Gene 7876 (Tetrahymena)

7876

Species: Tetrahymena
Alias: 73.m00120, 7876, 326, TTHERM_00557780, PreTt07876, 3735.m00014
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: GSK

Sequence

Name Sequence Type Origin Length Description Download
7876.AA Protein None 391 None Fasta, JSON
7876.kin_dom Protein Kinase Domain None 310 None Fasta, JSON
7876.NA RNA None 1176 None Fasta, JSON

Protein domain

Protein domains of 7876.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7876.AA GSK 34-343 50 4.6e-208 642.34 In-house 1-328 (328) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-328/328
Sequence Identity: 50% (172 aa)

LKIIDVVGNGTFGVVYKKLDDNINFNYLKMKALLNKEQV----VAVKRVFQDKRYK-NREREIIERL---DHQNIIKCKDFFETKGEKKDE--VYLN-LV
.....|.|.|.|||||.  . ....         .....    ||.|.|.|||||| ||| .|...|   ||.||...| ||....|||||  ||.| ||
YEEMKVIGHGSFGVVYQAYMNSPSN---------ETKEIWLGPVAIKKVWQDKRYKCNRELQIMKMLGKLDHPNIVRLKYFFYMHYEKKDENHVYCNCLV

MEFMNFPLSKVIRDKRKANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIP--NEANISYICSRYYRAPEL
||.|.  |..|||...|..|.|.| .|.||.||||..|.||.|..|||||||||||||....   .||||||||||||.|  ||.|||||||||||||||
MEYMPQTLYQVIRHYVKNKQQMPIIHIKLYMYQMFRGLAYLHSHGICHRDIKPQNILVDPDT--GVLKICDFGSAKQLEPNKNEPNISYICSRYYRAPEL

IFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGENSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFP-----QIKSYSWSKVFEK---------------
||....||..||.||.|||.|||..|.|||||..|.|||||||..|||||..|| .||| ..||.||     |||...|.|...|               
IFGCTNYTCQIDVWSCGCVMAEMLKGQPLFPGDSSVDQLVEIIKMLGTPTKEQIQSMNPSYPEFKFPYWSFQQIKPHPWQKNDTKYEYQTYYHKKYRTVY

SLQKVSEDEKQKFNQLMDLISRVLVYAPSERPSPLQALAHPFF
 .... .|..    ...||||..|||.|..|.|||.|.|||||
MFKWCHTDMQ----DWIDLISKCLVYDPKKRLSPLEACAHPFF
Kinase 7876.AA CMGC 34-343 22 1.1e-119 395.2 In-house 1-513 (513) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-513/513
Sequence Identity: 22% (119 aa)

LKIIDVVGNGTFGVVYKKLDDNINFNYL--KMKALLNKEQVVAVKRVFQDKRYKN----------------REREIIERL-----------------DHQ
 .||...| ||.|||||  | . |....  . ... . ...||.|...... |..                || .| ..|                 .| 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQ-AHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHN

NIIKCKDFFETKGEKKDE-----------VYLNLVMEFMNFPLSKVIRDKRK------------------------ANQVMRIEDIRLYAYQMFKALS--
||.|..|.| .|.....|           ..|.||.|.|   | ..|.....                          . . | .|| |.||....|   
NIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLK

YLQSLN--ICHRDIKPQNILVNDKDDD-----------------KRLKICDFGSAKQLIPN----------------------EANISYICSRYYRAPEL
|. | .  |.|||.||.|||.|.. .                   ||||||||.|... |.                      ... .|...|.|||||.
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEI

IFKS---------QHYTNAIDMWSMGCVIAEMVLG--------EPLFPGENS-----------LDQLVEIIRILGTPT---------------RQQILMM
.. .         .||| .||||| ||..|||..|        .|||||...           .||| .|...|||||                ...  |
LLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNM

NPTSQEFR---------------------------FPQIKSYSWSKVFEKSL-----------------QKVSEDEK--------QKFNQLMDLISRVLV
..    .                            ||...  .|...| ..                   |. .. |        .   |. ||... |.
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-KFNHQFKRKCCDPQAIDLLKKMLQ

YAPSERPSPLQALAHPFF
| |..|... |||.||.|
YDPDKRITAEQALQHPYF
Kinase 7876.AA S_TKc 34-343 25 2.8e-84 287.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-231/231
Sequence Identity: 25% (81 aa)

LKIIDVVGNGTFGVVYKKLDDNINFNYLKMKALLNKEQVVAVKRVFQDKRYKNREREIIERLDHQNIIKCKDFFETKGEKKDEVYLNLVMEFMNF---PL
 .|....| |.||.|||  . .               ..||.|..    .   ||..| .. .| ||.|..|.|..        .| .|||...     |
YEILRKIGKGAFGKVYKCRHKK-------------TGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDL

SKVIRDKRK--ANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIPNEANISYICSRYYRAPELIFKSQHYT
 ..|.....   ....   ..| |.||...|| |. |..|.|||.||.|||...     ..||||||.|.||       ... ...|.|||..    .|.
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYG

N-AIDMWSMGCVIAEMVLGEPLFPGENSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQKVSEDEKQKFNQLMDLISRVLVYA
  ..|.|| ||...||. |.|.||      |. ......|                                               .. |.|.. |.. 
KCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------------------------------------------SPEAKDFIRKCLQKD

PSERPSPLQALA-------HPFF
|..||.  .||.       ||.|
PEKRPTA-EALQDEWDIKCHPWF
Kinase 7876.AA Pkinase 34-343 30 4.9e-78 270.36 Pfam 1-293 (293) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-293/293
Sequence Identity: 30% (100 aa)

LKIIDVVGNGTFGVVYKKLDDNINFNYLKMKALLNKEQVVAVKRVFQDKRYKNR--------EREIIERLDHQNIIKCKDFFETKGEKKDEVYLNLVMEF
..|. ..| |.||.|||  . . .              .||||..  ... ..         | .|  ||.| ||....|.||.    ||..|  .|||.
YHIGRKIGSGSFGCVYKCHHKGTGK-------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIY--MVMEY

MNFPLSKVIRDK----RKANQVM--RIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVN-DKDDDKRLKICDFGSAKQ--LIPNEANISYICSRYYR
..  |. |.  .    .... ..    .... |.||....| |. | .|.|||.||.|||.. . . | ..||||||.|||  . .|. . .. ....|.
CEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYM

APELIFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGE----NSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQKVSEDEKQK
|||.| ..|.|. ..||||.||...||..|.|.|||.    | .||.. | ||.|.|.. ..   .. | .| |.. .     . ...   ..||.    
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---F-HWTF-HNWSEE----

FNQLMDLISRVLVYAPSERPSPLQALAHPFF
   . |.|.. | . |..||.. |.| ||.|
---CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 7876.AA CDK 68-343 31 2.6e-63 201.35 In-house 20-284 (284) Show / Hide 
Range on Protein: 68-343
Range on HMM: 20-284/284
Sequence Identity: 31% (100 aa)

NKE-------QVVAVKRVF--------QDKRYKN---REREIIERLDHQNIIKCKDFFETK-----GEKKD-EVYLNLVMEFMNFPLSKVIRDKRKANQV
.|.       |.|| |..          .        ||  .   | |.||.| .| . ||     . |   |  | .|.|.|   |.|...        
DKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNN-KDKHENKLYMVFEYMDHDLKKYMD--------

MRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDK--RLKICDFGSAKQL-I------PNEANISYICSRYYRAPELIFKSQHYT--NAID
     |. | .|. ..|.|. | .| |||.||||||.|..   |  |||| ||| |.   |      || .  . .  . |||||| . |.||.   .||
-----IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPID

MWSMGCVIAEMVL---GEPLFPGENSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQKVSEDEKQKFNQLMDLISRVLVYAPS
||| ||..|||..   ..|||||.. .|||  |.||.|||| ..             | .... .                       ||... |.| |.
MWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDN------------WPGVTKLPDY----------------------DLLNKMLCYDPK

ERPSPLQALAHPFF
 | |  ||| ||.|
KRISAEQALQHPYF
Kinase 7876.AA MAPK 87-343 31 3.5e-58 199.63 In-house 53-328 (328) Show / Hide 
Range on Protein: 87-343
Range on HMM: 53-328/328
Sequence Identity: 31% (92 aa)

REREIIERL-DHQNIIKCKDFFETK-----GEKK--DEVYLNLVMEFMNFPLSKVIRDKRKANQVMRIEDIRLYAYQMFKA--LSYLQSLNICHRDIKPQ
||  .  .. .| |||| .| |  .     ...   ...|  .|||.|   | ..|.  .     .  . |.   ||. ..  | |. | |. |||.|| 
REIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIY--IVMELMETDLHQIIKSQQ----PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPS

NILVNDKDDDKRLKICDFGSAKQLIPNEANI---------------SYICSRYYRAPELIFK--SQHYTNAIDMWSMGCVIAEMVL-GEPLFPGENSLDQ
|||||  .|   ||||||| | .. |..  .                |.  |.|||||...   ..||| |.|||| ||  |||.  . |||||....||
NILVNENCD---LKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQ

LVEIIRILGTPTRQQILMMN-P--TSQEFR----FPQIKSYSWSKVFEKSLQKVSEDEKQKFNQLMDLISRVLVYAPSERPSPLQALAHPFF
.  |. .||||... |  .  .    . ..    .|. . ..|.|.| ...        ..  |  ||... ||  |..| .  .||.||.|
WNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANF-------NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 7876.AA Ciliate-E2 34-343 19 3e-56 191.56 In-house 1-365 (365) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-365/365
Sequence Identity: 19% (85 aa)

LKIIDVVGNGTFGVVYKK--LDDNINFNYLKMKALL---------NKEQVVAVKRV-FQDKRYKNREREII----------------ERLDHQNIIKCKD
 |.| . |.|.||.|||     .. .|.. . .  .         .| . .|.|..  ........|  |.                |.|.| ||||...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

FFETKGEKKDEVYLNLVMEFMNFP-LSKVIRDKRK--------ANQVMRIEDIRLYAYQMFK---------------ALSYLQSLN-ICHRDIKPQNILV
.|..    ||. .. ||||. .   | . |....|        . . . .. |. . .| ..               || || | | |.||||||.|||.
CFQE----KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

NDKDDDKRLKICDFGSAKQLIPNEANISY--------------------------------ICSRYYRAPELIF--------KSQHYTNAIDMWSMGCVI
        .||.||| .|.. ... |...                                ... .| ||| .         |...|. ..|.||.|...
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

AEMVLGEPLFPGENSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQ-KVSEDEKQ-------------KF----NQLMDLISR
 ||. |.| |                                               ... .| |.. ....             ..    .. .|||..
YEMLFGKPPF-----------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK

----VLVYAPSERPS-PLQALAHPFF
     |.. |..|.. . |.| ||.|
FGKRMLQKDPEKRITGWEQILNHPWF
Kinase 7876.AA CDK7 95-273 37 1.2e-54 143.75 In-house 59-226 (288) Show / Hide 
Range on Protein: 95-273
Range on HMM: 59-226/288
Sequence Identity: 37% (68 aa)

LDHQNIIKCKDFFETKGEKKDEVYLNLVMEFMNFPLSKVIRDKRKANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDF
. | |.|   | |  |        ..||..||   |  ||.||     ..   .|  |. .. . | |.    | |||.|| | |.|    . .||| ||
MQHDNVIGLIDIFMHKSN------IQLVFDFMDWDLEVVIKDKS---IILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMN---ENGQLKIADF

GSAKQL-IPNEANISYICSRYYRAPELIFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGENSLDQLVEIIRILGTPTRQQ
| |..   ||..  . .  |.|||||| |   ||. ..||||.||..||  |  | .||.. .|||. | ..||||| ..
GLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEE
Kinase 7876.AA DYRK 149-343 32 6.1e-53 182.19 In-house 105-320 (320) Show / Hide 
Range on Protein: 149-343
Range on HMM: 105-320/320
Sequence Identity: 32% (72 aa)

IRLYAYQMFKALSYLQSL-NICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIPNEANISYICSRYYRAPELIFKSQHYTNAIDMWSMGCVIAEMVLGE
.| .|.|....| .|... || | |.|| ||..... .  ..|..||||. .        .|| ||.||||| |   . |  |||||| ||..||...|.
VRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQ--RIYTYIQSRFYRAPEVILGCP-YCYAIDMWSLGCILAELFTGW

PLFPGENSLDQLVEIIRILGTPTRQQILMM-NPTSQEFRFPQIKSYSWSKVFEKSLQKV---------------------------SEDEKQKFNQLMDL
|||||||  |||  |. .|| |..  |     .  ..| | .   . .. ..|.. |..                           .... ... |. |.
PLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKF-FDC---FMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQ-CDDHQFKDF

ISRVLVYAPSERPSPLQALAHPFF
| ..|.. |..|..| ||| ||.|
IKKCLQWDPHKRITPSQALQHPWF
Kinase 7876.AA CDKL 147-343 36 3.1e-52 176.87 In-house 98-286 (286) Show / Hide 
Range on Protein: 147-343
Range on HMM: 98-286/286
Sequence Identity: 36% (73 aa)

EDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLI-PNEANISYICSRYYRAPELIFKSQHYTNAIDMWSMGCVIAEMVL
...| | .|  ||.... . |. |||||| |||.. |..  ..|.|||| |..|  |.|.   |   | ||||||  .   |  ..|.|. |||.|||. 
HVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNG--QVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMID

GEPLFPGENSLDQLVEIIRILG--TPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQKVSEDEKQKFNQLMDLISRVLVYAPSERPSPLQALAHPFF
|.||.||.. .|||  |.. ||  .|  |.|  .||     .||.|.     .  || ....|.        ..|..   |   |.||..  |.. ||.|
GQPLWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIE---HMEPLEKRYPNKSN------KKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 7876.AA RCK 35-272 27 1.6e-50 158.38 In-house 2-236 (298) Show / Hide 
Range on Protein: 35-272
Range on HMM: 2-236/298
Sequence Identity: 27% (71 aa)

KIIDVVGNGTFGVVYKKLDDNINFNYLKMKALLNKEQVVAVKRVFQDKRYKNRE-----REI--IERLD-HQNIIKCKDFFETKGEKKDEVYLNLVMEFM
.||. .| ||.|.| |  .             . . ..|| |.    ..... |     |||  . .|  | |||| |. .      .|.  | .|.|.|
QIIKQLGDGTYGCVMKAQN-------------KETGEIVAIKKMK--QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVI----RDNDTYQLYFVFEYM

NFPLSKVIRD-KRKANQVMRIED--IRLYAYQMFKALSYLQSLNICHRDIKPQNILVND------KDDDKRLKICDFGSAKQLIPNEANISYICSRYYRA
   |.. ..| |   .. .  .   |. . || ...|... . .. |||.|| ||....      . |. ..||.|||...    .  .  |. .|.|||
DMNLYQMMKDFKE-RRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRA

PELIFKSQHYTNAIDMWSMGCVIAEMVLGEPLFPGENSLDQLVEIIRILGTPTRQ
||.. ....|.  .|.|..||...|     ||||| . .||. .|. ..|||. .
PECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKK
Kinase 7876.AA ERK5 35-343 34 4.3e-49 169.43 In-house 2-295 (295) Show / Hide 
Range on Protein: 35-343
Range on HMM: 2-295/295
Sequence Identity: 34% (109 aa)

KIIDVVGNGTFGVVYKKLDDNINFNYLKMKALLNK-EQVVAVKRVFQDKRYKNREREIIERLDHQNIIKCKDFFETK---GEKKDEVYLNLVMEFMNFPL
|||. .||| .|||        | .   .| . |  ..|   || |       ||  |.    |.|||  .|    |   .| || ||   |.. |   |
KIIEKIGNGAYGVVCSAR-RRKNGQQVAIKKIPNAFDVVTNAKRTF-------RELKILRHFRHDNIIAIRDILMPKVPYSEMKD-VY--VVFDLMESDL

SKVIRDKRKANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIP---NEANI---SYICSRYYRAPELIFKS
 ..|     .|| . .| || . ||. . | |. | .. |||.|| |.|||.  .   ||| ||| |. |     ..  .   .|.  |.||||||.| |
HQII----HSNQPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCE---LKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSS

QHYTNAIDMWSMGCVIAEMVLGEPLFPGENSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQKVSEDEKQKFNQLMDLISRVL
. || |||.||.||.. ||.    .||| | ..||  |. .||.|  .   |.  .| .    ... |  ... ..  .  ..   .   | .||..|.|
HDYTQAIDVWSVGCIFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPH---MIQAVSAD----HVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARML

VYAPSERPSPLQALAHPFF
.. |||| .  .|| ||| 
RFEPSERITVNKALQHPFL
Kinase 7876.AA TyrKc 34-343 20 4.9e-13 -11.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-343
Range on HMM: 1-280/280
Sequence Identity: 20% (69 aa)

LKIIDVVGNGTFGVVYK-KLDDNINFNYLKMKALLNKEQVVAVKRVFQDKRYKN--REREIIERL--DHQNIIKCKDFFETKGEKKDEV----YLNLVME
.. ... |.| ||.||| ...                 . |||| .  |.  .   || .|  .|  .|.||...     ..|..         | .|||
ITLGKKLGEGAFGEVYKGTWK-----------------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVME

FMNF-PLSKVIRDKRKANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFGSAKQLIPN----EANISYI-----CSR-
.|    | . .|..|.       .|   ...|  .  .|| | |. |||.   |.||...    . ||.||| .. .       |.   |      ... 
YMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT

----YYRAPELIFKSQHYTNAIDMWSMGCVIAEMV-LGEPLFPGE----NSLDQLVEIIRILGTPTRQQILMMNPTSQEFRFPQIKSYSWSKVFEKSLQK
       ||| | .   .| . | || | .. |.  .|..  ||.     | ....| ..  . . . .     | |                       
MLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMS-----------------------

VSEDEKQKFNQLMDLISRVLVYAPSERPSPLQALAHPFF
 .         . .....   . |..||.  .   | .|
-F---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 7876.AA RCK 315-343 34 8.7e-10 26.93 In-house 270-298 (298) Show / Hide 
Range on Protein: 315-343
Range on HMM: 270-298/298
Sequence Identity: 34% (10 aa)

QLMDLISRVLVYAPSERPSPLQALAHPFF
....|.   | . |..|... ||| ||.|
DCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 7876.AA CDK7 314-343 30 8.5e-08 16.38 In-house 259-288 (288) Show / Hide 
Range on Protein: 314-343
Range on HMM: 259-288/288
Sequence Identity: 30% (9 aa)

NQLMDLISRVLVYAPSERPSPLQALAHPFF
. |.||... .   |..| .  |.| .|.|
DDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 7876.AA Pkinase_Tyr 121-195 35 3.7e-05 18.1 Pfam 84-156 (270) Show / Hide 
Range on Protein: 121-195
Range on HMM: 84-156/270
Sequence Identity: 35% (27 aa)

LVMEFMNF-PLSKVIRDKRKANQVMRIEDIRLYAYQMFKALSYLQSLNICHRDIKPQNILVNDKDDDKRLKICDFG
.|||.|    | .  |..|  .|   ..|.  ...|  |...|| | |. |||.   |.||..   ..  ||||||
IVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFG
Kinase 7876.AA CDK7 35-57 34 3.9e-05 9.14 In-house 2-24 (288) Show / Hide 
Range on Protein: 35-57
Range on HMM: 2-24/288
Sequence Identity: 34% (8 aa)

KIIDVVGNGTFGVVYKKLDDNIN
..|. .| |.|..||| .| . .
EKIKHIGEGQFATVYKACDHQTG
Kinase 7876.AA CDK 35-50 50 0.00037 9.02 In-house 2-17 (284) Show / Hide 
Range on Protein: 35-50
Range on HMM: 2-17/284
Sequence Identity: 50% (8 aa)

KIIDVVGNGTFGVVYK
.... .| ||.|||||
EKLEKIGEGTYGVVYK
Kinase 7876.AA Pkinase_Tyr 34-50 41 0.019042 8.91 Pfam 1-17 (270) Show / Hide 
Range on Protein: 34-50
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

LKIIDVVGNGTFGVVYK
.... . | | ||.|||
ITFGKKLGEGAFGEVYK
Kinase 7876.AA DYRK 35-50 43 0.121664 2.25 In-house 2-17 (320) Show / Hide 
Range on Protein: 35-50
Range on HMM: 2-17/320
Sequence Identity: 43% (7 aa)

KIIDVVGNGTFGVVYK
.|... | |.|| | |
EILEYIGKGSFGQVVK