Gene 13285 (Tetrahymena)

13285

Species: Tetrahymena
Alias: 4.m00684, 3707.m00319, 441, PreTt13285, TTHERM_00070950, 13285
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
13285.AA Protein None 456 None Fasta, JSON
13285.NA RNA None 1371 None Fasta, JSON
13285.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 13285.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13285.AA Aur 72-324 47 2.4e-208 556.25 In-house 1-257 (257) Show / Hide 
Range on Protein: 72-324
Range on HMM: 1-257/257
Sequence Identity: 47% (123 aa)

KDKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLKREIKIQKRMNHPNICKLYHYFEDKQYVYLVLEYAEQGSLFHNLRKV--KKFSE
.. .. ||.|..| |.||..|. ....|.|.|.|..|..||....|.||||||...|||||.|.|.||.|.|..||.||||..|.|...|.|.  |.|.|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

ELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDG-KGDIKLCDFGWSAEQRNSIVRKTFCGTVDYMPPEMIENQPHDHRVDIWCLGILLYELIHGYAP
..|....||.|...|..|.. |||||.||||.|.|. .|.||.||||||... |.  |.|||||.|||||||.|.|.|||.|||||||.|.|||.||..|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FLG-HDDQTKLKNIRNRQEIVFEPFVPKDLEELIRGILQHNPLHRLSMDDIFRHRWM
| .  ........|.|. .|.| ....|.. .|| .||||.| .|...|.|..| |.
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 13285.AA AGC 72-324 23 8e-113 292.55 In-house 1-395 (395) Show / Hide 
Range on Protein: 72-324
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

KDKKAFLGQGSYGTVRLAIDK------SDGQKYAIKMMHKST-IFQYC--TIDNLKRE------------IKIQKRMN----------HPNICK-LYHYF
 . .  .|.||.|.|.|. .|      . |. ||.|.. |.. | .    .... ..|             .| ...|          ||.|.| |.. |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDKQY--VYLVLEYAE---------QG-SLFHNLR---KVKKFSEELAFRFFYQ-------TCLGIDHLHK-NSIIHRD-LKPENLLIDGKGDIKLCDFG
.||..  .|.|.||..          |  ||. |.   | ..|.|| |  .. .       ..|....||. . ||||| |||||.|.| .| |||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSAEQRNS---------------------------------------------------IVRKTFCG--TVDYMPPEMIENQPHDHRVDIWC--LGILLY
 . | .|.                                                      .||||  | .||.||..    ... .|.|.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELIHGYAPFLGHDDQ----------TKLKNIRNRQ-----EIVFE----------PFVPKDLEELIRGILQHNPLHRLS----------MDDIFRHRWM
|.. || || |...|           . ..|.|..     .. |           ... ...  ||.. |. .| .||            ..| .| | 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 13285.AA CAMKL 78-324 34 1.6e-99 318.25 In-house 7-297 (297) Show / Hide 
Range on Protein: 78-324
Range on HMM: 7-297/297
Sequence Identity: 34% (102 aa)

LGQGSYGTVRLAID-KSDGQKYAIKMMHKSTIF-QYCTIDN-----------LKREIKIQKRMN---HPNICKLYHYFEDKQY------VYLVLEYAEQG
||.||.|.|.||.. .  |.|.|||...|. |    .. .|           ..|||.|.|..|   ||||.|||. .|....      .|||.||.. |
LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG

S--LFHNLRKV----KKFSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGD--IKLCDFGWSAEQRN-----SIVRKTFCGTVDYMPPEMIE
.  ||. ..|     ....|. | |.| | . .....|.. |.|||.||||.|.| .|.  ||..||| |...|.         |||||.  ||.||...
EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQ

N--QPHD-HRVDIWCLGILLYELIHGYAPFL-------GHDDQTKLKNIRNRQEIVF-EP-FVPKDLEELIRGILQHNPLHRLSMDDIFRHRWM
   .|.|   |||| .|..|| .. || ||        | |.. .|... ...   .  . .|. |.. |||..||.|| .| ....| .|.||
GNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 13285.AA S_TKc 72-324 31 7.6e-98 332.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 72-324
Range on HMM: 1-231/231
Sequence Identity: 31% (86 aa)

KDKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLKREIKIQKRMNHPNICKLYHYFEDKQYVYLVLEYAEQ--GSLFHNLRKVKK---
 ..   .|.|..|.|.....|..|...|||...          ....|||.| |. .||||.||| .|.| ...|.|.||...  |.||. ..| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGDIKLCDFGWSAEQRNSIVRKTFCGTVDYMPPEMIENQPHDH-RVDIWCLGILLYEL
   |.|  | ...||.|......|.. ||||||||||.|.|    ||.|||| ...       .||||| .||.||..   .... ..|.| .|..|||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IHGYAPFLGHDDQTKLKNIRNRQEIVFEPFVPKDLEELIRGILQHNPLHRLSMDDIFR-------HRWM
. || ||   ..|. .|.|.           .... ..||..|| .| .|..  ....       | |.
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13285.AA CAMK 77-324 22 1e-95 308.91 In-house 1-425 (425) Show / Hide 
Range on Protein: 77-324
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)

FLGQGSYGTVRLAIDKSDG------------QKYAIKMMHKSTIF-------------------------QYCTIDNLKREIKIQKR-------MNHPNI
 ||.||.|.|.|.|.|...            ||.|||.. |. .                          . .. .|..|||.| |.       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CKLYHYFED-------------------KQYVYLVL---EYAEQG----SLFHNLRKV---------------KKFSEELAFRFFYQTCLGIDHLHKNSI
.|||...||                   ....|.|.   ||.. |     ||  ...                ..|.|. | |.| | | .....|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENLLIDGK-----------------GDIKLCDFGWSAEQRN------------------------SIVRKTFCGTVDYMP-PEMIEN------
.||||||||.|.| .                 ..||..||| ... .                             ||||||  ||. ||...       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QPHDHRVDIWCLGILLYELIHGYAPFLGH-------------DDQTKLKNIRNRQEIVFEPFVPK-----------------------DLEE
        ....  .|.| .|..|| .  || || |              .|.  ...|.. .    .|....                       .   
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIRGILQHNPLHRLSMDDIFRHRWM
|||..|| .| .|.. ... .| ||
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 13285.AA MARK 78-324 39 1.8e-92 302.59 In-house 7-262 (262) Show / Hide 
Range on Protein: 78-324
Range on HMM: 7-262/262
Sequence Identity: 39% (100 aa)

LGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLKREIKIQKRMNHPNICKLYHYFE--DKQY-VYLVLEYAEQGSLFHNLRKV--KKFSEELA
.|.|||..|.||..|  |.|.|||.. |  ..  ... |..|||.| |...|||| ||.|..|  ..|  .||..|||. |.|.. ....   . .||.|
IGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEA

FRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKG--DIKLCDFGWSAEQRNSIVRKTFCGTVDYMPPEMIENQPHD-HRVDIWCLGILLYELIHGYAPF
 |.| | . ..  .|...|.|||.||||.||| .|  .||..|||.|..  .    .|||||  ||.||... .| |   |||| ||..|| ...|| ||
RRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF

LGHD-DQTKLKNIRNRQEIVFEPFVPKDLEELIRGILQHNPLHRLSMDDIFRHRWM
 | . |. .|.   .| .  . ..|.|... ||. .|..||  | ....| .|.||
DGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 13285.AA Pkinase 72-324 31 1.7e-88 305.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 72-324
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

KDKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLK-REIKIQKRMNHPNICKLYHYFEDKQYVYLVLEYAEQG----SLFHNLR--KV
  ..  .|.||.|.|.....|..|...|.| . |...   . . ... .||.| ||.|||||..||..||||...|.|.||.| |    .||. ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKF--SEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGDI----KLCDFGWSAE--QRNSIVRKTFCGTVDYMPPEMIE-NQPHDHRVDIWCL
..|  ||. . ...||.. |....|...||||||||||.||| .|.|    |.|||| ..     |.   .||||| .||.|| |  .|.....||.| .
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLYELIHGYAPFLGH----DDQTKLKNIRNRQEIVFEPFVP-----------------------KDLEELIRGILQHNPLHRLSMDDIFRHRWM
|..|||.. |. || ||    .  .... |... .  ..   |                       ... ..|...|. .|  |.. ..|. | |.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 13285.AA Ciliate-E2 78-324 23 8.5e-77 261.45 In-house 7-365 (365) Show / Hide 
Range on Protein: 78-324
Range on HMM: 7-365/365
Sequence Identity: 23% (87 aa)

LGQGSYGTVRLAID-----------------------KSDGQKYAIKMMHKSTIFQYCTIDNLKREIK----------IQKRMNHPNICKLYHYFE--DK
.|||..|.|... .                       | ....||.|.|.|. |.|   .... |||.          |....|||||.|.| .|.  |.
IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDD

QYVYLVLEYAEQGSLFHNLRKV-----------KKFSEELAFRFFYQTCL---------------GIDHLHKNS-IIHRDLKPENLLIDGKGDIKLCDFG
...|||.||...|.||. ...            |.|.|. . ....| .                .. .||..  |||||.||||.|.     ||..|||
NNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFG

WSAEQRNSIVRKT--------------------------------FCGTVDYMPPEMIENQP---------HDHRVDIWCLGILLYELIHGYAPFLGHDD
 | .. ..  ..|                                .|||  ||.||......         .|. .|||.||..|||.. |. ||     
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----

QTKLKNIRNRQEIVFEPF-----------------VPKDLEELIRG----ILQHNPLHRLS-MDDIFRHRWM
   ...| . .   ..|.                 ....   ||.     .|| .|  |.. ...|. | |.
---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 13285.AA Ciliate-E2-Unclassified 66-324 27 1.8e-75 257.05 In-house 1-352 (352) Show / Hide 
Range on Protein: 66-324
Range on HMM: 1-352/352
Sequence Identity: 27% (100 aa)

YTFLDQKDKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTI---DNLKREIKIQKRMN-------------------HPNICKLYHYFEDKQ
|... |      .|||..|.|.....|...|.||.|.|.|. |.  . |   |....|.|. ....                   ||.| |....|.|||
YKIIKQ------IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

YVYLVLEYAEQGSLFHNLRKVKK-----------------FSEELAF-----RFFYQTCLGIDHLHKNS-IIHRDLKPENLLIDGKG---DIKLCDFGWS
..|.|.||.|.|.|.  ..| ||                 |.|. |      ..|.| ..|...||..  |||||.||||.|.| .|    ||..||| |
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

AEQRN----------------SIVRKTFCGTVDYM----PPEMIENQPHDHR----VDIWCLGILLYELIHGYAPFLGHDDQT---------------KL
 .. .                .   .|||||  ||    .||....| .||.    .|||.||..|||.. || || . ..                  |
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

KNIRNRQEIVFEPFVP----KDLE--------ELIRGILQHNPLHRLSMDDIFRHRWM
... . ..| | .| .    |..         .|.. .|. ||  |.....|. | |.
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 13285.AA RSK 74-324 33 6.9e-74 251.79 In-house 1-278 (278) Show / Hide 
Range on Protein: 74-324
Range on HMM: 1-278/278
Sequence Identity: 33% (93 aa)

KKAF--LGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCT-IDNLKREIKIQKRMN-HPNICKLYHYFEDKQYVYLVLEYAEQGSLFHNLRKVKK---
 |    .|.|.. ..|  ...  || || |  .|..| |  . .   ..|..| .| . ||.|..|.. |......||..|| . | ||  |.| |    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDG---KGDIKLCDFGWSAEQRNS--IVRKTFCGTVDYMPPEMIE---NQP-HDHRVDIWCLGI
|||. |   ...  | ..|||.  |||||||||| | |     | |||.||| . . |..     .|||.|..||.|||.     |  ||. .|.| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYELIHGYAPFLG---HDDQTKLKNIRNRQ-EIVFE--PFVPKDLEELIRGILQHNPLHRLS-----MDDIFRHRWM
|.||.  |. || |    . .  .|.|.. .    ..  ... ..  .|||. |. .|  ||.     ...| .| |.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 13285.AA ULK 74-324 28 4e-73 249.23 In-house 3-329 (329) Show / Hide 
Range on Protein: 74-324
Range on HMM: 3-329/329
Sequence Identity: 28% (95 aa)

KKAFLGQGSYGTVRLAIDKSD----GQKYAIKMMHKST-IFQY------CTIDNLKREIKIQKRMN--------HPNICKLYHYFEDK--QYVYLVLEYA
..  ||.||.|.|  ...| .    ..|.|.||. |.. . ..        .. ||.||||.|...        ||||.|||..||..   ..|...|| 
LNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYC

EQGSLFHNLRKVKK----------FSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGK------------GDIKLCDFGWSAE-QRN---SIVR
..| |.. . | ||          .||. |  ||.| . |  .|||. |||||.||.| ||. .            | .|..||| .   . .     . 
NGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMM

KTFC------GTVDYMPPEMIENQ-----PHDHRVDIWCLGILLYELIHGYAPFLGHDDQTKL-----KNIRN---------RQEIVFE-----PFVPKD
.|.       ||  || |. ...|     ..|. .||| ||...||.. |. || .   ..       |.|.|          | . |.     | . ..
MTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPE

LEELIRGILQHNPLHRLSMDDIFRHRWM
...|||. || ..  | | ...| | |.
CKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 13285.AA PLK-Unclassified 73-324 31 1.2e-71 244.29 In-house 2-264 (264) Show / Hide 
Range on Protein: 73-324
Range on HMM: 2-264/264
Sequence Identity: 31% (84 aa)

DKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLKREIKIQKRMNHPNICKLYHYFEDKQYVYLVLEYAEQGSLFHNLRKV-------K
 .  ||| |    . .... .  . ||.|   ||..    .   |. ||||.| ..|.|| | .| ||| ..||..||| ..|.|.. ...        |
HRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEKK

KFSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGDIKLCDFGWSAEQRN-SIVRKTFCGTVDYMPPEMIENQP--HDHRVDIWCLGILLYEL
. .|  . .. || . ..  ||.|.|||||||. |......  .|.|||| ..   | .  .||.|||  |  ||  ....  |.  ||.| .|. || |
RLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYTL

IHGYAPFLGHDDQTKLKNIR-NRQEIVFEPFVPKDLEELIRGILQHNPLHRLSMDDIFRHRWM
. |  || ..| .. .|.|. |..    .. ... .  ||. ||. ||  |...| |. | ..
LIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase 13285.AA TyrKc 72-323 21 4.3e-19 70.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 72-323
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

KDKKAFLGQGSYGTVRLAIDKSDGQKYAIKMMHKSTIFQYCTIDNLKREIKIQKRM--NHPNICKLYHYFEDK-------QYVYLVLEYAEQGSLFHNLR
  ..  || | .|.|.... |   .. |.||.....      .  . ||..| ..   .|||| .|| .  ..       . ...|.||.. |.| . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KVKK-FSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGDIKLCDFGWSAEQRNS--------IVRKTF--CGT----VDYMPPEMIENQPHD
| .. .. .    | .| . | ..||.. .|||||   | |.. .. .| .||| | .  .           ||.   .|     .  |.|| |      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

HRVDIWCLGILLYELI-HGYAPFLG-----HDDQTKLKNIRNRQEIVFEPF--------VPKDLEELIRGILQHNPLHRLSMDDIFRHRW
.  |.|  |....|.   |  |  |      ..|  .......      |          |... ....   ...|  | .. .| ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 13285.AA Pkinase_Tyr 69-215 28 1.5e-16 56.69 Pfam 1-156 (270) Show / Hide 
Range on Protein: 69-215
Range on HMM: 1-156/270
Sequence Identity: 28% (45 aa)

LDQKDKKAFLGQGSYGTVRLAIDK----SDGQKYAIKMMHKSTIFQ-YCTIDNLKREIKIQKRM-NHPNICKLYHYFE-DKQY--VYLVLEYAEQGSLFH
.    |   ||.|..|.|.... |    ..... |.||.  ..  .    .. . ||.|| | . .|||| .||     ...   .|.|.||.. |.| .
ITFGKK---LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

NLRK----VKKFSEELAFRFFYQTCLGIDHLHKNSIIHRDLKPENLLIDGKGDIKLCDFG
 |||     .... .    . .| . | ..|. . .|||||   | |.. .. .| ||||
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG