Gene 5683 (Tetrahymena)
5683
Group:
CAMK
Family:
CAMK-Unique
Sequence
Protein domains of 5683.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 5683.AA | CAMK-Unique | 94-353 | 30 | 1.9e-146 | 486.62 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 94-353
Range on HMM: 1-363/363
Sequence Identity: 30% (111 aa)
YKMIKLIGKGSFGKVRLATN-VNGKEFAVKSILKADAG-ERYYL------------------LRRELDIMKKVDHPNLVKFYET----YHDDK-------
|||...||.|.||.|. ... ..||..|.|.. |...| ..... |.||..|.|.|||||..|.|.. ..|.|
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------YLHIVMEFVQGKELSQYCQERFE----------------VNRKFTE--SEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINES-------
|..||||..||..|....|...| ....|.| ....||...||||...||...|.|||.||||||...|
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------NLDVKILDFGLSRDFSQSQAS-ILQSIVGTPLYVAP--------------EVINEQPYDQKS----DSWSMGVLMYYLISGSHPFEASNIK-
|...|..||||.......... ..|...|||.|.|| ||||.|.|||.. |.||.||.|||...|..||......
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------ELFKNICSANF-NFRSSAWSG---ISKSAKVLITQFLNLDPKSRISCEEALQSDWF
|.|..||.... ||....|.| ||..||.........||..|.|..|.|...|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 5683.AA | CAMK | 99-353 | 23 | 4.1e-113 | 365.95 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 99-353
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)
LIGKGSFGKVRLATNV-NG------------KEFAVKSILKADAGERY---------------------------YLLRRELDIMKK-------VDHPNL
.|.||||||.|... .. ...|.| | | . . .|||..|||| .||||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKFYETYHD-------------------DKYLHIVM---EFVQGKELSQYCQERFEVN---------------RKFTESEVAFIVRKLLSALSHMHNLGI
.|.||.| | ||....|| |...| || ... .. . ..|||.|.....| ..||. ..|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDIKLENIMINESN----------------LDVKILDFGLSRDFSQSQASI----------------------LQSIVGTPLYVA-PEVIN-------
.|||.|.|||.....| ..|| |||... | ... . .. .||| |.| |||.|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------EQPYDQKSDSWSMGVLMYYLISGSHPFEAS-------------NIKELFKNICSANFNFRSSA------------WSGISKS--------AKV
...|..|.| ||.||..| . .| ||... |..|||..|......| .. |..||.. .|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LITQFLNLDPKSRISCEEALQSDWF
|| . |. ||. |...|..|. |.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 5683.AA | Ciliate-E2a | 94-353 | 36 | 7.6e-110 | 324.5 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 94-353
Range on HMM: 1-275/275
Sequence Identity: 36% (102 aa)
YKMIKLIGKGSFGKVRLATNVN-GKEFAVKSILKADAGER--YYLLRRELDIMKKVDHPNLVKFYETYHDDKYLHIVMEFVQGKELS---QYCQERFEVN
|| ||.||||.||.|.||. . ||.||.| . |... . . . .|..||...||||. |.||.| |.... .|||...|.|| ..|. ||
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE-
RKFTESEVAFIVRKLLS-ALSHMHNLGIIHRDIKLENIMIN---ESN---LDVKILDFGLSRDFSQSQASILQSIVGTPLYVAPEVINEQP------YDQ
. |.. | ..||. .|..||...|.|||.|.|||... .. .|.|| ||||...... . . ...||| ||||||.| ||.
----IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDT
KSDSWSMGVLMYYLISGSHPFEASNIKELFKNICSANFNFRSSA-WSGISKSAKVLITQFLNLDPKSRISCEEALQSDWF
| | || || .| |..|. ||.. . .| .... ...| .. |. .||..| |. . |. ||| ||....||.. ||
KCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
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| Kinase | 5683.AA | CDPK | 94-353 | 37 | 7.4e-97 | 297.59 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-271/271 Sequence Identity: 37% (103 aa) YKMIKLIGKGSFGKVRLATNV--NGKEF-AVKSILKADAGERY--YLLRRELDIMKKVDHPNLVKFYETYHDDKYLHIVME--FVQGKELSQYCQERFEV ||. | .|||.|| ||.... .. | |.| | | . . . .|..|.|. |||| .|.||.|.|.|. .|||| .. | || .| .|. YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEK--- NRKFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIM--INESNL----DVKILDFGLSRDFSQS---QASILQSIVGTPLYVAPEVINEQPYDQKSD ..||| | | |.|..|||....|. .|.|||.| |||. ..... ..|. |.|.|..| |. . . ..|||.|.||||.. . |..|.| -GHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCD SWSMGVLMYYLISGSHPFEASNIKELFKNICSANFNFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQSDWF || || .| |..|. || . | .| .... ...| |. ||..|| || . |. ||| |.|...||| || IWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 5683.AA | S_TKc | 94-353 | 34 | 3.2e-96 | 326.89 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-231/231 Sequence Identity: 34% (93 aa) YKMIKLIGKGSFGKVRLATNVN-GKEFAVKSILKADAGERYYLLRRELDIMKKVDHPNLVKFYETYHDDKYLHIVMEFVQG--KELSQYCQERFE--VNR |.....||||.||||....... |...|.| | .|||..|.|| .|||.||.|....| ..|..|||.. | .| .| ..| .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF KFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLDVKILDFGLSRDFSQSQASILQSIVGTPLYVAPEVINEQPYDQ-KSDSWSMGVLMYY .|.| ...|... ...|| ..|..||||||.| |||...| .|| ||||.| . ...||| |.||||. .|. |.| || |...| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE LISGSHPFEASNIKELFKNICSANFNFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQ-------SDWF ...| ||. .....||.|. |..|| .| . |. ||. |... |||| || MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 5683.AA | CAMKL | 94-353 | 30 | 2.2e-95 | 304.88 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-297/297 Sequence Identity: 30% (92 aa) YKMIKLIGKGSFGKVRLATN-VN-GKEFAVKSILKADAG-ERYYL-------------LRRELDIMKKVD---HPNLVKFYETYHDDKY------LHIVM |...| .||||||||.|||. . |.. |.| | | . . . . .||| |||... ||| .|.||.. .... ...|| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EFVQGKE--LSQYCQERFEVNRKFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNL-DVKILDFGLSRDFS---QSQASILQSIVGTPLYV | ..| | | .| ... .......|.| .. | ..||....|..||.|||||.|||.. |.. .|| |||.| . | |.| | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEVINE--QPYD-QKSDSWSMGVLMYYLISGSHPFEAS--------NIKELFKNICSANFNFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQSD |||... .||| .| | ||.||..| .. | ||.. || .|.. | . .... |. .| ... || . |. .|. |..... .. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP WF |. WM |
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| Kinase | 5683.AA | CAMK1 | 94-353 | 38 | 3.9e-94 | 274.03 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-276/276 Sequence Identity: 38% (109 aa) YKMIKLIGKGSFGKVRLATNVN----GKEFAVKSIL-KA-DAGERY---YLLRRELDIMKKV---DHPNLVKFYETYHDDKYLHIVMEFVQGKELSQYCQ |. .| ||.|.|..|.|.|. . ||..|.| | | .... ..|..|..||||| |||| .|||| | .|.....||| |.| || YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGEL----F ERFEVNRKFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLD--VK--ILDFGLSRDFSQSQASILQSIVGTPLYVAPEVINE---QPYDQ .| . ..|| . . |....|||. .|| .|| |||.| ||. | .| | |||||. |.. ... .||| ||||||.. .|||. DRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-LMKTACGTPGYVAPEVLECKKDKPYDK KSDSWSMGVLMYYLISGSHPFEASN-IKELFKNICSANFNFRSSAWSGISKS-AKVLITQFLNLDPKSRISCEEALQSDWF . | || || | | | || ..| ..|||. | .. ..| | | ||.. || .|.. |..||| |..||..|. |. ACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 5683.AA | Ciliate-E2 | 94-353 | 25 | 1.1e-89 | 304.21 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-365/365 Sequence Identity: 25% (97 aa) YKMIKLIGKGSFGKVRLATN------------------------VNGKEFAVKSILKAD---AGERYYLLR---------RELDIMKKVDHPNLVKFYET || ||.||.|.||.|..... |..|..|.|.. | . ...| |. |.....|||..|.||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YH--DDKYLHIVMEFVQGKELSQYCQER--FEVNR-----KFTESEVAFIVRKLLS---------------ALSHMHNLG-IIHRDIKLENIMINESNLD . ||... .|||..||..| .|.... .. . .||| |...| ...|. || ..|. . |||||||.|||.. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ VKILDFGLSRDFSQS------------------------------QASILQSIVGTPLYVAPEVINEQP---------YDQKSDSWSMGVLMYYLISGSH .|| |||||...... | . ..|.||| |.|||..| .. || |.| ||.||..|....| . IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFEASNIKELFKNICSANFNFRSS--------------AWSGISKSAKVLITQ----FLNLDPKSRIS-CEEALQSDWF || ...|. ...|.. | .|...| || . |. ||. ||. |..|. || PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 5683.AA | Pkinase | 94-353 | 31 | 4.9e-88 | 303.59 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-293/293 Sequence Identity: 31% (93 aa) YKMIKLIGKGSFGKVRLATNVNGKE-FAVKSILKADAGE--RYYLLR-RELDIMKKVDHPNLVKFYETYHDDKYLHIVMEFVQGK----ELSQYCQERFE |. .. ||.||||.|....... . .||| | | .. . .....| .|. |||...||| |..|....|......|||...| .|. | . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W VNRKF--TESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLDV----KILDFGLSRDF-SQSQASILQSIVGTPLYVAPEVIN-EQPYDQKSD ...| .| |. |... .|..| ..|. ||||||.|.|||.|. .| .. || ||||.. | .. .....||| |.|||||. |.|..|.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD SWSMGVLMYYLISGSHPFEAS------NIKELFKNICSANFNFRSSAWSGIS-----------------KSAKVLITQFLNLDPKSRISCEEALQSDWF ||.|...|....| || . . ......| .. . | .. |. || ...| .|. |..|||.|...|..||..|| MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 5683.AA | Ciliate-E2-Unclassified | 94-353 | 26 | 1.4e-82 | 280.69 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-352/352 Sequence Identity: 26% (94 aa) YKMIKLIGKGSFGKVRLATNVNGKEFA-------------VKSILK----------ADAGERYYLLR---RELD-IMKKVDHPNLVKFYETYHDDKYLHI ||.|| ||.|.||||... . . | .. .|.|.. . | | .... |.. .||..||.... |.... | YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI VMEFVQGKELSQYCQ-------------ERFEVNRKFTESEVA-----FIVRKLLSALSHMHNLG-IIHRDIKLENIMINESNL--DVKILDFGLSRDFS |||...|..|.||.. .. . ...||| ... |. . .|..|...| . |||||||.|||...... .|| |||.|. VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ QS--------------QASILQSIVGTPLYV----APEVINEQPYD----QKSDSWSMGVLMYYLISGSHPFEASNIKE----------------LFKNI |. . ......||| | ||||. .| || |.| ||.||..|... | .||.. | .. |..|| QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI CSANFNFRSSAW----SGISKSAKVLIT----QFLNLDPKSRISCEEALQSDWF . |..|... | ..|..|| .|. . |. .|..||. |..|. || KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 5683.AA | RSK | 97-353 | 30 | 8.9e-82 | 277.99 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 97-353
Range on HMM: 1-278/278
Sequence Identity: 30% (85 aa)
IKLIGKGSFGKVRLATNV----NGKEFAVKSILKADAGER---YYLLRRELDIMKKVD-HPNLVKFYETYHDDKYLHIVMEFVQGKELSQYCQERFEVNR
.|. |.|..||| | . .|...|.| . || . | ..| .|.. . ||..|. .........|...||.. | || .. . .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGEL----FTHLQKEK
K---FTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINE--SNLDVKILDFGLSRDFSQSQASILQSIVGTPLYVAPEVIN---EQP-YDQKSDSW
|.|.|..|. ... .|..|.| .||||||.|.|||. .. .. .|. |||... |. .. . ... ..| |.|||... | .|. | |
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWW
SMGVLMYYLISGSHPFEA---SNIKELFKNICSANFNFRSSAWSGISKSAKVLITQFLNLDPKSRIS-----CEEALQSDWF
| ||||| . .| || . .| ||..|.|....|.... .|. .|. || ||.. | ||. |.. || .|. ||
SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
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| Kinase | 5683.AA | MARK | 94-353 | 35 | 9.6e-81 | 263.68 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-262/262 Sequence Identity: 35% (95 aa) YKMIKLIGKGSFGKVRLATNVN-GKEFAVKSILKADAGE-RY-YLLRRELDIMKKVDHPNLVKFYETYH--DDKY-LHIVMEFVQGKELSQYCQERFEVN |||.| ||.||..||.||.... |...|.| . | . . ..||..||||.|||| .|.... . . ....|| . |.|| .| ... .| YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAH--PN RKFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESN-LDVKILDFGLSRDFSQSQASILQSIVGTPLYVAPEVINEQPYD-QKSDSWSMGVLM .. .|.| | | ..||.. .|. .|.|||||.|||.| | . ..|| |||.|. . | | . ||| | |||... .||| .| | ||.||.. GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK--LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVL YYLISGSHPFEASN--IKELFKNICSANFNFRSSAWSGISKSAKVLITQFLNLDPKSRISCEEALQSDWF |....|. ||.... .|||.|.| . .. . . .||... || ..|...|. |...|| .. |. YFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 5683.AA | TyrKc | 94-353 | 23 | 8.5e-17 | 48.85 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 94-353 Range on HMM: 1-280/280 Sequence Identity: 23% (68 aa) YKMIKLIGKGSFGKVRLATNVNGKEFAVKSILKADAGERYYLLRRELDIMKKV--DHPNLVKFYETYHDD-------KYLHIVMEFVQGKELSQYCQERF ...| .| | ||.|...| . |||.. . ..||. ||.|. .|||.|..| .. . | ||||.. . | .| ... ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR EVNRKFTESEVAFIVRKLLSALSHMHNLGIIHRDIKLENIMINESNLDVKILDFGLSRDFSQS----QASILQSI---VGTP--L---YVAPEVINEQPY . .. .. . . .. | ..||||. |....| . ||| ||||||| .. . |. | |||.||. . PK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF DQKSDSWSMGVLMYYLIS-GSHPFEA-----SNIKELFKNICSANFNFRSSA-----WSGISKSAKVLITQFLNLDPKSRISCEEALQSDWF ||| || ||.|. . . | | . . .|..... . . . . .. ...| . ||..| . .| . | TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 5683.AA | Pkinase_Tyr | 94-155 | 30 | 1e-12 | 43.67 | Pfam | 1-70 (270) | Show / Hide |
Range on Protein: 94-155 Range on HMM: 1-70/270 Sequence Identity: 30% (22 aa) YKMIKLIGKGSFGKVRLATNV-----NGKEFAVKSILKADAGERY---YLLRRELDIMKKV-DHPNLVKFY ...| .|.|.||.|...| .. . |||.. | .| .. . ||. |||. .|||.|..| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY |
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| Kinase | 5683.AA | Pkinase_Tyr | 263-286 | 58 | 0.005755 | 10.67 | Pfam | 182-205 (270) | Show / Hide |
Range on Protein: 263-286 Range on HMM: 182-205/270 Sequence Identity: 58% (14 aa) APEVINEQPYDQKSDSWSMGVLMY |||.||. . ||| || ||||. APECINYGKFTTKSDVWSFGVLMW |
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| Kinase | 5683.AA | Pkinase_Tyr | 204-243 | 40 | 0.006684 | 10.45 | Pfam | 122-160 (270) | Show / Hide |
Range on Protein: 204-243 Range on HMM: 122-160/270 Sequence Identity: 40% (16 aa) SALSHMHNLGIIHRDIKLENIMINESNLDVKILDFGLSRD ..... .. ..||||. |....| |. ||| ||||.|| KGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLARD |
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| Efhand | 5683.AA | efhand | 407-435 | 37 | 2.7e-05 | 23.81 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 407-435 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) KLKIAFETIDTDDNGYISAEELFKATQQL .|| .|. .|.| .|||. ||. .. ..| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 5683.AA | EFh | 407-435 | 34 | 0.000193 | 22.0 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 407-435 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) KLKIAFETIDTDDNGYISAEELFKATQQL ..| .|. .|.| .|||. ||. .. . | EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 5683.AA | EFh | 499-527 | 31 | 5.5e-05 | 23.81 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 499-527 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KINQLFSHFDKDGDNFISPQDLEDTFAQE .....|..|||||| .|..... | .. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 5683.AA | efhand | 499-527 | 27 | 6.8e-05 | 22.33 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 499-527 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) KINQLFSHFDKDGDNFISPQDLEDTFAQE .....|..|||||| .|. ... . ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 5683.AA | EFh | 535-563 | 31 | 3.9e-08 | 34.28 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 535-563 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) SIRQMIEEVDVDGDGKISQQEFLQLVQQE ...|....|.||||.|. .||..... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 5683.AA | efhand | 535-563 | 34 | 2.1e-07 | 31.52 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 535-563 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) SIRQMIEEVDVDGDGKISQQEFLQLVQQE ...|..|.|.||||.|. .||...... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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