Gene 13287 (Tetrahymena)
13287
Sequence
Protein domains of 13287.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 13287.AA | Aur | 97-349 | 48 | 1.5e-210 | 562.22 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 97-349 Range on HMM: 1-257/257 Sequence Identity: 48% (125 aa) WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQRGNLFSVLKKA--NKMDE . . ..|| |..| |.||..|.|. .||.|.|.|.||.|.|....|.||||||... ||||.|...||.|.|..||.||||..|.|...|.|. ...|| FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE SVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQ-GNNIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYDHRIDIWSLGVLLFELVHGYAP |..|.||.|.|.|..|...|||||.||||.|.|| .|||.||||||... ||..|.|||||.|||.||||.. ..||..|||.||||..||.||..| QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP FQG-NNQNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM |.. .|.....|.|... ||| ... ....|||..||| .|..|.|..||. |||. FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI |
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| Kinase | 13287.AA | AGC | 103-349 | 24 | 7.69999999999e-106 | 274.07 | In-house | 7-395 (395) | Show / Hide |
Range on Protein: 103-349 Range on HMM: 7-395/395 Sequence Identity: 24% (98 aa) LGAGSYGVVRLAYDK------YTKERFAIKIMQKSQ-IFKFC--TIDNLKRE------------IKIQKRMV----------HPNICK-LFHYFEDKQN- .| ||.| |.|. .| |.. .|.|...|. | . .... ..| .| ... ||.|.| |.. |.||.. IGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHT -VYLVLEYAQ---------RG-NLFSVLK---KANKMDESVAFWYFYQ-------TCLAIDHLHH-NQIIHRD-LKPENLLVDQGNNIKVCDFGWSAENS .|.|.||.. | ||. |. | ..||..| |. . ..||...|| . ||||| |||||.| |. .|| .||| . |. YLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGM NN---------------------------------------------------QIRTTFCG--TVDYMAPEMVKRSTYDHRIDIWS--LGVLLFELVHGY |. . .|||| | .|||||.. |.. |.|| ||.|..|.. || NDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGY APFQGNN----------QNQKLDNISK-----NKPIQFR----------PNLEFDLVDLIKNILQPNPEYRLT----------MAQIFDHPWM ||.|.| .... ..| . |....| ... ...|||| |...|| ||. .| .||| PPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 13287.AA | MARK | 97-349 | 39 | 1.6e-102 | 335.92 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 97-349
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)
WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFE--DKQN-VYLVLEYAQRGNLFSVLKKA--NK
..| |||..|.|| .| |....||||..| ........ |..|||.| |.. |||| ||||..| ..|. .||..||| .|.|.. .|.. .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR
MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGN--NIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYD-HRIDIWSLGVLLFELV
. |. | .| | . |. .| . |.|||.||||.|.|. . ||| .|||.|.. ..| .||||| |||||.... || .|||||||.|. .|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV
HGYAPFQGNN--QNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM
.|| || | . ... .| . |. . ... .. .||. .|..|||.| |. .| ||||
CGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
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| Kinase | 13287.AA | CAMKL | 95-349 | 36 | 2.3e-102 | 327.52 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 95-349 Range on HMM: 1-297/297 Sequence Identity: 36% (109 aa) YEWANPGQLGAGSYGVVRLAYD-KYTKERFAIKIMQKSQIF-KFCTIDN-----------LKREIKIQKRMV---HPNICKLFHYFEDKQN------VYL |. .|| ||.|.|.|| . ..|.|. ||||. |. | . .. .| ..|||.|.|.. ||||.||.. .|.... .|| YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL VLEYAQRGN--LFSVLKKA----NKMDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVD-QGN-NIKVCDFGWSAE-----NSNNQIRTTFCGTVD |.||.. |. || ..| .|.|. | || | . |....| . |.|||.||||.|.| .|| |||..||| |.. . ..| .||||. VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP YMAPEMVKR--STYD-HRIDIWSLGVLLFELVHGYAPFQ-------GNNQNQKLDNISKNKPIQFR--PNLEFDLVDLIKNILQPNPEYRLTMAQIFDHP |||||.... || .||||.||.|. .| || || |.. . .| .. . ... . . |. |||. .||.|||.| |. || || YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP WM || WM |
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| Kinase | 13287.AA | CAMK | 102-349 | 24 | 1.9e-97 | 314.53 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 102-349
Range on HMM: 1-425/425
Sequence Identity: 24% (103 aa)
QLGAGSYGVVRLAYDKYTK------------ERFAIKIMQKSQIFKFC-------------------------TIDNLKREIKIQKRMV-------HPNI
.|| ||.|.|.|...| |. ...||||. |... . . . .|..|||.| |.. ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
CKLFHYFED-------------------KQNVYLVL---EYAQRG----NLFSVLKKANK---------------MDESVAFWYFYQTCLAIDHLHHNQI
.||....|| ....|.|. ||.. | ||. ... . ..|. | || | | |....| . |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDLKPENLLVDQG-----------------NNIKVCDFGWS--AENSN----------------------NQIRTTFCGTVDYMA-PEMVKRST----
.||||||||.|.|. ||||..||| . . .. .| .||||| ||| ||......
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YDHRIDIWSLGVLLFELVHGYAPFQGNNQNQKLD------NIS----KNKPIQFR-PNLEFD-------------------------LVD
|. .|.||.||.|. .. || ||.| ..|. .. |.. | . ... | .|. |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LIKNILQPNPEYRLTMAQIFDHPWM
||...||..|| |.| .|. .||||
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 13287.AA | S_TKc | 97-349 | 34 | 4.4e-97 | 329.74 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 97-349 Range on HMM: 1-231/231 Sequence Identity: 34% (92 aa) WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQR--GNLFSVLKKANK--- . ..| |..|.|.....| |....||||. ....|||.| |. ||||.||. .|.| ...|.|.||. |.||...|| .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYDH-RIDIWSLGVLLFEL ..| .| |.||.|.|....| ..||||||||||.|.|. .||.|||| ... |||||| .|||||.. |.. ..|.||.|..|.|. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM VHGYAPFQGNNQNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFD-------HPWM . || ||. .... ...| .. |.|...|| .|| |.| ... |||. LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 13287.AA | Pkinase | 97-349 | 32 | 2.4e-93 | 321.19 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 97-349 Range on HMM: 1-293/293 Sequence Identity: 32% (96 aa) WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLK-REIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQRG----NLFSVLK--KA . ...|.||.|.|.....| | ...|.||. |. . . . . ... .||.| ||. ||||..|...||||...|.|.||.. | ||.... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH NKM--DESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNI----KVCDFGWSAE--NSNNQIRTTFCGTVDYMAPEMVK-RSTYDHRIDIWSL ... .| .. |.||.. .....| . ||||||||||.|.|. ..| |.|||| .. . ||. |||||| .||||| .. .. |....|.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLLFELVHGYAPFQGN------NQNQKLDNISKNKPIQFRP--------------------NLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM |..|.|.. |. ||.| .|.|....| . .. .| |.. .. |.||..|...|. |.| .||. |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 13287.AA | Ciliate-E2-Unclassified | 102-349 | 31 | 4.5e-81 | 275.66 | In-house | 6-352 (352) | Show / Hide |
Range on Protein: 102-349
Range on HMM: 6-352/352
Sequence Identity: 31% (111 aa)
QLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTI---DNLKREIKIQKRMV-------------------HPNICKLFHYFEDKQNVYLVLEYAQR
|.| |..|.|.....| .|. .|.|.| |.||.| . | |....|.|. ... ||.| |.|..|.||||.|.|.||..
QIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEG
GNLFSVLKKANK-----------------MDESVAF-----WYFYQTCLAIDHLHHNQ-IIHRDLKPENLLVDQGN---NIKVCDFGWSAENSNN-----
|.|. .|| .| .| | ||.| ......|||.. |||||.||||.|.|... .||..||| | .. .|
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDT
-----------QIRTTFCGTVDYM----APEMVKRSTYDHR----IDIWSLGVLLFELVHGYAPFQGNNQNQ---------------KLDNISKNKPIQF
|. .||||| || |||. .. |||. .|||||||.|.|.. || ||..||..| | .. |.|.|||
NQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQF
RP--------NLEFDLVDLIK----NILQPNPEYRLTMAQIFDHPWM
.. .. . |.|. .|. ||..|.|. ||. |||.
PKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 13287.AA | Ciliate-E2 | 102-349 | 25 | 1.4e-78 | 267.35 | In-house | 6-365 (365) | Show / Hide |
Range on Protein: 102-349
Range on HMM: 6-365/365
Sequence Identity: 25% (96 aa)
QLGAGSYGVVRLAYDKYTKERFA-----------------------IKIMQKSQIFKFCTIDNLKREIK----------IQKRMVHPNICKLFHYFE--D
..| |..|.|... .. ....|| .|||.|.||. . .... |||. |.... ||||.|.. .|. |
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD
KQNVYLVLEYAQRGNLFSVLK------------KANKMDESVAFWYFYQTCL---------------AIDHLHHNQ-IIHRDLKPENLLVDQGNNIKVCD
..|.|||.||.| |.||. .| . ....| . ...| . |. .|| . |||||.||||.|. ||..|
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIID
FGWSAENSNNQIRTT--------------------------------FCGTVDYMAPEMVKRST---------YDHRIDIWSLGVLLFELVHGYAPFQGN
|| | .........| .||| |||||.... ||. .|||||||.|.|.. |. ||
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---
NQNQKLDNISKNKPIQFRPNL-------------EF-----DLVDLIKN----ILQPNPEYRLT-MAQIFDHPWM
.. |...|.|... .. . ||||. .|| .|| |.| . ||..|||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 13287.AA | RSK | 97-349 | 34 | 2.9e-77 | 262.98 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 97-349
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)
WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCT-IDNLKREIKIQKRMV-HPNICKLFHYFEDKQNVYLVLEYAQRGNLFSVLKKANK---
||.| |.. ..| .. |. .| |. .|. | . . . ..|..| .| ||.|..|.. |.... .||..|| | || |.|
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC
MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQ---GNNIKVCDFGWSAE--NSNNQIRTTFCGTVDYMAPEMVK----RSTYDHRIDIWSLGV
..|. | |... ||..||| .|||||||||| | |. ||..||| . . ...|| |||.|..||||||.| ....|. |.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV
LLFELVHGYAPFQG---NNQNQKLDNISKNK-PIQFR--PNLEFDLVDLIKNILQPNPEYRLT-----MAQIFDHPWM
|..|. |. |||| ||... ...| |.| . ..| . |||. |. .|. ||. ...| .|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
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| Kinase | 13287.AA | ULK | 97-349 | 28 | 1.7e-74 | 253.79 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 97-349 Range on HMM: 1-329/329 Sequence Identity: 28% (93 aa) WANPGQLGAGSYGVVRLAYDKYTK----ERFAIKIMQ---KSQIFKFCT----IDNLKREIKIQKRMV--------HPNICKLFHYFEDK--QNVYLVLE . .|| ||.|.| ...| || | .|.|... ..|. . . .. ||.||||.|.. ||||.||...||.. |.|...| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YAQRGNLFSVLKKANKMDESV----------AFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNN------------IKVCDFGWSAENSNN----Q | . |.|.. .|| .|. |.. | .|.| . . .|| ..|||||.||.| |.. |. .|..||| . .|. | YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ IRTTFC------GTVDYMAPEMVK----RSTYD-HRIDIWSLGVLLFELVHGYAPFQGNNQNQKL-----DNISK---------NKPIQFR-----PNLE . .|. || ||||. .. . |. . ||||||....|.. |. ||... |. ..| . ..|.||. |.. MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS FDLVDLIKNILQPNPEYRLTMAQIFDHPWM .. |||. || ... | . ..|.|||. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 13287.AA | ULK | 97-349 | 29 | 6.5e-74 | 251.87 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 97-349 Range on HMM: 1-324/324 Sequence Identity: 29% (96 aa) WANPGQLGAGSYG-VVRLAYDKYT---KERFAIKIMQKSQIFKFCT-------IDNLKREIKIQKRMV---HPN--ICKLFHYFEDK--QNVYLVLEYAQ . .|| ||.| .| ...| | .. .|.|...|... |. ...||.||.|.| . ||| |.||...||.. |.|...|| . YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN RGNLFSVLKKANK---------MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNN------------IKVCDFGWSAE-NSNN---QIRTT |.|.. .|| .| |. | .|.| | . .|| ..|||||.||.|.|. |. .|..||| . ..|| |...| GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT FC------GTVDYMAPEMVK----RSTYD-HRIDIWSLGVLLFELVHGYAPFQGNNQNQKL----DNISK---------NKPIQFR-----PNLEFDLVD .. || ||||. .. . |. . ||||||....|.. |. ||... |. . | . |.||||. |.. .. | CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD LIKNILQPNPEYRLTMAQIFDHPWM ||. || ... | . .||.|||. LIRRMLQYDEKDRISWEEIFNHPWF |
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| Kinase | 13287.AA | TyrKc | 102-349 | 22 | 5.2e-20 | 73.71 | SMART | 6-280 (280) | Show / Hide |
Range on Protein: 102-349 Range on HMM: 6-280/280 Sequence Identity: 22% (63 aa) QLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRM--VHPNICKLFHYFEDK-------QNVYLVLEYAQRGNLFSVLKKANK- .|| | .|.|... | . |.| .... . . ||..| .. |||| .|. . .. . ...|.||. |.| . |.| . KLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFGWSAENSNN--------QIRTTF--CGT----VDYMAPEMVKRSTYDHRIDI . . .| . ..||....||||| | ||. .. .|..||| | . . .|.. .| . |||| . ... . |. LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV WSLGVLLFELV-HGYAPFQG-----NNQNQKLDNISKNKPIQFRPN--------LEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM || ||...|. | | | . . . .. . . || .. ...| . .|| | |...| | . WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 13287.AA | Pkinase_Tyr | 102-240 | 28 | 1.1e-14 | 50.4 | Pfam | 6-156 (270) | Show / Hide |
Range on Protein: 102-240
Range on HMM: 6-156/270
Sequence Identity: 28% (45 aa)
QLGAGSYGVVRLAYDK----YTKERFAIKIMQKSQIFKFCTIDN-----LKREIKIQKRM-VHPNICKLFHYFE-DKQN--VYLVLEYAQRGNLFSVLKK
.||.|..|.|.... | || |.|.. | .. .. . ||.|| | . |||| .| ... .|.|.||.. |.| . |.|
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK
----ANKMDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFG
.. . . . .| . . ..|. ...||||| | ||. .| .|.||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
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| Kinase | 13287.AA | Pkinase_Tyr | 261-296 | 36 | 0.001966 | 12.25 | Pfam | 181-218 (270) | Show / Hide |
Range on Protein: 261-296 Range on HMM: 181-218/270 Sequence Identity: 36% (14 aa) MAPEMVKRSTYDHRIDIWSLGVLLFELVH-GYAP-FQG |||| . . . . |.|| |||..|.. | | ..| MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG |
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