Gene 23053 (Tetrahymena)

23053

Species: Tetrahymena
Alias: 977, 7.m00502, PreTt23053, TTHERM_00105530, 23053
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A2

Sequence

Name Sequence Type Origin Length Description Download
23053.AA Protein None 1065 None Fasta, JSON
23053.kin_dom Protein Kinase Domain None 267 None Fasta, JSON
23053.NA RNA None 3198 None Fasta, JSON

Protein domain

Protein domains of 23053.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 23053.AA Ciliate-A2 32-287 47 2e-158 532.59 In-house 1-272 (272) Show / Hide 
Range on Protein: 32-287
Range on HMM: 1-272/272
Sequence Identity: 47% (130 aa)

GKGGFGTVLFVED--TQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMRECSHKNIIELRDEYVIDLYHFIQMDLC-EFSLEGWIK--KNGTKHIP
|.|.||.|.|||.  ...|.|||.|.|.. |...|||.|.|||.|..|||....|.|.||....||..|..|.||||..| |.||. ||.  .|..|.||
GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP

YANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGV-VKLCDFGLAKKTQSAQYSMQFSAAGPKGVFAYFPPEVLKE---------GSQEVKQSKE
...|...|.||.|..|||||.||..||||.|||||..... .||||||||||.|....|..|... |||||.|.|||....         ..|..||...
DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFM

ADIWALGICLKLFGGLQIQKVMYLVSCSEFDKLIAFDSPNLDAKCNKLIQYILICDPKQRP-NINQIREKMH
.||||.||||...||...|....|..|.........|.||||.|||..||.||.||||.|| .|.|||...|
GDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 23053.AA S_TKc 25-290 24 9.7e-41 142.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-290
Range on HMM: 1-231/231
Sequence Identity: 24% (69 aa)

KILKKDGGKGGFGTVLFVEDTQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMRECSHKNIIELRDEYVIDLYHFIQMDLCEF---SLEGWIKKNG
  . .  |||.||.|  . ..  . ..|.|                 .. .|| ||...  |.||. | | ..   . .. |..|.    .|   |||.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

TKH----IPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLAKKTQSAQYSMQFSAAGPKGVFAYFPPEVLKEGSQEVKQSK-E
..     .|     .|..||....||.|... | |||   |||...  ..|.||||||..                |   | .||||       . .| .
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL-------GYGKCK

ADIWALGICL-------KLFGGLQIQKVMYLVSCSEFDKLIAFDSPNLDAKCNKLIQYILICDPKQRPNINQIRE-----KMHQWF
.|.|..|..|        .|   |.|... ..                .  .  .|. .|  ||..|| . .. .     |.|.||
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 23053.AA Ciliate-E6 78-223 30 1.8e-35 110.42 In-house 1-154 (154) Show / Hide 
Range on Protein: 78-223
Range on HMM: 1-154/154
Sequence Identity: 30% (47 aa)

AQIMRECSHKNIIELRDEYVIDLYHFIQMDLCEFSLEGWIKKNGTKHIPYAN--FTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLA
.|  ..|.|.||.   |.  |. |.||.|  ||..|. ||...  | .   |  |   ..|.  .||||| .||.   .. .|| . |   .|.||||. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KKTQSAQYSMQFSAAGPKGVFAYFPPEVLK------EGSQEVKQSKEADIWALG
.   . | . .| |  .   . |.||| .       .  . |.. .|.||| ..
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC
Kinase 23053.AA Ciliate-E2-Unclassified 32-226 24 1.2e-31 107.04 In-house 8-260 (352) Show / Hide 
Range on Protein: 32-226
Range on HMM: 8-260/352
Sequence Identity: 24% (61 aa)

GKGGFGTVLFVEDTQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMRE-----------------CSHKNIIELRDEYVI--DLYHFIQMDLCE-F
|.||||.|  ... ... .|| |   .  ...||. . |     .|...| .                  .|.... ....|.   . . .| |..||  
GQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEGG

SLEGWIKKNGT---------------KHIPYANFT-----YYAQQIIDGVEYLHNQN-YIVRDLSVRNILINKAG---VVKLCDFGLAK-----------
.|. .|||...               |...  .       .|. ||..| |||| .|  | ||.   |||... |    .|..|||..|           
DLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTN

---KTQSAQYSMQFSAAGPKGVFA-YFPPEVLKEGSQEVKQSKEADIWALGICL
   |.|  .. |. . .|  .    | .||||..  .. . ....|||.||..|
QQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVIL
Kinase 23053.AA Ciliate-E2 24-290 20 1.4e-29 98.67 In-house 1-365 (365) Show / Hide 
Range on Protein: 24-290
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

LKILKKDGGKGGFGTVLFVEDTQKNAKYA----------------VKAQYVGDSNNQKIDQAKLQSCQREAQ-------------IMRECSHKNIIELRD
 |..||  |.|.||.|  ... ... ..|                ||....   ...| .   . . ... .             |... .|.|||.. .
YKFIKK-IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

EYV--IDLYHFIQMDLCEF-SLEGWIKKNGTK-----------------HIPYANFT-------YYAQQIIDGVEYLHNQN-YIVRDLSVRNILINKAGV
 .    | . .. |..|.  .|. .||.| .|                 .| .  .        .|. .||...||||..|  | ||.   |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKLCDFGLAKKTQ---------SAQYSMQFSAAGPKGVFA-------------------YFPPEVLKEGS-----QEVKQSKEADIWALGICLK--LFGG
.|..||||.|| .         . .. ..|     .. .                    | .||.|. ..     ..   ....|||.||..|   ||| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

L----QIQKVMYLVSCSEFDKLIAF-------DSPNLDAKCNKLIQY----ILICDPKQRPN-INQIREKMHQWF
.    ||..  .  .| |..|  .        .  ... .|  ||.     .| .||..|.. ..||  . |.||
PPFQQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI--LNHPWF
Kinase 23053.AA Ciliate-C7 29-191 28 2.1e-27 85.29 In-house 2-164 (164) Show / Hide 
Range on Protein: 29-191
Range on HMM: 2-164/164
Sequence Identity: 28% (47 aa)

KDGGKGGFGTVLFVEDTQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMRECS-HKNIIELRDEYVIDLYHFIQMDLCEF-SLEGWIKKNGTKHIP
.  |.| .|.||  .| ..|  ||.|   |.|.. . |||  ....|.|..|.  |. . . . | ...  . . ..... |   .|.  |..|  |   
RFLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGN-IDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLN

YANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLAKKTQSAQYSMQFSAAG
  ..  ||. |  |  | | .|..|.||.  ||||   |. ..|||||| .    .  .|..  .
EISAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNGNAVVCDFGLADNLTQKS-KYQINQYM
Kinase 23053.AA CAMK 32-224 16 9.2e-26 79.39 In-house 3-322 (425) Show / Hide 
Range on Protein: 32-224
Range on HMM: 3-322/425
Sequence Identity: 16% (54 aa)

GKGGFGTVLFVEDTQKN------------AKYAVKAQYV---------------------GDSNNQKIDQAKLQSCQREAQIMRECS-------HKNIIE
|.|.||.|  ..... .             |.|.|                         .......... .... .|| .||. ..       |.||| 
GRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIK

LRDEYV--------IDLY------------HFIQM---DLC---EF--SLEGWIKKNGT-------------KHIPYANFTYYAQQIIDGVEYLHNQNYI
| . |         .| |             .. |   ..|   |    |  .|...|              .... .   .| .||...|.|.|..| .
LYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIV

VRDLSVRNILINKA-----------------GVVKLCDFGLAKKTQSAQYSM-------------------QFSAAGPKGVFAYFP-PEVLKEGSQ----
 |||   |||...                  . .|..|||.|.| .. . ..                         . |  .| . ||||.  ..    
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

------EVKQSKEADIWALGI
      .   ....|.|..|.
NATDEEKPYYGPKCDMWSCGV
Kinase 23053.AA STE 25-226 21 2.6e-23 79.27 In-house 1-258 (359) Show / Hide 
Range on Protein: 25-226
Range on HMM: 1-258/359
Sequence Identity: 21% (58 aa)

KILKKDGGKGGFGTVLFVEDT------QKNAK---------YAVKAQYVGDSN----------NQKIDQAKLQSCQREAQIMRECS--HKNIIELRDEYV
  . .  |||.||||    .       ... .         .|.|   . ..|          ...... ..|. ..| .||..|.  |.||..  . |.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IDL-------YHFIQMDLCEF-SLEGWIK-KNGT-----------KHIPYANFTYYAQQIIDG-VEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLAK
 .        . .| | ...  ||.  || | |.           ...|     |...||. |  .|||....| ||.   |||.     |||||||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KTQS---------------AQYSMQFSAAGPKGVFAYFPPEVLKEGSQE--VKQSKEADIWALGICL
. ..                . ..  . .|      .  |||.. ..|    . .  .||| ||...
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP----WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 23053.AA ULK 32-226 26 4.2e-23 77.56 In-house 8-246 (329) Show / Hide 
Range on Protein: 32-226
Range on HMM: 8-246/329
Sequence Identity: 26% (65 aa)

GKGGFGTVLFVEDTQK----NAKYAVKAQYVGDSNNQKID---QAKLQSCQREAQIMRECS----HKN----IIELRDEYVID--LYHFIQMDLCEF-SL
||| ||.|   .. ..    | |.|.|       |... .   |  .|. ..| .||..      |||    |..| | .  .   ...| |..|.   |
GKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDL

EGWIKKNGT--------KHIPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKA------------GVVKLCDFGLAKKTQSA----QYSMQFS-
|  ||||..        |...      . .||. |  .|| .|.| ||.   ||||..             ||.|..|||.||. ..     |  | .. 
EQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVN

AAGPK---GVFAYFPPEVLKEGSQEVKQS-KEADIWALGICL
    |   |   |  |..|..   . ... ...||| ||. .
E---KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 23053.AA CAMKL 32-224 22 1.1e-22 69.14 In-house 8-224 (297) Show / Hide 
Range on Protein: 32-224
Range on HMM: 8-224/297
Sequence Identity: 22% (50 aa)

GKGGFGTVLFVEDTQK-NAKYAVKAQYVGDSN-NQKID--------QAKLQSCQREAQIMRECS---HKNIIELRDEYVIDLY------HFIQMDLCEFS
|||.||.|   ....  . |.|.|       . .....        ....   .||.|||.  .   |.||| | . .  . .       .. | .|.  
GKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

---LEGWIKKNGTKH--IPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAG--VVKLCDFGLAKKTQS--AQYSMQFSAAGPKGVFAYFPPEV
   |  .|.|.| .   .|      | .||...|.|.|... . ||.   |||. . |  ..|..|||.. . .    ..   ..     |  .| .||.
EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFC--GSPPYMAPEI

LKEGSQEVKQSKEADIWALGI
.. . ..    ...|||..|.
FQGN-NKPYDGPKVDIWSCGV
Kinase 23053.AA ULK 32-226 25 2.2e-22 76.24 In-house 8-242 (324) Show / Hide 
Range on Protein: 32-226
Range on HMM: 8-242/324
Sequence Identity: 25% (62 aa)

GKGGFG-TVLFVEDTQK---NAKYAVKAQYVGDSNNQKIDQAKLQ--------SCQREAQIMRECS---HKN--IIELRDEYVIDLY--HFIQMDLCEF-
||| || .|   .. ..   | ..|.|       . .|. . |..        . ..| |||..     |.|  |..| | .  . .  ..| |..|.  
GKGSFGVKVYKGRNKKTNTQNQYVACKMI-----DKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGG

SLEGWIKKNGT-------KHIPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKA------------GVVKLCDFGLAKKTQ---SAQYSM----
 ||  ||||..       | ..      . .||. |  .||..|.| ||.   ||||..             ||.|..|||.||. .    .|  .    
DLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCV

-QFSAAGPK---GVFAYFPPEVLKEGSQEVKQS-KEADIWALGICL
 .      |   |   |  |..|..   . ... ...||| ||. .
NE------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF
Kinase 23053.AA Pkinase 32-224 27 5.6e-20 71.71 Pfam 8-200 (293) Show / Hide 
Range on Protein: 32-224
Range on HMM: 8-200/293
Sequence Identity: 27% (57 aa)

GKGGFGTVLFVEDTQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMRECSHKNIIELRDEYVIDLYHFIQMDLCEF-----SLEGWIK--KNGTKH
|.|.||.|    .   . ..|||   . . . .|  .. .    .|.|||....|.||..|.| .  . .  . |..||      .|  .|.  ..|.  
GSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGC--

I--PYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVV----KLCDFGLAKKTQSAQYSMQFSAAGPKGVFAYFPPEVLKEGSQEVKQSKEAD
.  ..     |. ||. |.||.|... | |||   ||||.. |..    |.|||||||. .   |  .  . .. |   | .|||..      . ....|
FYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVD

IWALGI
.|..|.
MWSCGC
Kinase 23053.AA TyrKc 25-286 21 1.4e-13 -3.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-286
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

KILKKDGGKGGFGTVLFVEDTQKNAKYAVKAQYVGDSNNQKIDQAKLQSCQREAQIMREC--SHKNIIELRDEYVID-------LYHFIQMDLCEF-SLE
  |.|  | | ||.|   . .    . |||    .           ..   |||.||..   .|.||. |    . .         ..| | ...  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

GWIKKNGTKHIPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLAKKTQSA--------QYSMQFSAAGPK-GVFAYFPPEVLK
  ..|.. | .. . . ... || .| |||| .|.| |||  ||.|... ..|| .||||...  .          |... .  |         .||.. 
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

EGSQEVKQSKEADIWALGICL--------KLFGG-----LQIQKVMYLVSCSEFDKLIAFDS------PNLDAKCNKLIQYILICDPKQRPNINQIREKM
   .. | . . |.|. |.|.        .   |     .  | |. .|   . . .   ..      .   ..  ....     ||..||. ..|.|..
---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV--KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 23053.AA Pkinase_Tyr 118-226 28 7.9e-13 44.08 Pfam 99-204 (270) Show / Hide 
Range on Protein: 118-226
Range on HMM: 99-204/270
Sequence Identity: 28% (32 aa)

KKN--GTKHIPYANFTYYAQQIIDGVEYLHNQNYIVRDLSVRNILINKAGVVKLCDFGLAKKT-QSAQY-SMQFSAAGPKGVFAYFPPEVLKEGSQEVKQ
.|.  . ....      ...|| .| |||...|.| |||  ||.|... .||| ||||||.      .|  .. ..  |       .||....|      
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP---IKWMAPECINYGK----F

SKEADIWALGICL
. . |.|. |...
TTKSDVWSFGVLM
Kinase 23053.AA CAMKL 255-290 33 6e-06 14.72 In-house 265-297 (297) Show / Hide 
Range on Protein: 255-290
Range on HMM: 265-297/297
Sequence Identity: 33% (12 aa)

PNLDAKCNKLIQYILICDPKQRPNINQIREKMHQWF
. ..  |  ||. .|  .|..||.| ||  ..| |.
YHVS-DCRDLIRKMLQVNPEKRPTIHQI--MNHPWM
Kinase 23053.AA CAMK 254-290 29 0.000745 7.51 In-house 392-425 (425) Show / Hide 
Range on Protein: 254-290
Range on HMM: 392-425/425
Sequence Identity: 29% (11 aa)

SPNLDAKCNKLIQYILICDPKQRPNINQIREKMHQWF
. .... |  ||. .|  ||..|..| |. .  |.|.
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLN--HPWM
Kinase 23053.AA Ciliate-E2-Unclassified 254-290 35 0.004531 6.52 In-house 318-352 (352) Show / Hide 
Range on Protein: 254-290
Range on HMM: 318-352/352
Sequence Identity: 35% (13 aa)

SPNLDAKCNKLIQYILICDPKQRPNINQIREKMHQWF
||.    .|.|.| .|  .|..|....||  . |.||
SPEAKDFINDLLQKMLKKNPNKRITFEQI--LNHPWF
Kinase 23053.AA Pkinase 255-290 38 0.005187 11.73 Pfam 260-293 (293) Show / Hide 
Range on Protein: 255-290
Range on HMM: 260-293/293
Sequence Identity: 38% (14 aa)

PNLDAKCNKLIQYILICDPKQRPNINQIREKMHQWF
.|..  | ..| ..|  |||.||.. || .  | ||
HNWSEECKDFIKWCLCKDPKKRPTAEQILQ--HPWF
Kinase 23053.AA Pkinase_Tyr 76-92 50 0.168861 5.7 Pfam 52-69 (270) Show / Hide 
Range on Protein: 76-92
Range on HMM: 52-69/270
Sequence Identity: 50% (9 aa)

REAQIMREC-SHKNIIEL
|||.||..  .|.||. |
REAKIMKQLGHHPNIVRL
Kinase 23053.AA Pkinase_Tyr 272-286 40 0.718517 3.57 Pfam 256-270 (270) Show / Hide 
Range on Protein: 272-286
Range on HMM: 256-270/270
Sequence Identity: 40% (6 aa)

DPKQRPNINQIREKM
||..||   .|.|..
DPEDRPTFSEIHEQL
TPR_2 23053.AA TPR_2 440-461 18 0.451011 7.88 Pfam 13-34 (34) Show / Hide 
Range on Protein: 440-461
Range on HMM: 13-34/34
Sequence Identity: 18% (4 aa)

ANCNFKKAEQYFQDARDIDEDD
.. ....|..|.. |  .|...
KQGDYDEAIEYYEKALKLDPNN
TPR 23053.AA TPR 427-461 17 0.59301 2.58 SMART 1-34 (34) Show / Hide 
Range on Protein: 427-461
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

INYLITLGFLEACANCNFKKAEQYFQDARDIDEDD
. ..  || .   .. ....|....| | ..|...
AEAWYNLGNC-YYKMGDYDEAIECYQKALELDPNN
TPR_1 23053.AA TPR_1 443-461 21 0.889921 6.7 Pfam 16-34 (34) Show / Hide 
Range on Protein: 443-461
Range on HMM: 16-34/34
Sequence Identity: 21% (4 aa)

NFKKAEQYFQDARDIDEDD
|...|....| | ......
NYDEAIECYQKALELNPNN
TPR_2 23053.AA TPR_2 499-532 26 0.035645 11.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 499-532
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

WRIHYYQSWLYFLQQKYQLSNESLQTALGLELNS
....|.. ..|. |..|.   | .. || |. | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 23053.AA TPR 533-566 11 0.213461 6.48 SMART 1-34 (34) Show / Hide 
Range on Protein: 533-566
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

PQIYSLKAVLSCIQGNNQLGLSEIEKAIQLNKDQ
..... ....   .|. .  .   .||..|. . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 23053.AA TPR 499-532 26 0.829222 1.3 SMART 1-34 (34) Show / Hide 
Range on Protein: 499-532
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

WRIHYYQSWLYFLQQKYQLSNESLQTALGLELNS
....| .  .|... .|.   | .| || |. | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 533-566 17 1.512972 6.02 Pfam 1-34 (34) Show / Hide 
Range on Protein: 533-566
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

PQIYSLKAVLSCIQGNNQLGLSEIEKAIQLNKDQ
. .. . ...   ||. .  .   |||..|. . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 23053.AA TPR_1 533-566 17 7.641735 3.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 533-566
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

PQIYSLKAVLSCIQGNNQLGLSEIEKAIQLNKDQ
..... ....   .|| .  .   .||..|| . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 23053.AA TPR_1 569-603 22 0.007805 13.88 Pfam 1-34 (34) Show / Hide 
Range on Protein: 569-603
Range on HMM: 1-34/34
Sequence Identity: 22% (8 aa)

PQILFRKGYIYHKILKNQKESLAAYKEALDICQKD
.......|..|.| ..| .| ...|..||..  ..
AEAWYNLGNCYYK-MGNYDEAIECYQKALELNPNN
TPR 23053.AA TPR 569-603 20 0.03482 13.4 SMART 1-34 (34) Show / Hide 
Range on Protein: 569-603
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

PQILFRKGYIYHKILKNQKESLAAYKEALDICQKD
.......| .|.| ... .| ...|..||..  ..
AEAWYNLGNCYYK-MGDYDEAIECYQKALELDPNN
TPR 23053.AA TPR 604-637 29 0.074448 10.5 SMART 1-34 (34) Show / Hide 
Range on Protein: 604-637
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

MMTLFNITQLYNEQQNNIQAESFGQKALQLYPNS
  ...|. ..|  . .  .|. . ||||.| || 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 569-603 20 0.130986 9.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 569-603
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

PQILFRKGYIYHKILKNQKESLAAYKEALDICQKD
. .... | .| | ... .| ...|..|| .  ..
AEAWYNLGQCYYK-QGDYDEAIEYYEKALKLDPNN
TPR_2 23053.AA TPR_2 616-637 36 2.630467 5.17 Pfam 13-34 (34) Show / Hide 
Range on Protein: 616-637
Range on HMM: 13-34/34
Sequence Identity: 36% (8 aa)

EQQNNIQAESFGQKALQLYPNS
.|..  .|. . .|||.|.|| 
KQGDYDEAIEYYEKALKLDPNN
TPR_1 23053.AA TPR_1 628-637 70 8.162659 3.34 Pfam 25-34 (34) Show / Hide 
Range on Protein: 628-637
Range on HMM: 25-34/34
Sequence Identity: 70% (7 aa)

QKALQLYPNS
||||.| || 
QKALELNPNN
TPR_1 23053.AA TPR_1 806-839 29 1.7e-08 33.63 Pfam 1-34 (34) Show / Hide 
Range on Protein: 806-839
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

PIASFQLGIIYKDKKMYPQAIPYFENAIRINPKD
. | ..|| .|  .. | .|| ... |...||..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 23053.AA TPR 806-839 26 5.5e-08 33.78 SMART 1-34 (34) Show / Hide 
Range on Protein: 806-839
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PIASFQLGIIYKDKKMYPQAIPYFENAIRINPKD
. | ..|| .|  .. | .|| ... |....|..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 806-839 32 2e-06 26.61 Pfam 1-34 (34) Show / Hide 
Range on Protein: 806-839
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

PIASFQLGIIYKDKKMYPQAIPYFENAIRINPKD
. | ..|| .|  .. | .|| |.| |....|..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 23053.AA TPR_2 738-771 26 2.6e-05 22.88 Pfam 1-34 (34) Show / Hide 
Range on Protein: 738-771
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

VNAQICLGFIHKQKNEDQLAAQEFQKAIQIDPNS
. |  .|| .. .... . |.. ..||...||| 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 23053.AA TPR_1 738-771 26 0.000107 20.38 Pfam 1-34 (34) Show / Hide 
Range on Protein: 738-771
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

VNAQICLGFIHKQKNEDQLAAQEFQKAIQIDPNS
..|   || .. .... . | . .|||....|| 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 23053.AA TPR 772-805 35 0.000589 20.39 SMART 1-34 (34) Show / Hide 
Range on Protein: 772-805
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

HRAYLELGIVNLKMKKDDEAISNFLKAYNLNKDE
 .|.. || . .||.. ||||  . ||  |. . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 23053.AA TPR 738-771 29 0.00064 20.27 SMART 1-34 (34) Show / Hide 
Range on Protein: 738-771
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

VNAQICLGFIHKQKNEDQLAAQEFQKAIQIDPNS
. |  .|| .. .... . | . .|||...||| 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 772-805 32 0.00066 17.91 Pfam 1-34 (34) Show / Hide 
Range on Protein: 772-805
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

HRAYLELGIVNLKMKKDDEAISNFLKAYNLNKDE
 .|.  || . .|... ||||  . ||  |. . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 23053.AA TPR_1 772-805 38 0.000736 17.46 Pfam 1-34 (34) Show / Hide 
Range on Protein: 772-805
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

HRAYLELGIVNLKMKKDDEAISNFLKAYNLNKDE
 .|.  || . .||.. ||||  . ||  || . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 23053.AA TPR_1 715-737 47 0.003467 15.11 Pfam 12-34 (34) Show / Hide 
Range on Protein: 715-737
Range on HMM: 12-34/34
Sequence Identity: 47% (11 aa)

EKTKRYDRAQIYYKRALEQNPNM
.| ..|| |  .|..||| ||| 
YKMGNYDEAIECYQKALELNPNN
TPR_2 23053.AA TPR_2 715-737 43 0.0054 14.68 Pfam 12-34 (34) Show / Hide 
Range on Protein: 715-737
Range on HMM: 12-34/34
Sequence Identity: 43% (10 aa)

EKTKRYDRAQIYYKRALEQNPNM
.| ..||.|  ||..||. .|| 
YKQGDYDEAIEYYEKALKLDPNN
TPR 23053.AA TPR 703-737 31 0.028757 14.13 SMART 1-34 (34) Show / Hide 
Range on Protein: 703-737
Range on HMM: 1-34/34
Sequence Identity: 31% (11 aa)

VDLLIQIGYLEMEKTKRYDRAQIYYKRALEQNPNM
.. . ..| . . | ..|| |  .|..||| .|| 
AEAWYNLGNCYY-KMGDYDEAIECYQKALELDPNN
TPR 23053.AA TPR 669-702 26 0.069 10.79 SMART 1-34 (34) Show / Hide 
Range on Protein: 669-702
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

IDSLEAIAKIYVERNLYPQAIQYYETILESDVVN
.. .  .. .|  .. | .||..|.  || |  |
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 669-697 27 0.338718 8.32 Pfam 1-29 (34) Show / Hide 
Range on Protein: 669-697
Range on HMM: 1-29/34
Sequence Identity: 27% (8 aa)

IDSLEAIAKIYVERNLYPQAIQYYETILE
 . . .....| ... | .||.|||  |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALK
TPR_1 23053.AA TPR_1 669-697 24 0.365256 8.05 Pfam 1-29 (34) Show / Hide 
Range on Protein: 669-697
Range on HMM: 1-29/34
Sequence Identity: 24% (7 aa)

IDSLEAIAKIYVERNLYPQAIQYYETILE
 . .  .. .| ... | .||..|.  ||
AEAWYNLGNCYYKMGNYDEAIECYQKALE
TPR_1 23053.AA TPR_1 654-668 46 0.549817 7.43 Pfam 20-34 (34) Show / Hide 
Range on Protein: 654-668
Range on HMM: 20-34/34
Sequence Identity: 46% (7 aa)

AIKYYQKAVEADSGD
||..||||.| .  .
AIECYQKALELNPNN
TPR_2 23053.AA TPR_2 654-668 46 0.971992 6.7 Pfam 20-34 (34) Show / Hide 
Range on Protein: 654-668
Range on HMM: 20-34/34
Sequence Identity: 46% (7 aa)

AIKYYQKAVEADSGD
||.||.||.. | ..
AIEYYEKALKLDPNN
TPR_2 23053.AA TPR_2 875-903 31 0.007477 14.18 Pfam 1-29 (34) Show / Hide 
Range on Protein: 875-903
Range on HMM: 1-29/34
Sequence Identity: 31% (9 aa)

PDAYRMLGDCFYQKDDRQQAEFYLRKTIE
..|...||.| |.. | ..|. |..| ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALK
TPR_1 23053.AA TPR_1 875-903 27 0.025087 12.11 Pfam 1-29 (34) Show / Hide 
Range on Protein: 875-903
Range on HMM: 1-29/34
Sequence Identity: 27% (8 aa)

PDAYRMLGDCFYQKDDRQQAEFYLRKTIE
..|.  || |.|.. . ..|. ...| .|
AEAWYNLGNCYYKMGNYDEAIECYQKALE
TPR 23053.AA TPR 875-908 26 0.064965 11.02 SMART 1-34 (34) Show / Hide 
Range on Protein: 875-908
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PDAYRMLGDCFYQKDDRQQAEFYLRKTIEFSKIG
..|.  || |.|.. | ..|. ...| .|     
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 23053.AA TPR_1 861-874 50 45.293149 0.74 Pfam 21-34 (34) Show / Hide 
Range on Protein: 861-874
Range on HMM: 21-34/34
Sequence Identity: 50% (7 aa)

IKYLKTALELNTNL
|.... ||||| | 
IECYQKALELNPNN
TPR_2 23053.AA TPR_2 861-874 42 50.705023 0.62 Pfam 21-34 (34) Show / Hide 
Range on Protein: 861-874
Range on HMM: 21-34/34
Sequence Identity: 42% (6 aa)

IKYLKTALELNTNL
|.|.. ||.|. | 
IEYYEKALKLDPNN
TPR_1 23053.AA TPR_1 910-943 41 7.3e-08 31.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 910-943
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

EKAYYQLGQIKTDQEKLDECIYFYRKCLEFNPNH
 .|.|.||..   ....|| | .|.|.|| |||.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 23053.AA TPR 910-943 38 3.1e-07 31.28 SMART 1-34 (34) Show / Hide 
Range on Protein: 910-943
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

EKAYYQLGQIKTDQEKLDECIYFYRKCLEFNPNH
 .|.|.||..   ....||.| .|.|.|| .||.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 23053.AA TPR_2 910-943 41 6e-06 25.08 Pfam 1-34 (34) Show / Hide 
Range on Protein: 910-943
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

EKAYYQLGQIKTDQEKLDECIYFYRKCLEFNPNH
 .|.|.|||.   |...|| | .|.|.|. .||.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_ASK_2 23053.AA TPR_ASK_2 921-943 46 0.00037 11.57 In-house 21-46 (46) Show / Hide 
Range on Protein: 921-943
Range on HMM: 21-46/46
Sequence Identity: 46% (12 aa)

TD---QEKLDECIYFYRKCLEFNPNH
||    | .|. |. |||  | .|||
TDEAARESRDQAIHWYRKGFEIQPNH