Gene 5508 (Tetrahymena)

5508

Species: Tetrahymena
Alias: TTHERM_00440530, PreTt05508, 3708.m00128, 5508, 49.m00280, 432
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
5508.AA Protein None 309 None Fasta, JSON
5508.kin_dom Protein Kinase Domain None 241 None Fasta, JSON
5508.NA RNA None 930 None Fasta, JSON

Protein domain

Protein domains of 5508.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5508.AA CK1-Unclassified 10-247 56 6.30000000001e-186 553.69 In-house 1-244 (244) Show / Hide 
Range on Protein: 10-247
Range on HMM: 1-244/244
Sequence Identity: 56% (138 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNN--RGLPHVYYTARE--GDFTYMVMDRLGSSLEDLFQKCGR
.....|.|.| ||.||...|...| ||||||||.|| .|||.|||.....| ..... .|  .|.|..|. ..|  ||. .|||| ||.||||||..|.|
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNC-DNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNR

KFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMG-RGRNAHIVYIVDFGLAKKLVT--RNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRDDL
||||||||||. ||..||...|.|  .|||||||||||| .|.|.|.|||.||||.|. ..  ..|.||||.||||.||||||||. .||||||.|||||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

EGMMYVLLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVF
| ..|||.||| |||||.... |.|||||.||||.||........
ESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 5508.AA CK1 10-273 57 1.9e-174 585.82 In-house 1-271 (271) Show / Hide 
Range on Protein: 10-273
Range on HMM: 1-271/271
Sequence Identity: 57% (157 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLE---VAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNN--RGLPHVYYTARE--GDFTYMVMDRLGSSLEDLFQK
.....|.|.| ||.|||| |. .| |   ||||||||.| .|||.|||..||.| .. .. .|   |.||.|. ..|  ||. .|||| || ||||||..
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGH-NC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNF

CGRKFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGR-GRNAHIVYIVDFGLAKKLVT-RNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRD
|.|||||||||||. ||..||...|.|. .||||||||||||| |...|.|||.||||||. .  ....||||.||||.||||||||. |||||||.|||
CNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRD

DLEGMMYVLLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFND-LPKEFVELFKYIRNLEFEEIPDYD
|.| ..|||.||| |||||.|.. ||||.||.|||||||.... . ... .|.||.....|.|.|.||| |||.
DMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 5508.AA CK1 10-275 37 1.4e-125 423.47 In-house 1-339 (339) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-339/339
Sequence Identity: 37% (127 aa)

FKLTKKLGSGGFG-QIYLG-----VNTKSN-----LEVAIKLEKNNSA--CPQLQYEAQFYKRLLKDAS-------------VLNNRGLPHVYYTAREGD
.|..||.|.|||| |||..     ...|.|      |.|.|.|...|.   |||..|.|.|| | . ..             ...... |..|. . |.|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--FTYMVMDRLGSSLEDLFQ---KCGRKFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGR------GRNAH--------IVYIVDFGLAK-KL
  . ||||..|| .||||..    |.||||.||.|||.|||.|.....|..  .|||||||||.|||      |.. |        .||..|||.|. | 
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

VTRNGS------------HIPYKE---NKNFTG-TARYASLTTHLGIEQGRRDDLEGMMYVLLYFLLGS--LPWMGVRSNTK-------KEKYDKIMEKK
....|.            |.|..|   .|.|.| ||||.|. .|||.||||||||. ..|.|...| |.  |||.......|       |.||..|.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

MTLCISEVFND-----LPKEFVELFKYIRNLEFEEIPDYDYI
| ...           .|.|| ...||||.|.....|||..|
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 5508.AA CK1-D 10-275 53 1.7e-123 416.61 In-house 1-261 (261) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-261/261
Sequence Identity: 53% (142 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRGLPHVYYTAREGDFTYMVMDRLGSSLEDLFQKCGRKFSL
... .|.||| ||.||.| | ..| |||||||   .  |||..|..||| .          |.|.. .  .|||.  |||| || ||||||  |.|||||
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGI------GIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSL

KTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRGRNAHIVYIVDFGLAKKLVTRN-GSHIPYKENKNFTGTARYASLTTHLGIEQGRRDDLEGMMYV
|||||.. ||. ||..||... .|||||||||||| |.  ..|||.||||||.    .   ||||.|||| ||||||||. ||.|||| |||||| . ||
KTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYV

LLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFNDLPKEFVELFKYIRNLEFEEIPDYDYI
|.|| .||||| |..  ||..||..|.||||   | .. . .|.||.. . | |||.|.. ||| |.
LMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 5508.AA CK1-A 10-275 53 2e-114 386.45 In-house 1-261 (261) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-261/261
Sequence Identity: 53% (142 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRGLPHVYYTAREGDFTYMVMDRLGSSLEDLFQKCGRKFSL
..| .|.||| || ||||.|...  |||||.|.|.   ||| |||. |. | .        |.||. .  .| |.  |||| || ||||||  | |.|..
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCV------GIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTM

KTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRGRNAHIVYIVDFGLAKKLV-TRNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRDDLEGMMYV
|||||.  ||. || ..| |  .|||||||||||| ||    ....|||||||    |   ||||.| || ||||||||.  |||||| ||||.| | ||
KTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYV

LLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFNDLPKEFVELFKYIRNLEFEEIPDYDYI
..|| .|.||| |.. .||| ||.|| ||||.  | ..    | ||  ...|.||| ||| ||| |.
MMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 5508.AA CK1-G 10-275 46 3.7e-112 378.91 In-house 1-266 (266) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-266/266
Sequence Identity: 46% (125 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRGLPHVYYTAREGDFTYMVMDRLGSSLEDLFQKCGRKFSL
..  || | | || ...| |   |. ||||.|   |  |||. | .||| |   .      |.|.|||   .| .  |||| || ||||||  |.||||.
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCP-----EGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSV

KTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGR--GRNAHIVYIVDFGLAKKLV-TRNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRDDLEGMM
|||.|. |||..|.. .||.. . ||.|||||| ||   ...|...|.|||.||. .  . . |||| | |  |||||| |  |||| || ||||.| . 
KTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALG

YVLLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFND--LPKEFVELFKYIRNLEFEEIPDYDYI
 . .||| ||||| | .  . ||.|.|| ..|  . |    .   .|..|    .|.|.|.|.| |||||.
HMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 5508.AA TTBKL 10-279 26 8.1e-63 210.91 In-house 1-288 (288) Show / Hide 
Range on Protein: 10-279
Range on HMM: 1-288/288
Sequence Identity: 26% (79 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRG----LPHVYYTAREGDFTYMVMDRLGSSLEDLFQKCGR
.. .|..|.|||||.|.....|.  ..|.. |      .. ..     . .  .  .... .     |....  ...|...|||  .| .| ||  .  .
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEE-----KNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPN

K--FSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRG----RNAHIVYIVDFGLAKKLVTRNGSH-----------IPYKE---NKNFTGTARY
|  ||  |.. |||| .. .. .|..  .|||.|| |. .|      .....||..|||.|.. .. .|.             . ..      | || ||
KKRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRY

ASLTTHLGIEQGRRDDLEGMMYVLLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFND------LPKEFVELFKYIRNLEFEEIPDYDYIKRTF
.|.  |.. |||| |||  .||.. ....| ||| ..      |. ..|...|. .    .| |      .|.|| . .|..|.|.. . |||..|   |
CSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNM------EDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 5508.AA Worm6 10-275 30 1.9e-62 213.78 In-house 1-279 (279) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-279/279
Sequence Identity: 30% (87 aa)

FKLTKKLGSGGFGQIYLGVNTKSNL--EVAIKLEK--NNSACPQLQYEAQFYKRLLKDASVLNNRGLPHVYYTAREGD--FTYMVMDRLGSSLEDLFQKC
.|.|||.|.|||| .|.  ... .   ..|.|.||   |.. ..|. |.      || .   ..|... .   .. .   | |.||  .| .|.|| . .
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECM----VLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNR

-GRKFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGR-----GRNAHIVYIVDFGLAK--KLVTRNGSHIPYK-ENKNFTGTARYASLTTHLGI
 .||||. | | |.||. |.|.  |.   .|||.|| ||  ||      .. |..|..|||...  |.  .... .. . ..  | || |||.|  | |.
PDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQ

EQGRRDDLEGMMYVLLYFLLGSLPWMGVRSNTKKE-KYDKIMEKKMTLCISEVFNDLPK-EFVELFKYIRNLEFEEIPDYDYI
||.|.||.|. .|... ...| |||....    .|  . ... ..     ...|.  || ||.. ..|| .. ... |||..|
EQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 5508.AA TTBK 10-275 37 9.9e-52 178.18 In-house 1-257 (257) Show / Hide 
Range on Protein: 10-275
Range on HMM: 1-257/257
Sequence Identity: 37% (102 aa)

FKLTKKLGSGGFGQIYLGVNTKSN-LEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRGLPHV--YYTA-REGDFTYMVMDRLGSSLEDLFQKCGR
 | .|| | |||| || . .   .  .||||.|. .     |. |    |.|          | .||  ...  |. .| ||||. .| .| ||  |  |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKL---------QGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPR

-KFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGR-GRNAHIVYIVDFGLAKKLVTRNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRDDLE
 .||| | | .|.|... |. |||   ||||||| || |||   .  ..|..||||| . ..  |   |  |   | ||.|||| . |.  | ||.||| 
GCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLW

GMMYVLLYFLLGSLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFNDLPKEFVELFKYIRNLEFEEIPDYDYI
 . |.|  |. | |||  .     | | |.. | |         ...|.||    . |. |..|. |||  |
SLFYMLVEFVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 5508.AA Pkinase 10-238 22 2.8e-31 111.66 Pfam 1-234 (293) Show / Hide 
Range on Protein: 10-238
Range on HMM: 1-234/293
Sequence Identity: 22% (59 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQY------EAQFYKRL-------LKDASVLNNRGLPHVYYTAREGDFTYMVMDRLGSSL
... .|.|||.||. |.... ... .||.|  |  .. .. ..      |.|  |||       |.|.                 .|  ||||. ..  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--------------KDHIYMVMEYCEGGL

EDLFQKC-------GRKF--SLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMG-RGRNAHIVYIVDFGLAKKLVTRNGSHIPYKENKNFTGTARYA
. ..  .       ...|  | ... ..  |... ....||. ..|||.||.|.|.  .| .. .| | ||||||..      . ..  .. |.|| .|.
Y-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYM

SLTTHL-GIEQGRRDDLEGMMYVLLYFLLGSLPWMGV----RSNTKKEKYDKIMEKK
.   .. | . |.. |  ..  .| ..|.| .|. |     . .........||...
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPP
Kinase 5508.AA Dual 86-279 27 3.1e-29 95.37 In-house 88-282 (282) Show / Hide 
Range on Protein: 86-279
Range on HMM: 88-282/282
Sequence Identity: 27% (56 aa)

YMVMDRLGSSLEDLFQKCGRK-FSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRGRNAHIVYIVDFGLAKKLVT-RNGSHIPYKENKNFTGTA
|.||   |.||..   | . . .|  .   ..|||.. ||  ||   |||.||| ||  | |     ||  ||....| .   |. | .   .  . |..
YWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCG

RYASLTTHLGIEQGRRDDLEGMMYVLLYFL-LGS-LPWMGVRSNTKKEKYDKIMEKK---MTLCISEVFNDLPKEFVELFKYIRNLEFEEIPDYDYIKRT
|||.    .  .||| ||||   | . . .  .. ..|       |.    .....|   |.   .. .   |.... |  |. .....  |||||.   
RYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWR------KECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNC

F
 
L
Kinase 5508.AA S_TKc 10-297 19 9.3e-16 54.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-297
Range on HMM: 1-231/231
Sequence Identity: 19% (60 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNRGLPHVYYTAREGDFTYMVMDRLGS---SLEDLFQKCGRK
... .|.|.|.||. |.....|.. .||||  |      ... | |  |.        .   . . |.. .. |. ||||. ..    .| |. .|.||.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----FSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRGRNAHIVYIVDFGLAKKLVTRNGSHIPYKENKNFTGTARYASLTTHLGIEQGRRDD
     |.  ..  .  |... ....||. ..|||.||.| |. .      . | |||||..|             . | ||  | .              
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL----------

LEGMMY---------VLLYFLLG-SLPWMGVRSNTKKEKYDKIMEKKMTLCISEVFNDLPKEFVELFKYIRNLEFEEIPDYDYIKRTFE-QVFNREGYEL
  |  .         ..|| .|    |.      . .. ..||.                                  .  | |.. ..    .| .   
--GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-E

DYQ-------YDWI
  |         |.
ALQDEWDIKCHPWF
Kinase 5508.AA TyrKc 10-254 18 7.2e-09 -79.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-254
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

FKLTKKLGSGGFGQIYLGVNTKSNLEVAIKLEKNNSACPQLQYEAQFYKRLLKDASVLNNR--GLPHV---YYTAREG-------DFTYMVMDRLGS-SL
 .| ||||.| ||..|.|. .   ..||.|  |...            . ... |... .     |..   |  ....       .  ..||      .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

EDLFQKCGRKFSLKTVLMIGIQMVERIQFIHSKDVLHRDIKPDNFLMGRGRNAHIVYIVDFGLAKKLVTR-----NGSHIPYKE--NKNFTGTARYASLT
 |  .|...|...|. | . .|  .  ...||| . |||.   | | |...   .| | ||||....        ... .  ||  ....    |  .  
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA--

THLGIEQGRRDDLEGMMY-------------VLLY--FLLGSLPWMG----------VRSNTKKEKYDKIMEK---------------KMTLCISE----
            .| ..|             |...  | .|  |. |          |. . |. .. ....                 |. |  |    
------------PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

--VFNDLPKEF
   |... ..|
RPTFSEIHECF
Kinase 5508.AA Pkinase_Tyr 10-60 30 2.2e-05 18.83 Pfam 1-60 (270) Show / Hide 
Range on Protein: 10-60
Range on HMM: 1-60/270
Sequence Identity: 30% (18 aa)

FKLTKKLGSGGFGQIYLGVNT----KSNLEVAIKLEKNNSACPQ-----LQYEAQFYKRL
 .. ||||.| ||..|.|. .    . ...||.|  |...  .|     .  ||.  | |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL
Kinase 5508.AA APH 131-160 22 0.000827 13.87 Pfam 172-202 (248) Show / Hide 
Range on Protein: 131-160
Range on HMM: 172-202/248
Sequence Identity: 22% (7 aa)

VLHRDIKPDNFLMG-RGRNAHIVYIVDFGLA
..|.| .|.|...  | .. ......|.. |
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDA
Kinase 5508.AA Dual 10-25 50 0.012509 4.51 In-house 1-16 (282) Show / Hide 
Range on Protein: 10-25
Range on HMM: 1-16/282
Sequence Identity: 50% (8 aa)

FKLTKKLGSGGFGQIY
 |  . ||||||. .|
WKVVNLLGSGGFRDVY