11795

Species: Tetrahymena
Alias: PreTt11795, 1.m00843, 933, 11795, TTHERM_00011890
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
11795.AA Protein None 837 None Fasta, JSON
11795.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
11795.NA RNA None 2514 None Fasta, JSON

Protein domain

Protein domains of 11795.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11795.AA MARK 581-834 50 7.1e-159 522.79 In-house 1-262 (262) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-262/262
Sequence Identity: 50% (132 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVKREISILKRLSHPNIIKMPYAFQ--DKNT-IVLVMECLSKLSLHSYLKKRVDRR
...  ..|.|.||.||||..|..|. .|.|||.|| |.||..|.||.|||.|.|.|.||||||......  .... |.|.||. |. .|..|.|.....|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

VSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNK-NIKIIDFGFSICS--AVKLKIFCGTPTYMAPEIVSKVDYCGKKADIWALGIVLYVLL
 .|.||. .|.|.||.. |||..|| |||||.||||.||... ||||||||||||     ||..||||| ||||||..| .|.|.|.|||.||.|||...
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGKFPFRGMS--DNELFKKIRNCVYDPPNHVSEKCLNLLKKLLKFNPSDRPDCYEILQDSWF
||.|||.| .  ..||.|||....|| | ||| .| ||...||..||..||.. ||....|.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 11795.AA CAMKL 581-834 38 4.5e-134 430.33 In-house 1-297 (297) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-297/297
Sequence Identity: 38% (116 aa)

FRLEGELGKGAYATVKLAVD-KNSGETYALKIYQKFTLT-DPNKMRN-----------VKREISILKRLS---HPNIIKMPYAFQDKNT------IVLVM
.|.. .||||....||||.. .. || .| ||. |. .. ||....|           ..|||.|.|.|.   ||||||.   ......      |.|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ECLSKLS--LHSYLKKRVDRR--VSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNK-NIKIIDFGFS---I-C---SAVKLKIFCGTPTYM
|  |  .  |. |..|. .||   .|.||. .| |.||...||| ..| |||||.||||.||... ||||||||||   . |   .  |||.|||.| ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIVSK--VDYCGKKADIWALGIVLYVLLCGKFPFR-------GMSDNELFKKIRNC-VYD-PPNHVSEKCLNLLKKLLKFNPSDRPDCYEILQDSWF
||||...   .|.|.|.|||..|..||...||..||.       |.... ..... .|  |. ...|||  | .|..|.|. ||..|| . .|... |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 11795.AA CAMK 586-834 26 6.8e-122 394.76 In-house 1-425 (425) Show / Hide
Range on Protein: 586-834
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)

ELGKGAYATVKLAVDKNSG------------ETYALKIYQKFTLTD-------------------------PNKMRNVKREISILKRLS-------HPNI
.||.|....|||...||..            . .| ||. |  |.|                         |....||.|||.|.|.|.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKMPYAFQD-------------------KNTIVLVM---ECLSKL----SLHSYLKKRVD-------------RRVSESEAKIMFHQLVSGIDYCHMRNI
||.  ...|                   .. ...||   |  |       | .|.... .             .|..|.||. .|.|..|...||| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

EHRDIKLENILVDEQN----------------KNIKIIDFGFSICSAV--------------------------KLKIFCGTPTYMA-PEIVSK------
 |||.|.||||.|. |                 |||||||||..                              |.| ||||| ||| ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------VDYCGKKADIWALGIVLYVLLCGKFPFRGM-------------SDNELFKKIRNCVYD-PPNH---------------VSEK--------CLN
        .|.|.|.|.|..|..||..|||..||.|              .|.|||.||... || || .               .|.         | .
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLKKLLKFNPSDRPDCYEILQDSWF
|..|.|. .|..|. . ..|.. |.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 11795.AA AGC 581-834 23 3.4e-99 256.49 In-house 1-395 (395) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

FRLEGELGKGAYATVKLAVDK------NSGETYALKIYQKFT---LTDPNKMRNVKRE------------ISILKRLS----------HPNIIK-MPYAF
|..   .|||.. .| |. .|       .|. ||.|. .| .   ... |.......|              ||....          ||.|.| . |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDKNT--IVLVME----------CLSKLSLHSYLKKR-VDRRVSESEAKIMFHQ-------LVSGIDYCHM-RNIEHRD-IKLENILVDEQNKNIKIIDF
|||.   . .|||          |   . |...|..|   .| .|..|.... .       .|....| |  ..| ||| .|.|||| ||.  .||. ||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED-GHIKLTDF

GFS-----------------------------------------------------ICS-AVKLKIFCG--TPTYMAPEIVSKVDYCGKKADIWA--LGI
|..                                                     . .  .. . |||  || ||||||.     .|| .|.|.  ||.
GLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGC

VLYVLLCGKFPFRGMSDN----------ELFKKIR--------NCVYDPP--------NHVSEKCLNLLKKLLKFNPSDRPDC----------YEILQDS
..| .|.|. ||.| ...          |.|.||.        .  ...|         ..|. . .|.||||. .|..|. |           || .  
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

WF
||
WF

Kinase 11795.AA S_TKc 581-834 34 4.8e-97 329.62 SMART 1-231 (231) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVKREISILKRLSHPNIIKMPYAFQDKNTIVLVMECLSK--LSLHSYLKKRVDRR-
...  ..||||...|.....|..|. .|.||            ....|||.|||.  ||||.|. ..||| . . .|||...    .|..|.|||  .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNIKIIDFGFSICSAVKLKIFCGTPTYMAPEIVSKVDYCGK-KADIWALGIVLYVL
    .| .|. ...|......||| ..| |||.| ||||.||   .|||.|||..       . ||||| |||||..      || |.|.|..|..|| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

LCGKFPFRGMSDNELFKKIRNCVYDPPNHVSEKCLNLLKKLLKFNPSDRPDCYEILQ-------DSWF
|||. ||.   ....||||.          |. ......|.|...|..|| . |.||       . ||
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 11795.AA Pkinase 581-834 30 7e-90 309.7 Pfam 1-293 (293) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVK-REISILKRLSHPNIIKMPYAFQDKNTIVLVMECLSKL----SLHSYLKKRVD
..... .|.|....|.....|..|...|.||  | .  .  ...... .||.|.|||.||||... ..|.||. | .|||.. .     .|..|.. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRV--SESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNI----KIIDFGFS----ICSAVKLKIFCGTPTYMAPEIVSKVDYCGKKADIWA
...  || |.| .. |...|..||| ..| |||.|.||||.| .| .|    ||.|||..    . . . .. ||||| |||||.. .  | |.|.|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGIVLYVLLCGKFPFRGM------SDNELFKKIRNCVYDPPNHVS---------------------EKCLNLLKKLLKFNPSDRPDCYEILQDSWF
.|..|| .|||..||.|       ........|. . .. .   .                     | |. ..|..|...|..|| . .|||. ||
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 11795.AA AMPK 581-834 38 1.2e-84 251.22 In-house 1-254 (254) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-254/254
Sequence Identity: 38% (99 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVKREISILKRLSHPNIIKMPYAF-QDKNTIVLVMECLSKLSLHSYLKKRVDRRVS
. ..  .|.|..  ||... .  ||  |.||  |  ..|   .  ..|||.||| . ||.||.        .  | .|||  |   | .|  |.  .|..
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ

ESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNIKIIDFGFS--ICSAVKLKIFCGTPTYMAPEIVSKVDYCGKKADIWALGIVLYVLLCGK
| ||.  | | .||..|||  .| ||| |.||.| | .|||||| ||| |     . .||  || | | |||..|   ||| . |||  |..||..|||.
EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD-HNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY

FPFRGMSDNELFKKIRNCVYDPPNHVSEKCLNLLKKLLKFNPSDRPDCYEILQDSWF
 ||   .  .|.|||.|..|  | ..|... .|.|..|. .|  | .  .| ...||
LPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 11795.AA Ciliate-E2 581-834 25 3.6e-81 275.99 In-house 1-365 (365) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-365/365
Sequence Identity: 25% (98 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDP-------------------NKMRNVKREISILK----------------RLSHPNIIKMP
. .   .|.|....|... ... .. .|.|| . . .  .                   |. ...|.||.|..                .|.||||||| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

YAFQ--DKNTIVLVMECLSKLSLHSYLKKR----------VDRRVSESEAKIMFHQLVS---------------GIDYCHMRN-IEHRDIKLENILVDEQ
..||  |.|.| |||| ..  .| .|.|..             . .| |.| .. |...               .. |.| .| | |||||.||||.   
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

NKNIKIIDFGFSI-----------CSAVKLKIF-----------------------CGTPTYMAPEIVSKVDY--------CGKKADIWALGIVLYVLLC
   |||||||.|            ..  |...|                       |||| ||||||... .|         ..|.|||.||..|| .|.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GKFPFRGMSDNELFKKIRNCVYDPP------------------NHVSEKCLNLLKK----LLKFNPSDRPD-CYEILQDSWF
||.||        ...| .| .| |                  ...|..| .|.||    .|. .|. |..   .||.  ||
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 11795.AA Ciliate-E2-Unclassified 581-834 27 3.9e-76 259.25 In-house 1-352 (352) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNV---KREISILKRLS-------------------HPNIIKMPYAFQDKNTIVLVM
...   .|.|....|.....|. .. ||.|.  |.   . ....|.   ..|. ......                   ||.|.|| |.||||..| .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ECLSKLSLHSYLKKRVD---------------RRVSESEAK-----IMFHQLVSGIDYCHMRN-IEHRDIKLENILVDEQNK--NIKIIDFGFSICSAVK
| .  ..|. |.|||                 ....| .||      .| |...|..|.|  | | |||||.||||.|...|  .|||||||.|. .   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------------LKIFCGTPTYM----APEIVSKVDYCG---KKADIWALGIVLYVLLCGKFPFRGMSDNE----------------LFKKIRN
                  .. ||||| ||    |||.  .  | .   .|.|||.||..|| .| |..|| . ....                |...| .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

CVYDPPN--------HVSEKCLNLLK----KLLKFNPSDRPDCYEILQDSWF
. .. |.        |.|... ....    |.|| ||. |..  .||.  ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 11795.AA ULK 581-834 28 1.2e-71 244.34 In-house 1-324 (324) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-324/324
Sequence Identity: 28% (91 aa)

FRLEGELGKGAYA-TVKLAVDKNS---GETYALKIYQKFTLTDPNKMR-------NVKREISILKRLS---HPN--IIKMPYAFQDK--NTIVLVMECLS
. |  .||||... .|  . .|..   .. .| |. .|. . . ....       . |.||.|.| |    |||  |.|.   |...  | | ..||   
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

KLSLHSYLKKRVD-------RRVSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDE-QNKN----------IKIIDFGFSIC------SAVKLKI
   | .|.||.         .| ||.||.. |.|...|  . | .|| |||||..|||. . | |.          .|| ||||.        .. ... 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GTPTYMAPEIVS----KVDYCGKKADIWALGIVLYVLLCGKFPFRGMSDNELF----------------KKIRNCVYDPPN---HVSEKCLN
..      ||| ||||.|..    . .|. .|.||| ||...| .| || ||...  |...                 | ..  ...|.   ..|..| .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LLKKLLKFNPSDRPDCYEILQDSWF
|....|.....|| .  ||..  ||
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 11795.AA ULK 581-834 28 4.9e-71 242.3 In-house 1-329 (329) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

FRLEGELGKGAYATVKLAVDKNS----GETYALKIYQKFTLTDPNKMRN-------VKREISILKRLS--------HPNIIKMPYAFQDK--NTIVLVME
. |  .||||....|  . .|..    .| .| |. .|...   |....       .|.|| |.|.|         ||||.|.   |...  | | ..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

CLSKLSLHSYLKKRVD--------RRVSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDE-QNKN----------IKIIDFGFSIC---S-----
      | .|.||.          .| ||.||.. |.|...|  . | .|| |||||..|||... | |.          .|| ||||.     .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AVKLKI----FCGTPTYMAPEIVS----KVDYCGKKADIWALGIVLYVLLCGKFPFRGMSDNELF-----KKIRN------------CVYDPP---NHVS
  .       .|||| ||||.|..    . .|. .|.||| ||...| .| || ||...  |...     | |.|              ....   ...|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EKCLNLLKKLLKFNPSDRPDCYEILQDSWF
..| .|....|.....|| .  |...  ||
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 11795.AA QIK 581-834 36 1e-68 234.61 In-house 1-272 (272) Show / Hide
Range on Protein: 581-834
Range on HMM: 1-272/272
Sequence Identity: 36% (99 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVKREISILKRLSHPNIIKMPYAFQDKNTIVLVMECLSKLSLHSYLKK--R-----
. .|  .||| .|.||||  ..  .  | ||  |  |.  | .  ..||. |.|.|.||.|||       .. . .|.|  |   .  || |  |     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEEN-LQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

-----------VDRRVSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNIKIIDFGFS--ICSAVKLKIFCGTPTYMAPEIVSKVDYCGKK
           .   ..|.||. .| |..|...||| ||| |||.| |||| | .| ||||.|||||    .   |. .||.| | |||.    .| | |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLD-NNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADIWALGIVLYVLLCGKFPFRGMSDNELFKKIRNCVYDPPNHVSEKCLNLLKKLLKFNPSDRPDCYEILQDSWF
.||| .|.||||| ||..|| | ....| ...    .  |  .|. |  | .. |  .|. |     |.|  | 
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 11795.AA TyrKc 581-829 22 2.1e-16 42.42 SMART 1-280 (280) Show / Hide
Range on Protein: 581-829
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FRLEGELGKGAYATVKLAVDKNSGETYALKIYQKFTLTDPNKMRNVKREISILKRL--SHPNIIKMPYAFQDK-------NTIVLVMECLSKLSLHSYLK
 .|. .|| ||. .| ... |   .. | |  .. .      ..   ||..|...|  .||||...  .  ..         . .|||  .. .|..||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRVDRRVSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNIKIIDFGFSICSAVK-------LKIFC----GTPT-----YMAPEIVSKVD
|. .. .. ..   . .|  .| .| | .|. |||.   |.||.|..  .|| ||| |     .         .      |. |      ||||     .
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NY

Y-CGKKADIWALGIVLY-VLLCGKFPFRG-----MSDNELFKKIRNC-VYDPPNH--------VSEKCLNLLKKLLKFNPSDRP---DCYEIL
. .  | |.|. |.... ..  |. |  |     ||. |.......    ..| .         ...  .. |.  ...|.|||   ...|..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 11795.AA Pkinase_Tyr 581-727 28 3.6e-10 35.06 Pfam 1-156 (270) Show / Hide
Range on Protein: 581-727
Range on HMM: 1-156/270
Sequence Identity: 28% (45 aa)

FRLEGELGKGAYATVKLAVDK----NSGETYALKIYQKFTLTDPN-KMRNVKREISILKRL-SHPNIIKMPYAFQ-DKNT--IVLVMECLSKLSLHSYLK
 ..  .||.||. .|.... |    | . . | |.  | . .... ...   ||..|.| | .||||...  .   ..    | .|||   . .|..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KR--VDRRVSESEAKIMFHQLVSGIDYCHMRNIEHRDIKLENILVDEQNKNIKIIDFG
|.   ..... ..   | .|  .| .| . .|. |||.   |.||.|.|  .|| |||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFG

Kinase 11795.AA Pkinase_Tyr 760-794 28 0.000796 13.58 Pfam 194-231 (270) Show / Hide
Range on Protein: 760-794
Range on HMM: 194-231/270
Sequence Identity: 28% (11 aa)

KADIWALGIVLYVLLC-GKFP-FRGMSDNELFKKI-RN
| |.|. |.... ..  |. | . |||..|....| ..
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED