Gene 1167 (Tetrahymena)

1167

Species: Tetrahymena
Alias: 1167, TTHERM_00851680, 1144, 150.m00059, PreTt01167, n.1167
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CMGC-Unique

Sequence

Name Sequence Type Origin Length Description Download
1167.NA RNA None 4116 None Fasta, JSON
1167.AA Protein None 979 None Fasta, JSON
1167.kin_dom Protein Kinase Domain None 135 None Fasta, JSON

Protein domain

Protein domains of 1167.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 1167.AA AGC 96-110 46 0.000169 5.97 In-house 1-15 (395) Show / Hide 
Range on Protein: 96-110
Range on HMM: 1-15/395
Sequence Identity: 46% (7 aa)

YDNNTNLGKGSFGEV
..  . .||||||.|
FEFLKVIGKGSFGKV
Kinase 1167.AA CAMK1 96-114 31 0.001233 6.37 In-house 1-19 (276) Show / Hide 
Range on Protein: 96-114
Range on HMM: 1-19/276
Sequence Identity: 31% (6 aa)

YDNNTNLGKGSFGEVKNGI
| .   .|.|.|.||. ..
YEFGKEIGRGAFSEVYLCT
Kinase 1167.AA RCK 96-117 27 0.002633 6.02 In-house 1-22 (298) Show / Hide 
Range on Protein: 96-117
Range on HMM: 1-22/298
Sequence Identity: 27% (6 aa)

YDNNTNLGKGSFGEVKNGIFID
|   ..||.|..|.|  .. ..
YQIIKQLGDGTYGCVMKAQNKE
Kinase 1167.AA CAMK 101-114 64 0.004588 4.92 In-house 1-14 (425) Show / Hide 
Range on Protein: 101-114
Range on HMM: 1-14/425
Sequence Identity: 64% (9 aa)

NLGKGSFGEVKNGI
 ||.||||.|| .|
TLGRGSFGKVKLCI
Kinase 1167.AA CMGC 96-110 33 0.015286 3.13 In-house 1-15 (513) Show / Hide 
Range on Protein: 96-110
Range on HMM: 1-15/513
Sequence Identity: 33% (5 aa)

YDNNTNLGKGSFGEV
|..   .|.|..|.|
YEIIKKIGEGTYGVV
Kinase 1167.AA Ciliate-B1 96-110 33 0.018887 4.53 In-house 1-15 (290) Show / Hide 
Range on Protein: 96-110
Range on HMM: 1-15/290
Sequence Identity: 33% (5 aa)

YDNNTNLGKGSFGEV
| .|  .|.|....|
YQQNNVIGQGAISQV
Kinase 1167.AA Ciliate-E2-Unclassified 96-111 37 0.049718 2.86 In-house 1-16 (352) Show / Hide 
Range on Protein: 96-111
Range on HMM: 1-16/352
Sequence Identity: 37% (6 aa)

YDNNTNLGKGSFGEVK
|  .  .|.|.||.|.
YKIIKQIGQGGFGKVY
Kinase 1167.AA Ciliate-E2a 96-111 43 0.049884 1.79 In-house 1-16 (275) Show / Hide 
Range on Protein: 96-111
Range on HMM: 1-16/275
Sequence Identity: 43% (7 aa)

YDNNTNLGKGSFGEVK
|. .  .|||.|| |.
YKFIKKIGKGNFGSVY
Kinase 1167.AA Ciliate-E2 96-112 27 0.107673 1.57 In-house 1-22 (365) Show / Hide 
Range on Protein: 96-112
Range on HMM: 1-22/365
Sequence Identity: 27% (6 aa)

YDNNTNLGKGSFG-----EVKN
|. .  .|.|.||     .|..
YKFIKKIGQGNFGSVYKCKVWK
Kinase 1167.AA Pkinase 96-114 36 3.583792 1.69 Pfam 1-19 (293) Show / Hide 
Range on Protein: 96-114
Range on HMM: 1-19/293
Sequence Identity: 36% (7 aa)

YDNNTNLGKGSFGEVKNGI
|     .|.||||.|. ..
YHIGRKIGSGSFGCVYKCH
Kinase 1167.AA CMGC-Unique 275-426 34 3.5e-68 232.84 In-house 143-352 (352) Show / Hide 
Range on Protein: 275-426
Range on HMM: 143-352/352
Sequence Identity: 34% (73 aa)

DIIQAMQFGRQILQG--SSVGTINYMAPEQVIGIYNQDSNYKLS---YNNKIDLWAAGAIIHEMITGIQLFP----------------------GNYPKN
|| |  |.|  | |   .......||.|||...||.|....|||   |..|.|.|.||.|.||||.|.|||.                      ||..||
DIQQFQQQGNKICQPHFGNMRSYQYMKPEQPCEIYMQYNHHKLSYRIYWKKMDMWSAGCIFHEMIQGKQLFNNPNLDNNNNNNNNNNNNNNNFHGNNNKN

VSKDIVKFGSYKSKWEKSQNID--LNSIPETMMAEQRKFIGFYLPWQRVNNKQ-VAYFIDN----------------------------LLKCKPEERFS
|...||||.....||...||||  .|..||.||.....||.|..||....||| ..||..|                            ..||.|..|..
VIHNIVKFNGNHFKWDNNQNIDNNFNNWPEMMMQQLMQFINFPVPWEKSFNKQRNHYFKANHNIIIKSKVERDFNGANLPTDAYNLMCQMMKCNPHKRIM

ADQALQEINK
|.||||..  
ANQALQHKFF
Kinase 1167.AA CMGC 292-422 18 3.4e-18 55.54 In-house 286-509 (513) Show / Hide 
Range on Protein: 292-422
Range on HMM: 286-509/513
Sequence Identity: 18% (41 aa)

VGTINYMAPEQVIGI--YNQDSNYKLSYNNKIDLWAAGAIIHEMITG--------IQLFPGNYP------------KNVSKDIVKFGSY-----------
| |  | |||  .|   |..  ||.  |. .|| |..| |. ||.||          ||||.                  | .  .|.            
VVTRWYRAPEILLGWKHYTNH-NYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHF

-----KSKWE-KSQNIDLNSIPE-----------TMMAEQRKFIGFYLPWQRVNN--------------------------------------------K
     . .|  .... . |  |.           .  | . ..... .||.. ..                                            .
NFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDP

QVAYFIDNLLKCKPEERFSADQALQ
|   .....|.. |..| .|.||||
QAIDLLKKMLQYDPDKRITAEQALQ
S_TKc 1167.AA S_TKc 161-428 18 4.6e-16 58.64 SMART 1-231 (231) Show / Hide 
Range on Protein: 161-428
Range on HMM: 1-231/231
Sequence Identity: 18% (59 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQDKENKYYENEINICERIMKFQKENKQYNSNEMNLIEIFEVIQTENCAYIVMECCEL
|.    .|||.|| |.|.  |.  .|.|.  ||| |.           .  ..||.|...             .  |.. ...|.|. .. |.|||.|. 
YEILRKIGKGAFGKVYKCRHKK--TGRIV--AIKIIK-----------EHIRREIQILKK-------------HHPNIVKLYDVFQD-DHLYMVMEYCDG

N-LEAYKFIQVNRR------IDIIQAMQFGRQILQG-------------------------------------SSVGTINYMAPEQVIGIYNQDSNYKLS
.  . ...|. ..|      ..  .|  . .||...                                     . .|| .||||| .            .
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVL------------G

YNN-KIDLWAAGAIIHEMITGIQLFPGNYPKNVSKDIVKFGSYKSKWEKSQNIDLNSIPETMMAEQRKFIGFYLPWQRVNNKQVAYFIDNLLKCKPEERF
|.  |.| |. | |. ||..|  .||     ..  ....                                          ...  ||...|.  ||.| 
YGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------------------------------SPEAKDFIRKCLQKDPEKRP

SADQALQEI-----NKIL
.| .|||.         .
TA-EALQDEWDIKCHPWF
Kinase 1167.AA Ciliate-B1 290-355 44 1.6e-13 43.83 In-house 187-246 (290) Show / Hide 
Range on Protein: 290-355
Range on HMM: 187-246/290
Sequence Identity: 44% (31 aa)

SSVGTINYMAPEQVIGIY-NQDSNYKLSYNNKIDLWAAGAIIHEMITGIQLFP--GNYPKNVSKDIVKF
| ||||||||||  | .. ||      .| .|.| |. | |..| ||. |||.  ||  ..|.  | .|
SCVGTINYMAPE--I-LNFNQ------QYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNF
Kinase 1167.AA Ciliate-E2 290-422 15 1.1e-12 39.81 In-house 246-361 (365) Show / Hide 
Range on Protein: 290-422
Range on HMM: 246-361/365
Sequence Identity: 15% (27 aa)

SSVGTINYMAPEQVI--GIYNQDSNYKLSYNNKIDLWAAGAIIHEMITGIQLFPGNYPKNVSKDIVKFGSYKSKWEKSQNIDLNSIPETMMAEQRKFIGF
. .|| .||||| .   ...||  . .  |. |.|.|..| |..||..|   |                                               
TICGTPGYMAPEILNGKKYDNQ--QKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------------------------------------------

YLPWQRVNNK-----------------------------QVAYFIDN----LLKCKPEERFS-ADQALQ
    |. . .                             ..  .| .    .|...||.|.. ..|.|.
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 1167.AA AGC 292-343 30 8.7e-11 22.6 In-house 266-308 (395) Show / Hide 
Range on Protein: 292-343
Range on HMM: 266-308/395
Sequence Identity: 30% (17 aa)

VG--TINYMAPEQVIGIYNQDSNYKLSYNNKIDLWA--AGAIIHEMITGIQLFPGN
.|  | .||||| .             |.   | |.   |... ||.||.  | |.
CGPCTPEYMAPEIL-------------YGKACDWWSFGLGCLMYEMLTGYPPFYGD
Kinase 1167.AA Ciliate-B1 161-259 29 1.7e-10 33.1 In-house 1-100 (290) Show / Hide 
Range on Protein: 161-259
Range on HMM: 1-100/290
Sequence Identity: 29% (30 aa)

YDNNSNLGKGSFGDVKKG-FFKDPISGKIYPAAIKLISRQQCLQQDKENKYYENEINICERIMKFQKEN--KQYNSNEMNLIEIFEVIQTENCAYIVMEC
| .|  .|.|... | .| |  . . ....  |.|.|. |  .   ..||||..|..|   . |  ..|      |   .   |..|||.   .||.|| 
YQQNNVIGQGAISQVFYGQFCQNQQCQQEV--AVKKITKQTQDNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEY

CE
||
CE
Kinase 1167.AA CAMK 166-259 18 2.2e-09 25.66 In-house 1-143 (425) Show / Hide 
Range on Protein: 166-259
Range on HMM: 1-143/425
Sequence Identity: 18% (28 aa)

NLGKGSFGDVKKGFFKDPISGKI--------YPAAIKLISRQQCLQ------------------------QDKENKYYENEINICERIMKFQKENKQYNS
 ||.|||| ||... |     .            ||| |....                           ..|  |  ..||.|. .. .  .     . 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-----KL

NEMNLIEIFEVIQ------------TENC--------AYIVM---ECCE
.  |.| ..||..            | ..         |.||   | |.
DHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCS
Kinase 1167.AA Pkinase 292-342 37 4.3e-08 29.69 Pfam 172-214 (293) Show / Hide 
Range on Protein: 292-342
Range on HMM: 172-214/293
Sequence Identity: 37% (19 aa)

VGTINYMAPEQVIGIYNQDSNYKLSYNNKIDLWAAGAIIHEMITGIQLFPG
.||..||||| .             |  |.| |..| |..||..|  .|||
CGTPWYMAPEVIR--------GGQYYGPKVDMWSCGCILYEMLCGRPPFPG
Kinase 1167.AA Ciliate-E2-Unclassified 280-422 22 4.9e-08 24.0 In-house 211-348 (352) Show / Hide 
Range on Protein: 280-422
Range on HMM: 211-348/352
Sequence Identity: 22% (36 aa)

MQFGRQILQGSSVGTINYM----APEQVIG-IYNQDSNYKLSYNNKIDLWAAGAIIHEMITGIQLFPGNY---PKNVSKDIVKF-----GSYKSKWEKSQ
||. .| .. . .||.|||    |||   |  |.. .        |.| |. | |..||..|   |..|     ..... .. .       |. . .| .
MQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQLYQNIKQKNI

NIDLNS---IPETMMAEQRKFIGFYLPWQRVNNKQVAYFIDNLLKCKPEERFSADQALQ
...  .   || .   |.  ||                ..  .|| .|..| ...|.|.
QFPKFPWQQIPKHWSPEAKDFIN--------------DLLQKMLKKNPNKRITFEQILN
Kinase 1167.AA CAMK1 161-217 27 8.8e-07 15.67 In-house 1-58 (276) Show / Hide 
Range on Protein: 161-217
Range on HMM: 1-58/276
Sequence Identity: 27% (17 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIY-PAAIKLIS-RQQCLQ---QDKENKYYENEINI
| . . .|.|.|..|...  |. .   .. . ||| |. ...  .   | |  .. ||||.|
YEFGKEIGRGAFSEVYLCTHKETQ-T-NGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEI
Kinase 1167.AA Ciliate-E2a 292-342 30 2e-06 14.7 In-house 171-218 (275) Show / Hide 
Range on Protein: 292-342
Range on HMM: 171-218/275
Sequence Identity: 30% (16 aa)

VGTINYMAPEQVIGIYNQDSN-YKLSYNNKIDLWAAGAIIHEMITGIQLFPG
.||  |.|||    ..|      . .|  | |.| .|.|.. ...| ..|.|
CGTPGYVAPE----VLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKG
Kinase 1167.AA CAMK1 402-422 33 3e-06 14.21 In-house 252-272 (276) Show / Hide 
Range on Protein: 402-422
Range on HMM: 252-272/276
Sequence Identity: 33% (7 aa)

FIDNLLKCKPEERFSADQALQ
|| ..|.. |..|....|.|.
FIKHMLEVDPKKRYTCEQCLN
Kinase 1167.AA Ciliate-E2a 161-259 33 7e-06 13.41 In-house 1-82 (275) Show / Hide 
Range on Protein: 161-259
Range on HMM: 1-82/275
Sequence Identity: 33% (33 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQDKENKYYENEINICERIMKFQKENKQYNSNEMNLIEIFEVIQTENCAYIVMECCE
|. .  .|||.|| |..   |.   || .  |.| ...    ||.|...| .|||||  ..            .  |.| ..|| ..||  |.||| ||
YKFIKKIGKGNFGSVYLAQHKQT--GKQF--AMKKFIK-KMYQQKKGKEYFMNEINIMRQL------------DHPNIIKLYEVYEDENNYYLVMEYCE
Kinase 1167.AA CAMK 291-422 19 1e-05 13.6 In-house 279-421 (425) Show / Hide 
Range on Protein: 291-422
Range on HMM: 279-421/425
Sequence Identity: 19% (31 aa)

SVGTINYMA-PEQVIG-IYNQDSNY-----KLSYNNKIDLWAAGAIIHEMITGIQLFPGNYPKNVSKDIVKFGSYKSKWEKSQNIDLNSIPETMMAEQRK
..||  ||| || . |    .   .     |  |. |.| |..| |   | .|   | | . ..  . . .    .         ... . |  |. .  
FCGTPEYMAAPEVLNGKGHCNMQ-NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E----W------IGMNDYELFEKIMKGKYD

FIGFYLP----------WQRVNNK-------QVAYFIDNLLKCKPEERFSADQALQ
|. .|..          | .. .        ..  .| ..|.  ||.|....|.|.
FPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 1167.AA RCK 317-343 44 2e-05 12.83 In-house 191-217 (298) Show / Hide 
Range on Protein: 317-343
Range on HMM: 191-217/298
Sequence Identity: 44% (12 aa)

YNNKIDLWAAGAIIHEMITGIQLFPGN
|| ..|.|| |.|. |  .   ||||.
YNSPMDIWAVGCIMYELYMLRPLFPGS
Kinase 1167.AA TyrKc 161-424 12 9.6e-05 -145.91 SMART 1-280 (280) Show / Hide 
Range on Protein: 161-424
Range on HMM: 1-280/280
Sequence Identity: 12% (43 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQDKENKYYENEINICERIMKFQKENK--QYN-SNEMNLIEIFEVIQTE-------NC
   .  || | || | ||  |       .. |.| .                        .. | .| .       .  |.. .. |. ..         
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP

AYIVMECCELNLEAYKFIQVNRR-IDIIQAMQFGRQILQG----SSVGTI-------------NY--------MAPEQVIG--------IYNQ----DSN
 .|||| ...     .... .|. .   .  .|  || .|    .| . |             |.        .. .   .         | .    ...
LMIVMEYMPH-GDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

Y-------------KLSYNNKIDLWAAGAIIHEMITGIQLFPGN------YPKNVSKDIVKFGSYKSKWEK----SQNIDLNSIPETMMAEQRKFIGFYL
.             .  .. | | |. |  . |. |  |  . .       .. | ... . | .  . .     |                     |  
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ-GYRMPQPPNDYPMS---------------------F--

PWQRVNNKQVAYFIDNLLKC---KPEERFSADQALQEI
          .   .  ..|   .||.| .  .  ...
------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 1167.AA RCK 237-262 35 0.000238 9.39 In-house 59-86 (298) Show / Hide 
Range on Protein: 237-262
Range on HMM: 59-86/298
Sequence Identity: 35% (10 aa)

NLIEIFEVIQTEN--CAYIVMECCELNL
|.|...|||. ..    |.|.|... ||
NIIKLKEVIRDNDTYQLYFVFEYMDMNL
Kinase 1167.AA CMGC 161-289 15 0.000515 8.06 In-house 1-192 (513) Show / Hide 
Range on Protein: 161-289
Range on HMM: 1-192/513
Sequence Identity: 15% (30 aa)

YDNNSNLGKGSFGDVKKGFFKDP------------ISGKIYPAAIKLISRQQCLQQDKE---NKYYENEINICERIM--KFQKENKQYNS---------N
|.. . .|.|..| | |.. |.              ...|.  ||| |....  . ..     |   . . . |  .  ...|.... |.         .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIV--AIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDP-NWQRRDDPDNKH

EMNLIEIFEVIQTEN-----------------CAYIVMECCELNLEAYKFIQVNRR----------------------------IDIIQAMQFGRQILQG
. |.. ........|                 . |.|.|... .|  |..|. |..                            . | .   . .|||.|
HNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDL--YQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRG
Kinase 1167.AA Ciliate-E2-Unclassified 161-259 23 0.000516 9.84 In-house 1-104 (352) Show / Hide 
Range on Protein: 161-259
Range on HMM: 1-104/352
Sequence Identity: 23% (26 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQDKENKYYENEINICERIMKFQKENKQ-----------YNSNEMNLIEIFEVIQTEN
|  .  .|.|.||.|.|   |.    | . .|.| .. .|   | . ..   ...|. ..... .| . |           .|..  ...  |.. |...
YKIIKQIGQGGFGKVYKCQHKK---QK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

CAYIVMECCE
. ||||| ||
NIYIVMEYCE
Kinase 1167.AA Pkinase 161-289 22 0.000654 14.91 Pfam 1-120 (293) Show / Hide 
Range on Protein: 161-289
Range on HMM: 1-120/293
Sequence Identity: 22% (31 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQDKENKYYEN--EINICERIMKFQKENKQYNSNEMNLIEIFEVIQTENCAYIVMECC
|   . .|.|||| |.|.  ..  .|||.  |.| |...   . ......  .  || |  |.               | ...... ....  |.|||.|
YHIGRKIGSGSFGCVYKC--HHKGTGKIV--AVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLN------------HPNIVRLYDWFEDKDHIYMVMEYC

ELNL---EAYKFIQ--VNRRI--DIIQAMQFGRQILQG
|  |   . . .|.   ....  .  ..  . .|||.|
EGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRG
Kinase 1167.AA RCK 161-178 38 0.000729 7.82 In-house 1-18 (298) Show / Hide 
Range on Protein: 161-178
Range on HMM: 1-18/298
Sequence Identity: 38% (7 aa)

YDNNSNLGKGSFGDVKKG
|   ..||.|..|.| |.
YQIIKQLGDGTYGCVMKA
Kinase 1167.AA AGC 161-175 46 0.001459 3.49 In-house 1-15 (395) Show / Hide 
Range on Protein: 161-175
Range on HMM: 1-15/395
Sequence Identity: 46% (7 aa)

YDNNSNLGKGSFGDV
..    .|||||| |
FEFLKVIGKGSFGKV
Kinase 1167.AA Ciliate-E2 161-259 25 0.003348 6.82 In-house 1-117 (365) Show / Hide 
Range on Protein: 161-259
Range on HMM: 1-117/365
Sequence Identity: 25% (31 aa)

YDNNSNLGKGSFGDVKKGFFKDPISGKIYPAAIKLISRQQCLQQD-----KENKYYENEINICERIMKFQKENKQY-----------------NSNEMNL
|. .  .|.|.||.|.|.  |.   .| .  |||.|  |   |.        .|.|. .|..   |  . .|....                 . |  |.
YKFIKKIGQGNFGSVYKC--KVWKVQKQF--AIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNI

IEIFEVIQ--TENCAYIVMECCE
|...|. |  ..|. |.||| |.
IKMYECFQEKDDNNIYLVMEYCQ
Kinase 1167.AA Ciliate-E2a 406-422 41 0.008057 4.16 In-house 255-271 (275) Show / Hide 
Range on Protein: 406-422
Range on HMM: 255-271/275
Sequence Identity: 41% (7 aa)

LLKCKPEERFSADQALQ
.|.. |..|..| |||.
MLEKDPKKRITAQQALN
Kinase 1167.AA Pkinase 402-424 36 0.112151 7.01 Pfam 269-293 (293) Show / Hide 
Range on Protein: 402-424
Range on HMM: 269-293/293
Sequence Identity: 36% (9 aa)

FIDNLLKCKPEERFSADQALQE--I
||...|. .|..| .|.|.||   .
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase 1167.AA Ciliate-E2 847-959 23 1.4e-12 39.51 In-house 253-359 (365) Show / Hide 
Range on Protein: 847-959
Range on HMM: 253-359/365
Sequence Identity: 23% (32 aa)

YMSPQQLQFQK---------STFEDDIWALGAIFHQILTLAPLFQSIPKVKDLINKYSENYSDMYGEAQAYIQANEEGKKKFS-PSIQRASAL-------
||.|. |. .|          ... |||.|| |... |.  | |                           .| ....| .|. |  |   ..       
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------------------QQQIKQCKIDFPCPEWQKD-TQCIQCKWK

LEKIPNQDIANLINK----MLSKDPTKRPK-IQDI
  |   |.  .||.|    || ||| ||.  ...|
SWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 1167.AA Pkinase 847-963 15 5.8e-07 25.71 Pfam 177-293 (293) Show / Hide 
Range on Protein: 847-963
Range on HMM: 177-293/293
Sequence Identity: 15% (20 aa)

YMSPQQLQ-FQKSTFEDDIWALGAIFHQILTLAPLFQSI------------PKVKDLINKYSENYS-DMYGEAQAYIQANEEGKKKFSPSIQRASALLEK
||.|  ..  |. . . |.|..| |... |.  |.|..              .... ...... .. ... .   ..   .           .   .. .
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----------F-HWTF-H

IPNQDIANLINKMLSKDPTKRPKIQDINNE--L
  ...   .|...| |||.||| ...| .   .
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 1167.AA CMGC 863-959 14 8e-06 14.17 In-house 317-507 (513) Show / Hide 
Range on Protein: 863-959
Range on HMM: 317-507/513
Sequence Identity: 14% (28 aa)

DIWALGAIFHQILT--------LAPLFQ--------------------SIPKVKDLIN-------------KYSENYSDMYG------------------
|.|..| ||  ..|        . |||.                     | ||   ..             |..|.. .| .                  
DMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLPWYNKFPKKWNWQTMTN

----EAQAYIQANEEGKKKFSPSIQRASALLEK-------------------------------IPNQDIANLINKMLSKDPTKRPKIQDI
     |. ||| |   ...  .....    . .                                 ...  .|..|||  ||.||......
HWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQA
Kinase 1167.AA CAMK 936-959 45 3.3e-05 11.95 In-house 396-419 (425) Show / Hide 
Range on Protein: 936-959
Range on HMM: 396-419/425
Sequence Identity: 45% (11 aa)

QDIANLINKMLSKDPTKRPKIQDI
|.  .||.||| .||.||..|...
QECKDLIRKMLQVDPEKRMTIEQC
Kinase 1167.AA Ciliate-B1 929-964 21 0.000103 12.56 In-house 250-290 (290) Show / Hide 
Range on Protein: 929-964
Range on HMM: 250-290/290
Sequence Identity: 21% (9 aa)

LLEKIPNQDIANLINK-----MLSKDPTKRPKIQDINNELN
.. ...  .| ..|        |..|| .|..|..| ..| 
DYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM
Kinase 1167.AA AGC 936-959 29 0.000157 6.05 In-house 356-389 (395) Show / Hide 
Range on Protein: 936-959
Range on HMM: 356-389/395
Sequence Identity: 29% (10 aa)

QDIANLINKMLSKDPTKRPK----------IQDI
..  .||.|.| |||.||.           ...|
PEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI
Kinase 1167.AA RCK 863-881 52 0.000286 9.13 In-house 196-214 (298) Show / Hide 
Range on Protein: 863-881
Range on HMM: 196-214/298
Sequence Identity: 52% (10 aa)

DIWALGAIFHQILTLAPLF
||||.|.|.  . .| |||
DIWAVGCIMYELYMLRPLF
Kinase 1167.AA Ciliate-E2a 863-882 40 0.000906 7.0 In-house 198-217 (275) Show / Hide 
Range on Protein: 863-882
Range on HMM: 198-217/275
Sequence Identity: 40% (8 aa)

DIWALGAIFHQILTLAPLFQ
|.| .|.||.  |.  |.|.
DMWSCGVIFYILLCGKPPFK
Kinase 1167.AA Ciliate-E2a 940-959 50 0.000942 6.95 In-house 250-269 (275) Show / Hide 
Range on Protein: 940-959
Range on HMM: 250-269/275
Sequence Identity: 50% (10 aa)

NLINKMLSKDPTKRPKIQDI
.|. ||| ||| ||...|..
DLMKKMLEKDPKKRITAQQA
Kinase 1167.AA Ciliate-E2-Unclassified 795-959 16 0.001332 8.39 In-house 156-346 (352) Show / Hide 
Range on Protein: 795-959
Range on HMM: 156-346/352
Sequence Identity: 16% (36 aa)

LQSLHENN-IYHGQLNVKNISFCQKQQ--QFFLNYYSL--FENHPTYHKDGF----------------YFEQSYM----SPQQLQFQKST----FEDDIW
|..||..| | |  .   || | ....  .  .  ...  . . . . . ..                    .||    .|  || |.      .. |||
LEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIW

ALGAIFHQILTLAPLFQSIPKVK---------------DLINKYSEN------YS------DMYGEAQAYIQANEEGKKKFSPSIQRASALLEKIPNQDI
.|| |....|.  . |..  . .                |...  ..      ..      .   ||.  |.                            
SLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN----------------------------

ANLINKMLSKDPTKRPKIQDI
 .|. ||| |.| ||. ...|
-DLLQKMLKKNPNKRITFEQI
Kinase 1167.AA CAMK1 940-959 35 0.006837 4.17 In-house 251-270 (276) Show / Hide 
Range on Protein: 940-959
Range on HMM: 251-270/276
Sequence Identity: 35% (7 aa)

NLINKMLSKDPTKRPKIQDI
..|..|| .||.||. ....
DFIKHMLEVDPKKRYTCEQC
Kinase 1167.AA CMGC-Unique 863-881 42 0.011803 4.59 In-house 195-213 (352) Show / Hide 
Range on Protein: 863-881
Range on HMM: 195-213/352
Sequence Identity: 42% (8 aa)

DIWALGAIFHQILTLAPLF
|.|..|.|||  ..   ||
DMWSAGCIFHEMIQGKQLF
Kinase 1167.AA RCK 935-954 50 0.083282 1.18 In-house 268-287 (298) Show / Hide 
Range on Protein: 935-954
Range on HMM: 268-287/298
Sequence Identity: 50% (10 aa)

NQDIANLINKMLSKDPTKRP
.||  .|..|||  || ||.
SQDCIELMEKMLQWDPQKRI
Kinase 1167.AA Ciliate-E2 787-813 21 0.290189 0.07 In-house 147-192 (365) Show / Hide 
Range on Protein: 787-813
Range on HMM: 147-192/365
Sequence Identity: 21% (10 aa)

ICSLIAQQL------------------QSLHENN-IYHGQLNVKNI
|. ...|.|                  ..||..| | |  .   ||
IKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENI