Gene 23838 (Tetrahymena)
23838
Sequence
Protein domains of 23838.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 23838.AA | MARK | 836-1092 | 51 | 2.2e-167 | 551.03 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-262/262 Sequence Identity: 51% (134 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKLDHSNIIKLYQTID--TRSS-VNLVMEYISSQSLRQFMKAQEGRQ .... .||.||||.||||...||...||||.|.|.|| |||...||.|||.|. |||| |||||...|. |.. ..|.|||.|...|....||.... YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSDKKLNIFCGTPSYMSPEITKKREYFGKPADVWSLGVVLYALV |.|. || ||.|.||||.|||.. ..|||||.||...| .||.||.|||||.|.||...|||.|||||.||.|||..|..| |...|.||||||||..| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV CGRFPFKGKD--DNDLFRKIQSGDFKIPGNVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF ||.|||.|.. ...|..||..|...|| .|| .. ||..||..|||.|||..|. | .. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 23838.AA | CAMKL | 836-1092 | 38 | 1.2e-137 | 441.92 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-297/297 Sequence Identity: 38% (115 aa) FEIKACIGKGSYAVVKLARD-THTDKNVAIKMYDKYKLI-DPQKRNN-----------VKREIAILNKLD---HSNIIKLYQTIDTRSS------VNLVM ..| .||||...||||.. .| . ||||..|| |. ||....| ..|||.|. .|. | ||||||..|.|.. ..||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYISSQS--LRQFMKAQEGRQ--LEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFA---IR--IPSDKKLNIFCGTPSYM ||.|. . | .. .....| ..|. || .|.|.||||.|||. ..|||||.||..|| ..|..||.|||||. .. .....||..|||.|.|| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM SPEITKK--REYFGKPADVWSLGVVLYALVCGRFPFKGKDDN-------DLFRKIQSGDFKIP--GNVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF .||| .. ..| |...|.||.||.|||.|||..||.. ..| |..|| .| ...| || .. .|| |.|. |||.|||.... . .. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 23838.AA | CAMK | 841-1092 | 26 | 1.4e-120 | 390.46 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 841-1092
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)
CIGKGSYAVVKLARDTHTD------------KNVAIKMYDKYKLID-------------------------PQKRNNVKREIAILNK-------LDHSNI
.|.||...|||.....| . ||||..|| || | |..| ||.|||.|..| ||| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKLYQTID------------TRSS--------VNLVM---EYISSQ----SLRQFMKAQEG-------------RQLEERYARLIFKQLVSAVQYCHEWE
||||.... | | . .|| ||.| | .. ..... . ..|| || .|.|..|||.|||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VIHRDIKLENVMLDISNN---------------HQIKLIDFGFAIRIPS------------------------DKKLNIFCGTPSYMS-PEITKK-----
..|||.|.||..|| .|. ..||.||||||..... ..|.. |||||.||. ||. ..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------REYFGKPADVWSLGVVLYALVCGRFPFKGK-------------DDNDLFRKIQSGDFK-IPGN-----------------------VSQSAT
..| |...|.||.||.||...||..|| |. .|..||.||..|.. .| |||..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
RLINKLLKLNPEDRPTAKEVNKNNFF
||.|.|. .||.|.|.... . ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 23838.AA | AMPK | 836-1092 | 36 | 9.2e-94 | 278.74 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-254/254 Sequence Identity: 36% (93 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKLDHSNIIKLYQTI-DTRSSVNLVMEYISSQSLRQFMKAQEGRQLE . |. ||.|.. ||.. . | . |||| .| |..| . . ..||| || .. | .||.||. | .| . .||||.| | . . |. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ ERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSDKKLNIFCGTPSYMSPEITKKREYFGKPADVWSLGVVLYALVCG || |. |.| .|.| |||. . ||| |.||. || |..||. ||| ..| || | | .||. . | | |.|| ||.|||..|| EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD--HNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCG RFPFKGKDDNDLFRKIQSGDFKIPGNVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF . || . .|..|| .|...|| ..|..| ||...|. .|. | | ... . .| YLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 23838.AA | S_TKc | 836-1092 | 33 | 8.3e-91 | 308.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-231/231 Sequence Identity: 33% (91 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKLDHSNIIKLYQTIDTRSSVNLVMEYISS--QSLRQFMKAQEG--- .|| ||||....|...|...|.. ||||. . ....|||.|| | .| ||.||| .... ... .||||.. .|....| . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL -RQLEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSDKKLNIFCGTPSYMSPEITKKREYFGK-PADVWSLGVVL ... | || ...|...|..|||. .||||.| ||..|| .||..|||.| .. . ||||| ||.||. .|| ..|.||.|..| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL YALVCGRFPFKGKDDNDLFRKIQSGDFKIPGNVSQSATRLINKLLKLNPEDRPTAKEVNK-------NNFF | ..||. || ... .|.|| |..| .|.|.|. .||.|||| |. . .| YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 23838.AA | Pkinase | 836-1092 | 26 | 2.6e-89 | 307.83 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-293/293 Sequence Identity: 26% (80 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVK-REIAILNKLDHSNIIKLYQTIDTRSSVNLVMEYISSQ----SLRQFMKAQEG ..|. .||.||...|..... | | ||.| .| . . ....... .||.|...|.| ||..|| . ..... .|||| .| ....... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RQL--EERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQI----KLIDFGFAIR--IPSDKKLNIFCGTPSYMSPEITKKREYFGKPADVW . . .|. .. ...|......|||. .||||.|.||...| || .| |..|||.| . .. .. ||||| ||.||. ....| |...|.| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SLGVVLYALVCGRFPFKGK------DDNDLFRKIQSGDFKIPGNVS---------------------QSATRLINKLLKLNPEDRPTAKEVNKNNFF |.|..|| ..|||.||.|. |.. ....| ..... . . ... .|...|...|..||||... . .| SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 23838.AA | NuaK | 836-1092 | 39 | 1.7e-88 | 232.7 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-252/252 Sequence Identity: 39% (102 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKLDHSNIIKLYQTIDTRSSVNLVMEYISSQSLRQFMKAQEGRQLEE .|.. ||| | ||||.. .|.. |||| | | |.| . ||| |. |.| .||. | .. . .|||| | | .. | ..| | YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYI--SECKSLPE RYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSDKKLNIFCGTPSYMSPEITKKREYFGKPADVWSLGVVLYALVCGR | || .| | |||| ||| ...||| ||||..|| .| .| ||| .| |. ||| | | |||| . | | | |||||.||..| | REARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCN--AKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGT FPFKGKDDNDLFRKIQSGDFKIPGNVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF || |.| . | . |..|.. | |. | || ..|. ||. | | .. . MPFDGHDFKHLVKQISQGAYYEPCKPSD-ACMLIRWMLMVNPRRRATIYDICHHWWV |
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| Kinase | 23838.AA | QIK | 836-1092 | 38 | 1.1e-79 | 271.01 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 836-1092
Range on HMM: 1-272/272
Sequence Identity: 38% (107 aa)
FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKLDHSNIIKLYQTIDTRSSVNLVMEYISSQSLRQFMKAQEGR----
..| |||| .||||||| | . |||| || .| | . . ..||..|. |.| .|||||| . | . .|.|| |. . . .. ||
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYL-CKHGRKGVK
---------------QLEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSDKKLNIFCGTPSYMSPEITKKREYFG
..|. || .|.|..|||.|||. ...|||.| ||..|| || ||..|||| ... |. .||.| | ||. . .|| |
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLD--NNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDG
KPADVWSLGVVLYALVCGRFPFKGKDDNDLFRKIQSGDFKIPGNVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF
.|.||.|||||.|||| .|| || .. | ... || |.|| .|| || . | ..|| | | . . .
PKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | 23838.AA | Ciliate-E2 | 836-1092 | 21 | 3.4e-79 | 269.42 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 836-1092
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)
FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKY-----------------KLIDPQKRNNVKREIAILN----------------KLDHSNIIKLYQT
... .||.|....|..... ..|..|||. |.. | . ... ...|.|| |.. .|.| ||||.| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
ID--TRSSVNLVMEYISSQSLRQFMKAQ----------EGRQLEERYARLIFKQLVS---------------AVQYCHEWE-VIHRDIKLENVMLDISNN
..... |||||.. ..|....| . . .. |. .. |.||... |..|.|. .||||||.||...
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
HQIKLIDFGFAIRIPSD-----------KKLNIF----------------------CGTPSYMSPEITKKREY--------FGKPADVWSLGVVLYALVC
||.||||.. .. | .... . |||| ||.||| .. .| .. .|.|||||.|| ...
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF
GRFPFKGKDDNDLFRKIQSGDFKIP------------------GNVSQSATRLINK----LLKLNPEDRPT-AKEVNKNNFF
|..|| ...|. .....| ..||.. ||.| .|. .|| |.| .... .. .|
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 23838.AA | Ciliate-E2a | 836-1092 | 32 | 4.4e-77 | 226.45 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-275/275 Sequence Identity: 32% (90 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQ-KRNNVKREIAILNKLDHSNIIKLYQTIDTRSSVNLVMEYISSQSLRQFMKAQEGRQLE .... ||||....|.||. | |. |.| .| |. . .. ....||.|. .||| |||||| . . .. |||||... .| . .| . . | YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE ERYARLIFKQLVS-AVQYCHEWEVIHRDIKLENVMLD--ISNN---HQIKLIDFGFAIRIPSDKK--LNIFCGTPSYMSPEITKKREY-----FGKPADV . ... | .|| . ...|.| ..|||.|.||.... .|. .||.||||.| .|..|.| . |||| |. ||. . .| .. |. IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WSLGVVLYALVCGRFPFKGKDDNDLFRKIQSG--DFKIPG---NVSQSATRLINKLLKLNPEDRPTAKEVNKNNFF ||.||..| |.||. |||||. |. . .. || .| ..|... |. |.|. .|. |.||.. .. .| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 23838.AA | Ciliate-E2-Unclassified | 836-1092 | 22 | 1.4e-70 | 240.82 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 836-1092
Range on HMM: 1-352/352
Sequence Identity: 22% (78 aa)
FEIKACIGKGSYAVVKLARDTHTDKNV-----AIKMYDKYKLIDPQKRNNVKREIAILNK-------------------LDHSNIIKLYQTIDTRSSVNL
..| .||.|....|..... .. . ..|. .. ... .| . ..|. ..|. ..| .|.|.. . .. . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI
VMEYISSQSLRQFMKAQEG---------------RQLEERYAR-----LIFKQLVSAVQYCHEWE-VIHRDIKLENVMLDISN-NHQIKLIDFGFAI---
||||. ..|.|..| ... ....|. |. .|.|.... .|.|. .||||||.||...| .. | .||.||||...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ
-------------RIPSDKKLNIFCGTPSYM----SPEITKKREYFG---KPADVWSLGVVLYALVCGRFPFKGKDDND----------------LFRKI
|....... |||||.|| .||. .. .| . . .|.|||||.||... |..||....... |...|
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI
QSGDFKIPG--------NVSQSATRLIN----KLLKLNPEDRPTAKEVNKNNFF
. .....| ..|..| .|| |.|| ||. |.|.... . .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 23838.AA | CAMK-Unique | 836-1092 | 24 | 9.9e-69 | 225.95 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 836-1092
Range on HMM: 1-363/363
Sequence Identity: 24% (90 aa)
FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDK-YKLIDPQKR----------------NNVKREIAILNKLDHSNIIKLYQT----IDTRS-------
. ||.|.. .|. . | .| | |.|| | . .. || . |||..|. ..|| ||||||.. .|
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------SVNLVMEYISSQSLRQFMKA-QE-----------------GRQLEE--RYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDIS-------
.||||. | . . . | ....| . ...|. .|.||| | |. ..|||.||||.|. |
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
-------NNHQIKLIDFGFAIRIPSDKKLN---IFCGTPSYMSP--------------EITKKREYFGKPA----DVWSLGVVLYALVCGRFPFKGKDDN
.|. |||.||| . . . |. ..||||.||.| |. . . | . . | |||||..| . ||. || . ...
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCY-DQQCSPASDIWSLGVIMYYMLCGCPPFDCECED
--------DLFRKIQSGDF-----KIPGN---VSQSATRLINKLLKLNPEDRPTAKEVNKNNFF
.|..| .||. | . .||.|. .. ..... | | .||| .. ..
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 23838.AA | TyrKc | 836-1092 | 22 | 9.7e-15 | 15.61 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 836-1092 Range on HMM: 1-280/280 Sequence Identity: 22% (66 aa) FEIKACIGKGSYAVVKLARDTHTDKNVAIKMYDKYKLIDPQKRNNVKREIAILNKL--DHSNIIKLYQTIDTR-------SSVNLVMEYISSQSLRQFMK . . .| | . .| ... . .||.|| ... | ||. |. || .| ||..|| . . . .|||| . .|... . ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR AQEGRQLEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRIPSD-----KKLNIFC----GTPS-----YMSPEITKKR . ... | . . | . .| |. .||||. |.. ...||..| ||| . | .| | . |. . |.|| ... KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL--VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG EYFGKPADVWSLGVVLY-ALVCGRFPFKG-----KDDNDLFRKIQSGDF-KIPGN--------VSQSATRLINKLLKLNPEDRPTAKEVNKNNFF . | |||| ||... . | | | ... ........|. ..| | .. ... . . .|||||| .|. .| K-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 23838.AA | Pkinase_Tyr | 836-1053 | 24 | 5.4e-11 | 37.86 | Pfam | 1-232 (270) | Show / Hide |
Range on Protein: 836-1053
Range on HMM: 1-232/270
Sequence Identity: 24% (58 aa)
FEIKACIGKGSYAVVKLARDT----HTDKNVAIKMYDKYKLIDPQ-KRNNVKREIAILNKL-DHSNIIKLYQTID-TRSS--VNLVMEYISSQSLRQFMK
.. .|.|.. .|.... . |. ||.|| | . ..| .| ||..|. .| .| ||..|| . . . . .|||| .|. . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
AQ--EGRQLEERYARLIFKQLVSAVQYCHEWEVIHRDIKLENVMLDISNNHQIKLIDFGFAIRI-------PSDK--KLNIFCGTPSYMSPEITKKREYF
.. ....| . | .. .| .. ||||. |.... |...| ||| | | . . || |. |.|| . .. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIK-----WMAPECINYGK-F
GKPADVWSLGVVLYALVC-GRFP-FKGKDDNDLFRKI-QSG
|||| ||... .. |. | ..| ........| ..|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
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| Kinase | 23838.AA | CAMKL | 1103-1113 | 18 | 0.145211 | 0.59 | In-house | 287-297 (297) | Show / Hide |
Range on Protein: 1103-1113 Range on HMM: 287-297/297 Sequence Identity: 18% (2 aa) KLKKILSDRWF ... |....|. TIHQIMNHPWM |
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