Gene 8052 (Tetrahymena)

8052

Species: Tetrahymena
Alias: 8052, 3716.m00082, TTHERM_00502130, PreTt08052, 394, 63.m00230
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CDPK

Sequence

Name Sequence Type Origin Length Description Download
8052.AA Protein None 497 None Fasta, JSON
8052.kin_dom Protein Kinase Domain None 257 None Fasta, JSON
8052.NA RNA None 1494 None Fasta, JSON

Protein domain

Protein domains of 8052.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8052.AA CDPK 51-307 59 3.3e-202 625.69 In-house 1-271 (271) Show / Hide 
Range on Protein: 51-307
Range on HMM: 1-271/271
Sequence Identity: 59% (161 aa)

TLMNVPLGKGSYGEVRKGVHK-KTGQQR-AVKIIDKSQCKPEEQ-KQLIEEFNILKQLDHPNIIKVYEVFQDNKFLYIVTE--LCTGGELFDRIIEYKHF
. .. .||||..|.|||..|| ||.|.| |.||| ||..| .|| .|...|..||||||||||||.||..||.|. |||.|  .||||||||.|||..||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

NEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDS----ILKLVDFGTSTVFDPS-----LKMSQKLGTPYYIAPEVLRHKYNEKCDVWSCG
.|||||..|.|||.|.|| |.|.||||||||||.|.|||..||    ..|..|.|||. ||..      ||||..|||||||||||..|||||||.||||
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG

VIMYILLCGYPPFNAARDEDIMKKVEKGVFTFPKDDWKDITIEAQQMICKMLTMDPQKRYSAEEALQDPWI
||.||||||||||..  |..||.||.||...| ...|..|. ||...|.|||..||.||.||..|||.||.
VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 8052.AA CAMK1 50-307 45 4.8e-154 451.24 In-house 1-276 (276) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-276/276
Sequence Identity: 45% (125 aa)

YTLMNVPLGKGSYGEVRKGVHKKT---GQQRAVKIID-KSQCKPEEQ---KQLIEEFNILK---QLDHPNIIKVYEVFQDNKFLYIVTELCTGGELFDRI
| .... .|.|. .||....||.|   |.| |.|.|| |.. | ...   ..|  | .|.|   ..||||||| ||........|.|.||.|||||||||
YEFGKE-IGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

IEYKHFNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDSILK--LVDFGTSTVFDPSL-KMSQKLGTPYYIAPEVLRHK----YNEKCDV
.| ....||.|...| ||| |..|.|.. ||||||||||||. .|  ||..|  . ||| |. ||.   .|..  |||.|.|||||  |    |  .||.
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WSCGVIMYILLCGYPPFNAAR-DEDIMKKVEKGVFTFPKDDWKDITIE-AQQMICKMLTMDPQKRYSAEEALQDPWI
||.||| ||||||||||.. . |. ...|. |. ..||.. | .|  . | . |..||. ||.|||..|..|..|||
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 8052.AA CAMK 56-307 31 2.4e-135 438.93 In-house 1-425 (425) Show / Hide 
Range on Protein: 56-307
Range on HMM: 1-425/425
Sequence Identity: 31% (132 aa)

PLGKGSYGEVRKGVHKKTG------------QQRAVKIIDKSQCK--------------------------PEEQKQLIEEFNILKQ-------LDHPNI
 ||.||.|.|....||.|.            |. |.|||||.. |                          |. .|..  | .|.|.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKVYEVFQD-------------------NKFLYIVT---ELCTGGEL----FDRIIEYKH---------------FNEKEAADVMYQILNAINYLHKNKI
|| |||..|                   .|..|.|.   |.|.||||    ||.|.| ..               |.|.||. .. ||. |..|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLLDSKNKDS--------------ILKLVDFGTSTVFDP------------------------SLKMSQKLGTPYYIA-PEVLRHK-----
|||||||||.|||..|.||               .|..||| ...|||                          ||.   |||.|.| ||||. |     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YNEKCDVWSCGVIMYILLCGYPPFNAA-------------RDEDIMKKVEKGVFTFPKDD------------WKDITIE--------AQQ
          |..|||.||||||.||.|||||||..               |.....|. || ..|| .             |.||. |        ...
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

MICKMLTMDPQKRYSAEEALQDPWI
.|.|||. ||.||...|..|..||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8052.AA Ciliate-E2a 50-307 43 3.1e-133 394.52 In-house 1-275 (275) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-275/275
Sequence Identity: 43% (120 aa)

YTLMNVPLGKGSYGEVRKGVHKKTGQQ-RAVKIIDKSQCKPEEQKQLIEEFNILKQLDHPNIIKVYEVFQDNKFLYIVTELCTGGELFDRIIEYKHFNEK
| . .. .|||..| |..  ||.||.| ...|.|.| . . ....... | ||..||||||||| |||..|.. .|.|.|.| ||||.|.|.. | |.|.
YKFIKK-IGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EAADVMYQIL-NAINYLHKNKIVHRDLKPENLLLD--SKNKD--SILKLVDFGTSTVFDPSLK--MSQKLGTPYYIA------PEVLRHK-YNEKCDV
  |..|.| |.|  ...|.|...|.||||||||.|..  |||..  | .|..|||..| .|.  |  | || |||.|.|      .||| || | .|||.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSCGVIMYILLCGYPPFNAARDEDIMKKVEKGVFTFPKDD-WKDITIEAQQMICKMLTMDPQKRYSAEEALQDPWI
||||||.||||||.|||..   ..| ....|  . |   . |.... |..... |||  ||.||..|..||..|| 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 8052.AA S_TKc 50-307 40 1.8e-111 377.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-231/231
Sequence Identity: 40% (111 aa)

YTLMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKPEEQKQLIEEFNILKQLDHPNIIKVYEVFQDNKFLYIVTELCTG--GELFDRIIEYKH---
|..... .|||..|.|.|..|||||.. |.|||.         .... | .|||. .||||.| |.|||| ..||.|.|.| |  |.|||.| ....   
YEILRK-IGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDSILKLVDFGTSTVFDPSLKMSQKLGTPYYIAPEVLRHKYNE-KCDVWSCGVIMY
   |.| .|. .||||..|..|.|...|.||||||||.|||.      .|. ||| ....      .   |||.|.|||||  .|.  |||.||||.|.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

ILLCGYPPFNAARDEDIMKKVEKGVFTFPKDDWKDITIEAQQMICKMLTMDPQKRYSAEEALQ-------DPWI
..|||||||    .. ..||.               . || ..|.|.|..||.||..| ||||       .||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8052.AA RAD53 52-307 35 1.2e-108 324.82 In-house 2-305 (305) Show / Hide 
Range on Protein: 52-307
Range on HMM: 2-305/305
Sequence Identity: 35% (111 aa)

LMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDK---S---QCKPEEQKQLIEEFNILKQLDHPNIIKVYEVFQD-NKFLYIVTELCTGGELFDRIIEYKH
.|.  ||.| .|.|.... |||.|. |.|||||   .      .   .|. .| .||| | ||.||. |..|..  | .|.| || ||||||..|.  | 
YMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNKR

----FNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDS---------------ILKLVDFGTSTVFDPSLKMSQKL-------GTPYYIA
    |.| .. .  ||...|..||| | |.|||||||| |.......                ..|. ||| |       | ...        ||| | |
CQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-------KFVGEGSFMKTMCGTPQYVA

PEVLRHK----------------YNEKCDVWSCGVIMYILLCGYPPFNAARD-----EDIMKKVEK-GVFTFPKDDWKDITIEAQQMICKMLTMDPQKRY
|||.. |                |. |.|.|| |.| ||.|||||||   ..      .. ... . | . ||. .|..|. ||. .| .||. || |||
PEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRY

SAEEALQDPWI
...|||. ||.
TIDEALNHPWM
Kinase 8052.AA CAMKL 50-307 35 2.7e-102 327.26 In-house 1-297 (297) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-297/297
Sequence Identity: 35% (106 aa)

YTLMNVPLGKGSYGEVRKGVH-KKTGQQRAVKIID--KSQCKPEEQKQ-----------LIEEFNILKQLD---HPNIIKVYEVFQDNKF------LYIV
|..    |||||.|.|. ..| . ||.. |.||||  | ...|  .|            .  | .|.|.|.   |||||| |||... ..      .|.|
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

TELCTGGE--LFDRIIEYKH----FNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDSILKLVDFGTSTVFDP-----SLKMSQKLGTPY
.|.| |||  |||.|.. .|    . |.||     ||. |.||.|...|||||.||||.|||....   .|..||| |. ..|       |..   |.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YIAPEVLRH--K-YN-EKCDVWSCGVIMYILLCGYPPFNAA-----RDEDIMKKVEKGVFTFPKD-DWKDITIEAQQMICKMLTMDPQKRYSAEEALQDP
| |||..    | |.  | |.||||||.| ..||| ||...      ...| .. .|   .  ..  |...  .....| |||. .| ||..... ...|
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WI
| 
WM
Kinase 8052.AA CAMK-Unique 50-307 28 1.2e-98 326.34 In-house 1-363 (363) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-363/363
Sequence Identity: 28% (104 aa)

YTLMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKPEEQKQ------------------LIEEFNILKQLDHPNIIKVYEV----FQDNK------
|.. .. .|.|..|.|...  ..||  .|.|.. |   . . |||                  | .| .|.| .|||||||.|..    |.| |      
YKMHRI-IGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------FLYIVTELCTGGELFDRIIE--------------------YKHFNE--KEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNK----
          .|||.|.|.||.||| |..                      ||.|   ... .| ..| |..|.|...|||||||.||... .  |    
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------DSILKLVDFGTSTVFDPSLKMS---QKLGTPYYIAP--------------EVLR-HKYNEKC----DVWSCGVIMYILLCGYPPFNAARDE
         .. .|| ||| .. .. . . .      |||.|.||              ||.  ..| ..|    | ||.|||||..|||.|||... ..
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------DIMKKVEKGVF-TFPKDDWKD---ITIEAQQMICKMLTMDPQKRYSAEEALQDPWI
         | ..  || . .|... | .   |. || . . . .| || .| ||.|.|. .||
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 8052.AA Pkinase 50-307 35 6.4e-98 336.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-307
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YTLMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKPEEQKQLIE--EFNILKQLDHPNIIKVYEVFQDNKFLYIVTELCTGG----ELFDRII--E
|..   ..|.||.|.|.|..||.||.. |||||.|.  |........   |  |.| |.||||.. |..|.|.. .|.|.|.| ||    .|||.|   .
YHIG-RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

YKHF--NEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLD-SKNKDSILKLVDFGTSTV--FDPSLKMSQKLGTPYYIAPEVLR--HKYNEKCDVWS
.. |   |.|. ..||||| ...|.|...|.||||||||.|.|   . |...|. ||| . .    ..  |.   |||.|.||||.|   .|  |.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGVIMYILLCGYPPFNAA------RDEDIMKKVEKGVFTFPKDDWKDIT-----------------IEAQQMICKMLTMDPQKRYSAEEALQDPWI
||.|.|..|||.|||  .      ..  ..... .. . |. . | .|                   |... |...|..||.||..||..||.||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 8052.AA Ciliate-E2 51-307 28 1.8e-96 326.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 51-307
Range on HMM: 1-365/365
Sequence Identity: 28% (110 aa)

TLMNVPLGKGSYGEVRKGVHKKTGQQ-----------------------RAVKIIDKS--QCKPEEQKQLI---------EEFNILKQLDHPNIIKVYEV
   .  .|.|..| |.|. ..|...|                        |.||. |.  . .  |....          .| |||.||.|||||| ||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DNKFLYIVTELCTGGELFDRII------------EYKHFNEKEAADVMYQILN---------------AINYLHKNK-IVHRDLKPENLLLDSKNK
||  |.. .|.|.|.| ||.|||.|.            . | |.|||....|.|||.               |..|||... |.|||.||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

DSILKLVDFGTSTVFDPS-----------LKMSQK----------------------LGTPYYIAPEVLRHK----------YNEKCDVWSCGVIMYILL
   .|..|||.|. .|..           ..|  |                      .|||.| |||.|. |          |..|||.||.|||.|..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

CGYPPFNAARDEDIMKKVEKGVFTFPKD--------------DWKDITIEAQQMICK----MLTMDPQKRYS-AEEALQDPWI
.|.|||        ... ... . ||.               .||... |....| |    ||  ||.||.. .|..|. ||.
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 8052.AA RSK 53-307 35 1.3e-93 317.31 In-house 1-278 (278) Show / Hide 
Range on Protein: 53-307
Range on HMM: 1-278/278
Sequence Identity: 35% (100 aa)

MNVP--LGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKPEE--QKQLIEEFNILKQLD-HPNIIKVYEVFQDNKFLYIVTELCTGGELFDRIIEYKH---
. |   .|.|..  .|| .|..|||. |.|...|.  .. .  ..   .| |||.    ||.|.. ...||... ||...|.| |||||... . ||   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKD-SILKLVDFGTSTVFDPS-LKMSQK-LGTPYYIAPEVLR----HK-YNEKCDVWSCG
| |.||...|..|  |. .||. .|.|||||||| |.|... .   .||.||| .  |...  .. ..  .|  |.|||.|.     . ... ||.|| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIMYILLCGYPPFNA---ARDEDIMKKVEKGVFTFPKDDWKDITIEAQQMICKMLTMDPQKRYS-----AEEALQDPWI
|.|| .| |.||| .   .  ..|||...|| |... . |. .. ||.  | |||..||.||..     ||| .|.||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 8052.AA MARK 52-307 36 1e-91 300.09 In-house 2-262 (262) Show / Hide 
Range on Protein: 52-307
Range on HMM: 2-262/262
Sequence Identity: 36% (98 aa)

LMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKP-EEQKQLIEEFNILKQLDHPNIIKVYEVFQ--DNKF-LYIVTELCTGGELFDRIIEY--KHF
 |   .|.|||..|....||.||.. |.||..| .  . .. | .  | .|.|.|||||||| ..|..  ...  .|.. |.. ||||.|.|..    . 
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

NEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDSILKLVDFGTSTVFDPSLKMSQKLGTPYYIAPE-VLRHKYN-EKCDVWSCGVIMYILL
 |.||     ||. |.||.|.. |||||.||||.|.|....  | |. ||| |. . |  | .   ||| | ||| .|. .|.  | |.||.||..|...
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNI-KIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGYPPFNAAR--DEDIMKKVEKGVFTFPKDDWKDITIEAQQMICKMLTMDPQKRYSAEEALQDPWI
||| || ..   .....||. .|....|      .  |....|...|| .| .| ..|| ...||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 8052.AA Pkinase_Tyr 51-174 30 3.8e-24 82.41 Pfam 1-137 (270) Show / Hide 
Range on Protein: 51-174
Range on HMM: 1-137/270
Sequence Identity: 30% (42 aa)

TLMNVPLGKGSYGEVRKGVHK----KTGQQRAVKIIDKSQCKPEE--QKQLIEEFNILKQL-DHPNIIKVYEVFQ-DNKF--LYIVTELCTGGELFDRII
  ..  ||.|..|||.||. |    .|... |||.. | .. .|.  .. ...| .|.||| .||||.. | |   . .   .|||.|.. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EY----KHFNEKEAADVMYQILNAINYLHKNKIVHRDL
.     .... |.  .  .|| .. .||. ....||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 8052.AA TyrKc 51-310 24 1.7e-20 75.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 51-310
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

TLMNVPLGKGSYGEVRKGVHKKTGQQRAVKIIDKSQCKPEEQKQLIEEFNILKQL--DHPNIIKVYEVFQDN-------KFLYIVTELCTGGELFDRIIE
  ..  || | .|||.||. |   .| ||| . ..      .. ...| .|...|  .||||.. | |  .        . |.||.|.. .| | |.. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YKH-FNEKEAADVMYQILNAINYLHKNKIVHRDLKPENLLLDSKNKDSILKLVDFGTSTVFDPS--------LKMSQK--LGTP----YYIAPEVLRHK-
... .. |.  . ..|| .  .|||.....||||   | |.....   . |  ||| |   .           .....   |         |||..... 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YNEKCDVWSCGVIMY-ILLCGYPPFNA-----ARDEDIMKKVEKG-VFTFPKDDWKD-----ITIEAQQMICKMLTMDPQKRYSAEEALQDPWIKKF
...| |||| || |. |.  | .|          .......|..|     |..|         . |  |.. .    || .| . .|      ...|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase 8052.AA Pkinase_Tyr 218-264 33 1.658055 2.34 Pfam 182-232 (270) Show / Hide 
Range on Protein: 218-264
Range on HMM: 182-232/270
Sequence Identity: 33% (17 aa)

APEVLRH-KYNEKCDVWSCGVIMYILLC-GYPP-FNAARDEDIMKKV-EKG
|||.... |...| |||| || |. ..  |  | .    .|...... |.|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
EFh 8052.AA EFh 357-385 27 9.2e-07 29.71 SMART 1-29 (29) Show / Hide 
Range on Protein: 357-385
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

ELLKTFQSLDTNGDGKLSREELINGYSKI
|. . |. .|..|||... ||.. . ...
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 8052.AA efhand 357-385 34 1e-06 28.83 Pfam 1-29 (29) Show / Hide 
Range on Protein: 357-385
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

ELLKTFQSLDTNGDGKLSREELINGYSKI
|| . |. .|..|||....||......|.
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 8052.AA EFh 394-422 27 6.1e-05 23.67 SMART 1-29 (29) Show / Hide 
Range on Protein: 394-422
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

EVDKIMKVIDKNDNGDIDYSEWVAATISR
|........||. .| ||. |....  | 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 8052.AA efhand 394-422 27 6.1e-05 22.49 Pfam 1-29 (29) Show / Hide 
Range on Protein: 394-422
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

EVDKIMKVIDKNDNGDIDYSEWVAATISR
|.....|..||. .| ||. |....  . 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 8052.AA efhand 430-458 37 1.2e-05 25.14 Pfam 1-29 (29) Show / Hide 
Range on Protein: 430-458
Range on HMM: 1-29/29
Sequence Identity: 37% (11 aa)

RLEMAFNIFDKDGSGSLQLSEFKEIFGGA
.|. .|..|||||.| . . ||.|..   
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 8052.AA EFh 430-458 34 2e-05 25.29 SMART 1-29 (29) Show / Hide 
Range on Protein: 430-458
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

RLEMAFNIFDKDGSGSLQLSEFKEIFGGA
 ....|..|||||.| . . |||...   
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 8052.AA efhand 464-492 51 4.6e-09 37.6 Pfam 1-29 (29) Show / Hide 
Range on Protein: 464-492
Range on HMM: 1-29/29
Sequence Identity: 51% (15 aa)

VWKAVIKEVDKNGDGEISYQEFKEMMLKY
 .|...||.||.|||.|...||.||| | 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 8052.AA EFh 464-492 41 1.3e-08 35.83 SMART 1-29 (29) Show / Hide 
Range on Protein: 464-492
Range on HMM: 1-29/29
Sequence Identity: 41% (12 aa)

VWKAVIKEVDKNGDGEISYQEFKEMMLKY
 .|......||.|||.|...|||.|| . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL