Gene 25405 (Tetrahymena)
25405
Group:
Other
Family:
Ciliate-A2
Sequence
Protein domains of 25405.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 25405.AA | Ciliate-A2 | 31-288 | 47 | 3.5e-156 | 525.17 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 31-288 Range on HMM: 1-272/272 Sequence Identity: 47% (130 aa) GSGAYGQVMTAKE---ENGEEVAIKIVSVFDEIDS-IDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKG-EMSLQEFVDKKLNQG--MS |.|..|.|..... .|.|..||||.|..|.||. |..|||.|.|.|||||..|.|||||.|..|||.|..|||.|||. |.|||...||. ||. .. GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP EKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYN-IKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVM-TNFNSEEKKSQKIYQNFD ...||..|.|.|.||.|||.|||||||.||.|.|.|.|.. ||||||||||...|....|.|..|..|||.||.|||.... ...|.|..|.|.|.|.|. DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFM GDVWAFGVCMYLLGGASFLHVLQLT----QGKETFQLSKLVSIEINQILLNTLQLDPKLRP-SIDKIIQDFK ||.||||.|.|.||||.. |...|| .....| ........|||....|..|||.|| ||..|..... GDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH |
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| Kinase | 25405.AA | Ciliate-E6 | 75-228 | 38 | 2.4e-55 | 174.45 | In-house | 1-154 (154) | Show / Hide |
Range on Protein: 75-228 Range on HMM: 1-154/154 Sequence Identity: 38% (60 aa) AQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEMSLQEFVD-KKLNQGMSEK-LFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLA .|.|. | ||||. | ..|| ||| ||. ||.|| . .|... . .|.| ..|...|..||||||||| |.||| |||..|||.||||. IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ KEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFG ..|.| .|..|. .. ..|.||| . . . ....| . |. . || | . QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSK-DQQSKHY-KVNWTQEGDIWSVC |
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| S_TKc | 25405.AA | S_TKc | 24-288 | 24 | 1.5e-39 | 138.67 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 24-288 Range on HMM: 1-231/231 Sequence Identity: 24% (70 aa) TVVNPNAGSGAYGQVMTAKEEN-GEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEM---SLQEFVDKKLN . |.||.|.|. ... . |..|||||.. . |..| | |.. |||||| ... || ..... || . .| .. .|. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR QG----MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQK .| ..| ... |...|..|.||.. . ||. |.|||. .||.||||||... . . | ..| .|||| HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-------------- IYQNFDGDVWAFGVCMYLLGGASFLHVLQLTQGKETFQLSKLVSIEINQILLNTLQLDPKLRPSIDKIIQ--------DFK | . |.|..|...| . . | ...|.. . | | ... . || ||. ||.. .. | . GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 25405.AA | CAMK | 31-177 | 17 | 8.8e-35 | 108.97 | In-house | 3-248 (425) | Show / Hide |
Range on Protein: 31-177
Range on HMM: 3-248/425
Sequence Identity: 17% (44 aa)
GSGAYGQVMTAKEE-NG------------EEVAIKIVSVFDEIDSI----------------------DEQKLKEIKSEAQFLQMCH-------HPNIVS
|.|..|.| ... .. ..|||||.. |. .....|....| . ..... ||||..
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK
YKGEFQ------------LGSC--------YFIKM------EKGEM--SLQEFVDKKLN-------------QGMSEKLFVKLALQMLSAIQYLHSKNYV
.. |. ... | . ||. | ... .. . ..|. .. |..||..|.||.| |
LYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIV
LRDISLKNVLLDKD-----------------YNIKLCDFGLAKEINP
||. . |.|||.. .|||..|||.|....|
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDP
|
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| Kinase | 25405.AA | STE | 31-290 | 18 | 3.3e-32 | 111.06 | In-house | 8-359 (359) | Show / Hide |
Range on Protein: 31-290
Range on HMM: 8-359/359
Sequence Identity: 18% (66 aa)
GSGAYGQVMTAKEEN----------------GEEVAIKIVSVFDE-----------IDSIDEQKLKEIKSEAQFLQMCH--HPNIVSYKGEFQLG-----
|.||.|.| .|. . || .|||.... .. ..........|. | .... |. ||||| | | . .
GKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHK
--SCYFIKMEKGE-MSLQEFVD------KKLN------QGMSEKLFVKLALQMLSA-IQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLA
. .| || . || .... | || . ..|.. . . | | . .||||.... ||| |.|| .||||||... ... .|
NDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMA
------------TQA-FLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFGVCM-------YLLGGASFLHVLQLTQ-------------
|.. .. | . |||. . . . .. |.| .| .. . . . . .. ...
NIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQG-R-----DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC
----GKETFQL-----------------SKLVSIEINQILLNTLQLDPKLRPSIDKIIQD-FKNI
. ... .. .| | .. . . || ||. ||. .. ... . |
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
|
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| Kinase | 25405.AA | TKL | 30-232 | 17 | 1.2e-30 | 107.58 | In-house | 1-280 (364) | Show / Hide |
Range on Protein: 30-232
Range on HMM: 1-280/364
Sequence Identity: 17% (52 aa)
AGSGAYGQVMTAKEEN---------GEEVAIKIVSV--FDEIDS-----------------IDEQKLKEIKSEAQFLQMCH--HPNIVSYKG--------
|||..|.| .| . |..||.|. .. || .. .|.. . . | . ..| |||||...|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
-----------------EFQ-LGS-CYFIKMEKGEMSLQEFVDKKLNQGMSEKLFVKLALQMLSAIQYLHS--------KNYVLRDISLKNVLLDKDYN-
|. || .... .....||.. ....|||| .. . ||. ||.|.|....
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTN
-------------IKLCDFGLAKEINPQLA---------------TQAFLQSQVKGVLFYFPPEVLVMTNFNS-----EEKKSQKIYQNFDGDVWAFGVC
.|.|||||...... ... . . | . . .|||| ...... .| . .. . ||..||..
VSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIV
MY
..
LW
|
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| Kinase | 25405.AA | Pkinase | 31-229 | 25 | 1.6e-30 | 109.03 | Pfam | 8-200 (293) | Show / Hide |
Range on Protein: 31-229
Range on HMM: 8-200/293
Sequence Identity: 25% (54 aa)
GSGAYGQVMTAKEENGEE-VAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCHHPNIVSYKGEFQLGSCYFIKMEKGEM-----SLQEFVD---KKLNQG
|||..|.| ... . .. ||.||... .| .. |..... ||.| .....||||| ... |. .. . . || |. .| ... ..
GSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-
MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNI----KLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIY
.||. . ..|.|....|.||.. . ||. . |.|.|....| |.||||||| .. . . ... . | ..| .|||. |
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFC-GTPWYMAPEVIR-----------GGQY
QNFDGDVWAFGV
|.|..|.
YGPKVDMWSCGC
|
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| Kinase | 25405.AA | AGC | 31-232 | 18 | 2.6e-30 | 74.24 | In-house | 8-296 (395) | Show / Hide |
Range on Protein: 31-232 Range on HMM: 8-296/395 Sequence Identity: 18% (56 aa) GSGAYGQVMTAKE-------ENGEEVAIKIVSVFDE-IDSIDEQKLKEIKSE------------AQFLQMCH----------HPNIVS-YKGEFQLGSC- | |..|.|. ... .|. |.|... .. | ....... ...| . |..|. ||.||. . || . GKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLK-KKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHT -YFIKME------------KG-EMSLQEFVDKKLNQG-MSEKLFVKLALQ-------MLSAIQYLHS-KNYVLRD-ISLKNVLLDKDYNIKLCDFGLAKE .. || | |. |. . . ...| ..|. | . ...|..|||| .... || . . |.|||.| .|||.||||.|| YLYFVMEYMPRYVNDLYCGGGCELFLHLQGR--RKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKE INPQ-----------------------------------------------LATQAFLQSQVKG--VLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVW .. . .. . | | .||.| .. | | GMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----------------YGKACDWW A--FGVCMY . .|..|| SFGLGCLMY |
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| Kinase | 25405.AA | CAMKL | 31-177 | 28 | 4.8e-30 | 92.95 | In-house | 8-181 (297) | Show / Hide |
Range on Protein: 31-177 Range on HMM: 8-181/297 Sequence Identity: 28% (49 aa) GSGAYGQVMTAKE-EN-GEEVAIKIVSVF----DEIDSID------EQKLKEIKSEAQFLQMCH---HPNIVSYKGEFQLGSC------YFIKMEKGEMS | |..|.| |. . ||.|||||. . |.. . |... |. |.| ..| . ||||.. .. .. ... || . GKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG ---LQEFVDKKLNQG--MSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDY--NIKLCDFGLAKEINP |.....|. . . |.|. .. |..||..|.||.. | ||| . |.|||.. |||..|||.. .. | EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRP |
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| Kinase | 25405.AA | Ciliate-E2 | 24-285 | 16 | 2.5e-25 | 83.9 | In-house | 1-361 (365) | Show / Hide |
Range on Protein: 24-285 Range on HMM: 1-361/365 Sequence Identity: 16% (64 aa) TVVNPNAGSGAYGQVMTAKE-ENGEEVAIK--------------IVSVFDEIDSIDEQKLKEIKSEAQFLQ----------------MCHHPNIVSYKGE .. |.|..|.| .| ......||| . . .. .. ......||.| . .. ||||. .. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ---LGSCYFIKMEKGEMSLQEFV---DKKLNQG------MSEKLFVKLALQMLS---------------AIQYLHSKN-YVLRDISLKNVLLDKDYNI || ..|.. ..|... .|| |. ..|| .. | |. |..|||||| . ||| . |.|. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLCDFGLAKEINPQ-----------LATQAF-----------------LQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNFDGDVWAFGVCMYLLGG |..||||.|..... . .. . .. .. | . | .||.| . . . . ... . .. |.|..||..| . KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---QKQKGYDYKCDIWSLGVILYEMLF ASFLHVLQLTQGKETFQLSKLVSIEIN--------------------------QILLN----TLQLDPKLRPS-IDKIIQ . .| | |... ... . || ||. |.. ...|.. GKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN |
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| Kinase | 25405.AA | ULK | 123-232 | 24 | 4.9e-16 | 53.43 | In-house | 124-243 (324) | Show / Hide |
Range on Protein: 123-232
Range on HMM: 124-243/324
Sequence Identity: 24% (32 aa)
SEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYN------------IKLCDFGLAKEINPQLATQAFLQSQV-----KGVLFYFPPEVLVMTN
||. .. | ... ..||..|.. ||| . | |. .. .|..|||.|| .. | .|..| || | |..|
SEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQIL----
FNSEEKKS--QKIYQNFDGDVWAFGVCMY
.. || | .. |.| .|. .|
-----QGQGEQKPYYDYKCDIWSLGCIFY
|
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| Kinase | 25405.AA | TK-Unique | 123-232 | 31 | 1.6e-15 | 50.08 | In-house | 129-230 (294) | Show / Hide |
Range on Protein: 123-232 Range on HMM: 129-230/294 Sequence Identity: 31% (35 aa) SEKLFVKLALQMLSAIQYLHS--KNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQLATQAFLQSQVKGVLFYFPPEVLVMTNFNSEEKKSQKIYQNF |.|... | | .. .||.| |. | ||.. .|||| |...|.||||.|.... .. .|| . . . .||.| . ...| . SPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIRWMAPESLKCY---------HGMYHTT DGDVWAFGVCMY .|||.||| |. KSDVWSFGVLMW |
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| Kinase | 25405.AA | TyrKc | 24-287 | 20 | 4.5e-15 | 20.98 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 24-287
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)
TVVNPNAGSGAYGQVMTAKEENGEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMC--HHPNIVSYKGEFQLG-------SCYFIKMEKGEM-SLQEF
. . |.||.|.|. .. ..||.| . .... .||. . . |||||| | . ..| || . .|...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY
VDKKLNQGMSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEINPQ----LATQAFLQS---QVK--GVLFYFPPEVLVMT
|. .. . | ... ..| . .||||||.. ||. |.|..... .| .||||...| ... .. . | . .||..
LRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---
NFNSEEKKSQKIYQNFDGDVWAFGVCMY--------LLGG-----ASFLHVLQLTQGKETFQLSKL--------VSIEINQILLNTLQLDPKLRPSIDKI
... .. |||.|||||. | | .|... . . . . |. || . . ||. ||. |
--------NYGKF-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI
IQDF
...|
HECF
|
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| Kinase | 25405.AA | Pkinase_Tyr | 103-175 | 32 | 4.2e-11 | 38.23 | Pfam | 89-161 (270) | Show / Hide |
Range on Protein: 103-175 Range on HMM: 89-161/270 Sequence Identity: 32% (24 aa) MEKGEMSLQEFVDKK--LNQGMSEKLFVKLALQMLSAIQYLHSKNYVLRDISLKNVLLDKDYNIKLCDFGLAKEI |..| .| .. |. .| . | .. ..| .. .||.|||.. ||. .|.|.... .| ||||||. | MPHG--DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI |
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| Kinase | 25405.AA | ULK | 31-90 | 22 | 8.4e-08 | 23.82 | In-house | 8-81 (324) | Show / Hide |
Range on Protein: 31-90 Range on HMM: 8-81/324 Sequence Identity: 22% (17 aa) GSGAYG-QVMTAK-EEN---GEEVAIKIVSVFDEIDSIDEQK----LKEIKSEAQFLQMCH---HPN--IVSYK |.|..| .| .. ... .. ||.|... . ... || .. .|.| | ... . ||| || .. GKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLY |
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| Kinase | 25405.AA | Pkinase_Tyr | 31-91 | 24 | 3e-06 | 21.97 | Pfam | 8-71 (270) | Show / Hide |
Range on Protein: 31-91 Range on HMM: 8-71/270 Sequence Identity: 24% (17 aa) GSGAYGQVMTAKEE-----NGEEVAIKIVSVFDEIDSIDEQK--LKEIKSEAQFLQMC-HHPNIVSYKG |.||.|.|. .. .. .||.|.. .. ... ... .||. . ||||||.. | GEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG |
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| Kinase | 25405.AA | TK-Unique | 253-287 | 22 | 3e-06 | 17.54 | In-house | 259-294 (294) | Show / Hide |
Range on Protein: 253-287 Range on HMM: 259-294/294 Sequence Identity: 22% (8 aa) QLSKLV-SIEINQILLNTLQLDPKLRPSIDKIIQDF .. . . | |. ... ...|..|. |||...|.. . PQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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| Kinase | 25405.AA | TK-Unique | 24-88 | 26 | 0.00025 | 10.97 | In-house | 1-68 (294) | Show / Hide |
Range on Protein: 24-88 Range on HMM: 1-68/294 Sequence Identity: 26% (18 aa) TVVNPNAGSGAYGQVMTAKEEN--GEEVAIKIVSVFDEIDSIDEQKLKEIKSEAQFLQMCH-HPNIVS .|. . |.||.||| ... .. ... . |.| | |. .... .. ..|.|... |||||. LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQ |
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| Kinase | 25405.AA | Pkinase | 254-287 | 30 | 0.007972 | 11.07 | Pfam | 259-293 (293) | Show / Hide |
Range on Protein: 254-287 Range on HMM: 259-293/293 Sequence Identity: 30% (11 aa) LSKLVSIEINQILLNTLQLDPKLRPSIDKIIQD--F . ...| | ... . |..||| ||... | |. | F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 25405.AA | CAMKL | 258-286 | 31 | 0.066506 | 1.69 | In-house | 267-294 (297) | Show / Hide |
Range on Protein: 258-286 Range on HMM: 267-294/297 Sequence Identity: 31% (9 aa) VSIEINQILLNTLQLDPKLRPSIDKIIQD || . ... || .|. ||.|. | .. VS-DCRDLIRKMLQVNPEKRPTIHQIMNH |
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| Kinase | 25405.AA | TKL | 273-287 | 40 | 0.192447 | 0.97 | In-house | 350-364 (364) | Show / Hide |
Range on Protein: 273-287 Range on HMM: 350-364/364 Sequence Identity: 40% (6 aa) DPKLRPSIDKIIQDF ||. ||| ..|.. . DPEKRPSFQEILKRL |
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| Kinase | 25405.AA | Pkinase_Tyr | 223-232 | 70 | 0.208478 | 5.39 | Pfam | 196-205 (270) | Show / Hide |
Range on Protein: 223-232 Range on HMM: 196-205/270 Sequence Identity: 70% (7 aa) DVWAFGVCMY |||.|||.|. DVWSFGVLMW |
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| Kinase | 25405.AA | Pkinase_Tyr | 261-287 | 25 | 0.50799 | 4.08 | Pfam | 244-270 (270) | Show / Hide |
Range on Protein: 261-287 Range on HMM: 244-270/270 Sequence Identity: 25% (7 aa) EINQILLNTLQLDPKLRPSIDKIIQDF || .... . ||. ||. |.... EIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| TPR | 25405.AA | TPR | 478-511 | 38 | 2e-08 | 35.27 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 478-511 Range on HMM: 1-34/34 Sequence Identity: 38% (13 aa) FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN .|.|| .|| . ..|. | ...|||||. .| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 478-511 | 41 | 6.1e-08 | 31.7 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 478-511 Range on HMM: 1-34/34 Sequence Identity: 41% (14 aa) FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN .| || .||.. ..|. | ...|||||| .| AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_1 | 25405.AA | TPR_1 | 648-681 | 26 | 4.1e-07 | 28.82 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 648-681 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY ..| . ||..... |. |.||...|.|. .. .. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | 25405.AA | TPR | 444-477 | 26 | 2e-06 | 28.77 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 444-477 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI . ...| ||.|.. |..|| ......| |. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 444-477 | 26 | 2e-06 | 26.51 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 444-477 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI . ..| ||.|.. |..|| ......| |. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 478-511 | 38 | 2e-06 | 26.6 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 478-511 Range on HMM: 1-34/34 Sequence Identity: 38% (13 aa) FSPYYCLGIIYYERSEFDQSISYFNKALELNSSN . .|.|| .||.. ..|. | |..|||.|. | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | 25405.AA | TPR | 648-681 | 26 | 2e-06 | 28.94 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 648-681 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY . | . ||..... |. |.||...|.|. .. .. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 648-681 | 29 | 1e-05 | 24.42 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 648-681 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) PNAQFLLGQVFEQIGKMDKAIKYFQEAIMIQAKY . | ..|||. .. |. |.||.|...|. . .. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 716-749 | 26 | 1.4e-05 | 23.51 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 716-749 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE |.... || .|.|.. . .|| .. ....| |. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 716-749 | 29 | 1.6e-05 | 23.65 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 716-749 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE |.... ||..|.|.. . .||.|. ....| | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 444-477 | 29 | 2.1e-05 | 23.22 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 444-477 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) PYSILQIGKCYFKKKMYEDAITSFKQVIKLLPTI .. ..|.||.|.. |..|| .....|| |. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | 25405.AA | TPR | 716-749 | 26 | 2.5e-05 | 24.94 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 716-749 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) AKIYNELGKIYEKKQYLSQAINYFSECISLKPSE |.... || .|.|. . .||........| |. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 376-409 | 35 | 0.000269 | 19.29 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 376-409 Range on HMM: 1-34/34 Sequence Identity: 35% (12 aa) EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN |. ..| ||...|...| |..|.| |.|.| AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | 25405.AA | TPR | 376-409 | 35 | 0.000434 | 20.83 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 376-409 Range on HMM: 1-34/34 Sequence Identity: 35% (12 aa) EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN |....| || ..|...|. ..||.| |.|.| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 376-409 | 35 | 0.000624 | 17.71 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 376-409 Range on HMM: 1-34/34 Sequence Identity: 35% (12 aa) EIALSCMGYYYYEKNDLKQAMCYLQKCLNLNPKN |.. .|. ||.......| ..||.| |||.| AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 512-545 | 29 | 0.001201 | 16.99 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 512-545 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) QNCLYSLAKVYLETFNYSNAIEILNTLVRLFPSN ..| |...|.. .| ||| .. ...|.| | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 580-613 | 29 | 0.002526 | 15.59 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 580-613 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN |.. |.. |. ... . ||.|.| ...|| | AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | 25405.AA | TPR | 580-613 | 26 | 0.007139 | 16.79 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 580-613 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN . |...|. |... . . ||.|.| .....| | AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 682-715 | 29 | 0.024123 | 12.38 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 682-715 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) ELPYIDLSQIYRKKGQYDDALFICKLALQNNIKS . | |.|.|.|.||.|. .. ||. . . AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 580-613 | 23 | 0.026596 | 12.23 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 580-613 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) ILALNCLAYYYFLKQQNQLAIQCLQSSIKVNPCN |...|. |. ... . ||.... ..| .| | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | 25405.AA | TPR | 614-647 | 11 | 0.037471 | 13.12 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 614-647 Range on HMM: 1-34/34 Sequence Identity: 11% (4 aa) FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF .|.. ....... |....|| . ... . .. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 614-647 | 14 | 0.0393 | 11.63 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 614-647 Range on HMM: 1-34/34 Sequence Identity: 14% (5 aa) FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF ..|.....|... |....|| . . . . .. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR | 25405.AA | TPR | 512-545 | 29 | 0.064119 | 11.07 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 512-545 Range on HMM: 1-34/34 Sequence Identity: 29% (10 aa) QNCLYSLAKVYLETFNYSNAIEILNTLVRLFPSN ..| |. .|. .| ||| .. ..| |.| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR | 25405.AA | TPR | 410-443 | 14 | 0.069181 | 10.78 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 410-443 Range on HMM: 1-34/34 Sequence Identity: 14% (5 aa) YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY ..|. .. .. .. ..|| . ...|.. . |. AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR | 25405.AA | TPR | 682-715 | 26 | 0.076625 | 10.39 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 682-715 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) ELPYIDLSQIYRKKGQYDDALFICKLALQNNIKS . | ..|.|.|.||.|. .. ||. . . AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 614-647 | 14 | 0.165505 | 9.25 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 614-647 Range on HMM: 1-34/34 Sequence Identity: 14% (5 aa) FRAYFYQAQILLSEGKHEDAILSAKYSMQQNSKF .|.. ...... |....|| . . | .. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | 25405.AA | TPR | 546-579 | 26 | 0.206313 | 6.61 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 546-579 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN .. |...| .| .. .|. ||.|...|.| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 546-579 | 26 | 0.212655 | 8.87 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 546-579 Range on HMM: 1-34/34 Sequence Identity: 26% (9 aa) DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN . |...| . .. .. |. || |..||.| AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR | 25405.AA | TPR | 342-375 | 23 | 0.259813 | 5.73 | SMART | 1-34 (34) | Show / Hide |
Range on Protein: 342-375 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) DQYLALLGLTHLEQYQCEESRSISQKCLSINPKN ... ||. .. . . .| ||.|...|.| AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 515-545 | 35 | 0.521554 | 7.51 | Pfam | 4-34 (34) | Show / Hide |
Range on Protein: 515-545 Range on HMM: 4-34/34 Sequence Identity: 35% (11 aa) LYSLAKVYLETFNYSNAIEILNTLVRLFPSN .| |. .|.. || ||| .. ..| |.| WYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 308-341 | 20 | 0.632621 | 7.36 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 308-341 Range on HMM: 1-34/34 Sequence Identity: 20% (7 aa) QTELFQQAQKEIDNHKYQEAQVTLERLVKINTHN .....| . . .|.|| .|...|.. | AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 690-715 | 34 | 0.795517 | 6.87 | Pfam | 9-34 (34) | Show / Hide |
Range on Protein: 690-715 Range on HMM: 9-34/34 Sequence Identity: 34% (9 aa) QIYRKKGQYDDALFICKLALQNNIKS ..|.|.|.||.|. .. ||. | . NCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 546-579 | 23 | 0.916703 | 6.79 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 546-579 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) DLYLATLALAYSEIKDEQKVMEFSQKSLQINPQN .. |...| . .| .. |. .|.|...|.| AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_1 | 25405.AA | TPR_1 | 410-443 | 17 | 2.607966 | 5.07 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 410-443 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY ..|.. .. .. .....|| . ...|.. | |. AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN |
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| TPR_1 | 25405.AA | TPR_1 | 366-375 | 60 | 8.380836 | 3.3 | Pfam | 25-34 (34) | Show / Hide |
Range on Protein: 366-375 Range on HMM: 25-34/34 Sequence Identity: 60% (6 aa) QKCLSINPKN ||.|..||.| QKALELNPNN |
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| TPR_2 | 25405.AA | TPR_2 | 342-375 | 23 | 12.213169 | 2.81 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 342-375 Range on HMM: 1-34/34 Sequence Identity: 23% (8 aa) DQYLALLGLTHLEQYQCEESRSISQKCLSINPKN .. .||. ...| . .| . .|.|...|.| AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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| TPR_2 | 25405.AA | TPR_2 | 410-443 | 17 | 21.226883 | 1.96 | Pfam | 1-34 (34) | Show / Hide |
Range on Protein: 410-443 Range on HMM: 1-34/34 Sequence Identity: 17% (6 aa) YRALTYKAFVLSNQQKLDEELLTLKEAISYNQNY .|. . . .. .|...|| . ...|.... |. AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN |
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