Gene 6129 (Tetrahymena)
6129
Sequence
Protein domains of 6129.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 6129.AA | CDC2 | 17-306 | 51 | 8.70000000001e-202 | 626.59 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-301/301 Sequence Identity: 51% (160 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGD-GFPSSSMREISTLKKMK-HENIVILKDVQFQFDENSLLMVFECLECDLKQYLENEFP-- .|||...||||||.|.||.|.||...||.|||.|| .. . |.||...||||.||..| |.||| |.||..| |.| ||||.|..|||.|.....| YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN --IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYT--KEIATLWYRAPEVMLGDEHYSITIDIWAVG ..|...|..|.||||||..|||..||||||||||||...|.| .||.|||||..|..|...|| .|. ||||||||..||...||...|.|..| KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN----IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIG CIFIEL---ITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPS-------NFNDPEALDLLSNLLVLDPSRRIFSK |||.|. .||.|.||..|.|||||.||.|.|||||||.||...||||...||....|...|..|. ..|||..|||...|..||..||..| CIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAK EALKHPYF |||.|||| EALQHPYF |
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Kinase | 6129.AA | CDK | 17-306 | 43 | 1e-159 | 514.82 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-284/284 Sequence Identity: 43% (138 aa) FQKIKMLGEGTYGHVTKCQDKQTK-----EVVAVKKIKLEIF----QGDGFPSSSMREISTLKKMKHENIVILKDVQFQFD---------ENSLLMVFEC ..|.. .||||||.| |..||||. ..|| |||..| ..|||... ||||.||.. |.||| |.|| . . ||.| |||| YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY LECDLKQYLENEFPIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNT-MSVKISDFGLAKTFTT------PLDKYTKEIATLWYRAPEV .. |||.|.. || .|.|.|.|..|||. ||||||||||||.. . ... ...|| |||||. | |. .||.|. ||||||||. MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL MLGDEHYS--ITIDIWAVGCIFIELIT---KRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNL ||..||| .||.|.|||||.|..| ..| |. .| ||||| ||.|.|||.|.. ||..||||| |||... LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLLNKM LVLDPSRRIFSKEALKHPYF |..||..|| ...||.|||| LCYDPKKRISAEQALQHPYF |
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Kinase | 6129.AA | CMGC | 17-306 | 27 | 3e-132 | 437.26 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-513/513 Sequence Identity: 27% (139 aa) FQKIKMLGEGTYGHVTKCQD--------------KQTKEVVAVKKIKLEIFQ--------GDGFPSSSMREISTLKKMK-----------------HENI ...|| .|||||| | ||.| ..|.|.||.||||.. .. .||||... |||. ||... |.|| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI VILKDVQFQFD---------------ENSLLMVFECLECDLKQYLENEF---------PIQPIK------------IKQIM------KQILQGVD--YCH | |.|. . .|.| .|||....||.||..| | . . || .| .|||.|.. ||| VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH QMQ--IMHRDLKPQNILVSTKANN----------------TMSVKISDFGLAKTFTTPLDK---------------------YTKEIATLWYRAPEVMLG .. |.||||||.|||.. . . . .|| |||||. . .. |. || ...|.||||||..|| SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG DEHYS---------ITIDIWAVGCIFIELITK--------RPPFH-----------AQSQIDQLFQIFQIFGTPN---------------EQTYPGISKL ..||. .||.|.||||| |..|. .| |. .| |||||.||...|||. |...|...|| WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKL PDY----------------NEK----------FPKFQAQGIQKLLPSNFN---------------------------------DPEALDLLSNLLVLDPS |.| .|. ||... . ...| | . | ||.|.|||...|..||. PWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPD RRIFSKEALKHPYF .|| ..||.|||| KRITAEQALQHPYF |
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Kinase | 6129.AA | CDK5 | 17-306 | 42 | 1.3e-115 | 366.92 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-287/287 Sequence Identity: 42% (126 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN-EFPIQP ..|. .|||||| | | ..|.|.|.|| |...|. | ||. .|||. || .||.||| | || |. | .||| . ||| |... . ... YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDS-EDEGVPSTAIREICLLKELKHKNIVRLHDVIHS--EKKLTLVFEFCDQDLKKYMDSCNGEMDM IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI || .| | |.|. .||. ...|||||||| |.... . | ||||| | | |. |. |||||.| |..| ||| ||.| .|||| |.. HIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGE----LKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMA -TKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYN---EKFPKFQAQG-IQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF . || | .. |||..||.| |||.| . |.|.|||||. ...|...|. |.. |. | . .|||...|...| || |.||.|||| NAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPK--LDEKGMDLLQKMLQCNPNQRISAKAALHHPYF |
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Kinase | 6129.AA | CDK7 | 17-306 | 36 | 1.6e-112 | 301.06 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-288/288 Sequence Identity: 36% (110 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIK----LEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLE-NEF ..||| .|||... | | .|.|| ..||.|||| . .. || . .||| |. |.|.|.. | |. . . .. .||. .. || . .. YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAK-DGINRTAIREIKILQEMQHDNVIGLIDIFMHKS--NIQLVFDFMDWDLEVVIKDKSI PIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIF | || .|...|||. |||. | |||||| | |.. .|| |||||. . | || . | |||||| | || .|.|.||||| ILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQ----LKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIF IELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQA---QGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF ||. | . .| |||| |||. |||.|.. |......||. || .| . ... .| .|||.. .. ..|..|. ..||.||| AELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYI-KFKDFPGYSRTPLRHIFTAASDD--LLDLMCGMWTMNPCKRWTCTQCLKMPYF |
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Kinase | 6129.AA | S_TKc | 17-306 | 29 | 9.1e-98 | 332.03 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-231/231 Sequence Identity: 29% (91 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLEC---DLKQYLENEFP- ..... .|.|..| | ||..| |...||.|.|| . .|||. ||| .|.||| |.|| ..| ||.|... ||..|... . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRH -----IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSI-TIDIWA . . .. .|.||.....|||...|.||||||.|||... .||.|||||. . | . |.||.||||. .|. .|.|. GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWS VGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALK---- .|||..|... .|||. |....|.. | .|||.|.....|. ||..|. |||. CGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD ---HPYF ||.| IKCHPWF |
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Kinase | 6129.AA | PITSLRE | 17-306 | 42 | 2.8e-94 | 319.51 | In-house | 1-295 (295) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-295/295 Sequence Identity: 42% (126 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLE-IFQGDGFPSSSMREIS-TLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLENEF--- ||.. .||||| | . .||.| |.|| |..|.| .||| |.|||. |. ..|.||| .| . . .. ||.| .| ||| .|| FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN -PIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCI | .| || | | | ||.. | ||||||| |.| | | . || ||||| . |. .||. . ||||||||. || . || .|.| |||| QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGI----LKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCI FIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNE-K-FPKFQAQGIQKLLP--SNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF | |.||..| | .| |||. .||. .|||.|. ||...|| . . ||. |. | .| ..||| .| ..| .|| .|||||.| FAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNNFPHYPYNNLRKRFPAENHISD-TGFDLLNQMLTYNPKNRITASDALKHPWF |
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Kinase | 6129.AA | PCTAIRE | 17-306 | 40 | 3e-85 | 289.54 | In-house | 1-291 (291) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-291/291 Sequence Identity: 40% (120 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLE-NEFPIQP . |. |||||| | ||. | | .|| | |.|| .. | | ||.| || .|| ||| | |. .. . .| .||| .. |||||.. . .. YIKLDKLGEGTYATVYKCRSKLTDNLVALKEIRLE-HE-EGAPCTAIREVSLLKDLKHANIVTLHDIIHT--HHQLTLVFEYMDMDLKQYMDDCGNIMNM IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI . .| .. |.| | .|||. .|.|||||||| |. | | |||||. | | .|. ||||| |.|..| || ||.| ||||| |. HNVKLFLFQLLRGLAYCHRRKILHRDLKPQNLLI----NERGELKLADFGLARAKSVPTKTYSHEVVTLWYRPPDVLMGSTDYSTQIDMWGVGCIFYEMC TKRPPFHAQS------QIDQLFQIFQIFGTPNEQTYPGISKLPDY-NEKFPKFQAQGIQKLLPSNFN--DPEALDLLSNLLVLDPSRRIFSKEALKHPYF | || | ||| ||.| ||| |.| ||.. .... .. ||....| . | . . |||..|| . . |. .|.||||| TGRPLFPGSTDSHYPGVKDQLHMIFRILGTPDEKTWPGVKSNEEFRTYNFPRYREQPLINHAP-RLDKILKQCQDLLTMLLQYESKNRVSAEKAMKHPYF |
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Kinase | 6129.AA | RCK | 17-306 | 38 | 3.9e-85 | 270.06 | In-house | 1-298 (298) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-298/298 Sequence Identity: 38% (118 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPS----SSMREISTLKKMK-HENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN-- | || ||.|||| |.| |.| |.|.|| || | |.| . ||| |.|.. |.||. ||.| .. |. .| |||... .| |.... YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK------QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFK --EFPIQPIK--IKQIMKQILQGVDYCHQMQIMHRDLKPQNILVST-----KANNTMSVKISDFGLAKTFTTPLDK--YTKEIATLWYRAPEVMLGDEHY . ... .. || ||.||||| ...| ..|||||| ||... .. .|| ||||.. . .| || . | ||||||. | . .| ERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIR---SKPPYTDYVSTRWYRAPECLLRCTYY SITIDIWAVGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYP-GISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFS . .||||||||..|| ..|| | .| |||.|.| .. |||| ...| |. . | .||. .......|.|. .....|. .| ||. || NSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPN--CSQDCIELMEKMLQWDPQKRITA KEALKHPYF ..||.|||| QQALQHPYF |
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Kinase | 6129.AA | Pkinase | 17-306 | 32 | 8e-85 | 292.91 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-293/293 Sequence Identity: 32% (100 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMR--EISTLKKMKHENIVILKDVQFQFDENSLLMVFECLEC-----DLKQYLE- ..... .|.|..| | ||..| | ..||||.||.. . .... . | ||. .|...|.||| |.|. .... ||.|..|. ||. |.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST -NEFPI--QPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTF-TTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDI .. .. .. .| .|.|||.|..|||.| |.||||||.|||.. . .. .|||.|||||| | . . .| |.||.|||| .|...|. .|. WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM WAVGCIFIELITKRPPFHAQ----SQIDQLFQIFQIFGTPNEQTYP-GISKLPDYNEKFPKFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKE |..|||..|....|||| . . .||.. |..| |.|.. .| .|. ... .. . . ... | . .|..|.....| .||..|. .. WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---FHWTF-HNWS-EECKDFIKWCLCKDPKKRPTAEQ ALKHPYF .|.||.| ILQHPWF |
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Kinase | 6129.AA | CRK7 | 17-306 | 34 | 1.7e-83 | 283.66 | In-house | 1-343 (343) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-343/343 Sequence Identity: 34% (120 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIF--QGDGFPSSSMREISTLKKMKHENIVILKDVQFQ--------FDENSLLMVFECLECDLKQY ...|. |||||| | | ..|.|.| || ||.... . .||| . ||| |. ..|.||| ||.. . | |||| || YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL LENE-FP-IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPL--DKYTKEIATLWYRAPEVMLGDEHY---- ||. . . . .| .|||.| |.||||. ..|||.| |||. || ||| ||||| . .|| . |||||.|| ||.|.| LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILM----NNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQH ----------------------------------SITIDIWAVGCIFIELITKRPPFHAQSQIDQLFQIFQIFGTPNEQTYPGISKLPDYNEKFPKFQAQ ||.| .|||..|| ||.| | .. ..|| |..| |.|| . | . ||| .| || . ILKELIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNNWPEVMKLPWWNTMKPK---R GIQKLLPSNFN--------DPEALDLLSNLLVLDPSRRIFSKEALKHPYF . .| .| ..|.|||| ..|.|||. |. .|.| |..| QYNRRLREEFYHHKKPVFMPKECLDLLDKMLCLDPKKRFTAEECLQHDWF |
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Kinase | 6129.AA | PFTAIRE | 17-306 | 38 | 2.3e-83 | 283.25 | In-house | 1-287 (287) | Show / Hide |
Range on Protein: 17-306 Range on HMM: 1-287/287 Sequence Identity: 38% (114 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKMKHENIVILKDVQFQFDENSLLMVFECLECDLKQYLEN-EFPIQP ..|.. ||||.| | | . .. .|| | |.|. | | | || | || .|| |||.| |. . | .||| .. ||.||.. ..| YEKLEKLGEGSYATVYKGISCINQQFVALKEIRLQ--QEEGTPFTAIREASLLKNLKHANIVCLHDIIHT--KETLTFVFEYVHTDLCQYMDKHPGGMHP IKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTPLDKYTKEIATLWYRAPEVMLGDEHYSITIDIWAVGCIFIELI .. . | | | |||| ...|||||||| |.| . | ||||| | | .|. ||||| | |.|| || .|.| |||||.|.. NNVRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGE----LKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMM TKRPPFHAQ-SQIDQLFQIFQIFGTPNEQTYPGISKLPDYN-EKFP--KFQAQGIQKLLPSNFNDPEALDLLSNLLVLDPSRRIFSKEALKHPYF . .| | ||| .||.. |||.|.|.||...|| |. ..|. .. . .. .|. . |.| ||....| . | |. .||..|||| WGQPAFPGMKDITDQLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRIYYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF |
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Kinase | 6129.AA | Pkinase_Tyr | 17-169 | 32 | 3.7e-18 | 62.14 | Pfam | 1-160 (270) | Show / Hide |
Range on Protein: 17-169 Range on HMM: 1-160/270 Sequence Identity: 32% (56 aa) FQKIKMLGEGTYGHVTKCQDK----QTKEVVAVKKIKLEIFQGDGFPSSS------MREISTLKKM-KHENIVILKDVQF-QFDENSLLMVFECLEC-DL ...|.|||| .|.| |. | .|| ||||..| .| .. |||....|.. .|.||| | | | . |....|.| .. || ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL KQYLEN----EFPIQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKT . || . . |. . . |. || .| .| ..... |||| |.||. .. |||.|||||.. LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARD |
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Kinase | 6129.AA | TyrKc | 17-286 | 25 | 4.5e-13 | -11.32 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 17-286 Range on HMM: 1-280/280 Sequence Identity: 25% (76 aa) FQKIKMLGEGTYGHVTKCQDKQTKEVVAVKKIKLEIFQGDGFPSSSMREISTLKKM--KHENIVILKDVQFQFDE-----NSLLMVFE-CLECDLKQYLE ...|.|||| .| | |.. | . ||||..| . |||.. ..| .|.||| | | | . |..|.| . |||.|| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR NEFP-IQPIKIKQIMKQILQGVDYCHQMQIMHRDLKPQNILVSTKANNTMSVKISDFGLAKTFTTP------LDKYTK-----EI--ATLWYRAPEVMLG . | ... . ... || .| .| |.... |||| |.||. . ||||||||.. . | |.| . . |||.. KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- DEH-YSITIDIWAVGCIFIELITK-RPPFHA-----QSQIDQLFQIFQIFGTPNEQT-YPGISKLPDYNEKFPKFQAQGIQKLLPSNFND-PEALDLLSN ... ... |.|. | |. | .| | .. . .. | . | . || .| . |. | ... . .| | .. . NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS----F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC L . F |