Gene 16383 (Tetrahymena)
16383
Group:
Other
Family:
Ciliate-A4
Sequence
Protein domains of 16383.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 16383.AA | Ciliate-A4 | 358-644 | 43 | 2.8e-112 | 367.68 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 358-644 Range on HMM: 1-284/284 Sequence Identity: 43% (128 aa) FQYYCKLDSGSFGQVDLYLLEFENKIPSKQEIQKNEKQNGGSHRNIEQKDAYYKKSSTYFQSTENEIGDFERQ-VKQLELNQNTIQLKQQRSHESTKEDS | || ... ||||.|||| .| ... . .... | . | . . | .. |.|| . . . | ....| . | |. . . FYYYTSIGEGSFGTVDLYFFEI-DYYQKCNFQDQQQNQQTWHQNNNQNYNQY--NQNQYIQSSQQMQQQKQQFSFNQDQQQYNNMMF----SQEMQQQQY NGNRLQNSKLVDTSINSDIQNTPI-MNKIRAKAKQLSINKQYNYQQEQLILPVAGKMIKNFNEFVRELYIMQTVQFDMMPKLIGQDIDQRILYIELGLCS .. ..| .| ...|.. . | . | . ..| ... | .||||.| ||. ||.|||||||||| |||| ..||||.||..|.|||| QKFNQKWS----QSHQQIYQYQNQDMHNYIQKQQNVYYQKIQQFMKMQ-YLPVACKKIKTQEEFIRELYIMQTVQCEYMPKLFYYDIDQQILFMEMGLCS LYDLKQDSLKRGYKLDDHFTFSILVNIIQAIESMLSN--YNDSKQKSQPLFHSDIKPQN-----IVLTIKKNKQTNQSEIKLMLIDFGGASFELED ||||||||....|...|.||.|||.|.|||||||||| ||...||.|||||||||||| |.||.||.|...||.|.|||||||||||.||| LYDLKQDSEQNNYCFSDEFTYSILINLIQAIESMLSNKAYNQQEQKHQPLFHSDIKPQNKIQLQIMLTVKKSKEDQQSQIQLMLIDFGGASFQLED |
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| Kinase | 16383.AA | S_TKc | 499-771 | 14 | 1.2e-05 | -94.21 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 499-771
Range on HMM: 1-231/231
Sequence Identity: 14% (46 aa)
YQQEQLI-----------------LPVAGKMIKNFNEFVRELYIMQTVQFDMMPKLIGQDIDQRILYIELGLCSL--YDLKQDSLKRGYK-----LDDHF
|. ..| || |.|| . . ||. |.. . . ||.. | ||. . .|. ||.. |||.. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H
TFSILVNIIQAIESMLSNYNDSKQKSQPLFHSDIKPQNIVLTIKKNKQTNQSEIKLMLIDFGGASFELEDYWSYYTPAFVSPYLWERLVNSKFKQDFLTW
. ... |..|.| . |. | |.||.|| |. ....||| | . . || ...| .
ARFYMYQICCALEYC---------HSHGIIHRDLKPENILLDE-----------HIKICDFGLARQL---TTFCGTPWYMAPEVL---------------
PEVRYAE----------VYAACRTVQYLMLEERHKDLFKKENCQIFIRQYEVSYPKTCKILEKVYQSIQDYKIFSDYKNVFNNQDFYSINQRIDFNQEKI
| . . . . | . .. .||| .. |. .. . ..|. .
---GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ
----FEISKFY
. .
DEWDIKCHPWF
|
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| Kinase | 16383.AA | DAPK | 605-636 | 50 | 2.8e-05 | 10.17 | In-house | 126-152 (264) | Show / Hide |
Range on Protein: 605-636 Range on HMM: 126-152/264 Sequence Identity: 50% (16 aa) HSDIKPQNIVLTIKKNKQTNQSEIKLMLIDFG | |.||||| || .... |..|| .|||| HLDLKPQNIMLT---DRNIPQGDIK--IIDFG |
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| Kinase | 16383.AA | DYRK2 | 605-641 | 51 | 4.6e-05 | 12.05 | In-house | 125-154 (318) | Show / Hide |
Range on Protein: 605-641 Range on HMM: 125-154/318 Sequence Identity: 51% (19 aa) HSDIKPQNIVLTIKKNKQTNQSEIKLMLIDFGGASFE | | || ||.| || |.| || .|||| || HCDLKPENILL-----KQWNRSGIK--VIDFGSSCFE |
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| Kinase | 16383.AA | Dicty3 | 605-636 | 32 | 5.5e-05 | 12.18 | In-house | 135-183 (351) | Show / Hide |
Range on Protein: 605-636 Range on HMM: 135-183/351 Sequence Identity: 32% (16 aa) HSDIKPQNIVLTIKKNKQTNQS-----------------EIKLMLIDFG | |||..||.| ....| | ||.. ||||| HRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFG |
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| Kinase | 16383.AA | Ciliate-E2 | 607-656 | 16 | 0.000124 | 11.81 | In-house | 186-256 (365) | Show / Hide |
Range on Protein: 607-656 Range on HMM: 186-256/365 Sequence Identity: 16% (14 aa) DIKPQNIVLTIKKNKQTNQSEIKLMLIDFGGASFELED--------------YWS----------------------YYTPAFVSP ||||.||.. . .|||| . . .| . . ..|| ...| DIKPENILF--------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAP |
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| Kinase | 16383.AA | NEK1 | 605-638 | 45 | 0.000307 | 10.8 | In-house | 127-168 (276) | Show / Hide |
Range on Protein: 605-638 Range on HMM: 127-168/276 Sequence Identity: 45% (19 aa) HSDIKPQNIVLTIKKNK--------QTNQSEIKLMLIDFGGA | |||.|||.||| || | | .. | ||| | HRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIA |
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| Kinase | 16383.AA | Ciliate-E2a | 607-636 | 35 | 0.000328 | 8.32 | In-house | 127-154 (275) | Show / Hide |
Range on Protein: 607-636 Range on HMM: 127-154/275 Sequence Identity: 35% (11 aa) DIKPQNIVLT-IKKNKQTNQSEIKLMLIDFG |.||.|| .. ..||.. ....|||| DLKPENILFKNCSKNSI---QNSDIKIIDFG |
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| Kinase | 16383.AA | Ciliate-C4 | 605-636 | 42 | 0.000625 | 8.1 | In-house | 163-194 (361) | Show / Hide |
Range on Protein: 605-636 Range on HMM: 163-194/361 Sequence Identity: 42% (14 aa) HSDIKPQNIVLTIK-KNKQTNQSEIKLMLIDFG |.|||| ||.. | . . | . .. ||||| HCDIKPENILVKYKSDFGGSNNIQ-QVKLIDFG |
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| Kinase | 16383.AA | IRE | 605-636 | 33 | 0.000638 | 9.0 | In-house | 139-169 (292) | Show / Hide |
Range on Protein: 605-636 Range on HMM: 139-169/292 Sequence Identity: 33% (11 aa) HSDIKPQNIVLTIKK-NKQTNQSEIKLMLIDFG | |.||.|| . . |... .....|. ||| HRDLKPHNILIHMNRPNQHG--ENNRFMISDFG |
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| Kinase | 16383.AA | CMGC | 607-641 | 25 | 0.000956 | 7.16 | In-house | 209-254 (513) | Show / Hide |
Range on Protein: 607-641 Range on HMM: 209-254/513 Sequence Identity: 25% (12 aa) DIKPQNIVLTIKK-------------NKQTNQSEIKLMLIDFGGASFE |.||.|| .. .. |.. |. .| ..||| | .. DLKPENILINHNCELITRMMWKSEDWNPC--QKNGRLKICDFGLARWY |
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| Kinase | 16383.AA | CMGC | 358-372 | 26 | 0.073864 | 0.84 | In-house | 1-15 (513) | Show / Hide |
Range on Protein: 358-372 Range on HMM: 1-15/513 Sequence Identity: 26% (4 aa) FQYYCKLDSGSFGQV .. |. .|..|.| YEIIKKIGEGTYGVV |
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