Gene 20819 (Tetrahymena)
20819
Sequence
Protein domains of 20819.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 20819.AA | MARK | 173-427 | 53 | 5.1e-168 | 553.12 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-262/262 Sequence Identity: 53% (139 aa) YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTID--TPKH-INLVMEYVGSSSLHSYLKLHTGRK | .. .||.||||.|||...| ..|||.| ||||||.|||..|||.|||.|..|||| ..||||..|. |..| |.|.|||... .|..|.| |.... YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQN--NVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAAGILLYVML |.|.||.|||.|.. ...|.||||.||||||.||||.|... |.|||||||||.|||..||..|||||.||||||. ||.|.|..||||. |..||.|. LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV CGTFPFR--GIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL ||.|||. ..|.|.|.|.|.||. ..|.|||.... |||..|..| .||. .. |.|. |. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 20819.AA | CAMKL | 173-427 | 39 | 1.1e-146 | 471.28 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-297/297 Sequence Identity: 39% (117 aa) YTLGPVIGTGSYATVKLGVD-KVNNIKVAVKLYEKFKLF-DPQKKKN-----------VQREIQILQKLD---HSHCIKLFKTIDTPKH------INLVM |..|...|.||...|||... . ...|||.| ..|.|. ||..||| ..|||||...|. | . |||. .|.||.| |.||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYVGSSS--LHSYLKLHTGRK--LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQN--NVKIIDFGFSII-----IPPEKKLSIFCGTPSYM ||... . |. |.. | .|. .||.||.|.|.|.. ...|.||...||||||.||||||... |.||||||||.. ..|..||..|||.|.|| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEIVAK--KEYYGQPVDIWAAGILLYVMLCGTFPFR-------GIDDKTLFKEIQRGEAKFPP---HVSTGAKYLIQKILNTNNNERINATSILKDTWL ||||... |.|.|..||||..|..||.|.||..||. | |.. ........ ..|| ||| .. ||.|.|..| ..|... |... |. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 20819.AA | CAMK | 178-427 | 26 | 6.5e-125 | 404.67 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 178-427
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)
VIGTGSYATVKLGVDKVNN------------IKVAVKLYEKFKLFD-------------------------PQKKKNVQREIQILQK-------LDHSHC
..|.||...|||...| .. |||.| ..| || | |...|||.|||.|..| ||| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKLFKTID------------TPKH--------INLVM---EYVGSS----SLHSYLKLHTG-------------RKLPENEAKRIFKQLILGLEYLHSKN
|||. ... | .. . .|| ||. | .|.. |.. ....| ||.|.|.|.. ...|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VVHRDIKLENILLDKQ-----------------NNVKIIDFGFSIIIPP------------------------EKKLSIFCGTPSYMA-PEIVAK-----
.||||.|.||||||. ||.|||||||.....| .|.. |||||.||| ||.. .
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------KEYYGQPVDIWAAGILLYVMLCGTFPFRGI-------------DDKTLFKEIQRGEAKFPPH------------------------VSTGAK
|.|||...|.|..|..||.||||..||.| .|. ||. |..|. |||. ||. .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
YLIQKILNTNNNERINATSILKDTWL
||.|.|... ..|.... .|.. |.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 20819.AA | AMPK | 173-427 | 41 | 2.5e-101 | 301.57 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-254/254 Sequence Identity: 41% (107 aa) YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTI-DTPKHINLVMEYVGSSSLHSYLKLHTGRKLP | .| ||.|.. ||.|. . . |||.| .| |. | . .. .||||.||... | | |.|. | .||. | .||||| | .| | ..|. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ ENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAAGILLYVMLCGTF | ||.| |.| | |.||.| ..|||| |.||.|||...|.|| ||| | . ..|. || | | |||... | | | |||| |. ||.||||. EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL PFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL || . ||.| | || . | ..|. ||.||...|... ..||. | .. |. PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 20819.AA | S_TKc | 173-427 | 32 | 5.3e-95 | 322.85 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-231/231 Sequence Identity: 32% (87 aa) YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGS--SSLHSYLKLHTGRK- |... .|| |....|.....| . .||.| ....||||||.| .| . .||. .... .|. .||||.. .|..|.| . ... YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQ-PVDIWAAGILLYV .|| .|.....|....|||.||....|||.| ||||||. ..||.|||.. .. . ||||| |||||.. || ..|.|. |..|| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE MLCGTFPFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILK-------DTWL |||| ||. .....|| | | || .|.|.|. . ..|. | .|. . |. MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 20819.AA | Pkinase | 173-427 | 30 | 1.4e-93 | 322.02 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-293/293 Sequence Identity: 30% (89 aa) YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQ-REIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGSS----SLHSYLKLHTG |..| .|| ||...|.....| ....|||| .| . . ... .. .||||...|.| . ..|. . ...|| .||||.. .|..|.. . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RKL--PENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNV----KIIDFGFSII--IPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAA ... .|.|.|....|.. ||||.||....|||.|.||||.|..... ||.|||.. . . .. ||||| |||||.. . .|||..||.|.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GILLYVMLCGTFPFRGI------DDKTLFKEIQRGEAKFPPHVS---------------------TGAKYLIQKILNTNNNERINATSILKDTWL |..|| |||| .||.| |.. ....| ... .|. . .| .| ..|. . ..|..|. ||.. |. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 20819.AA | TSSK | 173-427 | 31 | 2e-79 | 260.34 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-289/289 Sequence Identity: 31% (92 aa) YTLGPVIGTGSYATVKLGVDKVNNIK----------------VAVKLYEKFKLFDPQKKKNVQREIQILQK-LDHSHCIKLFKTIDTPK-HINLVMEYVG |..| .||.||||.|.....| ...| ||.| . | . ..| |||||. | |.|.. |... ...| .| .|||| YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE SSSLHSYLKLH---TGRK-LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEK------KLSIFCGTPSYMAPEIV . | .| . . .. . |.| .|.. |.|.. ...|.||.||||||.|.|||||||..|.|..||||. . |. . ... ||| .| ||||. HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL AKKEYYGQPVDIWAAGILLYVMLCGTFPFRG--IDDKTLFKEIQRGEAKFP----PHVSTGAKYLIQKILNTNNNERINATSILKDTWL ..| . .|.|. |. ||.|.||. || . ... ...| ...|| ...|. .| || ..| . ..|.... |... |. RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | 20819.AA | Ciliate-E2 | 173-427 | 25 | 3.9e-79 | 269.22 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 173-427
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)
YTLGPVIGTGSYATVKLGVD-----------------------KVNNIKVAVKLYEKFKLFDPQKKKNVQREIQ----------ILQKLDHSHCIKLFKT
| . .||.|....|... . ||.. ..|.| ..| ... ..... |||. ||..|.| . ||.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
ID--TPKHINLVMEYVGSSSLHSYLKLH----------TGRKLPENEAKRIFKQLIL---------------GLEYLHSKN-VVHRDIKLENILLDKQNN
. ..| |||||. .| .|.| . .. |.|.|.|.||.. .|||||||| ..|||||.||||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----
VKIIDFGFSIIIPPE------KKLSI--------------------------FCGTPSYMAPEIVAKKEY--------YGQPVDIWAAGILLYVMLCGTF
.||||||.| .. .. |... .|||| ||||||. .|.| |. .|||..|..|| ||.| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP
PFRGIDDKTLFKEIQRGEAKFP------------------PHVSTGAKYLIQK----ILNTNNNERIN-ATSILKDTWL
|| ...|. .. .|| ..| .| ||.| .|. . ..||. . ||. |.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 20819.AA | Ciliate-E2-Unclassified | 173-427 | 26 | 2.2e-78 | 266.73 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 173-427
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)
YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNV--------QREIQ--------------ILQKLDHSHCIKLFKTIDTPKHINLVM
|... .||.|....|.. ..| .. . | | |.. .. ....|. . ... ||. ..| . .|.| . . ..| .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYVGSSSLHSYLKL---------------HTGRKLPENEAK-----RIFKQLILGLEYLHSKN-VVHRDIKLENILLDKQN---NVKIIDFGFSII----
||. .|. |.| .......|..|| ..|.|...||||||.|| ..|||||.||||.|... ..||||||.|.
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
------------IPPEKKLSIFCGTPSYM----APEIVAKKEYYG---QPVDIWAAGILLYVMLCGTFPFRGIDDKT----------------LFKEIQR
|....... |||||.|| |||. ...|.. .|||. |..|| || |..|| . ... |...|.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
GEAKFPP--------HVSTGAKYLIQ----KILNTNNNERINATSILKDTWL
.. .||. |.| || .|. |.|. | |.||.. ||. |.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 20819.AA | QIK | 173-427 | 35 | 1.8e-77 | 263.66 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 173-427
Range on HMM: 1-272/272
Sequence Identity: 35% (98 aa)
YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGSSSLHSYLKLHTGR----
|... || | .|.|||. .. |||.| | .| | . . . ||.||. |.| | |||. . | . . .|.|| . . || | ||
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKH-GRKGVK
---------------KLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQP
..||||.|.|.|.... .|.|..|.||||.| ||||||.. |.||.||||| ... |. .||.| | |||. ||| |
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK
VDIWAAGILLYVMLCGTFPFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL
|||| |..|||. || .|| | ...| . . | . |. .|.. || . | . . |.. |.. |.
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | 20819.AA | ULK | 173-427 | 27 | 3.2e-69 | 236.29 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 173-427 Range on HMM: 1-329/329 Sequence Identity: 27% (91 aa) YTLGPVIGTGSYATVKLGVDKVN----NIKVAVKLYEKFK-LFDPQK------KKNVQREIQILQKLD--------HSHCIKLFKTIDTP--KHINLVME | | ..| ||...| | .| . |.|||.| .|.| ... .. ...||.|..||. | ...||.. |. ..| ..|| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YVGSSSLHSYLKLH--------TGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNN------------VKIIDFGFSIIIPPE----- | | .|.| . ....|.|.||. .|||.. |. .||..|..|||||..|||... . .|| ||||. . . YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ -KKLSI----FCGTPSYMAPEIVA----KKEYYGQPVDIWAAGILLYVMLCGTFPFRGIDDKTLF-----KE----------IQRGEAKFP-----PHVS . .|||| ||||.|. .|.|| .||| |...| || | ||.. ... |. |. .|| |..| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS TGAKYLIQKILNTNNNERINATSILKDTWL | ||.. | . ..||. . ... |. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 20819.AA | CAMK1 | 272-427 | 35 | 6.2e-61 | 175.84 | In-house | 107-276 (276) | Show / Hide |
Range on Protein: 272-427 Range on HMM: 107-276/276 Sequence Identity: 35% (61 aa) ENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILL-DKQNN--VK--IIDFGFSIIIPPEK-KLSIFCGTPSYMAPEIVAKK--EYYGQPVDIWAAGILL |..| .| ||.. .||.|||..||||.| ||.|. || .. .| |.||| | |. .. ... ||||.|.|||... | . |....|.| .|. . EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVIT YVMLCGTFPFRGID-DKTLFKEIQRGEAKFPPH----VSTG-AKYLIQKILNTNNNERINATSILKDTWL |..||| || . . |..||. | ..| || .| . || .| . |. . ..|.... .|.. |. YILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 20819.AA | CAMK1 | 173-253 | 30 | 3.1e-23 | 64.34 | In-house | 1-90 (276) | Show / Hide |
Range on Protein: 173-253 Range on HMM: 1-90/276 Sequence Identity: 30% (28 aa) YTLGPVIGTGSYATVKLGVDKVN---NIKVAVKLYEKFKLFDPQKK----KNVQREIQILQK---LDHSHCIKLFKTIDTPKHINLVMEYV | .| .||.|. ..|.|...| . . ..|.| .| | | .|. .....||.|..| .|| ..||.. ....|. ||||.| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELV |
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| Kinase | 20819.AA | Pkinase_Tyr | 173-318 | 31 | 1.1e-18 | 63.87 | Pfam | 1-156 (270) | Show / Hide |
Range on Protein: 173-318 Range on HMM: 1-156/270 Sequence Identity: 31% (50 aa) YTLGPVIGTGSYATVKLGVDK----VNNIKVAVKLYEKFKLFDPQK--KKNVQREIQILQKL-DHSHCIKL--FKT-IDTPKHINLVMEYVGSSSLHSYL |.| ..| |.. .|..|. | ..|.|||| ... .. ||..|. .| .| . ..| | . |..| .||||. .|..|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL KLH--TGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFG . | ...|. . . | |.|||.||| .|||. |.|....| ||| ||| RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG |
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| Kinase | 20819.AA | TyrKc | 173-425 | 23 | 7.2e-17 | 50.07 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 173-425 Range on HMM: 1-280/280 Sequence Identity: 23% (67 aa) YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKL--DHSHCIKLFKTIDTP-------KHINLVMEYVGSSSLHSYLK ||| ..| | . .| .|. | |.|||| . . .. ||..|. || .| . ..|. . .. . . .||||. .|..||. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR LHTGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPE-----KKLSIFC----GTPS-----YMAPEIVAKKEY | .. |. . . | | |||||||..|||. |.|..... ||| ||| | | . | . |. . |||| .... KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF YGQPVDIWAAGILLY-VMLCGTFPFRG-----IDDKTLFKEIQRGEAKFPPHV---------STGAKYLIQKILNTNNNERINATSILKDT . |.|. |.... .. | | | .... ... ...|. .|. .. .... . . ..| . . | .. TTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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