Gene 28485 (Tetrahymena)

28485

Species: Tetrahymena
Alias: PreTt28485, 28485, TTHERM_00160930, 13.m00444, 126, 3829.m01304
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CDPK

Sequence

Name Sequence Type Origin Length Description Download
28485.AA Protein None 506 None Fasta, JSON
28485.kin_dom Protein Kinase Domain None 257 None Fasta, JSON
28485.NA RNA None 1521 None Fasta, JSON

Protein domain

Protein domains of 28485.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28485.AA CDPK 55-311 61 4.8e-206 637.62 In-house 1-271 (271) Show / Hide 
Range on Protein: 55-311
Range on HMM: 1-271/271
Sequence Identity: 61% (166 aa)

QLLNPPLGKGAFGEVRKCVHK-ATNLTR-AVKIISKAQTPKAEQ-DRLKQEVEILKQLDHPNIIKIYEFYQDQKYFYIVTE--LCTGGELFDKIIEERSF
. ....||||.||.|||..|| .|| .| |.|||.| . ...|| .....|.||||||||||||||||||||.|..|||.|  .||||||||.|||...|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

DERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGA----LLKVVDFGTSLAYDPN-----VKMNQKLGTPYYIAPEVLSKKYDEKCDIWSCG
.|...|..|||||.||||||.||||||||||||||..|.|...     .||.|.|||  .|.|      ||.|..||||||||||| |||.|||||||||
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG

VILYILLCGSPPFNGENDEQIMNRVKIGKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLSAQDVLNDPWL
|||||||||.|||.|.||..||. || ||.||. ..|. ||| || || |||..|| ||.|||..|..|| 
VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 28485.AA CAMK1 54-311 45 2.9e-164 481.45 In-house 1-276 (276) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-276/276
Sequence Identity: 45% (125 aa)

YQLLNPPLGKGAFGEVRKCVHKAT---NLTRAVKIIS-KAQTPKAEQ---DRLKQEVEILK---QLDHPNIIKIYEFYQDQKYFYIVTELCTGGELFDKI
|.. .  .|.|||.||..|.|| |   .   |.|.|. | .. | ..   ..|..|.||.|   ..|||||||.||.|.. ..||.|.||.|||||||.|
YEFGK-EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

IEERSFDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGALLK--VVDFGTSLAYDPNV-KMNQKLGTPYYIAPEVLSKK----YDEKCDI
.|  .. |.. ...|.|||.||.|.|...||||||||||.||....... .|  . ||| |  .|... .| .  |||.|.|||||  |    || .||.
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

WSCGVILYILLCGSPPFNGEN-DEQIMNRVKIGKFSFDSEDWAGISDG-AKSLIAKMLEKDPTKRLSAQDVLNDPWL
||.|||.|||||| |||..|| |....  .| ... |.|  |  |||. || .| .|||.||.||......||.||.
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 28485.AA CAMK 60-311 30 2.9e-137 445.17 In-house 1-425 (425) Show / Hide 
Range on Protein: 60-311
Range on HMM: 1-425/425
Sequence Identity: 30% (131 aa)

PLGKGAFGEVRKCVHKATN-LTR-----------AVKIISKAQTP--------------------------KAEQDRLKQEVEILKQ-------LDHPNI
 ||.|.||.|..|.|| |. ..|           |.|||.| . .                             ......|.||.|.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKIYEFYQD-------------------QKYFYIVT---ELCTGGEL----FDKIIEE---------------RSFDERKTAETMRQILQAVNYCHKNNI
||.||.|.|                   .|..|.|.   |.|.||||    ||.|.|                . |.|| ..  .|||..||.|||..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENILYESNKPG--------------ALLKVVDFGTSLAYDP------------------------NVKMNQKLGTPYYIA-PEVLSKK-----
|||||||||||. .|...              . .|..||| .  .||                        . ||.   |||.|.| ||||..|     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDEKCDIWSCGVILYILLCGSPPFNGE-------------NDEQIMNRVKIGKFSFDSED------------WAGISDG--------AKS
          |..|||.|||||||||.||| |||.|.             ||.... ... ||..|...             | .|||         .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIAKMLEKDPTKRLSAQDVLNDPWL
|| |||..||.||......||.||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 28485.AA Ciliate-E2a 54-311 44 1.1e-136 404.86 In-house 1-275 (275) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-275/275
Sequence Identity: 44% (123 aa)

YQLLNPPLGKGAFGEVRKCVHKATNLT-RAVKIISKAQTPKAEQDRLKQEVEILKQLDHPNIIKIYEFYQDQKYFYIVTELCTGGELFDKIIEERSFDER
| ...  .|||.|| |..  || |.   ...|.| |..  | ..  ...|. |..|||||||||.||.|.| ...|.|.|.| ||||.|||..  .|.| 
YKFIK-KIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--KTAETMRQIL-QAVNYCHKNNIVHRDLKPENILYE---SNK-PGALLKVVDFGTSLAYDPNVK--MNQKLGTPYYIA------PEVLSKK-YDEKCDI
  . .. |.|.| |...|.|..||.||||||||||..   .|. . . .|..|||..  .|.. |  | || |||.|.|      .|||..| ||.|||.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSCGVILYILLCGSPPFNGENDEQIMNRVKIGKFSFDSED-WAGISDGAKSLIAKMLEKDPTKRLSAQDVLNDPWL
||||||.||||||.|||.|.. ..|   .|  |..|.. . |  .|. .| |. ||||||| ||..||. ||.|| 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 28485.AA S_TKc 54-311 38 4.1e-108 366.41 SMART 1-231 (231) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-231/231
Sequence Identity: 38% (105 aa)

YQLLNPPLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQDRLKQEVEILKQLDHPNIIKIYEFYQDQKYFYIVTELCTG--GELFDKIIEERS---
|..|. ..||||||.|.||.|| |.   |.|||.         .....|..|||. .||||.|.|...|| ...|.|.|.| |  |.||| | . ..   
YEILR-KIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGALLKVVDFGTSLAYDPNVKMNQKLGTPYYIAPEVLSKKYDE-KCDIWSCGVILY
   |.|  ..  |.||..|..|||...|.||||||||||  .      .|. ||| .  .      .   |||.|.|||||  .|.  |||.||||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY

ILLCGSPPFNGENDEQIMNRVKIGKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLSAQDVLN-------DPWL
..||| |||   ..........              |. ||..| |.|.|||.||..| ..|.       .||.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 28485.AA RAD53 56-311 38 2.4e-107 320.88 In-house 2-305 (305) Show / Hide 
Range on Protein: 56-311
Range on HMM: 2-305/305
Sequence Identity: 38% (117 aa)

LLNPPLGKGAFGEVRKCVHKATNLTRAVKIISK---A---QTPKAEQDRLKQEVEILKQLDHPNIIKIYEFYQD-QKYFYIVTELCTGGELFDKII-EER
...  ||.|.||.|.... | |  . |.|||.|   .    .  .  |..  |||||| | ||.||.||..... |||.|.| || ||||||.||.  .|
YMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNKR

S---FDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGA---------------LLKVVDFGTSLAYDPNVKMNQKLGTPYYIAPEVLSKK
    ||| .  .. .|.. ||.| | |.|.||||||||||..... .                |.|. ||| | . .    |.   ||| | ||||. .|
CQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITSK

----------------YDEKCDIWSCGVILYILLCGSPPFNGEND-----EQIMNRVKI-GKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLSAQDVLN
                |  |.|.|| |.||||.||| |||  . .      |.   .|  ||..|....|. ||. ||.|| .||  ||.||... ..||
GHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEALN

DPWL
 ||.
HPWM
Kinase 28485.AA CAMKL 54-311 35 1.5e-104 334.6 In-house 1-297 (297) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-297/297
Sequence Identity: 35% (107 aa)

YQLLNPPLGKGAFGEVRKCVH-KATNLTRAVKIISKAQTP--------------KAEQDRLKQEVEILKQLD---HPNIIKIYEFYQDQKY------FYI
|...   ||||.||.|. ..| . |.   |.||| |  .               .. . |...|..|.|.|.   ||||||.|| ......      .|.
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL

VTELCTGGE--LFDKIIEE----RSFDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNK-PGALLKVVDFGTSLAYDP-----NVKMNQKLGT
|.|.| |||  |||.|...    ....|. .    |||. ||||||...|||||.||||||  .|.     .|..||| |  |.|     . |..   |.
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGS

PYYIAPEVLSK--K-YD-EKCDIWSCGVILYILLCGSPPFNGENDE-------QIMNRVKIGKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLSAQDVL
| | |||....  | ||  | |||||||||| ..||  ||......         ......| . ..   |  .|  ...|| |||...|.|| ......
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

NDPWL
|.||.
NHPWM
Kinase 28485.AA CAMK-Unique 54-311 29 1.7e-103 342.55 In-house 1-363 (363) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-363/363
Sequence Identity: 29% (107 aa)

YQLLNPPLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQDR------------------LKQEVEILKQLDHPNIIKIYEF----YQDQK------
| ... ..|.|.||.|..|  ..|   .|.|.. |.      |.                   || |..|.| .|||||||.|..    ..| |      
YKMHR-IIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------YFYIVTELCTGGELFDKIIE--------------------ERSFDE--RKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKP----
         |.|||.|.|.||.|||.|..                    ...| |  . |.  |...|.||.| |...|||||||.|||.. .. .    
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------GALLKVVDFGTSLAYDPNVKMN---QKLGTPYYIAP--------------EVLS-KKYDEKC----DIWSCGVILYILLCGSPPFNGENDE
            .|. ||| .  |. | .        |||.|.||              ||.   .||..|    ||||.|||.|..|||.|||..|...
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------QIMNRVKIGKF-SFDSEDWAG---ISDGAKSLIAKMLEKDPTKRLSAQDVLNDPWL
         |  . ..|.. .||.. | |   ||..||... . .. || .|.||   |  .|.
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 28485.AA Pkinase 54-311 36 5.69999999999e-101 346.54 Pfam 1-293 (293) Show / Hide 
Range on Protein: 54-311
Range on HMM: 1-293/293
Sequence Identity: 36% (109 aa)

YQLLNPPLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQDRLKQ--EVEILKQLDHPNIIKIYEFYQDQKYFYIVTELCTGG----ELFDKII--E
|...  ..|.|.||.|.||.|| |. . |||||.|  . . .. ..    |..|.| |.||||...|....| .. |.|.|.| ||    .||| |   .
YHIG-RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ERSF--DERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYE-SNKPGALLKVVDFGTSLA--YDPNVKMNQKLGTPYYIAPEVLS--KKYDEKCDIWS
...|  .|.     |.|||....|||...|.||||||||||.   . ..| .|. ||| .    | .|. |.   |||.|.||||.   ..|. |.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGVILYILLCGSPPFNGE------NDEQIMNRVKIGKFSFDSEDWAGIS-----------------DGAKSLIAKMLEKDPTKRLSAQDVLNDPWL
||.|||..||| ||| |.      .. |...|.. ....||.. |  ||                 . .|..| ..|.|||.||..|...|..||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 28485.AA MAPKAPK 55-311 36 3.3e-100 310.99 In-house 1-292 (292) Show / Hide 
Range on Protein: 55-311
Range on HMM: 1-292/292
Sequence Identity: 36% (108 aa)

QLLNPPLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQDRLKQEVEILKQL-DHPNIIKIYEFYQD----QKYFYIVTELCTGGELFDKIIE--ER
.| .  || |. | |..|||| |.   ||||. .   |     .  .|||....  .||||..| ... .    .| ||.| |.  |||||..| .  ..
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQ--PGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHK

SFDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGALLKVVDFGTSLA-------YDP--NVKMNQKLGTPYYIAPEVL-SKK----YDEK
 | ||. .. |..| .|| ..|. || ||||||||||...... . .|  |||            .|  ....    .||||.||||.   |    || .
HFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKS

CDIWSCGVILYILLCGSPPFNGEND----------------EQIMNRVKIGKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLSAQDVLNDPWL
||.|| |||.||.||| ||| .. .                ..  .| . |...| .|.|. ||. || || |.| .|||.||....|.| ||.
CDMWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase 28485.AA Ciliate-E2 55-311 30 2.3e-97 329.78 In-house 1-365 (365) Show / Hide 
Range on Protein: 55-311
Range on HMM: 1-365/365
Sequence Identity: 30% (116 aa)

QLLNPPLGKGAFGEVRKCVH-----------------------KATNLTRAVKIISKAQTPKAEQ-DRLKQEVE----------ILKQLDHPNIIKIYEF
  ..  .|.|.|| |.|| .                       |...   |.||..| |    .| ... .|..          ||.||.||||||.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YQ--DQKYFYIVTELCTGGELFDKII------------EERSFDERKTAETMRQILQ---------------AVNYCHKNN-IVHRDLKPENILYESNKP
.|  |....|.|.|.| ||.||| |.            .  .|.|.. .. |.||||               |..|.|..| |.|||.||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

GALLKVVDFGTSLAYDPN-----------VKMNQK----------------------LGTPYYIAPEVLSKK----------YDEKCDIWSCGVILYILL
   .|..|||.|  ||..            .|. |                      .|||.| |||.|..|          ||.||||||.|||||..|
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

CGSPPFNGENDEQIMNRVKIGKFSFDSE--------------DWAGISDGAKSLIAK----MLEKDPTKRLS-AQDVLNDPWL
.| |||        ..  | .|..|...              .|  .|. .| || |    ||.||| ||.. ....|| ||.
FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 28485.AA RSK 56-311 35 1.5e-94 320.47 In-house 1-278 (278) Show / Hide 
Range on Protein: 56-311
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

LLNP-PLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQD--RLKQEVEILKQLD-HPNIIKIYEFYQDQKYFYIVTELCTGGELFDKIIEERS---
|    ..|.|..  .|||.|..|.   |.|...||   ... |  . ..|..||.    ||.|.. .. .|.....|...|.| |||||... .|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPG-ALLKVVDFGTSLA--YDPNVKMNQKLGTPYYIAPEVLS----KK-YDEKCDIWSCG
|.|.  .. |..|  || . |.  |.|||||||||||.. . . . .|..||| .     | | ...   .|  |.|||.|     .. .|. ||.|| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYILLCGSPPFNG---ENDEQIMNRVKIGKFSFDSEDWAGISDGAKSLIAKMLEKDPTKRLS-----AQDVLNDPWL
|..| .| | ||| |   .| ..||.|.. ||||.... |. .|. ||.|| |||..|| |||.     |......||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 28485.AA Pkinase_Tyr 54-178 28 2.4e-21 72.9 Pfam 1-137 (270) Show / Hide 
Range on Protein: 54-178
Range on HMM: 1-137/270
Sequence Identity: 28% (40 aa)

YQLLNPPLGKGAFGEVRKCVHK----ATNLTRAVKIISKAQTPKAE--QDRLKQEVEILKQL-DHPNIIKIYEFYQ-DQKY--FYIVTELCTGGELFDKI
 ...   ||.||||||.|.. |     |... |||.. | .. . .  .. . .|..|.||| .||||.. |     ...    |||.|.. .| | |  
ITFGKK-LGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

IE----ERSFDERKTAETMRQILQAVNYCHKNNIVHRDL
 .    .....     .  .|| .. .| . .|..||||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 28485.AA TyrKc 55-309 23 3.1e-17 56.04 SMART 1-280 (280) Show / Hide 
Range on Protein: 55-309
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

QLLNPPLGKGAFGEVRKCVHKATNLTRAVKIISKAQTPKAEQDRLKQEVEILKQL--DHPNIIKIYEFYQDQ-------KYFYIVTELCTGGELFDKIIE
  |.  || ||||||.|.. |   .. ||| . .       .  . .| .|...|  .||||...|    .|       .  .||.|.. .| | | . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ERS-FDERKTAETMRQILQAVNYCHKNNIVHRDLKPENILYESNKPGALLKVVDFGTSLAYDPN--------VKMNQK--LGTP----YYIAPEVL-SKK
 |  .  ..  . . || .  .| |..|..||||   |.|. .|.     |. ||| | . .          ... ..   |         |||..  .|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDEKCDIWSCGVILY-ILLCGSPPFNG-----ENDEQIMNRVKIGKFSFDSED-----WAGISDGAKSLIAKMLEKDPTKRLSAQDVLNDP
. .| |.|| || .. |.  | .|  |      ........|| |.     ..       . .|   ... .  . || .| . ...  . 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Efhand 28485.AA efhand 361-389 34 2e-06 27.79 Pfam 1-29 (29) Show / Hide 
Range on Protein: 361-389
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

ELLKVFQSLDTNNDGKLQREELIQGYKKI
|| ..|. .|...||.. .||.....||.
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 28485.AA EFh 361-389 27 3e-06 28.23 SMART 1-29 (29) Show / Hide 
Range on Protein: 361-389
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

ELLKVFQSLDTNNDGKLQREELIQGYKKI
|. ..|. .|...||..  ||.... |..
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 28485.AA efhand 398-426 24 9.5e-05 21.8 Pfam 1-29 (29) Show / Hide 
Range on Protein: 398-426
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

EVDKILTVVDKNQSGEIDYSEWVAATINR
|....  ..||...|.||. |....  . 
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 28485.AA EFh 398-426 24 0.000531 20.54 SMART 1-29 (29) Show / Hide 
Range on Protein: 398-426
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

EVDKILTVVDKNQSGEIDYSEWVAATINR
|....  ..||. .|.||. |....  . 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
EFh 28485.AA EFh 434-462 34 3.6e-08 34.38 SMART 1-29 (29) Show / Hide 
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

RLELAFKMFDQDGSGTVTKDELKQMFQGM
 .. .|.|||.||.|.....|.|.|.. .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL
Efhand 28485.AA efhand 434-462 34 4.3e-08 34.04 Pfam 1-29 (29) Show / Hide 
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

RLELAFKMFDQDGSGTVTKDELKQMFQGM
.|. .||.||.||.|.....|...|.. .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
Efhand 28485.AA efhand 469-497 48 5.7e-08 33.6 Pfam 1-29 (29) Show / Hide 
Range on Protein: 469-497
Range on HMM: 1-29/29
Sequence Identity: 48% (14 aa)

VWKQLLNEVDDNGDGQISYKEFKEMMLKL
 .|.. .|.| .|||.|...||.||| ||
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL
EFh 28485.AA EFh 469-497 41 1.2e-07 32.63 SMART 1-29 (29) Show / Hide 
Range on Protein: 469-497
Range on HMM: 1-29/29
Sequence Identity: 41% (12 aa)

VWKQLLNEVDDNGDGQISYKEFKEMMLKL
 .|.. ...| .|||.|...|||.|| .|
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL