Gene 28298 (Tetrahymena)

28298

Species: Tetrahymena
Alias: PreTt28298, 751, TTHERM_01276350, 304.m00018, 28298
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
28298.AA Protein None 302 None Fasta, JSON
28298.kin_dom Protein Kinase Domain None 264 None Fasta, JSON
28298.NA RNA None 909 None Fasta, JSON

Protein domain

Protein domains of 28298.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28298.AA CK2 94-283 36 2.5e-108 324.6 In-house 107-288 (288) Show / Hide 
Range on Protein: 94-283
Range on HMM: 107-288/288
Sequence Identity: 36% (69 aa)

TIYQAHKIGVIHRDIKSANIIINHEKRVLKVIDWGLSDIYFPYSFNFCKIGTVNYKAPELILTDSYHINITPAVDIWASGVIIFQMMINSVPLIKGHNSY
.....|..|..|||.|..||.|.||||.|..|||||...|.|............||.|||.....|..   ...|.|..|.....|.....|...||..|
ALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYD---YSLDMWSLGCMFASMIFKKEPFFHGHDNY

TALLDIIKIFGYKDVMRLSSWSGIPLNPQIYKEIQENKIYTEKGKGLKQLIDQDNVKYADPLGLDLIDKMLKILPNERISAKEALDHPYF
..|..|.|..|..|........||.|.||.....|..|.     |.....|.|.|...|.| ..|..||||.....|||.||||..||||
DQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKK-----KPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase 28298.AA CMGC 99-283 20 4.7e-49 158.81 In-house 199-513 (513) Show / Hide 
Range on Protein: 99-283
Range on HMM: 199-513/513
Sequence Identity: 20% (64 aa)

HKIG--VIHRDIKSANIIINHEKRV-------------------LKVIDWGLSDIYFPYS----------------------FNFCKIGTVNYKAPELIL
|. .  .||||.| .|| |||....                   ||..|.||. .| |.|                      ..   . |  |.|||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

TDSYH------INITPAVDIWASGVIIFQMMIN-------SVPLIKGHNS-----------YTALLDIIKIFG------------------YKDVMRLSS
 ...        . |...|.|. | |.. |. .         || .||..           .  |  |.|..|                   .. .  ..
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

WSGIPLNPQ---------IYKEIQENKIYT------EKGKGLKQLIDQDNV------------------------------KYADPLGLDLIDKMLKILP
  . ...|.         ...| . |.|         ..| .|.|.  ..                               | .||...||..|||.. |
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

NERISAKEALDHPYF
..||.|..||.||||
DKRITAEQALQHPYF
Kinase 28298.AA CK2 20-93 46 4.6e-39 113.74 In-house 1-75 (288) Show / Hide 
Range on Protein: 20-93
Range on HMM: 1-75/288
Sequence Identity: 46% (35 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEK-ILIKILRPNKIEKVQREISILTKVNSIENVPKFYGITVDKYYQVPSL
| |..|.|.||.|.|. |.|..|| .  |.||||.|.|..|..|||.||...|...|..|.|.|..|.|..||.|
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPAL
S_TKc 28298.AA S_TKc 20-283 20 1.1e-33 119.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-283
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEKILIKILRPNKIEKVQREISILTKVNSIENVPKFYGITV-------------------DKYYQVPS------LT
| .. |.|.| |. ||....|.   ..  |||..    |...|||.|| |    .|. |.|.. .                   |   . ..      ..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

IYQA--------------HKIGVIHRDIKSANIIINHEKRVLKVIDWGLSDIYFPYSFNFCKIGTVNYKAPELILTDSYHINITP-AVDIWASGVIIFQM
  .|              |. |.||||.| .|| ...   ..|..| ||. ..         .|| .| |||..         .. ..|.|. |.|.. |
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEM

MINSVPLIKGHNSYTALLDIIKIFGYKDVMRLSSWSGIPLNPQIYKEIQENKIYTEKGKGLKQLIDQDNVKYADPLGLDLIDKMLKILPNERISAKEALD
.    |       . .....|.                                                   .| ..|.|.|.|.  |..|..| ||| 
LCGYPPFP----QMQMMFKKIG---------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------HPYF
       ||.|
DEWDIKCHPWF
Kinase 28298.AA Ciliate-E2 99-283 22 8.6e-30 99.44 In-house 177-365 (365) Show / Hide 
Range on Protein: 99-283
Range on HMM: 177-365/365
Sequence Identity: 22% (53 aa)

HKIG-VIHRDIKSANIIINHEKRVLKVIDWGLSDIYFP-----------YSFNFCK----------------------IGTVNYKAPELILTDSY-----
|. . .||||||  ||..      .|.||.||| .| .           . . | |                      .|| .|.||| .   .|     
HSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQK

HINITPAVDIWASGVIIFQMMINSVPLIKGHNSYTALLDIIKIFGYKDVMRLSSWSGIPLNPQIYKEIQENKIY---TEKGKGLKQLIDQDNVKY-----
.   . ..|||. |||...|. .  |                                      ...|...||     |..|  .| ..   .|.     
QKGYDYKCDIWSLGVILYEMLFGKPPF-------------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKWKSWKK

ADPLGLDLIDK----MLKILPNERIS-AKEALDHPYF
 .. . ||| |    ||.  |..||. ....|.||.|
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 28298.AA Ciliate-E2-Unclassified 95-283 23 3.8e-22 73.63 In-house 156-352 (352) Show / Hide 
Range on Protein: 95-283
Range on HMM: 156-352/352
Sequence Identity: 23% (51 aa)

IYQAHKIG-VIHRDIKSANIIINHEKR--VLKVIDWGLS---------DIYF--------PYSFNFCKIGTVNYK----APELILTDSYH----INITPA
. . |. . .||||||  ||... ...   .|.||.|.|         | ..        ..     ..|| ||.    |||..    |     .    .
LEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAY----K

VDIWASGVIIFQMMINSVPLIKGHNSYTALLDIIKIFGYKDVMRLSSWSGIPLNPQIYKEIQENKIYTEKGKGLKQL---IDQDNVKYADPLGLDLIDKM
.|||. |||...|. .  .  .. |..    .|...    .                |.......|.  . .  |.    |...  . |  .  ||. ||
CDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWI-N-N---------------AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKM

LKILPNERISAKEALDHPYF
||  ||.||.....| ||.|
LKKNPNKRITFEQILNHPWF
Kinase 28298.AA Pkinase 99-185 33 6.5e-21 75.03 Pfam 125-211 (293) Show / Hide 
Range on Protein: 99-185
Range on HMM: 125-211/293
Sequence Identity: 33% (31 aa)

HKIGVIHRDIKSANIIINHEKRV---LKVIDWGLSDI--YFPYSFNFCKIGTVNYKAPELILTDSYHINITPAVDIWASGVIIFQMMINSVP
|. |.||||.|..|| |...  .   .|..|.||.    | ..| .    || .| |||.|.    .  ..|.||.|. |.|...|.    |
HSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase 28298.AA CDK 148-283 25 6.3e-19 57.03 In-house 185-284 (284) Show / Hide 
Range on Protein: 148-283
Range on HMM: 185-284/284
Sequence Identity: 25% (36 aa)

YKAPELIL-TDSY-HINITPAVDIWASGVIIFQMMI--NSVPLIKGHNSYTALLDIIKIFGYKDVMRLSSWSGIPLNPQIYKEIQENKIYTEKGKGLKQL
| |||| | .  |     ....|.|. | |.  |.   .  ||  | .    |  |..|.|  .     ...  |.                        
YRAPELLLGSKHYSG---GTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------

IDQDNVKYADPLGLDLIDKMLKILPNERISAKEALDHPYF
              ||..|||   |. ||||..||.||||
--------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 28298.AA CAMK 99-177 20 7.5e-18 53.43 In-house 196-325 (425) Show / Hide 
Range on Protein: 99-177
Range on HMM: 196-325/425
Sequence Identity: 20% (27 aa)

HKIGVIHRDIKSANIIINHEK----------------RVLKVIDWGLSDIYFPYSFNF------------------------CKIGTVNYKA-PELIL--
|. ...|||.|  || ... .                  .|.||.|.. ...| . ||                           ||  | | ||...  
HSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

-TDSYHIN--------ITPAVDIWASGVIIF
 ....  |        ..|..|.|. ||| .
GHCNMQ-NATDEEKPYYGPKCDMWSCGVILY
Kinase 28298.AA CAMK1 20-70 30 8.3e-14 36.46 In-house 1-62 (276) Show / Hide 
Range on Protein: 20-70
Range on HMM: 1-62/276
Sequence Identity: 30% (19 aa)

YLVGSKLGSGKFSDVYLGYNKSN--NYE----KILI--KILRPNKI---EKVQREISILTKV
| .|...|.| ||.|||. .|..  |..    |...  | .  ..    |....||.|..||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKV
Kinase 28298.AA CAMKL 99-175 35 8.5e-14 40.26 In-house 144-225 (297) Show / Hide 
Range on Protein: 99-175
Range on HMM: 144-225/297
Sequence Identity: 35% (30 aa)

HKIGVIHRDIKSANIIINHEKR-VLKVIDWGLSDIYFP-----YSFNFCKIGTVNYKAPELILT--DSYHINITPAVDIWASGVI
|. |..|||||  || . . .. ..|.|| |.| .| |       .     |. .| |||...   ..|.    |.||||. |||
HSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYD---GPKVDIWSCGVI
Kinase 28298.AA CAMK 25-88 17 9.3e-13 36.72 In-house 1-133 (425) Show / Hide 
Range on Protein: 25-88
Range on HMM: 1-133/425
Sequence Identity: 17% (23 aa)

KLGSGKFSDVYLGYNKSNN-----------YEKILIKILR-------------------------------PNKIEKVQREISILTKVN------SIENV
.||.| |. |.|...|...            .|  |||.                                |.. ..|.|||.|. |..      . .|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

PKFYGITVD---------------------KYY
 |.| .  |                     ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMY
Kinase 28298.AA Ciliate-E2a 245-283 35 1.9e-12 32.98 In-house 236-275 (275) Show / Hide 
Range on Protein: 245-283
Range on HMM: 236-275/275
Sequence Identity: 35% (14 aa)

DQDN-VKYADPLGLDLIDKMLKILPNERISAKEALDHPYF
.. .  .. .    ||. |||.  |..||.|..||.||.|
NCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 28298.AA CMGC 20-86 20 9.6e-11 30.59 In-house 1-110 (513) Show / Hide 
Range on Protein: 20-86
Range on HMM: 1-110/513
Sequence Identity: 20% (23 aa)

YLVGSKLGSGKFSDVYLGYNKSNN-------------YEKILIKILRPNKIEKVQ---------------REISILTKVN----------------SIEN
| . .|.|.| .. || ...| .|              |.. ||... .. .. |               |||.|| ..|                  .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VPKFYGITVDK
. | | | ..|
IVKLYDIFYHK
Kinase 28298.AA CAMKL 20-71 28 1.8e-10 29.5 In-house 1-70 (297) Show / Hide 
Range on Protein: 20-71
Range on HMM: 1-70/297
Sequence Identity: 28% (20 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEKILIKILRPNKIEK------------------VQREISILTKVN
| .|  || | |. | |. ..... ||  |||.  .|| .                  ..|||.|. ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN
Kinase 28298.AA Ciliate-E2a 99-177 29 7.4e-10 25.23 In-house 119-207 (275) Show / Hide 
Range on Protein: 99-177
Range on HMM: 119-207/275
Sequence Identity: 29% (26 aa)

HKIGVIHRDIKSANIIIN---HEK---RVLKVIDWGLSDIY--FPYSFNFCKIGTVNYKAPELILTDS--YHINITPAVDIWASGVIIF
|. ...|||.|  ||...    ..     .|.||.||.. .    . . | | ||  | |||..       | . .  .|.|  |||..
HQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFY
Kinase 28298.AA STE 99-202 21 1e-09 30.57 In-house 169-284 (359) Show / Hide 
Range on Protein: 99-202
Range on HMM: 169-284/359
Sequence Identity: 21% (27 aa)

HKIGVIHRDIKSANIIINHEKRVLKVIDWGLSDIYFP--------------YSFNFCK---IGTVNYKAPELILTDSYH--INITPAVDIWASGVIIFQM
|. ..||||||.||| .       | .| |.. .  .              ..        .||  . ||| |. .. .     .  .|||  |  |  |
HSHHIIHRDIKPANILL------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM

MINSVPLIKGHNSYTALLDIIKI
    .|. ..|. .  .. ....
ATGKPPWHDMHPMRAMFMIPFNY
Kinase 28298.AA CAMK1 258-283 34 1.9e-09 23.55 In-house 251-276 (276) Show / Hide 
Range on Protein: 258-283
Range on HMM: 251-276/276
Sequence Identity: 34% (9 aa)

DLIDKMLKILPNERISAKEALDHPYF
|.| .||.  |..|......|.|| .
DFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 28298.AA CAMK 258-283 42 3.2e-09 25.13 In-house 400-425 (425) Show / Hide 
Range on Protein: 258-283
Range on HMM: 400-425/425
Sequence Identity: 42% (11 aa)

DLIDKMLKILPNERISAKEALDHPYF
||| |||.  |..|......|.|| .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 28298.AA STE 20-86 18 4.3e-09 28.37 In-house 1-102 (359) Show / Hide 
Range on Protein: 20-86
Range on HMM: 1-102/359
Sequence Identity: 18% (19 aa)

YLVGSKLGSGKFSDVYLGYNKS-----NNYEK---------ILIKILR--------------------PNKIEKVQREISILTKVNS-IENVPKFYGITV
.   .|.|.| |  ||...|.       . |.         . ||...                    .........||.|. | |.  .|. |.||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DK
..
KE
Kinase 28298.AA Ciliate-E2 20-80 20 1.9e-08 25.12 In-house 1-98 (365) Show / Hide 
Range on Protein: 20-80
Range on HMM: 1-98/365
Sequence Identity: 20% (20 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEK----------------------ILIKILRPNKIEKVQREISILTKVN----SIEN------------VPKFY
| .  |.|.| |..||.. ........                      . .||...|.|| . .||.|. ..|     | |            . |.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY
Kinase 28298.AA Pkinase 248-283 27 4.4e-08 29.65 Pfam 259-293 (293) Show / Hide 
Range on Protein: 248-283
Range on HMM: 259-293/293
Sequence Identity: 27% (10 aa)

NVKYADPLGLDLIDKMLKILPNERISAKEALDHPYF
. ..... ..|.|...|.  |..|..|...| ||.|
F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 28298.AA Pkinase 20-72 26 1.2e-07 28.08 Pfam 1-59 (293) Show / Hide 
Range on Protein: 20-72
Range on HMM: 1-59/293
Sequence Identity: 26% (16 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEKILIKILRPNKIEKVQR-------EISILTKVNS
| .|.|.||| |. ||....|...  .  .||..  .... ..       ||.|. ..|.
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNH
Kinase 28298.AA TyrKc 20-227 16 2.2e-07 -103.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-227
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEKILIKILRPNKIEKVQREISILTKV-NSIENVPKFYGITVDK---------------------------YYQ--
   | |||.| |  ||.|  |    ..  .| |.....|   ||..|..|.  . .|. ..||. ...                           ...  
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

VPSLTIYQA-----------HKIGVIHRDIKSANIIINHEKRVLKVIDWGLSDIYFPY--------SFNF----CKI--GTVNYKAPELILTDSYHINIT
..  .  .            |. ..||||.   |. ..... . |. | |||     .                ..     .   ||| | .  .    |
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF----T

PAVDIWASGVIIF-----------Q-----MMINSVPLIKGHNSYTALLDI--------IKIFGYKDVMRLSSWSGIPLN----PQIYKEI
.. |.|. || ..                 |    |     .  .    .              |. .| .. |   | .     .|....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IM-KQCWHEDPEDRPTFSEIHECF
Kinase 28298.AA Ciliate-E2-Unclassified 20-61 23 3e-06 17.9 In-house 1-41 (352) Show / Hide 
Range on Protein: 20-61
Range on HMM: 1-41/352
Sequence Identity: 23% (10 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYEKILIKILRPNKIEKVQ
| .. ..|.| |..||. ..|... ..  .|..  ..| |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQK
Kinase 28298.AA CAMKL 258-283 38 3e-06 15.92 In-house 272-297 (297) Show / Hide 
Range on Protein: 258-283
Range on HMM: 272-297/297
Sequence Identity: 38% (10 aa)

DLIDKMLKILPNERISAKEALDHPYF
||| |||.  |..|..... . || .
DLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 28298.AA STE 258-283 39 7e-06 16.86 In-house 332-359 (359) Show / Hide 
Range on Protein: 258-283
Range on HMM: 332-359/359
Sequence Identity: 39% (11 aa)

DLIDKMLKILPNERISAKEALD--HPYF
| |.| |.. ||.| .|.. |   || .
DFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 28298.AA CAMK1 99-175 30 1.2e-05 12.35 In-house 125-205 (276) Show / Hide 
Range on Protein: 99-175
Range on HMM: 125-205/276
Sequence Identity: 30% (26 aa)

HKIGVIHRDIKSANIIINHE--KRVLK--VIDWGLSDIYFPYS-FNFCKIGTVNYKAPELILT---DSYHINITPAVDIWASGVI
|. |. |||.|  |.    .     .|  ..| ||| |. . . . .   ||  | ||| .     . |      |.|.|  |||
HSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY----DKACDMWSIGVI
Kinase 28298.AA CDK 99-130 38 1.3e-05 13.72 In-house 125-160 (284) Show / Hide 
Range on Protein: 99-130
Range on HMM: 125-160/284
Sequence Identity: 38% (14 aa)

HKIGVIHRDIKSANIIINHEKR----VLKVIDWGLS
|. ...|||.| .|| ||.       .||. | ||.
HSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLA
Kinase 28298.AA Ciliate-E2a 20-67 32 0.00055 7.65 In-house 1-53 (275) Show / Hide 
Range on Protein: 20-67
Range on HMM: 1-53/275
Sequence Identity: 32% (17 aa)

YLVGSKLGSGKFSDVYLGYNKSNNYE---KILIKILRPNK--IEKVQREISIL
| .  |.|.|.|  |||   | .. .   |..|| .. .|   |....||.|.
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIM