Gene 12974 (Tetrahymena)
12974
Sequence
Protein domains of 12974.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 12974.AA | CDPK | 30-287 | 51 | 1.3e-188 | 583.3 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-271/271 Sequence Identity: 51% (140 aa) WSKKRTLGSGQFGSVVSCKLK-GTNDTR-AIKVIPKSRVRDPQ---QFLNEINIMKELDHPNVIRLYETFEDQRNVYLSME--LCSGGELFDVITAKKKF . .|..||.|.||.| .|.| .||..| |.|.||||||.|.. ||.|||.|.|.|||||.|..||...|..|.|. || .|.||||||.|..|..| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF SEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESLD----NIKVADFGLSCIFVDKQQK--KQDILGKTGSSYYMAPEVLQGIYNELCDVWSL .| ||.....||.|||.||| |||.||||||||.|...|.. . |||| |.|.|..| . || .... . | ||.||||||. ||| ||.||. TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQN-QKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSC GVILYILLSGIPPFFGSNDSKIFEKIEKGTYSFDFPQFQNVSENAKDLIRKCLVP-QDQRLKANEILKHPWC ||||||||.| |||.| ||..|.||..|| |||. |.....|..|||||||.|.. ...|..|...|.|||. GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 12974.AA | CAMK | 35-287 | 30 | 1.2e-125 | 407.07 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 35-287
Range on HMM: 1-425/425
Sequence Identity: 30% (130 aa)
TLGSGQFGSVVSCKLKGTN-DTR-----------AIKVIPKSRVR----------------------------DPQQFLNEINIMKE-------LDHPNV
|||.|.|| | |. | |. ..| |||.|.|.... | .....||.||| |||||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IRLYETFED-------------------QRNVYLSM---ELCSGGEL----FDVITAK---------------KKFSEEEARLVFNQIVSAVSYCHANNI
|.|||..|| ....|. | |.|||||| || |... ..|.|.||| .| ||.||| ||| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
CHRDLKPENFLLLQKESLD--------------NIKVADFGLSCIFVDKQQKK--------------------QDILGKTGSSYYMA-PEVLQGI-----
.|||||||| || .... . |||..|||....| .... . | |. .||| ||||.|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YNELCDVWSLGVILYILLSGIPPFFGS-------------NDSKIFEKIEKGTYSFDFPQFQN------------VSEN--------AKD
|.. ||.||.||||||.|.| ||| |. ||...|||| || |.|. |.| . .|.. .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LIRKCLVP-QDQRLKANEILKHPWC
||||.|.. ..|... ..|.|||
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 12974.AA | CAMK1 | 33-287 | 41 | 2e-118 | 345.9 | In-house | 4-276 (276) | Show / Hide |
Range on Protein: 33-287 Range on HMM: 4-276/276 Sequence Identity: 41% (115 aa) KRTLGSGQFGSVVSCKLKGT---NDTRAIKVIP-KSRVRDP-----QQFLNEINIMK---ELDHPNVIRLYETFEDQRNVYLSMELCSGGELFDVITAKK . ..|.| |. |. |. | | .. |||.| |. . ....|||.||| ..||||.| .|| .|. . .|| |||..|||||| | |. GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEKG KFSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESLDNIK--VADFGLSCIFVDKQQKKQDILGKT-GSSYYMAPEVLQGI----YNELCDV ...|..||.. ||.||| |.|...|.|||||||| |. |. || .|||||| || .. .. . |. .|.||||| .. | ||. NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN----LMKTACGTPGYVAPEVLECKKDKPYDKACDM WSLGVILYILLSGIPPFFGSN-DSKIFEKIEKGTYSFDFPQFQNVSEN-AKDLIRKCLVPQ-DQRLKANEILKHPWC || |||.|||| | |||...| |...|||| |. | |. |.. |.|. |||.|.. |.. .|. . ..|.||| WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 12974.AA | Ciliate-E2a | 30-287 | 39 | 7.6e-111 | 327.5 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-275/275 Sequence Identity: 39% (109 aa) WSKKRTLGSGQFGSVVSCKLKGTNDT-RAIKVIPKSRVRD--PQQFLNEINIMKELDHPNVIRLYETFEDQRNVYLSMELCSGGELFDVITAKKKFSEE- .... .|.|.||||. ..|.|.. ...|.| | .. . ..| ||||||..|||||.|.|||..|| .| || ||.|.||||.| | .|.| || YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI -EARLVFNQIVS-AVSYCHANNICHRDLKPENFLLL--QKES--LDNIKVADFGLSCIFVDKQQKKQD--ILGKTGSSYYMA------PEVLQGI-YNEL |.. . |. . ...|.| .|| ||||||||.|. |.| . .||..||||. ....|.. . | |. .|.| .|||.. | . QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLA----TFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTK CDVWSLGVILYILLSGIPPFFGSNDSKIFEKIEKGTYSFDFPQ-FQNVSENAKDLIRKCLVPQ-DQRLKANEILKHPWC ||.||.|||.||||.| ||| | . . |.....| ..|. |. ....| ..|||..| |... .|..|...|.||| CDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 12974.AA | AGC | 30-287 | 24 | 2.3e-108 | 280.75 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-395/395 Sequence Identity: 24% (99 aa) WSKKRTLGSGQFGSVVSCKLK------GTNDTRAIKVIPKSR--------VRDPQQ----------FLNEINIMKELD----------HPNVIR-LYETF ....| | || | .. | .|.. |.||. |.. . . . .| ||..... ||.... |. .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF EDQRN--VYLSMELCS---------GG-ELFDVIT---AKKKFSEEEARLVFNQ-------IVSAVSYCHA-NNICHRD-LKPENFLLLQKESLDNIKVA .|... .|. ||... || ||| . ...|.||.|| . . ||.|. | | ..| ||| ||||| || .. .|| . QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKLT DFGLSCIFVD-----------------------------------KQQKK----------QDILGKT--G--SSYYMAPEVLQGIYNELCDVWS--LGVI ||||...... .|... .. . .| | . |||||.| |. || || ||.. DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---YGKACDWWSFGLGCL LYILLSGIPPFFGSNDS----------KIFEKIEKGTYSFDFPQF------------QNVSENAKDLIRKCLV-PQDQRLK----------ANEILKHPW .| .|.|.|||.| |. ..|.||..| | . ... ...|..|||||.|.|. ..|| |.|| .||| MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW C F |
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| Kinase | 12974.AA | S_TKc | 30-287 | 37 | 1.1e-102 | 348.36 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-231/231 Sequence Identity: 37% (102 aa) WSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPKSRVRDPQQFLNEINIMKELDHPNVIRLYETFEDQRNVYLSMELCSG--GELFDVITAKKK------ . . |..|.| ||.| |. |.|. |||.|. .....||.|.|. .|||...||..|.| ..|. ||.|.| |.|||.| ... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP FSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESLDNIKVADFGLSCIFVDKQQKKQDILGKTGSSYYMAPEVLQGIYNE-LCDVWSLGVIL |.| .|| .. ||..|. ||| ..|.|||||||| || . .||..||||.... |. .||||||| |. ||.||.|.|| FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCIL YILLSGIPPFFGSNDSKIFEKIEKGTYSFDFPQFQNVSENAKDLIRKCLV-PQDQRLKANEILK-------HPWC |..|.| ||| .. ..|.|| |. |||.|||||. ..|. | |.|. ||| YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 12974.AA | CAMKL | 30-287 | 36 | 1.8e-95 | 305.16 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-297/297 Sequence Identity: 36% (111 aa) WSKKRTLGSGQFGSVVSCKL-KGTNDTRAIKVIPKSRVR-DPQQFLN--------------EINIMKELD---HPNVIRLYETFEDQRN------VYLSM . .||| | || | .. . |. |||.| |.. . ||. | ||.||| |. |||.|.|||..|.... .|| | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELCSGGE--LFDVITAK----KKFSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESLDNIKVADFGLSCIFVD-----KQQKKQDILGKTG |.||||| ||| | .. ....|.||| | ||||||.||| ..|.|||.|||| || .. . |||..|||.| .. . | | | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFC----G SSYYMAPEVLQG--I-YN-ELCDVWSLGVILYILLSGIPPFFGSN-------DSKIFEKIEKGTYSFDFPQFQNVSENAKDLIRKCLVP-QDQRLKANEI | |||||..|| |. |.||.||||| .. | || . . . ........ . .| . || ..||||| |.. ..| .. .| SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI LKHPWC ..|||. MNHPWM |
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| Kinase | 12974.AA | Pkinase | 30-287 | 35 | 1.6e-93 | 321.82 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-293/293 Sequence Identity: 35% (105 aa) WSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPKSRVRD--PQQFLN--EINIMKELDHPNVIRLYETFEDQRNVYLSMELCSGG----ELFDVIT--AK . ..|..||| ||.| |. |||... |.|.|.|.. .. .|. .. || |||.|.|||..|||..||| ...|. ||.| || .|||.|. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KKF--SEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESL-DNIKVADFGLSCIF-VDKQQKKQDILGKTGSSYYMAPEVLQ--GIYNELCDV ..| ||.|.. .. ||.... |||...|.||||||||.|. .. . . .|..||||.. | ... ... .|...||||||.. | .|. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF---CGTPWYMAPEVIRGGQYYGPKVDM WSLGVILYILLSGIPPFFGS------NDSKIFEKIEKGTYSFDFPQFQNVS-----------------ENAKDLIRKCLVP-QDQRLKANEILKHPWC ||.|.|||..|.| ||| |. .. .....| .. ..||.|. ..| |..||.|..|| . .|. | .||.||| WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 12974.AA | CAMK-Unique | 30-287 | 27 | 1e-90 | 299.67 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 30-287
Range on HMM: 1-363/363
Sequence Identity: 27% (102 aa)
WSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPK----SRVRDPQ----------------QFLNEINIMKELDHPNVIRLYET----FEDQR-------
. . | .|.| || | |. . | . .|.|.. | . ....| .. .|..|.| .|||| |.||.. |.| .
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------NVYLSMELCSGGELFDVITA--------------------KKKFSE--EEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQK-------
. |. ||.| ||.|||.| . . .||| ...... ...|||.| | ..| |||||.|| ..
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
------ESLDNIKVADFGLSCIFVDKQQKKQD-ILGKT-GSSYYMAP--------------EVLQ-GIYNELC----DVWSLGVILYILLSGIPPFFGSN
.| .||..||||.| .....| . .. .. |...|||| ||. | . | | ||||||.|..|.|.||| ...
RDFPYDWSNWHIKLCDFGLCC---HYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCEC
DS--------KIFEKIEKGTY-SFDFPQFQN---VSENAKDLIRKCLVPQ-DQRLKANEILKHPWC
. .|||.| || | .|| .... .|..|||.. .|.. |.|..|.|.|.|.|
EDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 12974.AA | Ciliate-E2 | 30-287 | 26 | 3.8e-88 | 299.15 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-365/365 Sequence Identity: 26% (103 aa) WSKKRTLGSGQFGSVVSCKLKGTNDTR------------------AIKVIPKSRV--RDPQQFLNEINIMK----------------ELDHPNVIRLYET . . .|.|.|||| || . .. .|| . . .. .. .|...||.||. .|.|||.|..||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FE--DQRNVYLSMELCSGGELFDVIT------------AKKKFSEEEARLVFNQIVS---------------AVSYCHANN-ICHRDLKPENFLLLQKES |. |. |.|| ||.|.||.||| | . |.|.|.|.. .. ||.. |. |.| .| |.|||.|||| |. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- LDNIKVADFGLSCIFVDKQQKKQDILGKTG-----------------------------SSYYMAPEVLQGI----------YNELCDVWSLGVILYILL ||..||||| .. |..|.... . . . .|||||.|.| |.. ||.||||||||..| ---IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML SGIPPFFGSNDSKIFEKIEKGTYSFDFP--------------QFQNVSENAKDLIRK----CLVPQ-DQRLK-ANEILKHPWC .| ||| ...|... ..|..| ....|...||||.| .|. . ..|. ...||.||| FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 12974.AA | RAD53 | 30-287 | 35 | 1.5e-86 | 257.71 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 30-287 Range on HMM: 1-305/305 Sequence Identity: 35% (110 aa) WSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPK-------SRV-RDPQQFLNEINIMKELDHPNVIRLYETFED-QRNVYLSMELCSGGELFDVITAKK . ..|||| ||.| .. | | . ||| | | ... .. |. ||..|.| | ||..||.|. |.. |...|. .|| .|||||. | . | YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK K----FSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLL-QKESL--------------DNIKVADFGLSCIFVDKQQKKQDILGKT--GSSYYMA . |.| .... | |.. ||.| | |.|||||||||| |. |.| . ||..||||| . .... . || |. | | RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGS------FMKTMCGTPQYVA PEVLQ----------------GIYNELCDVWSLGVILYILLSGIPPFF-GSND----SKIFEKIEK-GTYSFDFPQFQNVSENAKDLIRKCL-VPQDQRL |||. . |. .|.||.|.||||.|.| ||| .. . ..||.| . | |.|. |. .||.|||||.. | | . |. PEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRY KANEILKHPWC ..|.| ||| TIDEALNHPWM |
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| Kinase | 12974.AA | RSK | 33-287 | 36 | 8.2e-83 | 281.43 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 33-287 Range on HMM: 1-278/278 Sequence Identity: 36% (103 aa) KRTLGSGQFGSVVSCKLK---GTNDTRAIKVIPKSRVRDPQQ----FLNEINIMKELD-HPNVIRLYETFEDQRNVYLSMELCSGGELFDVITAKKK--- . || | .|.| |. . |. | ||. |. .. | . |.||... ||....|...|... .|| ||.|.|||||. . .| LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESL-DNIKVADFGLSCIF-VDKQQKKQDILGKTGSSYYMAPEVLQ----GI-YNELCDVW |||.||. .. .||.||.. | | |||||||| |. ... ||. |||....| |. |. . .. |||||.| . ... ||.| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFC---YTIEYMAPEMLKRANQQGGHDKACDWW SLGVILYILLSGIPPFFG---SNDSKIFEKIEKGTYSFDFPQFQNVSENAKDLIRKCL-VPQDQRLK-----ANEILKHPWC ||||..| .|.| ||| | .| ..|...|.||..|...| |..|..|||||||.| . .||. |.||..||| SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 12974.AA | TyrKc | 30-285 | 24 | 2.7e-21 | 78.0 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 30-285 Range on HMM: 1-280/280 Sequence Identity: 24% (71 aa) WSKKRTLGSGQFGSVVSCKLKGTNDTRAIKVIPKSRVRDPQQFLNEINIMKEL--DHPNVIRLYETFEDQ-------RNVYLSMELCSGGELFDVITAKK .....||.|.|| |. ...| . |.|.. .. . |..|..||..| .|||..||| .| ... ||....| | | . ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR K-FSEEEARLVFNQIVSAVSYCHANNICHRDLKPENFLLLQKESLDNIKVADFGLSCIFVDK-------QQKKQD--ILGKT-GSSYYMAPEVL-QGIYN . .. .. || . .| | .|. |||| | |. . .|..||||| |. . ... ||| ||||.. |... PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT ELCDVWSLGVILY-ILLSGIPPFFG-----SNDSKIFEKIEKGTYSFDFPQFQN--------VSENAKDLIRKCLVP-QDQRLKANEILKHP . |||| || .. |. | .| | ... ..|....| . || .| .. .....| ..| .|| . TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRM---PQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 12974.AA | Pkinase_Tyr | 30-112 | 29 | 8.1e-16 | 54.2 | Pfam | 1-94 (270) | Show / Hide |
Range on Protein: 30-112 Range on HMM: 1-94/270 Sequence Identity: 29% (28 aa) WSKKRTLGSGQFGSVVSCKLK----GTNDTRAIKVIPKSRVRDP----QQFLNEINIMKEL-DHPNVIRLYETFE-DQRN--VYLSMELCSGGEL .. ..||.|.||.|. ...| .|. . |.|.. | .. . |..|..|||.| .|||..||| ... .|. ||.. .| | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL |
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| Kinase | 12974.AA | Pkinase_Tyr | 198-245 | 34 | 0.029624 | 8.26 | Pfam | 181-232 (270) | Show / Hide |
Range on Protein: 198-245 Range on HMM: 181-232/270 Sequence Identity: 34% (18 aa) MAPE-VLQGIYNELCDVWSLGVILYILLS-GIPP-FFGSNDSKIFEKI-EKG |||| |.... |||| || .. ... | | . | .. ..|.| |.| MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG |
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| Efhand | 12974.AA | efhand | 332-360 | 44 | 2e-06 | 27.73 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 332-360 Range on HMM: 1-29/29 Sequence Identity: 44% (13 aa) DLGKQFKQLDKNGDGVLSIEEITEGMKNF .| . ||..||.||| ...|| |.||.. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 12974.AA | EFh | 332-360 | 34 | 0.000236 | 21.71 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 332-360 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) DLGKQFKQLDKNGDGVLSIEEITEGMKNF .. . |. .||.||| .. || ..||.. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 12974.AA | EFh | 366-394 | 24 | 4.3e-07 | 30.81 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 366-394 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) QLLEIIKEIDTDKNGQIEYSEFIAASMDK .. |.....|.|..|.|.. ||... . . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 12974.AA | efhand | 366-394 | 34 | 1e-06 | 28.49 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 366-394 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) QLLEIIKEIDTDKNGQIEYSEFIAASMDK .| |..||.|.|..|.|.. ||... ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | 12974.AA | efhand | 402-430 | 31 | 2e-06 | 27.69 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 402-430 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KLYQAFKALDIDGSGSISKDELKQVLDSD .| ..|| .| ||.| |...|..... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 12974.AA | EFh | 402-430 | 31 | 1e-05 | 26.23 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 402-430 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KLYQAFKALDIDGSGSISKDELKQVLDSD .. ..|. .| ||.| |...|.|... | EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 12974.AA | EFh | 440-468 | 44 | 4.3e-08 | 34.12 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 440-468 Range on HMM: 1-29/29 Sequence Identity: 44% (13 aa) YWKSVIQEADKDGNGEIDYEEFVEMMVPS .| .....||||.|.||.|||..|| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 12974.AA | efhand | 440-468 | 51 | 1.2e-07 | 32.42 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 440-468 Range on HMM: 1-29/29 Sequence Identity: 51% (15 aa) YWKSVIQEADKDGNGEIDYEEFVEMMVPS .| ...|.||||.|.||.|||.||| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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