Gene 7563 (Tetrahymena)

7563

Species: Tetrahymena
Alias: 7563, PreTt07563, TTHERM_00677990, 337, 102.m00083, 3730.m00010
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
7563.AA Protein None 940 None Fasta, JSON
7563.kin_dom Protein Kinase Domain None 287 None Fasta, JSON
7563.NA RNA None 2823 None Fasta, JSON

Protein domain

Protein domains of 7563.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7563.AA CK1-Unclassified 21-300 42 1.3e-176 525.76 In-house 1-244 (244) Show / Hide 
Range on Protein: 21-300
Range on HMM: 1-244/244
Sequence Identity: 42% (123 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMELKNEF-------GYARMITYGKD--EDYNYVVMTNLGKNLDSILKKCGQ
.|..||.||||||.|.||||....|..|.|.||.|.. ...|..|.|.|..|.|..       |...|...|..  .|||..||..||..|......|..
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNR

RFSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQAKNLEIIFSFVCAKIPSQQNQKNKLNKIDKYQQNYTFTARIILKISEDCVKIVK
.||| |...||.|||.|.|.|||.|.|||||||.||..|.                                    ...|...   | . .|  ....  
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGK------------------------------------LGKNHHQVYIIDFGLSKRYIDM--

KPTLCWDSEGNHIPVVEKKGMIGTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLC
      |..|.|||  |.|...|||||||||||.|.|||||||||.|||||.||..|.||||.|.|..|.||||||..|||..|.||||
------DKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 7563.AA CK1 21-326 38 7.50000000001e-156 524.05 In-house 1-271 (271) Show / Hide 
Range on Protein: 21-326
Range on HMM: 1-271/271
Sequence Identity: 38% (122 aa)

FRLEEKLGQGSFGMIFKCINLENQEV---YAMKMEKRNQRHSSMLVREIKVMMELKN------EFGYARMITYGKD--EDYNYVVMTNLGKNLDSILKKC
.|...|.||||||.|...||. ....   .|.|.||....|. .|..|.|....|..      . |...|...|..  .|||..||..||..|.. ...|
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHP-QLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFC

GQRFSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQAKNLEIIFSFVCAKIPSQQNQKNKLNKIDKYQQNYTFTARIILKISEDCVKI
...||| |...||.|||.|.|..||.|.|||||||.||..|                                     |... .    |   ..  ..  
NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR------------------------------------YGKHCHQVYIIDFGLAKRYR--

VKKPTLCWDSEGNHIPVVEKKGMIGTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEG-CPNELV
       .|....|||  |.|...|||||||||.|.|.|||||||.|.|||||.||.||.||||...|.||..|||||...||..|.||||.| .|||..
-------DDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFA

QYLRMVKKLEFTEQPNYA
.||. ...|.| |.|.|.
MYLNYCRQLHFEEKPDYM
Kinase 7563.AA CK1 21-150 31 7.9e-54 185.14 In-house 1-166 (339) Show / Hide 
Range on Protein: 21-150
Range on HMM: 1-166/339
Sequence Identity: 31% (53 aa)

FRLEEKLGQGSFG-MIFKC-----INLENQ-----EVYAMKMEKRNQRHS-SMLVREIKVMMELKNE-------------------FGYARMITYGKDED
.....|.|.|.|| .|.|.     ....|.     | ||||.|....... ..| .|......|..                     .. .|. |.. ||
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNYVVMTNLGKNLDSILK---KCGQRFSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIG
  |||.||| ||.||....|    |...||. | ..||.||. .||..|... |||||||.||..|
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMG
Kinase 7563.AA CK1 218-328 37 2.9e-50 173.32 In-house 213-339 (339) Show / Hide 
Range on Protein: 218-328
Range on HMM: 213-339/339
Sequence Identity: 37% (48 aa)

DSEGNHIPVVE---KKGMIG-TARYASINAHQGLEQSRRDDLEALGYVLLYFIRGK--LPWQQIYAETK-------DEKYEKIKNMKMNYPLEQLCEG--
|... |.|  |   |||..| ||||.|||.|.| ||.|||||....|.|.....|.  |||| . .|.|       ..|||.|...||..|.. ||..  
DKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKK

---CPNELVQYLRMVKKLEFTEQPNYAAL
   || |. ... ....|.. . |.|...
DHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 7563.AA CK1-G 223-328 50 8.7e-49 163.44 In-house 159-266 (266) Show / Hide 
Range on Protein: 223-328
Range on HMM: 159-266/266
Sequence Identity: 50% (54 aa)

HIPVVEKKGMIGTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEG--CPNELVQYLRMVKKLEFT
|||  |.| . ||||| ||| | | |||||||.|||| . .|| ||.||||   |..  |.|.|| . | . . | ||..   | .. .||| | .|.| 
HIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFF

EQPNYAAL
|.| |  |
ECPDYDYL
Kinase 7563.AA CK1-D 223-328 56 3.3e-48 166.47 In-house 156-261 (261) Show / Hide 
Range on Protein: 223-328
Range on HMM: 156-261/261
Sequence Identity: 56% (60 aa)

HIPVVEKKGMIGTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEGCPNELVQYLRMVKKLEFTEQ
|||  |.| . ||||||||| |||.|||||||||.|||||.|| || |||| . | || .|||.| . ||. ....||.| |.| .||.  ...|.| ..
HIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDK

PNYAAL
|.|. |
PDYCYL
Kinase 7563.AA CK1-A 223-328 59 6.8e-47 162.1 In-house 156-261 (261) Show / Hide 
Range on Protein: 223-328
Range on HMM: 156-261/261
Sequence Identity: 59% (63 aa)

HIPVVEKKGMIGTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEGCPNELVQYLRMVKKLEFTEQ
|||  | | ..|||||||||||.|.|||||||.|..|||..|| ||||||| . | ||  |||||   ||  |.|||| | | |.  |.  ...| | ||
HIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQ

PNYAAL
|.|  |
PDYMYL
Kinase 7563.AA Worm6 21-150 34 1.2e-36 128.03 In-house 1-138 (279) Show / Hide 
Range on Protein: 21-150
Range on HMM: 1-138/279
Sequence Identity: 34% (48 aa)

FRLEEKLGQGSFGMIFKCINLENQE--VYAMKMEKR-NQRHSSMLVREIKVMMELKNEF--GYARMITYG-KDED-YNYVVMTNLGKNLDSILKKC-GQR
. ...|.|.|.|| ..|. . .. .   .||| ||.  .....|| .|. |....|..   .  ... .| .|.. .||.||| .||||  . | . ...
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIG
||..| . ||.|.. ..|.|||.  ||||.|| || ||
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIG
Kinase 7563.AA CK1-A 21-157 43 5.6e-36 124.57 In-house 1-136 (261) Show / Hide 
Range on Protein: 21-157
Range on HMM: 1-136/261
Sequence Identity: 43% (60 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMELKNEFGYARMITYGKDEDYNYVVMTNLGKNLDSILKKCGQRFSLATCMN
.||  |.| |||| |.  ||..| |  |.|||... ||   |. | ||   |.   |  .|  ||.. ||| .||  ||  |. .   |  ||.. | . 
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARH-PQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLM

IAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQ
.|.|||.|.| .|..| |||||||.||..| .|  |.
LADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNK
Kinase 7563.AA TTBKL 21-150 30 4e-32 105.8 In-house 1-136 (288) Show / Hide 
Range on Protein: 21-150
Range on HMM: 1-136/288
Sequence Identity: 30% (41 aa)

FRLEEKLGQGSFGMIFKCINLEN-QEVYAMKMEKRN-QRHSSMLVREIKVMMELK--NEFGYARMITYGKDEDYNYVVMTNLGKNLDSILKKCGQR--FS
.. ....|.| || ... ..... ....|||.||.   . .| .  |..|.|.|   .   ..... .|| .|||..||| .|.||. . |.  ..  ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIG
  | . |. | .  |  .| .  ||||.|| |...|
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWG
Kinase 7563.AA CK1-D 21-150 37 7e-31 106.1 In-house 1-129 (261) Show / Hide 
Range on Protein: 21-150
Range on HMM: 1-129/261
Sequence Identity: 37% (49 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMELKNEFGYARMITYGKDEDYNYVVMTNLGKNLDSILKKCGQRFSLATCMN
.|.  |.| |||| |.   |... |  |.|.|    .|  . . | |.   ..   |  ..  .|.. ||| .||  ||  |. .   |. .||| | . 
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHI-ESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLM

IAEQMITRLEVLHNHNLIHRDIKPENFVIG
.|.|||.|.| .| .| |||||||.||..|
LADQMICRIEYIHCRNFIHRDIKPDNFLMG
Kinase 7563.AA CK1-G 21-164 35 9.2e-27 87.67 In-house 1-143 (266) Show / Hide 
Range on Protein: 21-164
Range on HMM: 1-143/266
Sequence Identity: 35% (51 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMELKNEF-GYARMITYGKDEDYNYVVMTNLGKNLDSILKKCGQRFSLATCM
.|   | | |.|| .|   |. | |  | |.| .  |    |  | .    |     |  .   .|    ||  ||  ||  |      |. .||. | .
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSR-APQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVC

NIAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQAKNLEII
 .| |||.|.| .| |.|| ||.||.|| ||   | ...... ||
MVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGR-PSNKDQHVIHII
Kinase 7563.AA Worm6 234-328 25 7.6e-23 78.96 In-house 183-279 (279) Show / Hide 
Range on Protein: 234-328
Range on HMM: 183-279/279
Sequence Identity: 25% (25 aa)

GTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDE-KYEKIKNMKMNYPLEQLCEGCPN-ELVQYLRMVKKLEFTEQPNYAAL
|| |||....|.| ||.|.||.|   |... .|.|.|||... ..  .|  .... . .  .  ... ..||  |..  . .. .. . . |.|. .
GTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 7563.AA TTBK 234-328 40 1.3e-22 76.75 In-house 169-257 (257) Show / Hide 
Range on Protein: 234-328
Range on HMM: 169-257/257
Sequence Identity: 40% (38 aa)

GTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEGCPNELVQYLRMVKKLEFTEQPNYAAL
||.||||||||.  |  |.|||  | |.|  |. | |||  |    ||   ... .||  | .  | . || |. |..  .| |.. ..|.|. .
GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKI----KDK--DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 7563.AA TTBK 21-150 33 4.3e-22 74.88 In-house 1-131 (257) Show / Hide 
Range on Protein: 21-150
Range on HMM: 1-131/257
Sequence Identity: 33% (44 aa)

FRLEEKLGQGSFGMIFKCINLENQ-EVYAMKMEKRNQRHSSMLVREIKVMMELKNEFGYARMITYGKDEDYNYVVMTNLGKNLDSI-LKKCGQRFSLATC
 .   | |.| || |.   .. |. |  |.|.|. .|     |  |. |.  |       | |. | ....||.||. .||||     |   . ||| | 
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPK-QVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTT

MNIAEQMITRLEVLHNHNLIHRDIKPENFVIG
. .  |..  .|  |.    |||||| || .|
LRLGVQILQSIESIHSVGFLHRDIKPSNFAMG
Kinase 7563.AA CMGC 21-146 16 4.3e-22 68.57 In-house 1-214 (513) Show / Hide 
Range on Protein: 21-146
Range on HMM: 1-214/513
Sequence Identity: 16% (36 aa)

FRLEEKLGQGSFGMIFKCIN--------------LENQEVYAMK---MEKRNQRHSS----------MLVREIKVMMELK-----------NEFGYARM-
.   .|.|.|..|. .||..               |..|..|.|    .. ....            .  |||| ...|.           ....  .  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IT------YGKDED---------------YNYVVMTNLGKNLDSILKKCG---------------------------QRFSLATCMNIAEQMITRLE--V
|       | |..|               . | |.  ....|  ..|..                            . |..  .  .. |... |.   
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHNHN--LIHRDIKPEN
.| |.   ||||.||||
CHSHWGNIIHRDLKPEN
Kinase 7563.AA TTBKL 234-332 29 7.9e-22 70.54 In-house 191-288 (288) Show / Hide 
Range on Protein: 234-332
Range on HMM: 191-288/288
Sequence Identity: 29% (31 aa)

GTARYASINAHQGLEQSRRDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEG------CPNELVQYLRMVKKLEFTEQPNYAA
|| ||.|.|.|...||.| ||| .. |.. ..  | |||. .  .      ..|  ||.|  .|.|. .      || |.    .... |.. ..|.|  
GTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEM

LKALF
. ..|
IYECF
Kinase 7563.AA Pkinase 21-152 26 3.8e-20 72.33 Pfam 1-144 (293) Show / Hide 
Range on Protein: 21-152
Range on HMM: 1-144/293
Sequence Identity: 26% (39 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVR-----EIKVMMELKNEFGYARMITYGKDEDYNYVVMTNLGK-----NLDSILK-KC
.....|.|.||||  .||..  .....|.|  |.  ..|.....     ||..| .|. ..   |.. .  |.|. |.||  ...      | .... . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI-VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

GQRF--SLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIGPD
. .|  |  .| ... |..  || .|... ||||.||||. |  .
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNN
Kinase 7563.AA S_TKc 21-320 15 9.2e-14 24.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-320
Range on HMM: 1-231/231
Sequence Identity: 15% (50 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMELKNEFGYARMITYGKDEDYNYVVMTNLGK---NLDSILKKCGQR-----
... .|.|.|.||  .||.. . ....|.|. |       .. |||.....  .     ... .  | |. |.||  ..    .| ...||.| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQAKNLEII-FSFVCAKIPSQQNQKNKLNKIDKYQQNYTFTARIILKISEDCVKIVK
|.  ..  .. |..  || .|.|. ||||.||||  .          .. |. | . .                                          
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL----------------------------------------

KPTLCWDSEGNHIPVVEKKGMIGTARYASINAHQGLEQSR-RDDLEALGYVLLYFIRGKLPWQQIYAETKDEKYEKIKNMKMNYPLEQLCEGCPNELVQ-
                  . ..||  | .         .. . |  ..| .|  .. |. |..     . .. ..||.      .. .. ..| .   . 
------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG----SPEAKDFIRKCLQKDPEK

----YLRM----VKKLEFT
     .      .|. .. 
RPTAEALQDEWDIKCHPWF
Kinase 7563.AA TyrKc 21-332 13 3e-06 -120.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-332
Range on HMM: 1-280/280
Sequence Identity: 13% (50 aa)

FRLEEKLGQGSFGMIFKCINLENQEVYAMKMEKRNQRHSSMLVREIKVMMEL--KNE-----FGYAR------MITYGKDEDYNYVVMTNLGK--NLDSI
 .|..||| | || ..|..    ..| | || | .     .. ||...|..|  ...     .|...      |      ..  . . . . .  .|.. 
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFM------YIEPLMIVMEYMPHGDLKDY

LKKCGQRFSLATCMNIAEQMITRLEVLHNHNLIHRDIKPENFVIGPDRSFNQAKNLEIIFSFVCAKIPSQQNQKNKLNKIDKYQQNYTFTARIILKISED
|.|.. ......  ... |     | || .|.||||.   |  .| ..                                                    
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------------------------------------------------

CVKIVKKPTLCWDSEGNHIPVVEKKGMIGTARYASIN-------AHQGLEQSRRDD---------LEAL-GY------------VLLY--FIRGKLPWQQ
                     . | .  | .|.                 ...  .         .|..  .            |...  | .|. |.  
---------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPG

IYA--ETKDEKYEKIKNMKMNYPLEQLCEG-----CPNELVQYLRMVKKLEFTEQPNYAALKALF
.     . .| .|..|. ..  . .  .       || |. |  ..  . .  . |. .... .|
MIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 7563.AA Pkinase_Tyr 21-75 27 3.4e-05 18.23 Pfam 1-64 (270) Show / Hide 
Range on Protein: 21-75
Range on HMM: 1-64/270
Sequence Identity: 27% (18 aa)

FRLEEKLGQGSFGMIFKCINL-----ENQEVYAMKMEKRNQRHS----SMLVREIKVMMEL-KNE
 .. .|||.|.||...|..       ....| | || | .  |.     .. ||.|.|..| ...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPV-AVKMLKEGAMHEQNCREDFMREAKIMKQLGHHP
Kinase 7563.AA Pkinase 234-302 14 0.022306 9.49 Pfam 173-245 (293) Show / Hide 
Range on Protein: 234-302
Range on HMM: 173-245/293
Sequence Identity: 14% (11 aa)

GTARYASINAHQ-GLEQSRRDDLEALGYVLLYFIRGKLPWQQI----YAETKDEKYEKIKNMKMNYPLEQLCEG
|| .|..   .. | . ... |  ..| .| ... |..|...        ........|.  .  .. ...|..
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSI