Gene 2173 (Tetrahymena)
2173
Sequence
Protein domains of 2173.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | 2173.AA | S_TKc | 1099-1331 | 26 | 3.9e-59 | 203.68 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1099-1331 Range on HMM: 1-231/231 Sequence Identity: 26% (73 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVINERNLLCTLKHPFLVNMFYAFQDRDNLFLVMDFMSG--GDLRFHIGKQRR--- . . .||||.||||.|. .|| .|.|.|... .....|...| .||..|.....||| |.|..||....| |||. .| |..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FNEEQTK--------------------------NLVLDDDGYVRITDLGIARNWKPDNQNDTSGTPGYMAPEVMCRQPHTF-AVDYFALGVIAFEFM |.| ... |. ||. . |.| |.|| . ||| ||||||. .... ..| ..|.| .|.. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML LGRRPYLGRSRQEIRNQILARRVQIKKNEIPDGWSLEAADFINKLIERKPAQRLGINGPDE----VKNHPWL |. |. |.. ..|. | || |||.|. .. |..|... . .|.|||. CGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 2173.AA | AGC | 1201-1331 | 23 | 4.3e-53 | 134.53 | In-house | 185-395 (395) | Show / Hide |
Range on Protein: 1201-1331
Range on HMM: 185-395/395
Sequence Identity: 23% (50 aa)
NLVLDDDGYVRITDLGIARN--------------------------------------WKPDN--------------QNDTSG--TPGYMAPEVMCRQPH
|..||.||....|| | . |. .| . | || |||||. .
NILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----Y
TFAVDYFA--LGVIAFEFMLGRRPYLGRSRQ----------EIRNQILARR-VQIKKNEIP----------DGWSLEAADFINKLIERKPAQRLGIN---
..|.|. . ||.. .|.. |. |. | ..| |. ..|. .| .. .| ..| . .| || |.|.||... |..||| .
GKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGND
----GPDEVKNHPWL
| .|.|||||
FGDKGAEEIKNHPWF
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| Kinase | 2173.AA | Ciliate-E2-Unclassified | 1201-1331 | 25 | 4.8e-52 | 178.82 | In-house | 174-352 (352) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 174-352/352 Sequence Identity: 25% (46 aa) NLVLDDDG---YVRITDLGIAR-----------------NWKPDNQNDTSGTPGYM----APEVMCRQPHT----FAVDYFALGVIAFEFMLGRRPYLGR |...|..| |..|.|.||.. .||........|||.|| ||||...| . ...|...||||..|.. |..|. .. NILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDN SRQE----------------IRNQILARRVQIKKNE---IPDGWSLEAADFINKLIERKPAQRLGIN-GPDEVKNHPWL .. . ....|... .|..| . ||..|| ||.||||.|. ... ... . ......||||. NCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 2173.AA | AGC | 1099-1200 | 32 | 5.8e-51 | 128.89 | In-house | 240-388 (395) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 240-388/395 Sequence Identity: 32% (48 aa) FNFQFVIGKGGFGKVWKVEQR------KTRQIFAMKEMSKSL-IITKK--SVNSVINE------------RNLLCTLK----------HPFLVN-MFYAF |.| |||||.||||. |. . | ...||| ..|. |. || | ...| || | ... |||.|. ..|.| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDRDN--LFLVMDFMS---------GG-DLRFHI-G--KQRRFNEEQTK || |. |..||..|. || .| .|. | |..||.||... QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERAR |
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| Kinase | 2173.AA | Akt | 1099-1200 | 43 | 9.4e-41 | 127.94 | In-house | 1-103 (264) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 1-103/264 Sequence Identity: 43% (45 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIF-AMKEMSKSLIITKKSVNSVINERNLLCTLKHPFLVNMFYAFQDRDNLFLVMDFMSGGDLRFHIGKQRRFNEE |.| |.||| |||| |.. .| ... ||| .|. || |. | .. |||.| . .|||.||. |.||. |.|..|||...||.| .|. ..|||.|. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED QTK ... RAR |
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| Kinase | 2173.AA | SGK | 1099-1200 | 32 | 1.8e-39 | 119.22 | In-house | 1-128 (283) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 1-128/283 Sequence Identity: 32% (42 aa) FNFQFVIGKGGFGKVWKVEQRKT------------------RQIFAMKEMSKSLII-------TKKSVNSVINER-NLLCTLKHPFLVNMFYAFQDRDNL | | |||||.|||| |. .. ...||| .| || ||... . || ..| .||||.|| |||| . | FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL FLVMDFMSGGDLRFHIGKQRRFNEEQTK ..|||.. ||.. .|. . ..| | . . YFVMDYVNGGEMFYHLQREKHFPEDRAR |
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| Kinase | 2173.AA | Ciliate-E2 | 1201-1331 | 21 | 8.2e-39 | 130.86 | In-house | 191-365 (365) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 191-365/365 Sequence Identity: 21% (41 aa) NLVLDDDGYVRITDLGIAR---------------NWKPDNQNDT-------------------SGTPGYMAPEVMCRQP---------HTFAVDYFALGV |... . |.|.|... .|... .||| |||||||||. ... .....|...||| NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGV IAFEFMLGRRPYLGRSRQEIRNQILARRVQIKKNE-------------IPDGWSLEAADFINK----LIERKPAQRLGINGPDEVKNHPWL | .|.. |..|. .||. ... ..| ... ||.|. |.|.| .....| .|.. |.....||||. ILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF |
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| Kinase | 2173.AA | Ciliate-E2-Unclassified | 1099-1200 | 30 | 1.9e-37 | 127.44 | In-house | 265-405 (352) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 265-405/352 Sequence Identity: 30% (43 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSV---------INERN-------------LLCTLKHPFLVNMFYAFQDRDNLFLVM .... .||.||||||.|....|. |..|||.|.|. |. .|..... .|... .| ..|||.|.|||.|||..|...|| YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM DFMSGGDLRFHIGKQ-----------------RRFNEEQTK ... ||||...| |. ..| |.|.| EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAK |
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| Kinase | 2173.AA | MAST | 1099-1183 | 42 | 2.1e-37 | 111.37 | In-house | 169-255 (337) | Show / Hide |
Range on Protein: 1099-1183 Range on HMM: 169-255/337 Sequence Identity: 42% (37 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVINERNLLCTLKHPFLVNMFYAFQD--RDNLFLVMDFMSGGD |.| .|.||..|.|..|. .||...|||| . .. .| |. |..|. ||| | .. || |.|||.|| .. |..||..|.||| FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGD |
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| Kinase | 2173.AA | MAST | 1099-1188 | 44 | 1.1e-35 | 112.31 | In-house | 143-232 (334) | Show / Hide |
Range on Protein: 1099-1188 Range on HMM: 143-232/334 Sequence Identity: 44% (40 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVINERNLLCTLKHPFLVNMFYAFQDRDNLFLVMDFMSGGDLRFHI |.| .|.||..|||..|. .||...|||| . || | |. |..|. ||| | .. || |.|||.|| ...|..||..|.|||. ... FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLL |
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| Kinase | 2173.AA | Ciliate-E2 | 1099-1200 | 27 | 1.3e-35 | 119.67 | In-house | 122-269 (365) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 122-269/365 Sequence Identity: 27% (40 aa) FNFQFVIGKGGFGKVWKVEQRKTR-----------------------QIFAMKEMSKSLIITKKSVNSVI----------NERNLLCTLKHPFLVNMFYA ..|. .||.|.||.|.|....|.. .|.||| |.|. |. .|...... ||.|.| .|.||....|... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DRDNLFLVMDFMSGGDLRFHIGKQR-----------RFNEEQTK || |..|..|||.. .||||. .| ... .|.|.. | FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIK |
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| Kinase | 2173.AA | PKC | 1099-1200 | 44 | 1.3e-34 | 109.54 | In-house | 1-103 (262) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 1-103/262 Sequence Identity: 44% (46 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVINERNLLCTL-KHPFLVNMFYAFQDRDNLFLVMDFMSGGDLRFHIGKQRRFNEE |||. |.||| |||| .|...|....|.| . | .|| | .. .|. | . |||||.... || |.|| || . |||| ||| .||||.|| FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE QTK ... HAR |
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| Kinase | 2173.AA | AktR | 1099-1200 | 36 | 6e-34 | 119.11 | In-house | 1-104 (268) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 1-104/268 Sequence Identity: 36% (38 aa) FNFQFVIGKGGFGKVWKVEQR-KTRQIFAMKEMSKSLIITKKSVNSVINERNLLC-TLKHPFLVNMFYAFQDRDNLFLVMDFMSGGDLRFHIGKQRRFNE | . ..|||.|||| |. . .. ...||| .|. || .. .|.||| . .|||.|...|.||....||..|... ||.| .|. |...|.| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE EQTK ||.. EQAR |
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| Kinase | 2173.AA | Akt | 1201-1331 | 34 | 1.5e-31 | 98.02 | In-house | 131-264 (264) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 131-264/264 Sequence Identity: 34% (47 aa) NLVLDDDGYVRITDLGIAR-N-WKPDNQNDT-SGTPGYMAPEVMCRQPHTFAVDYFA-LGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKKNEIPDG |...| ||....|| | .. | | . .| ||| |.|||. . || ||| . ||.. .|.| || |. . ... .|. |..... | NILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDK---DW WSLEAADFINKLIERKPAQRLG--INGPDEVKNHPWL .| |. |.|..| .. | .||| .|. .|.|.|||. ISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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| Kinase | 2173.AA | SGK | 1201-1331 | 35 | 4.4e-31 | 92.88 | In-house | 155-283 (283) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 155-283/283 Sequence Identity: 35% (47 aa) NLVLDDDGYVRITDLGIAR-NWKPDNQNDT-SGTPGYMAPEVMCRQPHTFAVDYFALGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKKNEIPDGWS |..||..|....|| | . . |. . | ||| |.||||. ||| .|| . || . .|.| | |. | .|. .|. ||... | NILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQ-----MS LEAADFINKLIERKPAQRLGIN-GPDEVKNHPWL .| | |. | .. | .||| . . |.||||. NDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF |
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| Kinase | 2173.AA | MAST | 1231-1331 | 37 | 1.7e-30 | 89.83 | In-house | 230-337 (337) | Show / Hide |
Range on Protein: 1231-1331 Range on HMM: 230-337/337 Sequence Identity: 37% (42 aa) GTPGYMAPEVMCRQP-HTFAVDYFALGVIAFEFMLGRRPYLGRSRQE-IRNQILARRVQIKKNEIPDG--------WSLEAADFINKLIERKPAQRLGIN ||| |.|||| .|. . .||....|.| .|| | | | ...| | ..|. . | | |.. | || | |.|| . | .||| | GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREI---EWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN GPDEVKNHPWL | ||.|.|| GADEIKQHPFF |
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| Kinase | 2173.AA | MAST | 1231-1331 | 40 | 4e-30 | 94.05 | In-house | 226-334 (334) | Show / Hide |
Range on Protein: 1231-1331 Range on HMM: 226-334/334 Sequence Identity: 40% (45 aa) GTPGYMAPEVMCRQP-HTFAVDYFALGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKK-NEIPDG--------WSLEAADFINKLIERKPAQRLGIN |||.|.|||| .|. | .||....|.| .||. | | . ...|| ..|| |. .|.|.| | || | |.|| . | .||| | GTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNC---NEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN -GPDEVKNHPWL | ||||.|| . NGADEVKQHPFF |
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| Kinase | 2173.AA | Pkinase | 1201-1331 | 23 | 4.6e-29 | 103.86 | Pfam | 138-293 (293) | Show / Hide |
Range on Protein: 1201-1331
Range on HMM: 138-293/293
Sequence Identity: 23% (38 aa)
NLVLDDDGYV----RITDLGIAR---NWKPDNQNDTSGTPGYMAPEVMC-RQPHTFAVDYFALGVIAFEFMLGRRPYLGR------SRQEIRNQILARRV
|. .|..|.. .|.| |.|. . . .. |||.|||||| .|... .|| ...|.| .|...|| |. |. . ... ..|. ...
NILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPL
QIKKNEIPD----------------GWSLEAADFINKLIERKPAQRLGINGPDEVKNHPWL
. . || |. |||.......|..|.. ......|||.
HFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
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| Kinase | 2173.AA | RSK | 1201-1331 | 32 | 6.6e-28 | 99.04 | In-house | 134-278 (278) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 134-278/278 Sequence Identity: 32% (49 aa) NLVLDD---DGYVRITDLGIARNWKPD-NQNDTS--GTPGYMAPEVMC---RQP-HTFAVDYFALGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKK | ..|| .| ...|| | .. ..| || . .| |||||. .| |. |.|.. |||. .| |..|. | .... |..|..| |.| NILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKR---IQK NE----IP--DGWSLEAADFINKLIERKPAQRLG--INGPDEVKNHPWL .. .| . | || |.|.|. .| |..||| .. .|.|.|||. GKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 2173.AA | RSK | 1104-1197 | 37 | 3.7e-26 | 92.8 | In-house | 3-104 (278) | Show / Hide |
Range on Protein: 1104-1197 Range on HMM: 3-104/278 Sequence Identity: 37% (38 aa) VIGKGGFGKVWKVEQR---KTRQIFAMKEMSKSLIITK-KSVNSVINERNLLCTLK-HPFLVNMFYAFQDRDNLFLVMDFMSGGDLRFHIGKQRR---FN | |.||.||| . .|.||.||| .|. |... |.. . ||| | . . |||.|. .||||. . |.|.|....||.| |. |... | VLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFS EE |. ED |
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| Kinase | 2173.AA | Pkinase | 1099-1200 | 27 | 2.3e-24 | 87.2 | Pfam | 1-111 (293) | Show / Hide |
Range on Protein: 1099-1200 Range on HMM: 1-111/293 Sequence Identity: 27% (31 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVI-NERNLLCTLKHPFLVNMFYAFQDRDNLFLVMDFMSGG----DLRFHIG--KQ . . .||.|.||.|.| ..|..|.|.|...|. . .| .. . .| .. |.||. | ....|.|.|.. .||... || || .| .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RRF--NEEQTK ..| |.. | GCFYFSEWECK |
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| Kinase | 2173.AA | AktR | 1201-1331 | 33 | 1.2e-23 | 84.87 | In-house | 132-268 (268) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 132-268/268 Sequence Identity: 33% (46 aa) NLVLDDDGYVRITDLGIAR--NWKPDNQNDTS--GTPGYMAPEVMCR-QPHTFAVDYFALGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKKNEIPD |..|| ||.|.||| | .. . . ... .| ||| |||||. . ..|...||. |.|. .| . | | ..... |. . ..|...| NILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ--QNKFPYPS GWSLEAADFIN-KLIERKPAQRLG--INGPDEVKNHPWL | .. |.|. || . | .||| ||..|.|.||| YFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 2173.AA | PKC | 1201-1331 | 28 | 5.8e-23 | 71.11 | In-house | 130-262 (262) | Show / Hide |
Range on Protein: 1201-1331 Range on HMM: 130-262/262 Sequence Identity: 28% (40 aa) NLVLDDDGYVRITDLGIA-RNWKPDNQNDT-SGTPGYMAPEVMCRQPHTFAVDYFALGVIAFEFMLGRRPYLGRSRQEIRNQILARRVQIKKNEIPDGWS | || .| ..|.| | . | ... .| ||| |.|||.. |. ...||. |.|| .|.|.|. | | |. . |. ... .| | NVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPH-----YPRWLS LEAADFINKLIERKPAQRLGI-----NGPDEVKNHPWL ||.. . .. ...|..||| .| .... || KEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF |
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| Kinase | 2173.AA | TyrKc | 1099-1309 | 18 | 7.8e-12 | -31.29 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1099-1309 Range on HMM: 1-280/280 Sequence Identity: 18% (53 aa) FNFQFVIGKGGFGKVWKVEQRKTRQIFAMKEMSKSLIITKKSVNSVINERNLLCTL--KHPFLVNMFYAFQDR-------DNLFLVMDFMSGGDLRFHIG . ..| | ||.|.| . . . | | . .. . ..| ...| | .|| .|... . . . |..|| .|..|||. .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KQRR-FNEEQTK--------------------------NLVLDDDGYVRITDLGIARNWKPD------NQNDTS----GTPG-----YMAPEVMCRQPHT | |. .. .. | ..... |.|.| | .|... | . .. |. . ||||.. | KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT FAVDYFALGVIAFE-FMLGRRPYLG-----RSRQEIRNQILARRVQIKKNE--------IPDG--------WSLEAAD-----FINKLI .. | .. || .| | .| || | | ||..... ... . . || | ...| | ... TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 2173.AA | Pkinase_Tyr | 1099-1185 | 22 | 1.7e-05 | 19.27 | Pfam | 1-95 (270) | Show / Hide |
Range on Protein: 1099-1185 Range on HMM: 1-95/270 Sequence Identity: 22% (22 aa) FNFQFVIGKGGFGKVWKVEQR----KTRQIFAMKEMSKSLIITKKS--VNSVINERNLLCTL-KHPFLVNMFYAFQ-DRDN--LFLVMDFMSGGDLR | ..|.| ||.|.| . . .|.. | | . | ... . ..| .....| .|| .|.. . ... ...|| .| .|||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL |
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| Kinase | 2173.AA | S_TK_X | 1332-1396 | 23 | 0.000438 | 10.97 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 1332-1396 Range on HMM: 1-79/79 Sequence Identity: 23% (19 aa) RNFPWKKLYN--KELQAPFLPSQE----D-----NFD---FKQQISLDDEQT--NEIIQQNAMLLRKPQVQSLFNGYNFDN |.. |.|||| ||...|| | . ||| .....|.. .. ....||. .. . | |..... RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNE-METE-IPPDPFRGFTYVF |
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