Gene 9913 (Tetrahymena)

9913

Species: Tetrahymena
Alias: 9913, 601, TTHERM_00275720, PreTt09913, 24.m00344, 3690.m00153
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK-Tt

Sequence

Name Sequence Type Origin Length Description Download
9913.AA Protein None 667 None Fasta, JSON
9913.kin_dom Protein Kinase Domain None 265 None Fasta, JSON
9913.NA RNA None 2004 None Fasta, JSON

Protein domain

Protein domains of 9913.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9913.AA CAMK-Tt 144-310 68 1.4e-133 450.1 In-house 225-396 (396) Show / Hide 
Range on Protein: 144-310
Range on HMM: 225-396/396
Sequence Identity: 68% (117 aa)

IASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQCVKITDFNISKFG---STTKKDKFFN-KNVKMWTYTGTVSFSAPEVFSEDE-YDQSVDIWSA
.||.||||||..|.||||..||||||||||||..|||.||||||||.|||.   ...|||...| .|.|||||||||.|||||.|.||. ||...|.|||
VASKIFKQILDAIKYMHENYVCHRDLKPNNILCNEDGTCVKITDFNVSKFCDHYKNYKKDNLMNHQNIKMWTYTGTVAFSAPEIFNEDCCYDETIDMWSA

GVVLYTMLSGQEPFQAEYLQDLIAKIQNADYQFQSHIWSAISDEAKDLIQKCLILNPKERITPDQALLHPWI
|..|||||.|||||||||..|||.||..|||.|.||.|..||.||||||.|||..||..||.|||.|.||||
GCILYTMLCGQEPFQAEYVHDLIKKICQADYNFPSHVWQHISEEAKDLIKKCLTINPEQRIKPDQMLQHPWI
Kinase 9913.AA CAMK 51-310 23 1.3e-100 324.92 In-house 1-425 (425) Show / Hide 
Range on Protein: 51-310
Range on HMM: 1-425/425
Sequence Identity: 23% (99 aa)

ILGEGCVGLVKKVKRISDG------------ELFACKMVKLK----------------------------DEETVLQVIREFKNIKK-------LNHPNI
.||.|  | ||........            . .|.|... |                            ....  .| || .  ||       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRVYELYVD----------EIKRR--------IYTIM---ELVEASEM----FEVIRKLGS---------------YSEEIASRIFKQILSCIRYMHESC
.. || | |          |  ..        .| .|   |...  |.    |. |.. |.               ..|. |.|.|.||.| ..|.|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VCHRDLKPNNILSTEDG----------------QCVKITDFNISKFGSTTKKDK---------FFNK-------NVKMWTYTGTVSFSA-PEVFS-----
..|||||| ||| ....                  .||.||  ...    ....         . ..       . ||.|. || .. | |||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEM-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------EDEYDQSVDIWSAGVVLYTMLSGQEPFQAE-------------YLQDLIAKIQNADYQFQSHI------------WSAISDE--------A
         .. |....|.||.||.||.||.|  ||...              ...|  ||....|.| ..             |. ||||        .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KDLIQKCLILNPKERITPDQALLHPWI
||||.|.|  .|..|.| .|.| |||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 9913.AA S_TKc 46-310 31 1.4e-85 291.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-231/231
Sequence Identity: 31% (88 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEETVLQVIREFKNIKKLNHPNIVRVYELYVDEIKRRIYTIMELVEA--SEMFEVIRKLGS----
.| |...|.|  | |.|.. ...|...|.|..|        ...|| .  || .|||||. |. ..|    ..| .||...    ..|..|.| |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQCVKITDFNISKFGSTTKKDKFFNKNVKMWTYTGTVSFSAPEVFSEDEYDQ-SVDIW
  ..|  | ....||.. . |.|.  ..|||||| ||| .|   ..||.|| ....                 |. ||  . ||||.    |.  ..|.|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---GYGKCKCDWW

SAGVVLYTMLSGQEPFQAEYLQDLIAKIQNADYQFQSHIWSAISDEAKDLIQKCLILNPKERITPDQALL-------HPWI
| |..|| ||.|. ||.   .| .. ||               |.||||.|.|||  .|..|.|  .||        |||.
SCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 9913.AA Pkinase 46-310 31 1.8e-82 285.11 Pfam 1-293 (293) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-293/293
Sequence Identity: 31% (97 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEETVLQVI----REFKNIKKLNHPNIVRVYELYVDEIKRRIYTIMELVEAS----EMFEVIR--
.. . ..|.|  | |.| .....|...|.| .|...|.   ...    .| .  |.|||||||| |. . |  |..|| .||..|      . |..|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

KLGSY--SEEIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQC---VKITDFNISKFGSTTKKDKFFNKNVKMWTYTGTVSFSAPEVFS-EDEY
. |..  ||. . ....|||. . |.|.  ..|||||| |||  ..|..   |||.|| ..|. .         .|. |.|..||  . ||||     .|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEVIRGGQYY

DQSVDIWSAGVVLYTMLSGQEPFQAE------YLQDLIAKIQNADYQFQSHIWSAIS-----------------DEAKDLIQKCLILNPKERITPDQALL
...||.||.|..|| ||.|. ||. .        . .|..|  ... |..  |. ||                 .|.||.| .|| ..||.|.|..|.| 
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

HPWI
|||.
HPWF
Kinase 9913.AA Ciliate-E2 46-310 24 3e-79 269.61 In-house 1-365 (365) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

FEELDILGEGCVGLVKKVKRISDGELFA-----------------------CKMVKLKDEETVLQVIREFKNIK-------------KLNHPNIVRVYEL
.. . ..|.|. | |.|.|.......||                        |..| .. | ..|.|.... |.             .||||||.. || 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YVDEIKRRIYTIMELVEASEMFEVIRKL-----------GSYSEEIASRIFKQILS---------------CIRYMHESC-VCHRDLKPNNILSTEDGQC
. .. .  || .||...  ..|. |..            ....|. ...|.||||.               ...|.|.   ..|||.||.|||       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VKITDFNISKF----------GSTTKKDKFFN--------------KNVKMWTYTGTVSFSAPEVFSEDE---------YDQSVDIWSAGVVLYTMLSGQ
.||.|| .||.          ..  |. .| .              .    .|. ||  . |||...  .         || ..||||.||.|| ||.|.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

EPFQAEYLQDLIAKIQNADYQFQSH--------------IWSAISDEAKDLIQK----CLILNPKERIT-PDQALLHPWI
 ||        . .|.. ...|..               .|  .|.|.||||.|    .|  .|..||| ..|.| |||.
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 9913.AA Ciliate-E2-Unclassified 46-310 27 1.3e-77 264.12 In-house 1-352 (352) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

FEELDILGEGCVGLVKKVKRISDGELF-----AC-------KMVKLKDEETVLQVIREFK---NIKK----------LNHPNIVRVYELYVDEIKRRIYT
.. . ..|.|. | |.|....... ..     ..       | .. || | ... .....   .. .          ||||....|...|... |  || 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMELVEASEMFEVIRKLGS-----------------YSEEIAS-----RIFKQILSCIRYMHESC-VCHRDLKPNNILSTEDGQ--CVKITDFNISK-FG
.||..|  .... |.| ..                  .|. |.     ..|.|||... |.|..  ..|||.||.||| ...|.  ..||.|| |||  .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

STTKKDKFFN-------KNVKMWTYTGTVSFS----APEVFSEDEYDQS----VDIWSAGVVLYTMLSGQEPFQAEYLQD----------------LIAK
.  ..| ...       |. .||| .|| ..     ||||. . .||.|    .|||| ||.|| || |. ||...   .                |. .
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

IQNADYQFQSHIW----SAISDEAKDLIQ----KCLILNPKERITPDQALLHPWI
|.. ..||... |      .|.||||.|.    |.|  ||..|||..|.| |||.
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 9913.AA CDPK 46-310 37 3.5e-77 236.29 In-house 1-271 (271) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-271/271
Sequence Identity: 37% (105 aa)

FEELDILGEGCVGLVKKVKRI-SDGELF-ACKMV---KLKDEETVLQVIREFKNIKKLNHPNIVRVYELYVDEIKRRIYTIME--LVEASEMFEVIRKLG
.   ..||.|  | |.|||   ....   | |..   ..||.|   |...|..  |.| ||||...|| | ||  . .| .||  ...  | |..|   |
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDE--KNYYIVMETEYCTGGELFDYIIEKG

SYSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNIL--STEDGQ----CVKITDFNIS-KFGSTTKKDKFFNKNVKMWTYTGTVSFSAPEVFSEDEYDQ
...|  |. |..|||| . |.|.  ..|||||| |||  | .|..     .|. |. .| ||..   |      . || .  ||.   ||||     |..
HFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQN-QKI----EDKKMSQRCGTPYYIAPEVLQKK-YNE

SVDIWSAGVVLYTMLSGQEPFQAEYLQDLIAKIQNADYQFQSHIWSAISDEAKDLIQKCLILNPKERITPDQALLHPWI
..||||.||.||..|.|  || ..  |. ..|...  |.|    |. |||||||||.|.|  .|| |.. .||| |||.
KCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 9913.AA CAMK1 46-310 35 8.2e-77 222.8 In-house 1-276 (276) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-276/276
Sequence Identity: 35% (101 aa)

FEELDILGEGCVGLVKKVKRIS---DGELFACKMVK-LK--DEETV---LQVIREFKNIKK---LNHPNIVRVYELYVDEIKRRIYTIMELVEASEMFEV
.|  ...|.|  . |.......   .|. .| |. .  |  .....    .. .|    ||   ..||||.  || |  | .. .| .||||   | |. 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWY--ESDNHFYLVMELVTGGELFDR

IRKLGSYSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNIL--STEDGQCVK--ITDFNISKFGSTTKKDKFFNKNV-KMWTYTGTVSFSAPEVFSE--
| . |.|.|. |..| ||||| . |||.  ..|||||| |.|  . ...  .|  | || .|         |.|. .. .| |  || .. ||||.    
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLS---------KIFDHDENLMKTACGTPGYVAPEVLECKK

-DEYDQSVDIWSAGVVLYTMLSGQEPFQAEY-LQDLIAKIQNADYQFQSHIWSAISDE-AKDLIQKCLILNPKERITPDQALLHPWI
 . ||...|.||.||..|..| | .||..|   . | .|| ...| | |  |  |||. |||.| . | ..||.|.| .|.| ||||
DKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 9913.AA Ciliate-E2a 46-310 31 8.4e-74 216.62 In-house 1-275 (275) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-275/275
Sequence Identity: 31% (90 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEETV---LQVIREFKNIKKLNHPNIVRVYELYVDEIKRRIYTIMELVEASEMFEVIRKLGSYSE
.. ....|.|. | |...... .|. || | .. |....     ....| . ...|.|||| . || | ||    .| .||..|  |... |.. ... |
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENN--YYLVMEYCEGGELYDKIKQCKRFFE

E--IASRIFKQILS-CIRYMHESCVCHRDLKPNNILST---EDG---QCVKITDFNISKFGSTTKKDKFFNKNVK--MWTYTGTVSFSAPEVFSEDE---
|   ...| .|.|.  . |||  .. |||||| ||| .    ..   . .|| ||  .         .|..|. |  | .  ||  . ||||.   |   
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLA---------TFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLK

---YDQSVDIWSAGVVLYTMLSGQEPFQAEYLQDLIAKIQNADYQFQSHI-WSAISDEAKDLIQKCLILNPKERITPDQALLHPWI
   ||...|.||.||..|..|.|. ||...  .. . .. .  ..|.. . |. .|.|.|||..| |  .||.|||. ||| ||| 
HKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 9913.AA CAMKL 46-310 30 3.8e-69 219.75 In-house 1-297 (297) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-297/297
Sequence Identity: 30% (94 aa)

FEELDILGEGCVGLVKKVKRISD-GELFACKMVK---LKDEETVLQ------------VIREFKNIKKLN---HPNIVRVYELYVDEIK----RRIYTIM
.. .. ||.|  | ||  . |.  ||  | |...   ..... ...            . || .  |.||   ||||.. || . .. .      || .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELVEASE--MFEVIRKL----GSYSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQ-CVKITDFNISKFGSTTKKDKF-FNKNVKMWTYTG
|...  |  .|. |.|     |. .|. | |.|.||.| . |.|. ...|||.|| ||| .|.|   .||.|     ||  .. ..  |... |. |  |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIID-----FGFSNMYRPCIFGPGQKLKTFCG

TVSFSAPEVFSE--DEYD-QSVDIWSAGVVLYTMLSGQEPFQAEYL-------QDLIAKIQNADYQFQSHIWSAISDEAKDLIQKCLILNPKERITPDQA
. .. |||.|.   ..|| . |||||.||.||.|. |. || .. .       . .  .... .  ..  ||. .| ...|||.| |  ||..|.| .| 
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG--YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI

LLHPWI
. ||| 
MNHPWM
Kinase 9913.AA CAMK-Unique 46-310 23 1.1e-68 225.81 In-house 1-363 (363) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-363/363
Sequence Identity: 23% (89 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEETVLQVI--------------------REFKNIKKLNHPNIVRVYEL----YVDEIK------
 . . |.|.|  |.|.... .. | ..||||||... .   |..                    ||    |...||||...|.     ..|. .      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

-------RRIYTIMELVEASEMFEVIRK--------------------LGSYSE--EIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQ-----
        ..|..||.... ..|..| |                     |..||    ...|. ..|| . |||.  . |||||. ||.  . ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

----------CVKITDFNISKFGSTTKKDKFFNKNVK--MWTYTGTVSFSAP--------------EVFSEDEYDQSV----DIWSAGVVLYTMLSGQEP
           .|..|| ...        .. .. .   | |. || .. ||              ||  .. ||| .    |||| ||..|.||.|  |
RDFPYDWSNWHIKLCDFGLCC--------HYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPP

FQAEYLQ--------DLIAKIQNADY-QFQSHIWSA---ISDEAKDLIQKCLILNPKERITPDQALLHPWI
| .|            ....|  .||  | .  |.    ||.||||....|. . |. |..  ..| |.||
FDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 9913.AA CAMK-Tt 46-143 55 1.3e-65 224.29 In-house 1-137 (396) Show / Hide 
Range on Protein: 46-143
Range on HMM: 1-137/396
Sequence Identity: 55% (76 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEE-TV--------------------------------------LQVIREFKNIKKLNHPNIVRV
.||..|||||||||||||||||||..||||||...||| ..                                      .|||||||||..|||||||.|
YEEQEILGEGCVGLVKKVKRISDGQVFACKMVRTRDEEEIMNHQSYNSEISSGQHKCQSTGELFEITKFTYFKSISQSKMQVIREFKNIRELNHPNIVKV

YELYVDEIKRRIYTIMELVEASEMFEVIRKLGSYSEE
||||.||.|.||||||||.||.||||||.|||.|||.
YELYIDETKGRIYTIMELIEAKEMFEVIHKLGHYSEK
Kinase 9913.AA MSK 46-310 27 2.6e-63 212.86 In-house 1-277 (277) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-277/277
Sequence Identity: 27% (80 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVK-------LKDEETVLQVIREFKNIKKLNHPNIVRVYELYVDEIKRRIYTIMELVEASEMFEVIRKLG
 ..|  .|.| .....|. . ..| |.| | ..        | .|.. . ..  . ..  .|||||  .. . |. .   | .||..   |.|. ||| .
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQ--QHPNIVNLHYAFQDQCH--TYLVMEYCNGGELFTHIRKRE

SYSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTED--GQCVKITDFNISKFGSTTKKDKFFNKNVKMWTYTGTVSFSAPEVFS----EDE-YDQ
  .|. .. |. .. . ...||.  . |||||| ||| ...  .  ||..||  ..   . .... .        . .|  . |||.      .|. ||.
HFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKS-------PCFTLHYMAPEMLRRGYAQDGGYDE

SVDIWSAGVVLYTMLSGQEPFQ--AEYLQ-------DLIAKIQNADYQFQSHIWSAISDEAKDLIQKCLILNPKERITPDQALLHPWI
..|.|| ||.|||||.|| |||  ..  |       ..  .|. ..  |..  |. .| .||||||..|  .|| | . .  . | |.
ACDWWSLGVILYTMLTGQVPFQQNEDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase 9913.AA TyrKc 46-310 22 7.5e-14 1.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 46-310
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FEELDILGEGCVGLVKKVKRISDGELFACKMVKLKDEETVLQVIREFKNIKKL--NHPNIVRVYELYVDE-----IKRRIYTIMELVEASEMFEVIRKLG
 . ...||||. | | | . .   .  | ||.|      .   .|| .  .||  .|||||| |   ...         .. .||...     . .|| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

S-YSEEIASRIFKQILSCIRYMHESCVCHRDLKPNNILSTEDGQCVKITDFNISKFGSTT------KKDKFFNK--NVKMWTYTGTVSFSAPEVFSEDEY
   . .    .  || .  .| |. .. ||||   |.| .|.. .|||.||  |...         |. .   .  . |..     .   |||.. . ..
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM---LPIRWMAPECINYGKF

DQSVDIWSAGVVLYTMLS-GQEPFQA-----EYLQDLIAKIQNADYQFQSHI-----WSAISDEAKDLIQKCLILNPKERITPDQALLHPWI
    |.|| ||... ... ||.|           |..|..... ..  | .          .||  .....|   .|..| |  .   |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF