Gene 7690 (Tetrahymena)

7690

Species: Tetrahymena
Alias: 725, PreTt07690, 7690, TTHERM_01347900, 339.m00009
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: RCK

Sequence

Name Sequence Type Origin Length Description Download
7690.AA Protein None 407 None Fasta, JSON
7690.kin_dom Protein Kinase Domain None 281 None Fasta, JSON
7690.NA RNA None 1224 None Fasta, JSON

Protein domain

Protein domains of 7690.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7690.AA RCK 4-284 60 2.8e-223 715.75 In-house 1-298 (298) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-298/298
Sequence Identity: 60% (180 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKFH-HPNIVNLYEIIKHNN--ELFFVFEYMDQNVYQMTKD---REKP
|.| ..|||||.|.||||.....|..||||||| .|...|||...|.||.||.|.. ||||..|.|.|..|.  .|.|||||||.|.|||.||   |.|.
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKY

FTENQ--IRNIIYQTLQGLAYIHRHGYFHRDLKPENLLES----------NNTIKIADFGLAREIRSKPPFTDYVSTRWYRAPEVILRANNYNSPIDIFA
..|||  |.||.||.|||||..|.||.|||||||||.. .          ...||||||||.||||||||.|||||||||||||..||...||||.||.|
LPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWA

IGCIMAELYKLWPLFPGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQKMLRYSPQKRISAYAALQHPFF
.||||.||| |.|||||..|.||| .||||||||.|..||.||||||....||||.|..||..||||.|...|.|..|||.. |||||.|..|||||.|
VGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 7690.AA MAK 4-284 46 4.3e-165 529.88 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-352/352
Sequence Identity: 46% (165 aa)

YKIGATLGDGTFGVVMKAVD------------------------------ETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKFH-HPNIVNLYEIIK-
| .   |||||.| ||.| .                                .| .||||.|| ||   ||| ..| |. || |   ||||| | |.|  
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMK-KKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRD

-HNNELFFVFEYMDQNVYQMTKDREK-PFTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESN------------------NTIKIADFGLAREIR
  |..|.|||||| .| ||| |||..  | |  ||||.|| |||||..|.||.||||.||||.. .                     |||||||||||||
SENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIR

SKPPFTDYVSTRWYRAPEVILRANNYNSPIDIFAIGCIMAELYKLWPLFPGQNELDQILQICKVMGTPSKEE----------------WPEGYKLASGVG
||||.|||||||||||||| ||  .|.||||. |.|||||||| . ||||| .| |||  ||.|.||| |..                ||.||.||.  .
SKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMN

YNFPQYKP---QPLQELIPNASP-EAIDLLQKMLRYSPQKRISAYAALQHPFF
. |||  |    ||..||||.|. .||.|...||.. |.||  |  ....|.|
FRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase 7690.AA CMGC 4-284 26 5e-139 459.97 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-513/513
Sequence Identity: 26% (139 aa)

YKIGATLGDGTFGVVMKAVD--------------ETNGQVVAIKKMKSKKCPKWEEI----------IKLPEITSLMKF-----------------HHPN
|.|   .| ||.||| |..|                ....|||||.|...  ....           . | ||  |...                 ||.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVNLYEIIKHNN-----------------ELFFVFEYMDQNVYQMTKD--------REKPFTENQ------------IRNII------YQTLQGLA--YI
||.||.|..|.|                 .|..||||||.. ||. |.        | .|..| .            |....      || |.||.  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HRHG--YFHRDLKPENLLESNNT---------------------IKIADFGLAR--EIRSKP--------------------PFTDYVSTRWYRAPEVIL
|.|.   .||||||||.| ..|.                     .||.||||||  ...|..                    |.|.||.||||||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

RA---------NNYNSPIDIFAIGCIMAELYK--------LWPLFPGQNE-----------LDQILQICKVMGTPS---------------KEEWPE---
..         ..|..|||. ..|||.||.|         ..|||||..|           .||. .|.||.|||.               .||||.   
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

----------------------GYKLASGVGYNFPQYKPQPLQELIPN-----------------------------------ASPEAIDLLQKMLRYSP
                      .....   . .||...|.|...|.|.                                   ..|.|||||.|||.| |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

QKRISAYAALQHPFF
.|||.|  |||||.|
DKRITAEQALQHPYF
Kinase 7690.AA CDK7 4-284 37 6.6e-105 280.33 In-house 1-288 (288) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-288/288
Sequence Identity: 37% (108 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMK----SKKCPKWEEIIKLPEITSLMKFHHPNIVNLYEIIKHNNELFFVFEYMDQNVYQMTKDREKPFT
|.. . .| |.|..| || |   ||.||||| |            .   . ||  |   .|.|...|  |. |   .  ||..||       || .  .|
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

ENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESNN-TIKIADFGLAREIRS-KPPFTDYVSTRWYRAPEVILRANNYNSPIDIFAIGCIMAELYKLW
   | ..  .||||| | ||.   |||||| ||| . |  .||||||||| . |    .|  | ||||||||    |  | . .|. ..|||.|||    
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFPGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGY-NFPQYKPQPLQELIPNASPEAIDLLQKMLRYSPQKRISAYAALQHPFF
| .||....||.  |.. .|||. ||||.  .... .   .|| |   ||...   || ...||...|.   |.||...  .|..|.|
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 7690.AA CDK 4-284 35 2.4e-104 334.75 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-284/284
Sequence Identity: 35% (114 aa)

YKIGATLGDGTFGVVMKAVDETNG-----QVVAIKKMKSKK--CPKWEEIIK---LPEITSLMKFHHPNIVNLYEIIKHN-----------NELFFVFEY
|.. . .| ||.||| || |  .|     |.||.|| .  .    . .| .    . ||. |..  |||||.|.... ..           | |..||||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MDQNVYQMTKDREKPFTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESNNT------IKIADFGLAREIRS-------KPPFTDYVSTRWYRAPE
||.  ..  .          |.....| |.||.|.|...  |||||| |.| .||       .|||||||||.  .         ..|  | |.||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

VILRANNYN--SPIDIFAIGCIMAELYK---LWPLFPGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQKM
. | . .|.   |||. ..|||.||..      |||||..|.||.  |....|||. . ||.  ||                            |||.||
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNKM

LRYSPQKRISAYAALQHPFF
| | |.||||| .|||||.|
LCYDPKKRISAEQALQHPYF
Kinase 7690.AA S_TKc 4-284 31 8.6e-99 335.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-231/231
Sequence Identity: 31% (95 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKFHHPNIVNLYEIIKHNNELFFVFEYMDQ---NVYQMTKDREKP---
|.|. ..| |.||.|.|...   |..||||..|         .  . ||  |.| ||||||.||... . ..|..|.||.|.   ..... |.| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESNNTIKIADFGLAREIRSKPPFTDYVSTRWYRAPEVILRANNYNS-PIDIFAIGCIMAELY
  |.| ..| ..||....|.|.|.||  ||||||||.| .. .|||.||||||..      | .. |.||.||||.     |.  ..|. ..|||..|..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

KLWPLFPGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQKMLRYSPQKRISAYAALQ-------HPFF
   |.||   ..........                                       ||||.|...|.|.. |.||..|  |||       ||.|
CGYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 7690.AA CDC2 4-284 38 1.4e-98 303.62 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-301/301
Sequence Identity: 38% (120 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEII------KLPEITSLMKFH-HPNIVNLYEIIKHNNELFFVFEYMDQNVYQMTK---D
|.    .| ||.||| |. |   .|.||.|| . .     |. .       . ||  | .   ||||| | ..|.  | |. ||||.|..  . ..    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQ----EDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIP

REKPFTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESNN-TIKIADFGLAREIRS-KPPFT--DYVSTRWYRAPEVILRANNYNSPIDIFAIGCI
 .|..... .....|| |||... |... .|||||| |.| ... .|||||||||| .   . . |    | |.||||||. |..  |. |.|. .||||
KNKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCI

MAEL---YKLWPLFPGQNELDQILQICKVMGTPSKEEWPEGYKLA--SGVGYNFPQYKPQPLQELIPN---------ASPEAIDLLQKMLRYSPQKRISA
.||.       |||.|. | ||. .| ...|||. ..||. ..|         ||..||| |....||         . ||.||||..||.| |||||||
FAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT---FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISA

YAALQHPFF
 .|||||.|
KEALQHPYF
Kinase 7690.AA Pkinase 4-284 32 1.2e-93 322.26 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-293/293
Sequence Identity: 32% (99 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLP--EITSLMKFHHPNIVNLYEIIKHNNELFFVFEYMDQNVYQMTKDR-------
|.|| ..| |.||.| |...  .|..||.|..| ..  .|......   ||  . ...||||| ||..   .... .|.||..  .|             
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

EKPF--TENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLES-NNTI----KIADFGLARE--IRSKPPFTDYVSTRWYRAPEVILRANNYNSPIDIFA
...|  .|.......||.|.||.|.|..|  ||||||||.| . |..|    ||.|||||.   . ... .|... |.||.|||||. .. | ...|...
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGCIMAELYKLWPLFPGQ----NELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQKMLRYSPQKRISAYAALQH
.|||..|..   |.|||.    | .||.  ||..||.| ...||. .        .. . . . .... .|.|.|..|.. ..|.. |.||..|  .|||
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PFF
|.|
PWF
Kinase 7690.AA MOK 4-284 38 8.1e-89 278.45 In-house 1-283 (283) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-283/283
Sequence Identity: 38% (108 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKFH-HPNIVNLYEII--KHNNELFFVFEYMDQNVYQMTKDREKPFTE
||    .|.|||  |||     .|.  | |.|| ..    |.. .| ||  . .   ||||..| |..  .   .|  . | || |.| . . |  .  .
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMK-QHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQ

NQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLLESNNTIKIADFGLAREIRSKPPFTDYVSTRWYRAPEVILRANNYNSPIDIFAIGCIMAELYKLWPLF
..|.. .|| .. |  .|| | |||| ||||.|  .  .|.||||  | . || |.|.|.||||||||| .|    |   .|....||.  |.  | |||
KKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLF

PGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQKMLRYSPQKRISAYAALQHPFF
|| ||.||| .|  ||||| ..      . . .. |.||  |   .. |.||... ......||  | |  ||.|  ..|||.|
PGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase 7690.AA CDKL 4-284 37 2.2e-83 283.32 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-286/286
Sequence Identity: 37% (108 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKFHHPNIVNLYEIIKHNNELFFVFEYMDQNVYQMTKDREKPFTENQI
| . . .| |  |||||  .  .||.||||| |  .  . .  | . ||  |  ..|.||||| |. . ...|. ||||.| .|    . . .   |...
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

RNIIYQTLQGLAYIHRHGYFHRDLKPENLLES--NNTIKIADFGLAREIRSKPP--FTDYVSTRWYRAPEVILRANNYNSPIDIFAIGCIMAELYKLWPL
|....|.|..... | |   ||| ||||.| .  | ..|. |||.|| . .||    |||| ||||||||  .    | .|.|| ||||.|||.    ||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPL

FPGQNELDQILQICKVMGTPSKEEWPEGYKLASGVGYNFPQ-YKPQPLQELIPNAS-PEAIDLLQKMLRYSPQKRISAYAALQHPFF
.|||...||   | |..|.   .     .|    .|  ||.  ...|| .  ||.| ..|.|...|.|  .| .|...  ...||.|
WPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 7690.AA MAPK 58-284 37 2.5e-82 279.85 In-house 61-328 (328) Show / Hide 
Range on Protein: 58-284
Range on HMM: 61-328/328
Sequence Identity: 37% (100 aa)

F-HHPNIVNLYEIIKHN-----------NELFFVFEYMDQNVYQMTKDREKPFTENQIRNIIYQTLQG--LAYIHRHGYFHRDLKPENLL-ESNNTIKIA
| ||.||..|..|..             |.. .|.|.|. . .|  | .  | ..  |. ..|| | |  | |||  .  ||||||.|.|  .| . ||.
FHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKIC

DFGLAREIRSK-------PPF--------TDYVSTRWYRAPEVILR--ANNYNSPIDIFAIGCIMAELYK-LWPLFPGQNELDQILQICKVMGTPSKEEW
|||||| | ..       . .        |.||.||||||||..|   ...|.  .|. ..|||.||...   |||||.. .||. .| .|.||||.| .
DFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFI

-PEG-YKLASGVGYNF---PQYKPQPLQELIPN----ASPEAIDLLQKMLRYSPQKRISAYAALQHPFF
   . .. |  .  ..   |.|...|.....||    |.|.|||||.|||  .|.|||..  |||||.|
QCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 7690.AA ERK 58-284 38 3.7e-72 246.02 In-house 60-307 (307) Show / Hide 
Range on Protein: 58-284
Range on HMM: 60-307/307
Sequence Identity: 38% (96 aa)

FH-HPNIVNLYEIIKHN-----NELFFVFEYMDQNVYQMTKDREKPFTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPENLL-ESNNTIKIADFGLAR--
|. |.||..|. |.. |     |.. .|.|.|.    |  . .  . ..  . . .||.| || |||  . .|||||| |.|  || . ||.||||||  
FKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIINSQQ-ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCF

--EIRS-----KPPFTDYVSTRWYRAPEVILRANNYNSPIDIFAIGCIMAELYKLWPLFPGQNELDQILQICKVMGTP-SKEEWPEG-YKLASGVGYNFP
  .. .     .. .|.||.||||||||..| ...|....|| ..|||.||...  ||||| . ..|| .| ...||| |.|.  .  .. |     |.|
DASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMDIWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLP

Q--YKPQPLQELIPNAS--PEAIDLLQKMLRYSPQKRISAYAALQHPFF
   ..|.|.....|||.  |.|||||.|||   |.|||..  .|.||.|
NPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVEECLEHPYF
Kinase 7690.AA Pkinase_Tyr 4-127 25 5.9e-15 51.27 Pfam 1-137 (270) Show / Hide 
Range on Protein: 4-127
Range on HMM: 1-137/270
Sequence Identity: 25% (35 aa)

YKIGATLGDGTFGVVMKAVDE----TNGQVVAIKKMKSKKCPK---WEEIIKLPEITSLMKF-HHPNIVNLYEIIK-HNNE--LFFVFEYMDQ-NVYQMT
 ..| .|| | ||.|.|..       ... ||.|..| .  ..   .|. ..  |.  .... ||||||.|| ..  .     .. |.|||   . .   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KDR---EKPFTENQIRNIIYQTLQGLAYIHRHGYFHRDL
...   ..|.|  .. .. .|  .|..| ..... ||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 7690.AA TyrKc 4-284 20 1.6e-14 12.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-284
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

YKIGATLGDGTFGVVMKAVDETNGQVVAIKKMKSKKCPKWEEIIKLPEITSLMKF--HHPNIVNLYEIIKHN-------NELFFVFEYMD----QNVYQM
 . | .|| | ||.|.|..     . ||.|..|. .    |....  |.  ..|.  ||||||.|| .. .          |. |.|||.    ..  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR--EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TKDREKPFTENQIRNIIYQTLQGLAYIHRHGYFHRDLKPEN-LLESNNTIKIADFGLAREIRSK-------PPFT------DY--VSTRWYRAPEVILRA
....   ..  .  .. .|  .| .|.|.... ||||   | |. .|.|.||.||||.|.| ..          .          .  ||. |||.| . 
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NY

NNYNSPIDIFAIGCIMAELY----KLWPL----FPGQNELDQILQICKVMGTPSK----EEWPEGYKLASGVGYNFPQYKPQPLQELIPNASPEAIDLLQ
. ...  |... |  | |..    . .|     .    |. . ..  . |  |                                   . ...|  .. .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------FVCCPDEMYQIMK

KMLRYSPQKRISAYAALQHPFF
.  .. | .| .  .   | .|
QCWHEDPEDRPTFSEI--HECF
Kinase 7690.AA MAPK 4-35 39 4.7e-09 27.21 In-house 1-38 (328) Show / Hide 
Range on Protein: 4-35
Range on HMM: 1-38/328
Sequence Identity: 39% (15 aa)

YKIGATLGDGTFGVVMKAVDET------NGQVVAIKKM
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YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI
Kinase 7690.AA ERK 4-34 44 1.9e-08 27.78 In-house 1-36 (307) Show / Hide 
Range on Protein: 4-34
Range on HMM: 1-36/307
Sequence Identity: 44% (16 aa)

YKIGATLGDGTFGVVMKAVDET-----NGQVVAIKK
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YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKK
Kinase 7690.AA Pkinase_Tyr 132-150 63 3.6e-05 18.15 Pfam 143-161 (270) Show / Hide 
Range on Protein: 132-150
Range on HMM: 143-161/270
Sequence Identity: 63% (12 aa)

LLESNNTIKIADFGLAREI
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LVTENNVVKICDFGLARDI