Gene 10025 (Tetrahymena)
10025
Sequence
Protein domains of 10025.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 10025.AA | CDPK | 89-345 | 52 | 1.3e-190 | 589.6 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-271/271 Sequence Identity: 52% (143 aa) YTMGKFLGQGGFGTVCVGIQK-VTNVKR-AIKMVSKVTLSEKDK-QILLQELALLKSIDHPNILKILEHYEDDQHHFFVTE--LLSGGELFTKIMELNGF |...| ||.|.||.|. ...| ||..| |.|...| ...|.. |....|...||..|||||.|| |.|.|......|.| ...||||| .|.| . | YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF NEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSD-----QIKVIDFGCSTKFDKA-----KKIKDIAGTVLYLAPEVIKKNLYDEKCDIWSL .| .|...||||||||.|||..||||||||||||||.|||.| .|||||.|.|.|||.. ||.....||..|.||||..|. |.|||||||. TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVVLYIMLCGYPPFDGKNDEEVFNSIQNKQVQFEGKEWEKISVQAKDLIEKMLQKDPNLRISAQQAYQHPWI ||.|||.||||||| ||||.|....... . .|||.||..||..|||||.|||..||. |.|||||.||||. GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 10025.AA | CAMK1 | 89-345 | 43 | 3.6e-134 | 392.43 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-276/276 Sequence Identity: 43% (121 aa) YTMGKFLGQGGFGTVCVGIQKVT---NVKRAIKMVS-KVTLSEKDK---QILLQELALLKS---IDHPNILKILEHYEDDQHHFFVTELLSGGELFTKIM | || .| | |..| ...| | . . |||. . | ...|| . |..|.. .|. |||||| |. |.||.| | .|.||..||||| .|. YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV ELNGFNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSD-QIK--VIDFGCSTKFDKAK-KIKDIAGTVLYLAPEVIKK---NLYDEKCDIW | ..| .|. |.|||||| |.|...||||||||||.|. .|. | .|| ..||| |..|| . |. || | ||||.. || .||.| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SLGVVLYIMLCGYPPFDGKN-DEEVFNSIQNKQVQFEGKEWEKISVQ-AKDLIEKMLQKDPNLRISAQQAYQHPWI | ||..||.||||||| ..| |.| | | . .. | ..| .|| | |||.| .|| .||. |....|. .|||| SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 10025.AA | Ciliate-E2a | 89-345 | 42 | 2.9e-133 | 394.6 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-275/275 Sequence Identity: 42% (116 aa) YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSEKD--KQILLQELALLKSIDHPNILKILEHYEDDQHHFFVTELLSGGELFTKIMELNGFNEA | | .|.| || | . .| |. ..|.| ..| ..... |. . .|.......|||||.|. | |||... ..|.|...||||. || . |.| YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --QASGYMRQILS-AVSYCHQQNIVHRDLKPENILFT--SKKS---DQIKVIDFGCSTKF--DKAKKIKDIAGTVLYLA------PEVIKKNLYDEKCDI ... .|.|.|. ...|.||.||.|||||||||||. ||.| .||.|||| .|.. |. |... . || |.| .||.|.. ||.|||. IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WSLGVVLYIMLCGYPPFDGKNDEEVFNSIQNKQVQFEGKE-WEKISVQAKDLIEKMLQKDPNLRISAQQAYQHPWI ||.||..||.|||.|||.||. .|.. .. . . .|...| |||.| ..|||. |||.|||. ||.||||..||| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 10025.AA | CAMK | 94-345 | 30 | 4.8e-126 | 408.39 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 94-345
Range on HMM: 1-425/425
Sequence Identity: 30% (130 aa)
FLGQGGFGTVCVGIQKVTN------------VKRAIKMVSKVTLS--------------------------EKDKQILLQELALLKS-------IDHPNI
||.|.||.| .|.| |. .| |||...| |. .||.. ...|....|. .|||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
LKILEHYED-------------------DQHHFFVT---ELLSGGEL----FTKIMELNG---------------FNEAQASGYMRQILSAVSYCHQQNI
.|..|.||| |.| ..|. |. ||||| | .| | . |.|..|. |.|||.||| |||..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENILFTSKKSD---------------QIKVIDFGCSTKFDKAK------------------------KIKDIAGTVLYLA-PEVIKKNL----
|||||||||||......| .||.|||| ..|||. . | |. || | | |||....
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YDEKCDIWSLGVVLYIMLCGYPPFDGK-------------NDEEVFNSIQNKQVQFEGKE------------WEKISVQ--------AKD
|..|||.||.||.|||||||||||.|. ||.| | |.. . .|. .. | .|| . .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LIEKMLQKDPNLRISAQQAYQHPWI
|| ||||.||. |....|. .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 10025.AA | S_TKc | 89-345 | 36 | 1.6e-107 | 364.39 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-231/231 Sequence Identity: 36% (99 aa) YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSEKDKQILLQELALLKSIDHPNILKILEHYEDDQHHFFVTELLSG--GELFTKIMELNG---- |.... .|.|.||.|. .. | |. . |||... . ...|...||. .|||| |......| .| ..|.|...| |.||. | . .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSDQIKVIDFGCSTKFDKAKKIKDIAGTVLYLAPEVIKKNLYDE-KCDIWSLGVVLYI |.| .| ||.||..|. |||...|.||||||||||... .||..||| .... . . || |.||||. |. |||.||.|..||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MLCGYPPFDGKNDEEVFNSIQNKQVQFEGKEWEKISVQAKDLIEKMLQKDPNLRISAQQAYQ-------HPWI ||||||||. .....|. | | .|||.|.|.|||||. |..| .| | |||. MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 10025.AA | CAMKL | 89-345 | 35 | 8.60000000001e-104 | 332.12 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-297/297 Sequence Identity: 35% (107 aa) YTMGKFLGQGGFGTVCVGIQ-KVTNVKRAIKMVSKVTLS--------------EKDKQILLQELALLKSID---HPNILKILEHYEDDQH------HFFV |..|| ||.|.||.| .. . |..| |||.. | .. |.|. . .| ...|... |||| |..|..|...| . | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV TELLSGGE--LFTKIMELNG----FNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSDQIKVIDFGCSTKFDK-----AKKIKDIAGTVLY .|. |||| || .| . . . | .| | |||.|||.|||...|||||.||||||...... .||.|||| |..... .| | |. | MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY LAPEVIKK--NLYD-EKCDIWSLGVVLYIMLCGYPPFDGKNDE----EVFNSIQNKQVQFEGK--EWEKISVQAKDLIEKMLQKDPNLRISAQQAYQHPW |||.... || | ||||.||.|| |.||| |||. ... . . .|. . .. | ..| ...||| ||||..|. |....| .||| MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW I M |
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| Kinase | 10025.AA | CAMK-Unique | 89-345 | 28 | 3.1e-101 | 334.96 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 89-345
Range on HMM: 1-363/363
Sequence Identity: 28% (105 aa)
YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSEKDKQI------------------LLQELALLKSIDHPNILKILEH----YEDDQ-------
|.|.. .|.|.|| | .. ..| .|.|.||| | | ..| . . | |....|. |||||.|... ..|..
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------HHFFVTELLSGGELFTKIME--------------------LNGFNE--AQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSK-------
. . |.|.. ||.|| .|.. |.| .... .|...||||.| |.|.|||||||.|||.. .
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
-------KSDQIKVIDFGCSTKFDKAKKIK---DIAGTVLYLAP--------------EVIKKNLYDEKC----DIWSLGVVLYIMLCGYPPFDGKNDE-
. ||..||| ..... |. . || .|.|| |||. ||..| |||||||..|.||||.||||. ...
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------EVFNSIQNKQV-QFEGKEWEK---ISVQAKDLIEKMLQKDPNLRISAQQAYQHPWI
| | .| .. |. | |. ||..|||.... .. ||. |.|| ....|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 10025.AA | Ciliate-E2 | 89-345 | 28 | 4.9e-100 | 338.64 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-365/365 Sequence Identity: 28% (107 aa) YTMGKFLGQGGFGTVCVGIQKVTNV------------------KRAIKMVSKVTLSEKDKQILLQELALLK----------------SIDHPNILKILEH | | .|||.||.|. . .. .. | .||.. . ...........||. ... ...||||.|. |. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YE--DDQHHFFVTELLSGGELFT-----KIMELNG------FNEAQASGYMRQILS---------------AVSYCHQQN-IVHRDLKPENILFTSKKSD .. ||.. ..|.|...||.|| |. ... |.| ... .|.|||. |. |.|..| |.|||.||||||| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ QIKVIDFGCSTKFDK----------AKKIKDIA-----------------------GTVLYLAPEVIK---------KNLYDEKCDIWSLGVVLYIMLCG ||.|||| |.|.|. .|.... || |.|||... .. ||.|||||||||.||.||.| -IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG YPPFDGKNDEEVFNSIQNKQVQFEGKE--------------WEKISVQAKDLIEK----MLQKDPNLRIS-AQQAYQHPWI .||| .. |......| .| |.|.| ..|||| | ||||||. ||. ..|. .|||. KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 10025.AA | Pkinase | 89-345 | 32 | 3.2e-97 | 334.09 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-293/293 Sequence Identity: 32% (98 aa) YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSEKDKQILLQ--ELALLKSIDHPNILKILEHYEDDQHHFFVTELLSGG----ELFTKIM--EL |. |. .|.|.||.|. .. | |. . |.| ..|.. ... .|... |....|...||||..... .||..| .|.|.. || .||. |. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH NGF--NEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSDQI----KVIDFGCSTK--FDKAKKIKDIAGTVLYLAPEVIK-KNLYDEKCDIW ..| | .. ||.|||... |||...|.||||||||||. . ..| |..|||.. . . ....|| |.|||||. . |. |.|.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SLGVVLYIMLCGYPPFDGK------NDEEVFNSIQNKQVQFEGKEWEKIS-----------------VQAKDLIEKMLQKDPNLRISAQQAYQHPWI |.|..||.||||.|||.|. .. .... | ... |. .| || .||.|...|.|||. |..|.|. ||||. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 10025.AA | RAD53 | 89-345 | 35 | 3.2e-93 | 278.0 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 89-345 Range on HMM: 1-305/305 Sequence Identity: 35% (107 aa) YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLS------EKDKQILLQELALLKSIDHPNILKILEHYED-DQHHFFVTELLSGGELFTKIMELN | |.| ||.|.|||| .. | | | ||| ..| ... |.. . |. || . ||.| .|.. ... .. ..| || .||||| || . YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK G----FNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKK----------------SDQIKVIDFGCSTKFDKAKKIKDIAGTVLYLAPEVIKK . |.|... | .|.. ||.| | ..|.||||||||||. ... |..||. ||| | .. | || .|.||||| . RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS N---------------LYDEKCDIWSLGVVLYIMLCGYPPFD-GKND----EEVFNSIQN-KQVQFEGKEWEKISVQAKDLIEKMLQKDPNLRISAQQAY . | |.|.||.|..|||.|||||||. .. . | .| | |. ..| .|| ||||| .||. ||. |... .| KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL QHPWI .|||. NHPWM |
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| Kinase | 10025.AA | Ciliate-E2-Unclassified | 89-345 | 30 | 1.4e-90 | 307.21 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 89-345
Range on HMM: 1-352/352
Sequence Identity: 30% (109 aa)
YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSE------KDKQILLQELALLKS------------------IDHPNILKILEHYEDDQHHFFV
|...| .||||||.|. ..| .. . |.|. .|. || .|....... . ..||.|.| ... .|.|. ..|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV
TELLSGGELFTKIMELNG-----------------FNEAQAS-----GYMRQILSAVSYCHQQN-IVHRDLKPENILFTSKKS-DQIKVIDFGCSTKFD-
.|.. ||.|. | . .. | | ||. |..|||.. .|.|..| |.|||.|||||||..... .||.|||| | | .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
---------------KAKKIKDIAGTVLYL----APEVIKKNLYD----EKCDIWSLGVVLYIMLCGYPPFDGKNDEE----------------VFNSIQ
| .......|| |. ||||.... || .|||||||||.|| || ||.||...|.|. ... |.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK
NKQVQFEGKEW----EKISVQAKDLIE----KMLQKDPNLRISAQQAYQHPWI
.|..|| .| ..| .|||.|. |||.|.|| ||...|. .|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 10025.AA | RSK | 92-345 | 35 | 7.2e-83 | 281.61 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 92-345 Range on HMM: 1-278/278 Sequence Identity: 35% (99 aa) GKFLGQGGFGTVCVGIQKV----TNVKRAIKMVSKVTLSEKDK--QILLQELALLKSID-HPNILKILEHYEDDQHHFFVTELLSGGELFTKIMELNG-- | |||||.| | . .|. |. | | ..| .. ..| ..| |. . ||.| . . ...... . ..|...||||||.. . LKVLGQGGYGKVFL-CRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFG -FNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKK-SDQIKVIDFGCSTKF--DKAKKIKDIAGTVLYLAPEVIK---KNL-YDEKCDIWSLG | | |. ||..| .||.. ||| |.||||||||||..... . ||..||| . .| |. .. . .|. |.|||..| .. .|. ||.|||| CFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VVLYIMLCGYPPFDG---KNDEEVFNSIQNKQVQFEGKEWEKISVQAKDLIEKMLQKDPNLRIS-----AQQAYQHPWI |..| || |.||| | .| .|... ||... .....|...| ||||| |||..||. |.. |.. ||||. VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 10025.AA | TyrKc | 89-343 | 20 | 7.2e-17 | 50.04 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-280/280 Sequence Identity: 20% (60 aa) YTMGKFLGQGGFGTVCVGIQKVTNVKRAIKMVSKVTLSEKDKQILLQELALLKSI--DHPNILKILEHYEDD-------QHHFFVTELLSGGELFTKIME |.|| || | ||.|. |. | .. |.||. . . .. ...|. ..... .||||.... .. . .. |.|. ..| | . . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK LNG-FNEAQASGYMRQILSAVSYCHQQNIVHRDLKPENILFTSKKSDQIKVIDFGCSTKFDKA------KKIKDI----AGT----VLYLAPEVIKKNLY . .. .. .. || . .| |..|..|||| |.| .... ..|. ||| | . . |. .. | . .|||.|... . HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF DEKCDIWSLGVVLY-IMLCGYPPFDG-----KNDEEVFNSIQNKQVQFEGKEWE------KISVQAKDLIEKMLQKDPNLRISAQQAYQHP .| |.|| ||... |. | .| | ....||.. ... .. . . . .... . ||. | . .. .. TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 10025.AA | Pkinase_Tyr | 89-212 | 24 | 2.8e-14 | 48.96 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 89-212 Range on HMM: 1-137/270 Sequence Identity: 24% (34 aa) YTMGKFLGQGGFGTVCVGIQK----VTNVKRAIKMVSKVTLSEKD--KQILLQELALLKSI-DHPNILKILEHYE-DDQH--HFFVTELLSGGELFTKIM |.|| ||.| ||.|. |. | |... |.||. | . .... .. ...|....|.. .||||.. . .... .. |.|. .| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR E----LNGFNEAQASGYMRQILSAVSYCHQQNIVHRDL . . .. . .. .|| .. .| ...|..|||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | 10025.AA | Pkinase_Tyr | 254-301 | 33 | 2.7e-07 | 25.35 | Pfam | 181-231 (270) | Show / Hide |
Range on Protein: 254-301 Range on HMM: 181-231/270 Sequence Identity: 33% (17 aa) LAPEVIKKNLYDEKCDIWSLGVVLYIMLC-GYPP-FDGKNDEEVFNSI-QN .|||.|. . . .| |.|| ||... .. | | . | .|||.. | .. MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED |
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| EFh | 10025.AA | EFh | 391-419 | 34 | 3.9e-05 | 24.3 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 391-419 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) QIFQNFIELDKDGDGQLSKEELIEGYERL .. . | ..||||||....||.... .| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10025.AA | efhand | 391-419 | 41 | 4.4e-05 | 23.01 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 391-419 Range on HMM: 1-29/29 Sequence Identity: 41% (12 aa) QIFQNFIELDKDGDGQLSKEELIEGYERL .. . | |.||||||....||..|....| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | 10025.AA | efhand | 429-457 | 34 | 5e-06 | 26.42 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 429-457 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) IVEYVFKEIDYDGSGKVSFQEFLVATASK .. .|||.| ||.|...|.||. . ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 10025.AA | EFh | 429-457 | 31 | 1.1e-05 | 26.11 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 429-457 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) IVEYVFKEIDYDGSGKVSFQEFLVATASK .. .|...| ||.|...|.||... .|. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10025.AA | efhand | 465-493 | 24 | 1.1e-05 | 25.26 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 465-493 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) NLYKAFDLIDEDRNGQITKDELQRVIGGT | ..|...| |..|.|...|..... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 10025.AA | EFh | 465-493 | 20 | 3.5e-05 | 24.47 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 465-493 Range on HMM: 1-29/29 Sequence Identity: 20% (6 aa) NLYKAFDLIDEDRNGQITKDELQRVIGGT . ..|...| |..|.|...|..... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 10025.AA | EFh | 499-527 | 34 | 5.6e-07 | 30.42 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 499-527 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) VWEQMMKECDVNGDGQINKQEFVDLMLKW ...|... |..|||.|...||.|.| . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10025.AA | efhand | 499-524 | 42 | 7.4e-07 | 29.52 | Pfam | 1-26 (29) | Show / Hide |
Range on Protein: 499-524 Range on HMM: 1-26/29 Sequence Identity: 42% (11 aa) VWEQMMKECDVNGDGQINKQEFVDLM ...|.|| |..|||.|...||...| ELKEMFKEFDKDGDGYIDFEEFCEMM |
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