Gene 12283 (Tetrahymena)

12283

Species: Tetrahymena
Alias: 1093, 151.m00096, TTHERM_00856580, PreTt12283, 12283
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A2

Sequence

Name Sequence Type Origin Length Description Download
12283.AA Protein None 604 None Fasta, JSON
12283.kin_dom Protein Kinase Domain None 208 None Fasta, JSON
12283.NA RNA None 1815 None Fasta, JSON

Protein domain

Protein domains of 12283.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 12283.AA Ciliate-A2 37-298 43 5.2e-138 464.79 In-house 1-272 (272) Show / Hide 
Range on Protein: 37-298
Range on HMM: 1-272/272
Sequence Identity: 43% (121 aa)

GEGSYANVILIREF--FN--EYALKIIPLDDGFGK-VCPIKLREAKEEAKKLSNCNHINIIRYHKEFQLGNYYFIQVEKC-EMSLYDWIK--QNQDKKIQ
|.|....||.....  .|  .||.||....||... ....||.|.|.||..|.||||.||..||.|||.|.|||||.||| |.||.|||.  |||.|.|.
GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP

RQIFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQ-IKLCDFGLVKDAN-IIKDQNFQISSIKGAPLYFPPEIINKDNISSCLESVDGIQYQGRV
...|..||.|||.|.||||....|||||||.|||.||..| ||||||||.|... .|..|.|..|..||...|.|||....     |.|...........
DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQ-----CFEMNGEQNKKQQI

MQNKQGDVWAFGICLYQLAGASFKDVASLS----FGNEQYKHQKLVDDDINGVISKILDKFQFKRP-SVKELIEIFE
.|...||.||||||||||.||... . .|     ....||.  ...|. .|  |..|| .  .||| |...... ..
KQTFMGDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 12283.AA Ciliate-E6 80-238 37 3.9e-48 151.22 In-house 1-154 (154) Show / Hide 
Range on Protein: 80-238
Range on HMM: 1-154/154
Sequence Identity: 37% (61 aa)

AKKLSNCNHINIIRYHKEFQLGNYYFIQVEKCEMSLYDWIKQNQDKKIQRQI--FLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQIKLCDFGLV
.. | ||||.||..|  .||  |||||..|.|||.|.|||.|...||.. |   |.||..|.. |||||||   ||  ..|||| ||. . ||.||||. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KDANIIKDQ-NFQISSIKGAPLYFPPEIINKDNISSCLESVDGIQYQGRVMQNKQGDVWAFG
.  .       |...       |.|||  .  . .. ...         | . . || |  .
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHY--------KVNWTQEGDIWSVC
S_TKc 12283.AA S_TKc 30-297 22 3.6e-28 100.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 30-297
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

EIINLQAGEGSYANVILIREFF--NEYALKIIPLDDGFGKVCPIKLREAKEEAKKLSNCNHINIIRYHKEFQLGNYYFIQVEKCEM---SLYDWIKQNQD
  |  . |.|... | . |.     ..|.|||.             . .. | . |.. .| ||....  ||  .....  | |.    .|.| ||... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

KK----IQRQIFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQIKLCDFGLVKDANIIKDQNFQISSIKGAPLYFPPEIINKDNISSCLESVDGI
..    .      ... ||. |.||.||. .. |||   |||||.  .||.||||| .            ... | | | .||..               
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---------------

QYQGRVMQNK-QGDVWAFGICLYQLAG--ASFKDVASLSFGNEQYKHQKLVDDDINGVISKILDKFQFKRPSVKELIE---------IF
        .|   |.|..|..|| ..     |         .. .|. .  ...    |.|.|.|   |||.. |. .          |
------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 12283.AA Ciliate-E2-Unclassified 30-244 21 1.3e-24 82.27 In-house 1-263 (352) Show / Hide 
Range on Protein: 30-244
Range on HMM: 1-263/352
Sequence Identity: 21% (61 aa)

EIINLQAGEGSYANVILIRE------FFNEYALKIIPLDDGFG-KVCPIKLREAKEEAKK---------------LSNCNHINIIRYHKEFQLGNYYFIQ
 .|. | |.|... | . ..      .. .|. ||.  ..    ..  ....|.||. .|               |.|..|..|.... .||  .. .| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

VEKCEM-SLYDWIKQ---------------NQDKKIQRQIFL-----KFALQILYAVEYLHSRE-FVLRDLSLKNILLDQFQ---QIKLCDFGLVK--DA
 |.||  .| ..||.               .|.|... |  .     ... ||| . ||||.   .. ||. . |||.|. .   .||..|||. |  . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

NIIKDQNFQ-----------ISSIKGAPLYF----PPEIINKDNIS---SCLESVDGIQYQGRVMQNKQGDVWAFGICLYQL
|. .| ..|           .... | | |     .||.. . | .   .                 .. |.|..|..||..
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-----------------YKCDIWSLGVILYEM
Kinase 12283.AA Ciliate-E2 30-244 20 8.7e-23 75.03 In-house 1-289 (365) Show / Hide 
Range on Protein: 30-244
Range on HMM: 1-289/365
Sequence Identity: 20% (64 aa)

EIINLQAGEGSYA-----NVILIREFF--------------------NEYALKIIPLDDGFGKVCPIK-LREAK------EEAKKLSNCNHINIIRYHKE
 ... . |.|...     .|.. .. |                    ..||.||.  .. . .   |. .|| .      .| . |.. || |||...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--LGNYYFIQVEKCEM-SLYDWIKQN----------QDKKIQRQIFLKFALQILY---------------AVEYLHSRE-FVLRDLSLKNILLDQFQQ
||    |....  | |.  .|.|.||.|          . |..  .  ...  |||.               |.|||||.   . ||. . |||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLCDFGLVKDAN-------------IIKDQN----------------FQISSIKGAPLYFPPEIINKDNISSCLESVDGIQYQGRVMQNKQGDVWAFGI
||..|||| |...             .... .                ... .| | | | .|||.|. ...           |..   ... |.|..|.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---------QKQKGYDYKCDIWSLGV

CLYQL
.||..
ILYEM
Kinase 12283.AA Pkinase 37-297 20 1.6e-22 80.71 Pfam 8-293 (293) Show / Hide 
Range on Protein: 37-297
Range on HMM: 8-293/293
Sequence Identity: 20% (65 aa)

GEGSYANVILIREFFNE--YALKIIPLDDGFGKVCPIKLREAKEEAKKLSNCNHINIIRYHKEFQLGNYYFIQVEKCEM-----SLYDWIKQNQDKKI--
|.||.. | . ..  ..  .|.|||... .  . ... .| .  |.. . ..|| ||.|..  |. .... .  | ||.     .|.|.|.  .....  
GSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

QRQIFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQI----KLCDFGLVKDANIIKDQNFQISSIKGAPLYFPPEIINKDNISSCLESVDGIQYQ
. .   ....||| ..||.||. .. ||| . |||.|.  .|    |.||||| | ..     |   ... | | | .||.|.                 
SEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIR-----------------

GRVMQNKQGDVWAFGICLYQLAGASFKDVASLSFGNE--------QYKHQKLVD-------------------------------DDINGVISKILDKFQ
|. .  .  |.|..|. ||...         . | ..        ......  .                               ..   .|...|.|  
GGQYYGPKVDMWSCGCILYEMLCGR------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

FKRPSVKELIEI--F
 |||. ... .   |
KKRPTAEQILQHPWF
Kinase 12283.AA TKL 114-245 20 1.1e-20 71.18 In-house 124-283 (364) Show / Hide 
Range on Protein: 114-245
Range on HMM: 124-283/364
Sequence Identity: 20% (35 aa)

SLYDWIKQNQDKKIQRQIFLKFALQILYAVEYLHSRE--------FVLRDLSLKNILLDQFQQ--------------IKLCDFGLVKDANIIKDQNFQIS
||.. .          . ....||.|  ...||||..         . |||  ||||.|.  .              .|.||||| .. .  ...| . .
SLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMT

S----------------IKGAPLYFPPEIINKDNISSCLESVDGIQYQGRVMQNKQGDVWAFGICLYQLA
.                . | | . .||......  ..  ..|. . ..    ... ||..|||.|. ..
TMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-F-CKGFEYSEKCDVYSFGIVLWEIL
Kinase 12283.AA AGC 138-244 21 1.3e-20 48.56 In-house 161-298 (395) Show / Hide 
Range on Protein: 138-244
Range on HMM: 161-298/395
Sequence Identity: 21% (34 aa)

QILYAVEYLHS-REFVLRD-LSLKNILLDQFQQIKLCDFGLVKDANI------------------------------------------------IKDQN
.|. |.||||| . .. || | . |||||.   |||.|||| |  .                                                 . ...
CIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKR

FQISSIKG--APLYFPPEIINKDNISSCLESVDGIQYQGRVMQNKQGDVWA--FGICLYQL
.. ... |   | | .|||.                       .|. | |.  .|...|..
DRTWTFCGPCTPEYMAPEIL----------------------YGKACDWWSFGLGCLMYEM
Kinase 12283.AA CAMK 35-207 16 6.9e-19 56.84 In-house 1-294 (425) Show / Hide 
Range on Protein: 35-207
Range on HMM: 1-294/425
Sequence Identity: 16% (49 aa)

QAGEGSYANVILIRE-FFNE-------------YALKIIPLD----------------DGFGKVC------PIKLREAKEEAKKLSNCN-------HINI
. |.||.. | | ..   .              .| |||. .                |  .. .      | .... . | . .....       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRYHKEFQ------------LGNY--------YFIQV---EKC---EM--SLYDWIKQNQD-------------KKIQRQIFLKFALQILYAVEYLHSRE
|. .  ..              ..        ...     | |   |.   |.|.|... .             .... .   ..  ||. ||.|.||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FVLRDLSLKNILLDQFQ-----------------QIKLCDFGLVKDANIIKDQNF--------------------QISSIKGAPLYFP-PEIINK
 | ||| . |||||.                   .||..|||. .  .  .....                      .   | | | . ||..|.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG
Kinase 12283.AA TKL-Unique 114-242 26 2.2e-16 54.41 In-house 86-219 (290) Show / Hide 
Range on Protein: 114-242
Range on HMM: 86-219/290
Sequence Identity: 26% (39 aa)

SLYDWIKQ--------NQDKKIQRQIFLKFALQILYAVEYLHSRE--FVLRDLSLKNILLDQF-----QQIKLCDFGLVKDANIIKDQNFQIS------S
|||| . |        |. .|.  | ..|.|..|  . .|||..|     |||  .|.|.|..      .||.|||||.| .. | . ..  .      .
SLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQT

IKGAPLYFPPEIINKDNISSCLESVDGIQYQGRVMQNKQGDVWAFGICLY
 .| ... .||...  .                 . ... ||..|||.|.
RCGSFRWMAPEVLRMNF----------------CQYSEKSDVYSFGIVLW
Kinase 12283.AA Ciliate-C7 35-194 24 2.4e-15 46.1 In-house 3-164 (164) Show / Hide 
Range on Protein: 35-194
Range on HMM: 3-164/164
Sequence Identity: 24% (40 aa)

QAGEGSYANVILIREFFNE--YALKIIPLDDGFGKVCPIKLREAKEEAKKLSNCNHI-NIIRYHKEFQLGNYYFIQVEKCEM-SLYDWIKQNQDKKIQRQ
..|.|..  |.| ..  ..  || | .   |  |..    . ... |.. |..|  . . ..  ..|   ...... . |   .| . |..||.|.    
FLGQGQQGLVLLAKDQKTNMRYAIKGVQVRDKQGNIDQDINNQVQQEINILKQCKDSPYVVCLLHQFEGQQFIYLVLNECQGGTLNQIIERNQNKRLNEI

IFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQIKLCDFGLVKDANIIKDQNFQISSIK
 ..|.|  |     | ||...|..||.. ||| |.    ..|||||   .|... .. ||..  
SAIKYAKDIAQGLYYIHSKNCVVNDLKMDNILIDYNGNAVVCDFGLA--DNLTQKSKYQINQYM
Kinase 12283.AA PEK 105-207 17 6.4e-14 44.14 In-house 359-563 (655) Show / Hide 
Range on Protein: 105-207
Range on HMM: 359-563/655
Sequence Identity: 17% (35 aa)

FIQVEKCE-MSLYDWIKQN------------------------------------------QDKKIQRQIFLKFALQILYAVEYLHSREFVLRDLSLKNI
.|| | ||  .| |||..|                                            ......  .... ||| ...|.||. .. |||  .||
YIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNI

LLDQFQQ-----IKLCDFGLVK-----------------------DANIIKDQNFQIS----SIK---------------------------GAPLYFPP
.||. .|     .|  ||||..                        ..  ...|.. .    ...                           | .|| .|
FLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMSP

EIINK
| ...
EQLSG
Kinase 12283.AA Pkinase_Tyr 114-179 30 2e-10 35.94 Pfam 93-160 (270) Show / Hide 
Range on Protein: 114-179
Range on HMM: 93-160/270
Sequence Identity: 30% (21 aa)

SLYDWIKQN--QDKKIQRQIFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQIKLCDFGLVKD
.|.|  ...  .....  .  |....||  . |||.|. .. |||  .|.|..   ..| ||||| .|
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD
Kinase 12283.AA TyrKc 30-297 19 5.9e-10 -61.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 30-297
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

EIINLQAGEGSYANVILIREFFNEYALKIIPLDDGFGKVCPIKLREAKEEAKKLSNC--NHINIIRYHKEFQLG-------NYYFIQVEKCEM-SLYDWI
   . . ||| .  | . .    . | | .  |          ...  .||. ...   .| ||.| .     .         ..| .| ..  .| | .
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KQNQDKKIQRQIFLKFALQILYAVEYLHSREFVLRDLSLKNILLDQFQQIKLCDFGLVKDANII------KDQNFQIS--SIKG-APL-YFPPEIINKDN
. ...| .. . .|.|..||    |||||. .. |||   |.|..  ...| .|||| .|          ||   . .  . |.  |.   .|| | ...
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

ISSCLESVDGIQYQGRVMQNKQGDVWAFGICLY--------QLAG-----ASFKDVASLSFGNEQYKHQKL--------VDDDINGVISKILDKFQFKRP
. .                  . |||.||.|..           |      | ..|  .    .  .  .           |..  ....  .    .||
KFT-----------------TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP

SVKELIEIF
. .|..|.|
TFSEIHECF
Kinase 12283.AA PEK 72-95 48 0.003296 6.16 In-house 56-80 (655) Show / Hide 
Range on Protein: 72-95
Range on HMM: 56-80/655
Sequence Identity: 48% (12 aa)

KLRE-AKEEAKKLSNCNHINIIRYH
|..| .  |.| |. .||.||.|||
KHCEKVLREVKTLARLNHPNIVRYH
Kinase 12283.AA Pkinase_Tyr 233-242 50 0.347143 4.64 Pfam 196-205 (270) Show / Hide 
Range on Protein: 233-242
Range on HMM: 196-205/270
Sequence Identity: 50% (5 aa)

DVWAFGICLY
|||.||....
DVWSFGVLMW
TPR_1 12283.AA TPR_1 486-519 47 3.2e-08 32.7 Pfam 1-34 (34) Show / Hide 
Range on Protein: 486-519
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

EELYYYVGFALIQLQKYDESIEYLIKALELNPNY
 | .|  | .. ....||| ||.. ||||||||.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 12283.AA TPR_2 486-519 44 7.7e-08 31.82 Pfam 1-34 (34) Show / Hide 
Range on Protein: 486-519
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

EELYYYVGFALIQLQKYDESIEYLIKALELNPNY
 |..|. | .......||| |||. |||.|.||.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 12283.AA TPR_1 384-417 35 2.4e-07 29.65 Pfam 1-34 (34) Show / Hide 
Range on Protein: 384-417
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

EQALYQLGVEYNKLQEYQLATQCFLQLIQINPQN
 .|.|.||. | |...|. | .|. . ...||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 12283.AA TPR 486-519 44 4.4e-07 30.77 SMART 1-34 (34) Show / Hide 
Range on Protein: 486-519
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

EELYYYVGFALIQLQKYDESIEYLIKALELNPNY
 | .|  | .. .. .||| ||.. |||||.||.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 12283.AA TPR_1 520-553 41 5.8e-07 28.29 Pfam 1-34 (34) Show / Hide 
Range on Protein: 520-553
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DQAYQQLAYIFNIKQKYDQAIQFSQKAIEINPNN
 .|. .|....  ...||.||.. |||.|.||||
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 12283.AA TPR 384-417 32 9.6e-07 29.65 SMART 1-34 (34) Show / Hide 
Range on Protein: 384-417
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

EQALYQLGVEYNKLQEYQLATQCFLQLIQINPQN
 .|.|.||. | |. .|. | .|. . ....|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 12283.AA TPR 520-553 38 5e-06 27.39 SMART 1-34 (34) Show / Hide 
Range on Protein: 520-553
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DQAYQQLAYIFNIKQKYDQAIQFSQKAIEINPNN
 .|. .|. ..  . .||.||.. |||.|..|||
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
Kinase 12283.AA TPR_1 554-587 41 8e-06 24.37 Pfam 1-34 (34) Show / Hide 
Range on Protein: 554-587
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

DSVYYQLGWAYEKSYLTPLAIDSYKKSLQINPNN
  ..|.||..|.|      ||. |.| |..||||
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 12283.AA TPR 554-587 38 1.7e-05 25.5 SMART 1-34 (34) Show / Hide 
Range on Protein: 554-587
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DSVYYQLGWAYEKSYLTPLAIDSYKKSLQINPNN
  ..|.|| .|.|      ||. |.|.|...|||
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 12283.AA TPR_1 452-485 32 0.000106 20.39 Pfam 1-34 (34) Show / Hide 
Range on Protein: 452-485
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

YIGYYELAYTFYFQQMYNESIECLQQAIMYNQQS
.  .| |....| .. |.| |||.|.|.  | . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
Kinase 12283.AA TPR_2 554-587 38 0.000127 20.44 Pfam 1-34 (34) Show / Hide 
Range on Protein: 554-587
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

DSVYYQLGWAYEKSYLTPLAIDSYKKSLQINPNN
  ..|.||..|.|      ||. |.|.|...|||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 12283.AA TPR_2 384-417 29 0.000134 20.36 Pfam 1-34 (34) Show / Hide 
Range on Protein: 384-417
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

EQALYQLGVEYNKLQEYQLATQCFLQLIQINPQN
  |.|.||. | |...|. | ... ......|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 12283.AA TPR 452-485 29 0.000631 20.29 SMART 1-34 (34) Show / Hide 
Range on Protein: 452-485
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

YIGYYELAYTFYFQQMYNESIECLQQAIMYNQQS
.  .| |.  .| .  |.| |||.|.|.  . . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 12283.AA TPR_2 452-485 26 0.001186 17.01 Pfam 1-34 (34) Show / Hide 
Range on Protein: 452-485
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

YIGYYELAYTFYFQQMYNESIECLQQAIMYNQQS
  ..| |.   | |. | | ||....|. .. . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 12283.AA TPR_2 520-553 32 0.004082 15.11 Pfam 1-34 (34) Show / Hide 
Range on Protein: 520-553
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

DQAYQQLAYIFNIKQKYDQAIQFSQKAIEINPNN
  |. .|. .   ...||.||.. .||....|||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
Kinase 12283.AA Ciliate-E2-Unclassified 569-600 30 0.025503 3.88 In-house 317-352 (352) Show / Hide 
Range on Protein: 569-600
Range on HMM: 317-352/352
Sequence Identity: 30% (11 aa)

LTPLAIDSYK----KSLQINPNNKDSAEQLNQLQFF
. | |.|  .    | |. |||.. ..||. . ..|
WSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 12283.AA Ciliate-E2 530-600 19 0.0357 3.24 In-house 296-365 (365) Show / Hide 
Range on Protein: 530-600
Range on HMM: 296-365/365
Sequence Identity: 19% (15 aa)

FNIKQKYDQAIQFSQKAIEINPNNDSVYYQLGWAYEK--SYLTPLAIDSYKK----SLQINPNNKDS-AEQLNQLQFF
| ..|. .. |.|...  . .  .  .   ..|   |   .... ..|  ||     || .|..  . .||. . ..|
F-QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKW---KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
TPR_1 12283.AA TPR_1 370-383 50 0.0745 10.46 Pfam 21-34 (34) Show / Hide 
Range on Protein: 370-383
Range on HMM: 21-34/34
Sequence Identity: 50% (7 aa)

IECYKNSIKINPKN
||||.  ...||.|
IECYQKALELNPNN
TPR 12283.AA TPR 418-451 29 0.100366 9.36 SMART 1-34 (34) Show / Hide 
Range on Protein: 418-451
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

YDAHVQITHAYNRMKLYTEAYNLGMVAIQLNPQN
..|. .. ..| .|. | || .    |..|.|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 12283.AA TPR_2 370-383 42 2.789108 5.08 Pfam 21-34 (34) Show / Hide 
Range on Protein: 370-383
Range on HMM: 21-34/34
Sequence Identity: 42% (6 aa)

IECYKNSIKINPKN
||.|. ..|..|.|
IEYYEKALKLDPNN
TPR_1 12283.AA TPR_1 418-451 32 6.106786 3.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 418-451
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

YDAHVQITHAYNRMKLYTEAYNLGMVAIQLNPQN
..|. .. ..| .|. | ||      |..|||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 12283.AA TPR_2 444-451 50 72.458728 0.07 Pfam 27-34 (34) Show / Hide 
Range on Protein: 444-451
Range on HMM: 27-34/34
Sequence Identity: 50% (4 aa)

AIQLNPQN
|..|.|.|
ALKLDPNN