Gene 13234 (Tetrahymena)

13234

Species: Tetrahymena
Alias: 4.m00633, TTHERM_00069440, 446, PreTt13234, 3707.m00269, 13234
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
13234.AA Protein None 630 None Fasta, JSON
13234.kin_dom Protein Kinase Domain None 553 None Fasta, JSON
13234.NA RNA None 1893 None Fasta, JSON

Protein domain

Protein domains of 13234.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13234.AA SRPK 75-627 45 0.0 1068.75 In-house 1-554 (554) Show / Hide 
Range on Protein: 75-627
Range on HMM: 1-554/554
Sequence Identity: 45% (254 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNEKWLSFIKEMKEKYP-DCTEFNENEQYCVKLLDNFVHFGVHG
|....||||||||||||..|...|..||.||.||...|.|.||||..||...||...|..|..|.||..|.|. ||.||..|....|.|||.|.|.|..|
YHVIRKLGWGHFSTVWLCWDMQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKRDCKEFDPNRCHVVQLLDHFKHRGPNG

KHYCSTFEIMGPNLLDLIQHFDDYKKNMKYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQLNEDYYHQFIEQVKKLDKKPMSMYYLKKQQQKQS
.|||..||..|.|||..|.|..  ...|....|.|||||.||||.|||..||.||||.|||||.|..|.||............|..|.|.. ...|....
NHYCMVFEVLGHNLLKWIKHYN--YQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPENVLLCVNQDYIKRMAAEWTEWQKMGMQMPSSSMVQTAPQ

KQTAKKDKKKEKKKKKKQEAAAAAAAVTQATNQTQDQNSTNNTTTVSEQTIIETSTNENKELNNQKQEEIVKNLQENKETTNNGKNDEKKQENAIDLKEN
.||.....|..|.||||...........|..||.|.|......... |....|...||... |||.||....|.||.||.||..|...||.|...|.||.
HQTQCQQQKMSKNKKKKMKKKQKQQQEQQEKNQQQKQQMEDDQNDN-EDNNQEDNDNEQDNKNNQNQENNMENEQEEKENTNKQKKNQKKKEQHKDKKEQ

QDQNVQKNNND-------NAQEKVETNSTNKQEDSQEKLKQNKEDTKSKNKEDDEKKEKENDSDYSDCESDSDRDEVSEEELYTLKWKNKIPIALDKSLK
..|||||.|||       ..|...||||.|.||..|||..|....||..||. |..||....|..|.|||......   .......|||.....||...|
ECQNVQKQNNDPNFESQNDSQMEQETNSCNNQEHKQEKTMQCQDSTKQQNKQ-DQQKEGQKQSEESECESEDMQEQ---AGKFLVWWKNPRNADLDHKIK

IKIVDFGNACWINKKFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELITNDYLFKPKKRDDTTKNDEHLALFQESLGKFNKQFALSGTKSREFFN
|||.|.|||||....||..||||.||.||.|.|..|....|..|.|||..||.|.||||.|....|....|.|.|...|..||....|||||..||||||
IKIADLGNACWVHHHFTEDIQTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYLFEPHSGEDYSRDDDHIAHIIELCGKIPWHFALSGKYSREFFN

KSGQLIRIKEIQDYPISRILISEYDWDTKEALDIEDFLLPMLHYNPSKRIQAREALQHPWL
|.|.|..|......|....||..|.|...|| ..||||.|||||||.||..|.|.||||||
KKGELRHIPKLKPWPLMNVLIEKYEWSHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL
Kinase 13234.AA CMGC 75-627 14 6.3e-97 319.05 In-house 1-513 (513) Show / Hide 
Range on Protein: 75-627
Range on HMM: 1-513/513
Sequence Identity: 14% (109 aa)

YTIVQKLGWGHFSTVWLAYDKETDSN--------------VALKIQKSKKSYQEAAV-------------DELQLLGDLRKNEKNEKWLSFIKEMKEKYP
|.|..|.|.|....|. ..||.|. .              ||.|. |... |.| |              .|...|  |.||... .|         . .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NW---------QRR

DCTEFNENEQYCVKLLDNFVHFGVHGK-------------HYCSTFEIMGPNLLDLIQHFDDY------------------------KKNMKYWLVRQIA
| ...|... ..|||.| |.| . .|.             | .  || |. .|...|..  ..                        .|..   ..| ..
D-DPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YM

RQCLIGLV--YLHDVCG-MIHTDLKPENVMLQLNEDYYHQFIEQVKKLDKKPMSMYYLKKQQQKQSKQTAKKDKKKEKKKKKKQEAAAAAAAVTQATNQT
.| | ||   |.|  .|  ||.||||||...  | ...... . . |      |    .                                         
YQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRM-M-W-K------S----E-----------------------------------------

QDQNSTNNTTTVSEQTIIETSTNENKELNNQKQEEIVKNLQENKETTNNGKNDEKKQENAIDLKENQDQNVQKNNNDNAQEKVETNSTNKQEDSQEKLKQ
                                                                                                    
----------------------------------------------------------------------------------------------------

NKEDTKSKNKEDDEKKEKENDSDYSDCESDSDRDEVSEEELYTLKWKNKIPIALDKSLKIKIVDFGNACWINKK------------------------FT
                                             | |.     .|. ..|| |||.|.|...                         .|
-------------------------------------------D-W-NPC----QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYT

NNIQTREYRAPETILGID----------YQQNTDVFSFACMIYELITN--------DYLFKPKKRD-----DTTKNDEHLALFQESLGKFNKQFALSGT-
....|| ||||| .||            | .  |. |..|...|..|.        ..||...  .     . ... ..|..  . ||... ... .|. 
HYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKR

------KSREFFNKSGQLIRIK------------EIQD-----------YPISR--ILISEYDWDTK--------------------------------E
      ...|..|... . ..|            .. .           .|  .   . . . |. .                                .
HFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCC

ALDIEDFLLPMLHYNPSKRIQAREALQHPWL
  .  |.|  ||.|.|.||| | .|||||..
DPQAIDLLKKMLQYDPDKRITAEQALQHPYF
Kinase 13234.AA CLK 75-550 17 8.7e-37 107.3 In-house 1-267 (350) Show / Hide 
Range on Protein: 75-550
Range on HMM: 1-267/350
Sequence Identity: 17% (85 aa)

YTIVQKLGWGHFSTVWLAYDKET-DSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNEKWLSFIKEMKEK-YPDCTEFNENEQYCVKLLDNFVH-FGV
|.|| .|| | |..|    | .  .. ||||| .. . | |||  |..                 .|  .||  |...   .    |.|..| | . .| 
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEIN---------------QIMKKINEKHDPNNKYWEH----CWKMNDWFDYGHG-

HGKHYCSTFEIMGPNLLDLIQHFDDYKKNM----------KYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQLN---EDYYHQFIEQVKKLDKK
   | |  ||..| .. |..      |.|           .   .|..|.| .  .  |||. . .||||||||  .       . .    . .||..  
---HICIVFELYGLSIYDFM------KSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDM-KLTHTDLKPENICFVDSRFTHFDCTFKYNHKKKIN--

PMSMYYLKKQQQKQSKQTAKKDKKKEKKKKKKQEAAAAAAAVTQATNQTQDQNSTNNTTTVSEQTIIETSTNENKELNNQKQEEIVKNLQENKETTNNGK
                                                                                                    
----------------------------------------------------------------------------------------------------

NDEKKQENAIDLKENQDQNVQKNNNDNAQEKVETNSTNKQEDSQEKLKQNKEDTKSKNKEDDEKKEKENDSDYSDCESDSDRDEVSEEELYTLKWKNKIP
                                                                                           . . ... .
-------------------------------------------------------------------------------------------KKSNNCVCH

IALDKSLKIKIVDFGNAC---WINKKFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELITNDYLFKPKKRDDTTKNDEHLALFQESLG-KF
.   |.. |...|||.|      . . .  ..|| ||||| |||  . |  || |..| ..|| | . ||      .|  | ||||. .. .|  .
YWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLF------QTHDNREHLAMMERIMGMPI
Kinase 13234.AA S_TKc 75-627 12 2.7e-31 111.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 75-627
Range on HMM: 1-231/231
Sequence Identity: 12% (70 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNEKWLSFIKEMKEKYPDCTEFNENEQYCVKLLDNFVHFGVHGK
|.|..|.| | |..|.....|.|.  ||.|| |                               .. ..|   .. .   .  . |||.| |..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------EHIRREI--QILKK--HHPNIVKLYDVFQD-----D

HYCSTFEIMGP---NLLDLIQHFDDYKKN--MKYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQLNEDYYHQFIEQVK--------KLDKKPMS
|..  .| ..    .|.|.|..    ...  .    .| ...| . .| |.|.  | || ||||||..|            ..|        .|      
HLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE----------HIKICDFGLARQL------

MYYLKKQQQKQSKQTAKKDKKKEKKKKKKQEAAAAAAAVTQATNQTQDQNSTNNTTTVSEQTIIETSTNENKELNNQKQEEIVKNLQENKETTNNGKNDE
                                                                                                    
----------------------------------------------------------------------------------------------------

KKQENAIDLKENQDQNVQKNNNDNAQEKVETNSTNKQEDSQEKLKQNKEDTKSKNKEDDEKKEKENDSDYSDCESDSDRDEVSEEELYTLKWKNKIPIAL
                                                                                                    
----------------------------------------------------------------------------------------------------

DKSLKIKIVDFGNACWINKKFTNNIQTREYRAPETILGIDYQQ-NTDVFSFACMIYELITNDYLFKPKKRDDTTKNDEHLALFQESLGKFNKQFALSGTK
                     |  . |..|.||| .    |     |. |. |..||...   .|            .. ..|.  .             
---------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----------QMQMMFKKIG-------------

SREFFNKSGQLIRIKEIQDYPISRILISEYDWDTKEALDIEDFLLPMLHYNPSKRIQAREALQ-------HPWL
                                      .  ||.  .|...|.||. | ||||       |||.
------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 13234.AA DYRK 467-627 26 9.6e-27 95.17 In-house 146-320 (320) Show / Hide 
Range on Protein: 467-627
Range on HMM: 146-320/320
Sequence Identity: 26% (49 aa)

IKIVDFGNACWINKKFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELITNDYLFKPKKRDDTTKNDEHLALFQESLGKFNKQFALSG--TKSREF
||..||| .| ......  || | ||||| |||. |    |. |. | ..|| |   ||          . . ||...| ||...| .  .|  .. ..|
IKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLF------PGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKF

FNK--------SGQLIRIKEIQDY---PISRILISEYDWDTK--------EALDIEDFLLPMLHYNPSKRIQAREALQHPWL
|..        . . ..|.. ...    .... ....  ...        . ..  ||.. .| ..|.||| . .||||||.
FDCFMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQCDDHQFKDFIKKCLQWDPHKRITPSQALQHPWF
Kinase 13234.AA Pkinase 461-627 22 1.4e-21 77.43 Pfam 141-293 (293) Show / Hide 
Range on Protein: 461-627
Range on HMM: 141-293/293
Sequence Identity: 22% (39 aa)

LDKSLKI----KIVDFGNAC---WINKKFTNNIQTREYRAPETIL-GIDYQQNTDVFSFACMIYELITNDYLFKPKKRDDTTKNDEHLALFQESLGKFNK
.|.   |    || ||| |.   . |. .|    |..|.||| |. | .| .  |..|. |..||...   .|. .  .. . .|.   ...   ...  
IDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHF

QFALSGTKSREFFNKSGQLIRIKEIQDYPISRILISEYDWDTKEALDIEDFLLPMLHYNPSKRIQAREALQHPWL
..  . ..|..|  .  .                . .    ..   .  ||.  .|...|.||. |...|||||.
DWPWWCSISYFF-FRH-W-H--------------F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 13234.AA Ciliate-E2 467-627 15 1.7e-21 70.51 In-house 195-365 (365) Show / Hide 
Range on Protein: 467-627
Range on HMM: 195-365/365
Sequence Identity: 15% (34 aa)

IKIVDFGNA------------CWINKKFTNNIQ-----------------------TREYRAPETILGID---------YQQNTDVFSFACMIYELITND
|||.|||..            . ..|....  .                       | .| ||| . | .         |    |..|. ...||.... 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

YLFKPKKRDDTTKNDEHLALFQESLGKFNKQFALSGTKSREFFNKSGQLIRIKEIQDYPISRI-------LISEYDWDTK--EALDIE--DFLLP----M
. |                                              ..... ... ..         .| . .|  |  . .. |  |..      |
PPF----------------------------------------------QQQIKQCKIDFPCPEWQKDTQCI-QCKW--KSWKKWSQECKDLIKKFGKRM

LHYNPSKRIQ-AREALQHPWL
| ..|.|||. . ..|.|||.
LQKDPEKRITGWEQILNHPWF
Kinase 13234.AA WEE 186-521 12 2.2e-18 58.37 In-house 91-232 (297) Show / Hide 
Range on Protein: 186-521
Range on HMM: 91-232/297
Sequence Identity: 12% (43 aa)

N--LLDLIQHFDDYKKNMKYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQLNEDYYHQFIEQVKKLDKKPMSMYYLKKQQQKQSKQTAKKDKKK
.  |...||.   ... . .|...|| .. . || ..|. |||.| |.||||...  ...  .| . .                                
SNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFI-SKKMNCNQIVNN--------------------------------

EKKKKKKQEAAAAAAAVTQATNQTQDQNSTNNTTTVSEQTIIETSTNENKELNNQKQEEIVKNLQENKETTNNGKNDEKKQENAIDLKENQDQNVQKNNN
                                                                                                    
----------------------------------------------------------------------------------------------------

DNAQEKVETNSTNKQEDSQEKLKQNKEDTKSKNKEDDEKKEKENDSDYSDCESDSDRDEVSEEELYTLKWKNKIPIALDKSLKIKIVDFGNACWINKKFT
                                        ...|. |                                   ..|| ||| .  .|.  .
----------------------------------------DQQNNNDW----------------------------W-FN-MMCKIGDFGHVTDMNSNNN

NNIQT----REYRAPETILG-IDYQQN--TDVFSFACMIYELITN
|  |.    ..| |||.. |  .|  .   |.||....|||| .|
NPHQEQEGDSRYMAPEILQGYYHYTHLYKADIFSLGITIYELACN
Kinase 13234.AA DyrkP 466-526 40 9.2e-15 44.38 In-house 146-206 (323) Show / Hide 
Range on Protein: 466-526
Range on HMM: 146-206/323
Sequence Identity: 40% (25 aa)

KIKIVDFGNACWINKKFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELITNDYLFK
..||.||| .|.|       .| | ||||| |.|  |    |..|  |.. || |   ||.
QVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVLFQ
Kinase 13234.AA DYRK1 466-525 41 3.5e-13 42.16 In-house 144-203 (321) Show / Hide 
Range on Protein: 466-525
Range on HMM: 144-203/321
Sequence Identity: 41% (25 aa)

KIKIVDFGNACWINKKFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELITNDYLF
.|||.||| .|  ...  . || | ||.|| .|||.|.   |..|  |.. |. | . ||
AIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLF
Kinase 13234.AA DYRK2 467-520 45 3.5e-13 38.87 In-house 143-197 (318) Show / Hide 
Range on Protein: 467-520
Range on HMM: 143-197/318
Sequence Identity: 45% (25 aa)

IKIVDFGNACWINK-KFTNNIQTREYRAPETILGIDYQQNTDVFSFACMIYELIT
||..|||  |  .  ..   ||.| ||||| |||. |   .|  || | . || |
IKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYT
Kinase 13234.AA DYRK 75-134 30 3.1e-12 42.3 In-house 1-60 (320) Show / Hide 
Range on Protein: 75-134
Range on HMM: 1-60/320
Sequence Identity: 30% (18 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNEK
|.|.. .| | |. |  ..|. |.  ||.|| ...|...  | .|...|  |... ...|
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDK
Kinase 13234.AA HIPK 466-519 43 1.5e-11 32.11 In-house 143-197 (329) Show / Hide 
Range on Protein: 466-519
Range on HMM: 143-197/329
Sequence Identity: 43% (24 aa)

KIKIVDFGNACWINKKFTNN-IQTREYRAPETILGIDYQQNTDVFSFACMIYELI
..|..||| |  . |  .|  .| | ||||| |||. . .| |..|  | | ||.
RVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELF
Kinase 13234.AA DYRK2 75-133 32 1.1e-09 27.39 In-house 1-59 (318) Show / Hide 
Range on Protein: 75-133
Range on HMM: 1-59/318
Sequence Identity: 32% (19 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNE
|.|.  .| | |  |  .||. |.  ||.|.   || . . |. |.. |  .|.. |..
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDN
Kinase 13234.AA CLK 607-627 61 1.6e-09 23.96 In-house 330-350 (350) Show / Hide 
Range on Protein: 607-627
Range on HMM: 330-350/350
Sequence Identity: 61% (13 aa)

MLHYNPSKRIQAREALQHPWL
|| | ||||| ...|||||. 
MLEYDPSKRITCKDALQHPFF
Kinase 13234.AA DYRK 153-239 35 1.7e-09 31.93 In-house 57-138 (320) Show / Hide 
Range on Protein: 153-239
Range on HMM: 57-138/320
Sequence Identity: 35% (32 aa)

NENEQYCVKLLDNFVHFGVHGKHYCSTFEIMGPNLLDLI--QHFDDYKKNMKYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQ
.... .||...| |    .| .| | .|| .  || ...   ||. .   .   |||..|.| | .|..||     || ||||||.||.
PDDKYHCVHMYDYF----YHRNHLCIVFELLSMNLYEFLKNNHFQGF---FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLK
Kinase 13234.AA DYRK1 75-135 37 2.9e-09 28.16 In-house 1-61 (321) Show / Hide 
Range on Protein: 75-135
Range on HMM: 1-61/321
Sequence Identity: 37% (23 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNEKW
| |   .| | |  |  |||...   ||.|| | ||.. . |  |..||  . |..|..|.
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKY
Kinase 13234.AA DYRK2 602-627 38 1.4e-08 23.72 In-house 293-318 (318) Show / Hide 
Range on Protein: 602-627
Range on HMM: 293-318/318
Sequence Identity: 38% (10 aa)

DFLLPMLHYNPSKRIQAREALQHPWL
||..  ..  ||.|. ...||.|||.
DFIKRCFEWDPSERMTPSQALKHPWI
Kinase 13234.AA DYRK2 159-238 39 1.9e-08 23.26 In-house 63-135 (318) Show / Hide 
Range on Protein: 159-238
Range on HMM: 63-135/318
Sequence Identity: 39% (33 aa)

CVKLLDNFVHFGVHGKHYCSTFEIMGPNLLDLIQHFDDYKKNMK----YWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVML
||..|| ...|    .| | ||| .. || ..|      ||| .      |||  |.. | .|. ||     || ||||||..|
CVHMLD-YFYF---RNHHCITFELLSMNLYEYI------KKNHFQGFSLQLVRRFAHSILQCLRFLH-KNNIIHCDLKPENILL
Kinase 13234.AA Pkinase 180-238 30 5.1e-08 29.45 Pfam 79-141 (293) Show / Hide 
Range on Protein: 180-238
Range on HMM: 79-141/293
Sequence Identity: 30% (20 aa)

FEIMGP-----NLLDLIQHFDDYKKNM--KYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVML
.| ..       | |.|.   ......   .| .. ...| | || |.|. .| || ||||||...
MEYCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILI
Kinase 13234.AA Ciliate-E2 75-113 28 3.1e-07 20.88 In-house 1-37 (365) Show / Hide 
Range on Protein: 75-113
Range on HMM: 1-37/365
Sequence Identity: 28% (11 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQ
| ...|.| | |..|... ..... ..|.||.. .|. |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-Q
Kinase 13234.AA HIPK 172-238 38 6e-07 17.39 In-house 71-134 (329) Show / Hide 
Range on Protein: 172-238
Range on HMM: 71-134/329
Sequence Identity: 38% (26 aa)

HGKHYCSTFEIMGPNLLDLIQHFDDYKKNMKYWLVRQIARQCLIGLVYLHDVCGMIHTDLKPENVML
| .| |  ||..  || |           .|.  .| |  | |  |. | .  |.|| ||||||.||
HKNHTCLVFEMLEQNLYDFQKQNKFMPLPLKH--IRPILQQVLTALMKLKEL-GLIHADLKPENIML
Kinase 13234.AA DYRK1 601-627 40 3e-06 17.68 In-house 295-321 (321) Show / Hide 
Range on Protein: 601-627
Range on HMM: 295-321/321
Sequence Identity: 40% (11 aa)

EDFLLPMLHYNPSKRIQAREALQHPWL
.| .. ||.|.| .||.  .||||...
KDLIKRMLQYDPKQRITPYYALQHSFF
Kinase 13234.AA HIPK 75-133 28 5e-06 14.33 In-house 1-59 (329) Show / Hide 
Range on Protein: 75-133
Range on HMM: 1-59/329
Sequence Identity: 28% (17 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLLGDLRKNEKNE
| ..  || | |  |  .  . |.  ||.|| |   .|      |...|  |.. . .|
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE
Kinase 13234.AA Pkinase 75-105 41 6e-06 22.19 Pfam 1-31 (293) Show / Hide 
Range on Protein: 75-105
Range on HMM: 1-31/293
Sequence Identity: 41% (13 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKI
|.|..|.| | |..|.....| |   ||.||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI
Kinase 13234.AA DyrkP 602-627 46 8e-06 14.47 In-house 298-323 (323) Show / Hide 
Range on Protein: 602-627
Range on HMM: 298-323/323
Sequence Identity: 46% (12 aa)

DFLLPMLHYNPSKRIQAREALQHPWL
||   .|     .|  |.|||||||.
DFVRQCLQIDFTRRPTAKEALQHPWF
Kinase 13234.AA DYRK1 168-238 33 1.7e-05 14.74 In-house 69-137 (321) Show / Hide 
Range on Protein: 168-238
Range on HMM: 69-137/321
Sequence Identity: 33% (24 aa)

HFGVHGKHYCSTFEIMGPNLLDLIQHFDDYKKNMKYWLVRQIARQCLIGLVYLHDV-CGMIHTDLKPENVML
|| ..  | |  ||..  || ||..  .   . .   |.|..|.| .  |...      .|| ||||||..|
HF-MFRNHLCLVFELLSYNLYDLLRNTH--FRGVSLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILL
Kinase 13234.AA DyrkP 206-239 44 3.5e-05 12.27 In-house 108-140 (323) Show / Hide 
Range on Protein: 206-239
Range on HMM: 108-140/323
Sequence Identity: 44% (15 aa)

VRQIARQCLIGLVYLHDVCGMIHTDLKPENVMLQ
. .|  | ||.| |.| .  .|| ||||||....
LQKITQQILIALDYIHSLR-LIHCDLKPENILMK
Kinase 13234.AA DyrkP 75-123 34 9.6e-05 10.8 In-house 1-49 (323) Show / Hide 
Range on Protein: 75-123
Range on HMM: 1-49/323
Sequence Identity: 34% (17 aa)

YTIVQKLGWGHFSTVWLAYDKETDSNVALKIQKSKKSYQEAAVDELQLL
| |.  ||   ||      || |.  . .||    | | . ..||..||
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLL
Kinase 13234.AA Ciliate-E2 209-238 36 0.004391 6.41 In-house 165-194 (365) Show / Hide 
Range on Protein: 209-238
Range on HMM: 165-194/365
Sequence Identity: 36% (11 aa)

IARQCLIGLVYLHDVCGMIHTDLKPENVML
.... . .| |||     || |.||||...
YIACIILALEYLHSKNNIIHRDIKPENILF
Kinase 13234.AA WEE 75-89 46 0.005107 6.05 In-house 1-15 (297) Show / Hide 
Range on Protein: 75-89
Range on HMM: 1-15/297
Sequence Identity: 46% (7 aa)

YTIVQKLGWGHFSTV
...|||.| | |..|
FQEVQKIGEGSFGEV
Kinase 13234.AA HIPK 607-627 42 0.00668 4.42 In-house 309-329 (329) Show / Hide 
Range on Protein: 607-627
Range on HMM: 309-329/329
Sequence Identity: 42% (9 aa)

MLHYNPSKRIQAREALQHPWL
|.  .. |||   |||.||. 
MCTWDAHKRITPCEALNHPFV
Kinase 13234.AA WEE 607-627 42 0.011425 4.86 In-house 277-297 (297) Show / Hide 
Range on Protein: 607-627
Range on HMM: 277-297/297
Sequence Identity: 42% (9 aa)

MLHYNPSKRIQAREALQHPWL
|.| .|..|. ... |||| |
MMHPDPEQRPTCQQLLQHPVL