDKGSFGKVDLYFIEIDYILKENLQIQQQNLLLSSQNSNQSYSTQASNETIQNSIQMLKQKSDYIFTNSSADYQNSMFSEGGLQQKTSKENQTW
  ... ...||||.|||||.||||..|.|.|.||||.....||.||.|.....|..||.|.||..||....|......|.|.|||....||...|.||.|
FYYYTSIGEGSFGTVDLYFFEIDYYQKCNFQDQQQNQQTWHQNNNQNYNQYNQNQYIQSSQQMQQQKQQFSFNQDQQQYNNMMFSQEMQQQQYQKFNQKW

QNSHLSLQQSTSN--------------------MKKQLLPVAGKQINVQSEFIRELYIMETVNCEYMPKLLNYDVDNQILFMELGLCNLYDLKIDSIQNE
..||....|....                    ||.|.||||.|.|..|.|||||||||.||.|||||||..||.|.||||||.|||.|||||.||.||.
SQSHQQIYQYQNQDMHNYIQKQQNVYYQKIQQFMKMQYLPVACKKIKTQEEFIRELYIMQTVQCEYMPKLFYYDIDQQILFMEMGLCSLYDLKQDSEQNN

YDFTDEFTYSILINLIQAVESLLKN--YNQKEKKQQPLFHSDIKPQN-----IMLTVKKS-EDQLLNTQLILIDYGGASFQLDD
|.|.||||||||||||||.||.|.|  |||.|.|.||||||||||||     |||||||| |||....||.|||.|||||||.|
YCFSDEFTYSILINLIQAIESMLSNKAYNQQEQKHQPLFHSDIKPQNKIQLQIMLTVKKSKEDQQSQIQLMLIDFGGASFQLED
Kinase 16384.AA DAPK 448-465 55 9.6e-05 8.67 In-house 126-143 (264) Show / Hide 
Range on Protein: 448-465
Range on HMM: 126-143/264
Sequence Identity: 55% (10 aa)

HSDIKPQNIMLTVKKSED
| |.|||||||| .....
HLDLKPQNIMLTDRNIPQ
Kinase 16384.AA S_TKc 342-588 12 0.000148 -110.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 342-588
Range on HMM: 1-231/231
Sequence Identity: 12% (37 aa)

SNMKKQL-----------------LPVAGKQINVQSEFIRELYIMETVNCEYMPKLLNYDV-DNQILFMELGLC---NLYDLKIDSIQNEYD--FTDEFT
  . ...                   || |.|.    ..||. |..  ....  ||. . . |.  ..||.      .|.|.  .   . ..  |.   .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HA

YSILINLIQAVESLLKNYNQKEKKQQPLFHSDIKPQNIMLTVKKSEDQLLNTQLILIDYGGASFQLDDYWSYYTPAFVCNQLWQKLVNSKNNWEYLTWPQ
 ...  ...|.| .          ..   | |.||.||.|.           .. ..| | | .                                    
RFYMYQICCALEYC---------HSHGIIHRDLKPENILLDE----------HIKICDFGLARQL---------------------------------TT

VRYAEIYAA---CRSVQF----------LLIESLE-SNLFKKENTGKFIEKYSQSYPKTCRILENVLIKNKS--FLIFSDYR-------DILY
.     | |   . .  .          .|.| |    .|   .  . ..|     |  . .... | |. .    .    .       .   
FCGTPWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 16384.AA DRAK 443-467 48 0.000887 6.99 In-house 117-141 (259) Show / Hide 
Range on Protein: 443-467
Range on HMM: 117-141/259
Sequence Identity: 48% (12 aa)

QQPLFHSDIKPQNIMLTVKKSEDQL
|.   | | |||||.||  ..|| .
QRNIVHLDLKPQNILLTSEYPEDDI
Kinase 16384.AA Ciliate-E3 443-458 50 0.001554 7.23 In-house 121-136 (202) Show / Hide 
Range on Protein: 443-458
Range on HMM: 121-136/202
Sequence Identity: 50% (8 aa)

QQPLFHSDIKPQNIML
.. . ||||||.|| .
EKNIIHSDIKPDNILV
Kinase 16384.AA CDK-Unclassified 446-459 71 0.00232 6.76 In-house 142-155 (324) Show / Hide 
Range on Protein: 446-459
Range on HMM: 142-155/324
Sequence Identity: 71% (10 aa)

LFHSDIKPQNIMLT
. | ||||||||.|
IMHRDIKPQNIMIT
Kinase 16384.AA Ciliate-E2 450-497 15 0.003577 6.72 In-house 186-255 (365) Show / Hide 
Range on Protein: 450-497
Range on HMM: 186-255/365
Sequence Identity: 15% (13 aa)

DIKPQNIMLTVKKSEDQLLNTQLILIDYGGASFQLDD--------------YWS----------------------YYTPAFVC
||||.||..             . .|| | . .. ||              . .                      ..|| ...
DIKPENILF-------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMA
Kinase 16384.AA Ciliate-A5 442-459 55 0.005305 6.36 In-house 116-133 (275) Show / Hide 
Range on Protein: 442-459
Range on HMM: 116-133/275
Sequence Identity: 55% (10 aa)

KQQPLFHSDIKPQNIMLT
.|  ..| ||.|||| ||
QQNNICHGDIRPQNICLT
Kinase 16384.AA Ciliate-A1 448-462 46 0.006619 5.65 In-house 124-138 (301) Show / Hide 
Range on Protein: 448-462
Range on HMM: 124-138/301
Sequence Identity: 46% (7 aa)

HSDIKPQNIMLTVKK
|.|.|||||..  ..
HRDLKPQNILIHFDD
Kinase 16384.AA Dicty3 448-487 24 0.076958 1.63 In-house 135-191 (351) Show / Hide 
Range on Protein: 448-487
Range on HMM: 135-191/351
Sequence Identity: 24% (14 aa)

HSDIKPQNIMLTVKKS-------EDQLL-----------NTQLILIDYGGASFQLDDY
| |||..||||  ...       . ..             . . |||. |.|.... |
HRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDF-GLSKNISYY
Kinase 16384.AA Ciliate-E2 231-245 40 0.118896 1.42 In-house 1-15 (365) Show / Hide 
Range on Protein: 231-245
Range on HMM: 1-15/365
Sequence Identity: 40% (6 aa)

MKHFKQLDKGSFGKV
 |  |.. .|.||.|
YKFIKKIGQGNFGSV
Kinase 16384.AA Ciliate-A4 881-1144 35 1.3e-75 246.12 In-house 5-284 (284) Show / Hide 
Range on Protein: 881-1144
Range on HMM: 5-284/284
Sequence Identity: 35% (99 aa)

KSKDKGSFGQVDLYFCEI-----EQQFLNNSIQQDIKIEDMEIEQSINMQQTLYPFKQKEYSYNLRSFKNKMSEFNLSSQSLGSKNSKNNTLASTLIVDE
.| ..||||.||||| ||     ..    .  ||       ... . |  |..    |   .    || .   . | .  | ..  .. .   ..    .
TSIGEGSFGTVDLYFFEIDYYQKCNFQDQQQNQQTWHQNNNQNYNQYNQNQYIQSSQQMQQQKQQFSFNQDQQQYNNMMFSQEMQQQQYQKFNQKWSQSH

NKISNTISS-----RDNNESILISSTIASNNKQQYFPVAGKKFSNKEEFIRELFIMNQISSTYKPKIIEQDIEEQIIFLELGLCNLYNLKIDSQINNYKL
 .|    .       . . .. .   .  ... || |||.||  ..|||||||.||  . . | ||   .||. || |.|.|||.||.||.||  |||..
QQIYQYQNQDMHNYIQKQQNVYYQKIQQFMKM-QYLPVACKKIKTQEEFIRELYIMQTVQCEYMPKLFYYDIDQQILFMEMGLCSLYDLKQDSEQNNYCF

TDEFTFQVLINIFNAIESLLGN--INPKTQTPFPIFHSDIKPQN-----IILTATQHLEDKSPEIKLLLIDFGGSSSDIQD
.||||...|||...||||.| |   |...|   |.|||||||||     |.||  .  ||.  .|.|.|||||| | .. |
SDEFTYSILINLIQAIESMLSNKAYNQQEQKHQPLFHSDIKPQNKIQLQIMLTVKKSKEDQQSQIQLMLIDFGGASFQLED
Kinase 16384.AA Ciliate-E2 1102-1157 16 2.2e-05 14.42 In-house 181-257 (365) Show / Hide 
Range on Protein: 1102-1157
Range on HMM: 181-257/365
Sequence Identity: 16% (15 aa)

PIFHSDIKPQNIILTATQHLEDKSPEIKLLLIDFG--------------GSSSDIQDYWS----------------------YYTPAFVCQE
.|.| ||||.||..              . .||||              .. . .  . .                      ..|| ... |
NIIHRDIKPENILF--------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE
Kinase 16384.AA Dicty9 1103-1150 32 0.00011 13.58 In-house 145-194 (356) Show / Hide 
Range on Protein: 1103-1150
Range on HMM: 145-194/356
Sequence Identity: 32% (17 aa)

IFHSDIKPQNIILTATQHLEDKSPEIKLLLIDFGGSSSDIQDYWS----YYT
|.| |||| ||..       | .....  |.||| |.  . .  .    |||
IIHRDIKPENIFFKRY--NNDGNIDLDCCLCDFGISQFVYTHNKNDQDLYYT
Kinase 16384.AA DRAK 1103-1136 47 0.000169 9.27 In-house 120-147 (259) Show / Hide 
Range on Protein: 1103-1136
Range on HMM: 120-147/259
Sequence Identity: 47% (16 aa)

IFHSDIKPQNIILTATQHLEDKSPEIKLLLIDFG
| | | ||||| ||  . ..|    ||  ..|||
IVHLDLKPQNILLTSEYPEDD----IK--ICDFG
Kinase 16384.AA Dicty3 1103-1141 32 0.000225 10.13 In-house 133-188 (351) Show / Hide 
Range on Protein: 1103-1141
Range on HMM: 133-188/351
Sequence Identity: 32% (18 aa)

IFHSDIKPQNIILTATQ-HLED----------------KSPEIKLLLIDFGGSSSD
| | |||..||.|     |. .                 | ||.. ||||| |...
IIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKNI
Kinase 16384.AA DAPK 1103-1136 47 0.000626 6.38 In-house 124-152 (264) Show / Hide 
Range on Protein: 1103-1136
Range on HMM: 124-152/264
Sequence Identity: 47% (16 aa)

IFHSDIKPQNIILTATQHLEDKSPEIKLLLIDFG
| | |.||||| ||     ..  ..||  .||||
ICHLDLKPQNIMLTDR---NIPQGDIK--IIDFG
Kinase 16384.AA Ciliate-A1 1103-1115 61 0.002821 6.93 In-house 122-134 (301) Show / Hide 
Range on Protein: 1103-1115
Range on HMM: 122-134/301
Sequence Identity: 61% (8 aa)

IFHSDIKPQNIIL
| |.|.|||||..
ILHRDLKPQNILI
Kinase 16384.AA Ciliate-A5 1103-1116 71 0.003603 6.95 In-house 120-133 (275) Show / Hide 
Range on Protein: 1103-1116
Range on HMM: 120-133/275
Sequence Identity: 71% (10 aa)

IFHSDIKPQNIILT
|.| ||.||||.||
ICHGDIRPQNICLT
Kinase 16384.AA Ciliate-E3 1103-1113 81 0.004305 5.83 In-house 124-134 (202) Show / Hide 
Range on Protein: 1103-1113
Range on HMM: 124-134/202
Sequence Identity: 81% (9 aa)

IFHSDIKPQNI
| ||||||.||
IIHSDIKPDNI
Kinase 16384.AA CDK-Unclassified 1103-1136 45 0.009267 4.75 In-house 142-171 (324) Show / Hide 
Range on Protein: 1103-1136
Range on HMM: 142-171/324
Sequence Identity: 45% (16 aa)

IFHSDIKPQNIILTATQ-HLEDKSPEIKLLLIDFG
| | ||||||| .| .       ||  .| ..|||
IMHRDIKPQNIMITNNNSTV---SP--MLKIADFG