Gene 11744 (Tetrahymena)
11744
Sequence
Protein domains of 11744.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 11744.AA | CDPK | 396-645 | 45 | 9.60000000001e-164 | 505.89 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 396-645 Range on HMM: 1-271/271 Sequence Identity: 45% (123 aa) LIM---LGRGGFGQVFLVKQKQGNKEER-AMKVIMKS-----VQ-ES-IREVMILKKFSHPNVLKIYEYFEDDQNIYVITE--RCYGYNLFDYIILRGKF .. ||.|.||||..||.||....|| |||.|.|| | .. ..|..|||.. |||..||||...|..|.|...| |.|..|||||| .|.| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF VEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQ--KFVVKLIDWGLAEEIKG------DYLSKRCGTLHYLAPEVLNKRYNEKVDLWSLG |.|...| . .|.|.. .|..||||||.|||||..|...... .. .|.||||.... .. ...|.|||| .|.|||||.|.||||.|.||.| TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG MVLYTLIQGSPPICGKSQMDILEQVQEFRCDFKYRCWIDISDEAKDLILKLLERDFNKRISAAEALKHPWF ..||.|..|.||..||....|.|.|......|....| .||||||||| |.|..|..||.||..||.|||| VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 11744.AA | Ciliate-E2a | 394-645 | 38 | 1.2e-105 | 311.96 | In-house | 2-275 (275) | Show / Hide |
Range on Protein: 394-645 Range on HMM: 2-275/275 Sequence Identity: 38% (105 aa) KRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMKSVQES------IREVMILKKFSHPNVLKIYEYFEDDQNIYVITERCYGYNLFDYIILRGKFVEQ-- | . ..| | ||.|.|...|| .|.....|.| | |. ..|..|... .|||..|.||..||..|.| ..| |.| |.|.|. ..| | KFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQ ETCKIADGVL-RALAEAHKQNIVHRDVKPENIMLD-FDETR-QKFVVKLIDWGLAEEI--K-GDYLSKRCGTLHYLA------PEV-LNKRYNEKVDLWS | |.| | .|. |..||.||| |||||... . . |.. .|.||.|||. | . ..|. ..||| .|.| .|| ..|.| .|.|.|| EICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMWS LGMVLYTLIQGSPPICGKSQMDILEQVQEFRCDFKYRC-WIDISDEAKDLILKLLERDFNKRISAAEALKHPWF .| ..|.|. |.|| ||. .||.|. . || . | ..|.|.|||. |.|| | .|||.|..||.|||| CGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 11744.AA | CAMK | 398-645 | 24 | 1.3e-98 | 318.43 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 398-645
Range on HMM: 1-425/425
Sequence Identity: 24% (105 aa)
MLGRGGFGQVFLVKQKQGNK-----------EERAMKVIMKS--------------------------------VQESIREVMILKK-------FSHPNV
||||.||.|.|...|. .. .. |.|.| |. .. ||. |.|| .|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
LKIYEYFED-------------------DQNIYVIT---ERCYGY----NLFDYIILR---------------GKFVEQETCKIADGVLRALAEAHKQNI
.|.||..|| |...| .. | | | |||||. . |.| |.|.... .. |.. |..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDVKPENIMLDFDETRQK------------FVVKLIDWGLAEEIK-------------------------GDYLSKRCGTLHYLA-PEVLNKR-----
|||| |||||.|| ... . . .|.||.|.| ... |. .. .|||..| | |||||.
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YNEKVDLWSLGMVLYTLIQGSPPICGK-------------SQMDILEQVQEFRCDFK-----------YRCWID-ISDE--------AKD
|..|.| ||.| .||.. | || |. .. ...|.... ..|| . .| | |||| .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LILKLLERDFNKRISAAEALKHPWF
|| |.|..| .||......|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 11744.AA | Ciliate-E2 | 393-645 | 27 | 6.3e-86 | 291.78 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 393-645
Range on HMM: 1-365/365
Sequence Identity: 27% (104 aa)
GKRLIMLGRGGFGQVFLVKQ-KQGNKE---------------------ERAMKVIMKSVQESIRE---VM--------------ILKKFSHPNVLKIYEY
| . ..|.|.||.|...|. |..... . |||...|. |.| .| ||.. .|||..|.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
FE--DDQNIYVITERCYGYNLFDYIILR-----------GKFVEQETCKIADGVLR---------------ALAEAHKQN-IVHRDVKPENIMLDFDETR
|. ||.||| ..| | | .|||||. . ..|.|.| ..| .|. || . |..| |.||| |||||..
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------
QKFVVKLIDWGLAEEIK------------GDYLSKR----------------------CGTLHYLAPEVLN----------KRYNEKVDLWSLGMVLYTL
.|.||.||. ... . |. . |||..|.|||.|| |.|..|.|.||||..|| .
----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
IQGSPPICGKSQMDILEQVQEFRCDFKYRC--------------WIDISDEAKDLILK----LLERDFNKRIS-AAEALKHPWF
. | || ..| .. .|| . | ..|.|.|||| | .|..| .|||. . ..|.||||
LFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 11744.AA | S_TKc | 393-645 | 34 | 9.3e-85 | 288.8 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 393-645 Range on HMM: 1-231/231 Sequence Identity: 34% (94 aa) GKRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMKSVQESIREVMILKKFSHPNVLKIYEYFEDDQNIYVITERCYG--YNLFDYIILRGK------FVE . | .|.|.||.|.... | ... |.|.| . .||. |||| |||. |.|..|.| ...|...| | | .||||| ||. | | YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE QETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEEIKGDYLSKRCGTLHYLAPEVLNKRYNE-KVDLWSLGMVLYTLIQG ...... ...||. |...|.|||.|||||.|| ..|..| ||| .. . |||..|.||||| |. |.| ||.| .|| .. | -HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCG SPPICGKSQMDILEQVQEFRCDFKYRCWIDISDEAKDLILKLLERDFNKRISAAEALK-------HPWF || . .. ..... |.||||.| |.|..| .||..| |||. |||| YPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 11744.AA | CAMK1 | 398-645 | 32 | 1.6e-80 | 233.78 | In-house | 6-276 (276) | Show / Hide |
Range on Protein: 398-645 Range on HMM: 6-276/276 Sequence Identity: 32% (90 aa) MLGRGGFGQVFLVKQKQG--NKEERAMKVIM-KSVQES---------IREVMILKKF---SHPNVLKIYEYFEDDQNIYVITERCYGYNLFDYIILRGKF ..||| |..|.|...|. |... |.|.| |.. . .|. |.||. .|||. |.||..|.| .| ..| . | ||| |. .|.. EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIVEKGNY VEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETR-QKFVVK--LIDWGLAEEIKGD--YLSKRCGTLHYLAPEVLN----KRYNEKVDLWSL |.. ..| .| |. |...||||| ||||. . .. . .| ..| ||. ...| .....|||. | |||||. | | ..|.|| TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLY---YDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSI GMVLYTLIQGSPPICGKS-QMDILEQVQEFRCDFKYRCWIDISDE-AKDLILKLLERDFNKRISAAEALKHPWF | ..|.| | || ... .. ..|.. . .| | .|||. |||.| ..|| | .||......|.|||. GVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 11744.AA | AGC | 394-645 | 23 | 2.7e-78 | 201.18 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 394-645 Range on HMM: 1-395/395 Sequence Identity: 23% (93 aa) KRLI-MLGRGGFGQVFLVKQKQ-----GNKEERAMKVIMKSV----------QESIRE------------VMILKKFS----------HPNVLK-IYEYF ... ..|.|.||.|.||. | .... ||||. |.. . ..| ||.| . ||.. | . | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF EDDQN--IYVITERCY---------GY-NLFDYII---LRGKFVEQETCKIAD-------GVLRALAEAHK-QNIVHRD-VKPENIMLDFDETRQKFVVK .|... .| . | . | || .. .|.| |.... .| .. || |. ..|.||| .|||||.|| | .| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED-----GHIK LIDWGLAEEIKGDY----------------------------------------------------LSKRCG--TLHYLAPEVLNKRYNEKVDLWS--LG | | ||. |...|. . || | .|.|||.| |. .| || || LTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---YGKACDWWSFGLG MVLYTLIQGSPPICGKS----------QMDILEQVQEFRCDFKYRCWID------------ISDEAKDLILKLLERDFNKRIS----------AAEALKH ..| .. | || .|.. .|.. ..... |. .. . .. .|.|||||| |||..| .||. | | .| CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH PWF ||| PWF |
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| Kinase | 11744.AA | Pkinase | 393-645 | 32 | 1.4e-74 | 258.91 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 393-645 Range on HMM: 1-293/293 Sequence Identity: 32% (97 aa) GKRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMKSVQESIR--------EVMILKKFSHPNVLKIYEYFEDDQNIYVITERCYGY----NLFDYII--L ... .|.|.||.|.. . | .| . |.|.| |. ..| |. |.|...|||....|..|||...||...| | | ||||| YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR RGKF--VEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAE---EIKGDYLSKRCGTLHYLAPEVLN--KRYNEKVDLW .|.| |.| .... .||.|. |...|.|||.|||||..| .. . ||..|.|||. . .. .. .|||..|.||||.. . | ||| | HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SLGMVLYTLIQGSPPICGK------SQMDILEQVQEFRCDFKYRCWIDIS-----------------DEAKDLILKLLERDFNKRISAAEALKHPWF |.| .|| .. | || .|. .|| ..... . . .| . |..|| .|.||.| ..|..| .||..|...|.|||| SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 11744.AA | CAMKL | 399-645 | 28 | 1.6e-74 | 237.21 | In-house | 7-297 (297) | Show / Hide |
Range on Protein: 399-645 Range on HMM: 7-297/297 Sequence Identity: 28% (85 aa) LGRGGFGQVFLVKQKQGNKEERAMKVIMKSVQESI-------------------REVMILKKFS---HPNVLKIYEYFEDDQN------IYVITERCYGY ||.|.||.| | . .. ..|. |.|.| |. . ||. |.|... |||. |.|| .|.... || ..| | | LGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGG N--LFDYIILR----GKFVEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEEIK------GDYLSKRCGTLHYLAPE . |||||. . |.. | |.... .. |.. |...||||| |||||.|| . . ..|.|| |.. ... |. |. .||...| ||| EMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPE VLNK--R-YN-EKVDLWSLGMVLYTLIQGSPPICGKS------QMDILEQVQEFRCDFKYRCWIDISDEAKDLILKLLERDFNKRISAAEALKHPWF .... . |. ||| ||.| .||... | | . . .. .. .. .... |...| ...||| |.|... .||... . ..|||. IFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 11744.AA | CAMK-Unique | 393-645 | 25 | 1.8e-72 | 238.51 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 393-645
Range on HMM: 1-363/363
Sequence Identity: 25% (92 aa)
GKRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMK-----SVQES-------------------IREVMILKKFSHPNVLKIYEY----FEDDQ------
| . .| |.|| |. .. . .. ..|.|.. | ..| ||. |.|. .||| .|.|.. |.|..
YKMHRIIGHGNFGHVYECMDRE-TGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL
---------NIYVITERCYGYNLFDYIIL--------------------RGKFVE--QETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDET----
..| ..|.| | |||.|. .|.| | .|| | .| |.| .|.|.||||| |.||||. .
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH
-------RQKFVVKLIDWGLAEEIKGDYLS----KRCGTLHYLAP--------------EVLN-KRYNEKV----DLWSLGMVLYTLIQGSPPICGKSQM
.||.|.||. .. . . ..|||. |.|| ||.| .| ... |.|||| ..|... |.|| . .
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED
--------DILEQVQEFRC-DFKYRCWID---ISDEAKDLILKLLERDFNKRISAAEALKHPWF
|.| . .|. . | . ||.||||.. .....| ..|.||.|.|.|.|.
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 11744.AA | Ciliate-E2-Unclassified | 399-645 | 25 | 4.9e-71 | 242.3 | In-house | 7-352 (352) | Show / Hide |
Range on Protein: 399-645
Range on HMM: 7-352/352
Sequence Identity: 25% (89 aa)
LGRGGFGQVFLVKQKQGN----------KEERAMKVIMKSVQESIREVMILKKFS-------------------HPNVLKIYEYFEDDQNIYVITERCYG
.|.||||.|.....|. . . ....| ||.. | ..| .... . ||...| ...|.|.|||| ..| | |
IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEG
YNLFDYIILRGK-----------------FVEQETC-----KIADGVLRALAEAHKQN-IVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEEIK-----
.|..|| |.| | ||... ... .| .| |..| |.||| |||||..| . .. .|.||.|.. ...
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNC
------------GDYLSKRCGTLHYL----APEVLNK-RYN----EKVDLWSLGMVLYTLIQGSPPICGKSQMD----------------ILEQVQEFRC
. .. .|||. |. ||||| . |. .|.| ||||..|| .. | .| .... . .... .. .
DTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNI
DFKYRCW----IDISDEAKDLIL----KLLERDFNKRISAAEALKHPWF
.|. | ..|.||||.| |.|. . ||||.. ..|.||||
QFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 11744.AA | RSK | 396-645 | 31 | 3.9e-67 | 229.35 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 396-645 Range on HMM: 1-278/278 Sequence Identity: 31% (89 aa) LIMLGRGGFGQVFLVKQKQGNKEER--AMKVIMKSVQESI--------REVMILKKFS-HPNVLKIYEYFEDDQNIYVITERCYGYNLFDYIILRGK--- | .||.||.| |||.. ... . .. ||||. |.. .|. ||. ||.. . .. |.... .| |.| | | ||. . .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FVEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEE--IK-GDYLSKRCGTLHYLAPEVLN----KR-YNEKVDLWSL | | | | .. . |. |.| |.||| |||||..| ||. . .||.| |.. . .. . . . |.|..|.|||.|. .. ... .|.||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYD-DES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL GMVLYTLIQGSPPICG---KSQMDILEQVQEFRCDFKYRCWIDISDEAKDLILKLLERDFNKRIS-----AAEALKHPWF | ..|.. | || | ... .|....|. . ... | .|.|||||| |.|.|| .||.. |.| ..|||| GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 11744.AA | TyrKc | 393-649 | 20 | 1.7e-13 | -4.58 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 393-649 Range on HMM: 1-280/280 Sequence Identity: 20% (62 aa) GKRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMKSVQES-----IREVMILKKF--SHPNVLKIYEYFEDD-------QNIYVITERCYGYNLFDYI-I . . .||.| ||.|.. . | ..| |...|. .|| |..|. .|||....| . .. . .....| . . .| ||. ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK LRGKFVEQETCKIADGVLRALAEAHKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEEIKGD--------YLSKR---CGT----LHYLAPEVLNK |.|. .. .... . . . |..|..||| |.... . .|| | ||. .|. | | .|. .| . .|||..|. HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY R-YNEKVDLWSLGMVLY-TLIQGSPPICG-----KSQMDILEQVQEF-RCDFKYR-CWID-----ISDEAKDLILKLLERDFNKRISAAEALKHPWFHKF . ...| | || | ... . | .| | .| ...|.|.. | . . .|| ..... ..| ..| . .| |.. GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HEC L . F |
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| Kinase | 11744.AA | Pkinase_Tyr | 394-465 | 24 | 6e-05 | 17.39 | Pfam | 2-87 (270) | Show / Hide |
Range on Protein: 394-465 Range on HMM: 2-87/270 Sequence Identity: 24% (21 aa) KRLIMLGRGGFGQVFLVKQKQGNKEERAMKVIMKSV-----QES------IREVMILKKF-SHPNVLKIYEYFE-DDQN--IYVITE . . .||.| ||.|.. . | ... ..| |.. .| .||. |.|.. .|||... | ... ||...| TFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVME |
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| Kinase | 11744.AA | Pkinase_Tyr | 502-601 | 28 | 0.851631 | 3.32 | Pfam | 128-231 (270) | Show / Hide |
Range on Protein: 502-601 Range on HMM: 128-231/270 Sequence Identity: 28% (31 aa) HKQNIVHRDVKPENIMLDFDETRQKFVVKLIDWGLAEEI-KGDYL-SKRCGTL---HYLAPE-VLNKRYNEKVDLWSLGMVLYTLIQ-GSPP-ICGKSQM . .|..|||. |.... ..||| | ||| | . || || |. .||| ......| | || | ... .. | | | | ESKNCIHRDLAARNCLVT-----ENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNE DILEQV-QE ...|.. .. EVYEYIYED |
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| Efhand | 11744.AA | efhand | 695-723 | 31 | 8.5e-07 | 29.3 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 695-723 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KYIEMFQALDTDKNGELSIEELKAGFSKI . |||. .|.|..|....||......|. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 11744.AA | EFh | 695-723 | 31 | 6e-06 | 27.04 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 695-723 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KYIEMFQALDTDKNGELSIEELKAGFSKI . |||. .|.|..|... ||.|...... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 11744.AA | EFh | 774-802 | 31 | 3e-06 | 27.88 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 774-802 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) QLLEAFQVFDKDRNGKISLNEIIQTLGIQ .. |.|..||||..|.|...| .. . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 11744.AA | efhand | 774-802 | 34 | 6e-06 | 26.07 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 774-802 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) QLLEAFQVFDKDRNGKISLNEIIQTLGIQ .| |.|..||||..|.|...| .. . . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 11744.AA | EFh | 810-838 | 41 | 4e-07 | 30.9 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 810-838 Range on HMM: 1-29/29 Sequence Identity: 41% (12 aa) CFKKIIEQSDNNQDGEIDFEEFRQIMTNF ||.... | . ||.||||||...|... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 11744.AA | efhand | 810-838 | 37 | 1e-06 | 28.46 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 810-838 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) CFKKIIEQSDNNQDGEIDFEEFRQIMTNF .|..... | ..||.||||||...|... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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