Gene 5359 (Tetrahymena)

5359

Species: Tetrahymena
Alias: 5359, 36.m00323, TTHERM_00353450, PreTt05359, 3703.m00182, 479
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
5359.AA Protein None 467 None Fasta, JSON
5359.kin_dom Protein Kinase Domain None 261 None Fasta, JSON
5359.NA RNA None 1404 None Fasta, JSON

Protein domain

Protein domains of 5359.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5359.AA CAMKL-Unclassified 97-357 61 5e-206 690.75 In-house 1-290 (290) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-290/290
Sequence Identity: 61% (179 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVFIMEYLEGGELLDRVDKVGHFTEE
||.|.|.||||||||||..||.||||.|||.|||...|.|.|||||||||||||||||||||||||||||||||||.|||||.||||||...|.|||.|.
YNIVQVIGEGGFGQVQLAEHKQTQEKFAIKFVKTMNHGCAMDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVMIMEYLQGGELLDWCRKNGHFNEN

QAK-------VYFKQIVDAMNYCHKNKLIHRDLKLENLLLV-SESSDQIKVVDFGIAGVASK-QSVENIDAGSLRYMAPEVLNGKTKQITPAIDVWAMGV
.|.       .||.||||||.|||||..|||||||||.||. ..||..||..||||||||.. |.|.||..|||||||||..|...|||...||.|||||
NARRQPWEIQQYFQQIVDAMQYCHKNCIIHRDLKLENVLLRQQDSSPVIKIFDFGIAGVANVNQNVFNINGGSLRYMAPEMKNQQVKQIQYSIDIWAMGV

ILYMMIVGEFPFNG---------------PNNNVIMEKITEGVYEIPKDIKKKLSKECLD-----VIEKTLQVDPANRISTVDLMNHPFI
.|||.||..|||||               .|||.||.|||.|.||.|..|.|.|..||.|     .||...||.|.||..|...|.||..
MLYMCIVQFFPFNGNGNNGKNNNSDGNENDNNNNIMFKITRGPYEFPEQINKPLPDECKDQRLISLIENIFQVNPKNRFTTHQIMQHPWM
Kinase 5359.AA CAMKL 97-357 34 2.7e-114 366.17 In-house 1-297 (297) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-297/297
Sequence Identity: 34% (103 aa)

YNLVKVLGEGGFGQVQLGLH-KITQEKVAIKIVKTNIIGNASDIDM------------VFREAEILKSLN---HKNIVKIKNCYTLSDM-----KVVFIM
|...|.||.|.||.|.|..| ..|.|||||||.. . | |   ...            ..||..|.|.||   |.||.|.  ... ...     |.. .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLEGGE--LLDRVDKVGH----FTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVASK-----QSVENIDAGSLRYM
|| .|||  |.|...| ||    ..|..|. ||.|||.|.||||... .|||.|.||.|| .  . .||..||| .    .         ..  ||. ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLNG-KTKQITPAIDVWAMGVILYMMIVGEFPFNGPNN------NVIMEKITEGVYEIPKDIKKKLSKECLDVIEKTLQVDPANRISTVDLMNHPFI
|||...| ... . |..|.|..|||||.|..|..||.....      |.  ..  . .     .| ...| .| | | | |||.|  |..  ..||||. 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 5359.AA CAMK 102-357 26 1.8e-106 344.21 In-house 1-425 (425) Show / Hide 
Range on Protein: 102-357
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)

VLGEGGFGQVQLGLHKITQ------------EKVAIKIVKTNIIGN-------------------------ASDIDMVFREAEILKS-------LNHKNI
.||.|.||.| |. || |.            .||||||.... . .                         ..| ..|.|| ||.|.       |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKIKNCYT------------LSDM-------KVVFIM---EYLEGGEL----LDRVDKVGH---------------FTEEQAKVYFKQIVDAMNYCHKNK
.|.   |               ..       .....|   || .||||    .|.. . |.               |||..|. ||.||..|..|||...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

LIHRDLKLENLLLVSESSD---------------QIKVVDFGIAGVASKQSVEN------------------------IDAGSLRYMA-PEVLNGK----
 .|||||.||.||.. ..|               .||..||| | .  . . ..                           |.. ||| |||||||    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------TKQITPAIDVWAMGVILYMMIVGEFPFNGP-------------NNNVIMEKITEGVYE-IPKDIKK-------------------KLSKECL
         . ..|..|.|..|||||.| .|..||.|.             | . ..|||..| |. .|. ...                   ..|.|| 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DVIEKTLQVDPANRISTVDLMNHPFI
| | | ||||| .|..  . .|||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 5359.AA S_TKc 97-357 33 1e-95 325.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVFIMEYLEG--GELLDRVDKVGH--
| .....|.|.||.| .. || |...|||||.|          ... || .|||. .|.||||.. ..     .. ..|||..|  |.|.|. .| |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVASKQSVENIDAGSLRYMAPEVLNGKTKQITP-AIDVWAMGV
    |.| .|. |..||..|..|||... |||||| ||.|| .    .||. |||.| .       .   |.. |||||||     . .. ..|.|. |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGC

ILYMMIVGEFPFNGPNNNVIMEKITEGVYEIPKDIKKKLSKECLDVIEKTLQVDPANRISTVDLMN-------HPFI
||| |..|. ||   . .....||               |.|..| |.| ||.||..|..  ....       ||..
ILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 5359.AA AGC 97-357 23 1.9e-88 228.03 In-house 1-395 (395) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-395/395
Sequence Identity: 23% (95 aa)

YNLVKVLGEGGFGQVQLGLHK------ITQEKVAIKIVK-TN-IIGNAS-DIDMVFRE------------AEILKSLN----------HKNIVK-IKNCY
....||.|.|.||.| |  .|       |..  |.|..|    |. .   ..... .|             .||. .|          | .|||  . ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TLSDM-KVVFIMEYLE---------GG-ELLDRV--D-KVGHFTEEQAKVYFKQ-------IVDAMNYCHK-NKLIHRD-LKLENLLLVSESSDQIKVVD
   |  .. |.|||..         || ||. .   . | |.|.||.|. |. .       || |. | |. .. |||| ||.||.|| ..    || .|
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED--GHIKLTD

FGIAGVAS---------------------------------------------------KQSVENIDAG--SLRYMAPEVLNGKTKQITPAIDVWA--MG
|| . .                                                     |.   .   |  .  |||||.|       ..| | |.  .|
FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLG

VILYMMIVGEFPFNGPNNN----------VIMEKITEGVYEIPKDIK------------KKLSKECLDVIEKTLQVDPANRIS----------TVDLMNH
...| |..|  ||.| |..           ...|| .| |.|....|            ...|.|. | |.| |..||..|.           . ...||
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

PFI
|. 
PWF
Kinase 5359.AA Ciliate-E2 97-357 25 6.2e-88 298.44 In-house 1-365 (365) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YNLVKVLGEGGFGQVQLGLHKITQEK-----------------------VAIKIVKTNIIGNASDIDMVFREAE----------ILKSLNHKNIVKIKNC
|...|..|.|.||.| .. .. .|..                       .|.||.| | | . . .. ..|| .          ||..|||.||.|.. |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YTL-SDMKVVFIMEYLEGGELLDRVDKV-----------GHFTEEQAKVYFKQIVD---------------AMNYCHKNK-LIHRDLKLENLLLVSESSD
.   .| .. ..|||..||.|.|.  .            . |||...| ..|||..               |..|.|...  ||||.|.||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

QIKVVDFGIAGVASKQSVENID--------------------------------AGSLRYMAPEVLNGKT-------KQITPAIDVWAMGVILYMMIVGE
 ||..|||..  ..... ....                                .|.. |||||.||||        |. . ..|.|..|||||.|. |.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPFNGPNNNVIMEKITEGVYEIPKD--------------IKKKLSKECLDVIEK----TLQVDPANRIS-TVDLMNHPFI
.||        ...| .. ...|.               ..||.|.|| | | |     ||.|| .||.   ...|||..
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 5359.AA MARK 97-357 36 2.6e-83 272.2 In-house 1-262 (262) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-262/262
Sequence Identity: 36% (99 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFREAEILKSLNHKNIVKIKNCYTLS--DMK--VVFIMEYLEGGELLDRVDKV--
| ..|..|.|....| |..|| |..||||||.. . .     . .|.||.||.|.|.|.||.|    ..    . .  ...|||| .||||.|.. ..  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKL--FHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

GHFTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVASKQSVENIDAGSLRYMAPEVLNGKTKQITPAIDVWAMGVILY
|. .|| |...|.||| |.||||..  .|||.|.||.|. ..   .||  ||| .      .  |.  |.. |||||....| .   |..|.|..||.||
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKK-PYDGPKVDIWSLGVVLY

MMIVGEFPFNGPN--NNVIMEKITEGVYEIPKDIKKKLSKECLDVIEKTLQVDPANRISTVDLMNHPFI
 |..| ||| | .  .. ...||. |.|.||      .|||| . | . |.|.|  |..  ..|.||..
FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 5359.AA Pkinase 97-357 30 1.6e-82 285.28 Pfam 1-293 (293) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFR---EAEILKSLNHKNIVKIKNCYTLSDMKVVFIMEYLEGG----ELLDRVD-
| .....|.|.||.| .. || |...||.||.|    .. |. |.  |   |..|.|.|||.|||... ...  . .. ..|||.|||    .| |..  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST

-KVGHF--TEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQI----KVVDFGIAGV--ASKQSVENIDAGSLRYMAPEVLNGKTKQITPA
 . | |  .|...| |..||. ...|||... ||||||.||.|..  . ..|    |. |||.| .    ..|  .  .|...||||||.. . . ..|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPK

IDVWAMGVILYMMIVGEFPFNGP------NNNVIMEKITEGVYEIPKDIKKKLS-----------------KECLDVIEKTLQVDPANRISTVDLMNHPF
.|.|..|.||| |. |..|| |       . ......| .. .. . . .   |                 .||.|.|.. |..||. |..  ....||.
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

I
.
F
Kinase 5359.AA Ciliate-E2-Unclassified 97-357 25 5.8e-79 268.64 In-house 1-352 (352) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGN-----ASDIDMVFREAEILKS----------------LNHKNIVKIKNCYTL-SDMKVVFI
|...|..|.||||.|..  || .... |.|. | ..| .      .| .... . |. .                 |||......| .|.  .. .. ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYLEGGELLDRVDKVGH-----------------FTEEQAK-----VYFKQIVDAMNYCHKNK-LIHRDLKLENLLLVSESS-DQIKVVDFGIA-GVAS
|||.|||.|..   | ..                 |||.|||      ||.||... .|.|...  ||||.|.||.|. .. .  .||. ||||.    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

KQSVENID----------------AGSLRYM----APEVLNGKTKQIT--PAIDVWAMGVILYMMIVGEFPFNGPNNNV----------------IMEKI
 .  .  .                .|...||    ||||| |.    .   ..|.|..||||| |. |..||...| .                 . ..|
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TEGVYEIPKDIK----KKLSKECLDVIE----KTLQVDPANRISTVDLMNHPFI
 .. ...||  .    |..|.|. | |.    | |...| .||.  ...|||..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 5359.AA AMPK 97-357 39 1.1e-77 230.23 In-house 1-254 (254) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-254/254
Sequence Identity: 39% (104 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVFIMEYLEGGELLDRVDKVGHFTEE
| . | .||| || | .| |..|.|||||||     | . ..   . || .|||...| .|..       .      .|||  |||| | . | |  .|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVASKQSVENIDAGSLRYMAPEVLNGKTKQITPAIDVWAMGVILYMMIVGE
.|. .|.||. .  |||...  |||||.|||||      .||.||||   . ..        ||  | |||.  || .   | .|.|  ||||| |. | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD--HNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGK-LYCGPEVDIWSCGVILYAMLCGY

FPFNGPNNNVIMEKITEGVYEIPKDIKKKLSKECLDVIEKTLQVDPANRISTVDLMNHPFI
 ||  .|  .   ||..|.|.|||.    ||.|. | |.. ||||| .||.  |..|||. 
LPFDDENTPTLYKKIKNGEYYIPKF----LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 5359.AA ULK 97-357 28 3e-68 233.05 In-house 1-324 (324) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-324/324
Sequence Identity: 28% (91 aa)

YNLVKVLGEGGFG-QVQLGLHKIT---QEKVAIKIVK-TNIIGNASD------IDMVFREAEILKSLN---HKN--IVKIKNCYTLSDM-KVVFIMEYLE
|.| ..||.| || .|  | .|.|   ...||.|..   ... . ..      ...  .| .|.| |.   |.|  ||| . ..  |.   . .|||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGELLDRVDKVGH---------FTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSD----------QIKVVDFGIAGVASKQSVENIDA--
|| | .   | ..         ..|..|. .||||. .. . ||.. ||||.|..|.|.                ..|. ||| | .  . . |  .   
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSLRYMAPEVLNGK--TKQITPA-IDVWAMGVILYMMIVGEFP----FNGPNNNVIMEKITEG------VYEIPKDIKK-----KLSKECLD
        |.  ||||..|.|.   |. . .  |.| .|.|.| |. |. |    ||  ... |.. |  |      ..  | ...|     |.|.|| |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

VIEKTLQVDPANRISTVDLMNHPFI
 | . ||.|.  |||  .. |||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 5359.AA CDPK 173-272 40 1.8e-40 121.95 In-house 78-189 (271) Show / Hide 
Range on Protein: 173-272
Range on HMM: 78-189/271
Sequence Identity: 40% (45 aa)

FIME--YLEGGELLDRVDKVGHFTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSD-----QIKVVDFGIAGVASKQ-----SVENIDAGS
..||  |..||||.|..   ||||| .|  ...||. | ||||.|. .||||| ||.|. | ..|     .|||.|.|..    ..      . .  .| 
IVMETEYCTGGELFDYIIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGT

LRYMAPEVLNGK
  |.|||||..|
PYYIAPEVLQKK
Kinase 5359.AA CDPK 281-357 38 7.3e-24 70.26 In-house 195-271 (271) Show / Hide 
Range on Protein: 281-357
Range on HMM: 195-271/271
Sequence Identity: 38% (30 aa)

DVWAMGVILYMMIVGEFPFNGPNNNVIMEKITEGVYEIPKDIKKKLSKECLDVIEKTLQVDPANRISTVDLMNHPFI
|.|  ||||| ...|. ||.| | . ||||. .|.|.  ..  .. |.|. | |.| |..|| .|.|  . ..|| .
DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 5359.AA Pkinase_Tyr 97-290 29 1.3e-20 70.47 Pfam 1-205 (270) Show / Hide 
Range on Protein: 97-290
Range on HMM: 1-205/270
Sequence Identity: 29% (62 aa)

YNLVKVLGEGGFGQVQLGLHK----ITQEKVAIKIVKTNIIGNASD--IDMVFREAEILKSL-NHKNIVKIKNCYTLSDMK--VVFIMEYLEGGELLDRV
  . |.|||| ||.| .|  |     |. .||.|..|       ..  ... .|||.|.|.| .|.|||.   . |  .    .  .||| ..| |||  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

DK----VGHFTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVA---SKQ-SVENIDAGSLRYMAPEVLNGKTKQITPA
 |     ...| ..   .  || ..|.| . ...|||||   | |. .  . ..|. ||| |      .    .        . ||||..| .    | .
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK--FTTK

IDVWAMGVILY
 |||. || ..
SDVWSFGVLMW
Kinase 5359.AA TyrKc 97-357 24 1.1e-19 72.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 97-357
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

YNLVKVLGEGGFGQVQLGLHKITQEKVAIKIVKTNIIGNASDIDMVFREAEILKSL--NHKNIVKIKNCYTLS------DMKVVFIMEYLEGGELLDRVD
  | |.|||| ||.| .|  |   ..||.| .| .       . .  |||.|...|  .|.|||..  . | .      .  .  .||| ..| |.|.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KVGH-FTEEQAKVYFKQIVDAMNYCHKNKLIHRDLKLENLLLVSESSDQIKVVDFGIAGVASKQ-----SVENIDA-----GS----LRYMAPEVLNGKT
| .. .. ..   .  || . |.| |....|||||   | |. ..   ..|. ||| .           | . ...     |     .| ||||..  ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NY

KQITPAIDVWAMGVILY-MMIVGEFPFNG-----PNNNVIMEKITEG-VYEIPKDIKKK-----LSKECLDVIEKTLQVDPANRISTVDLMNHPFI
.  |.. |||. || .. ..  |. |  |      .|  ..|.. .|   ..|...         ..|  .....  . ||..| .  ..  | ..
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 5359.AA CDPK 97-160 46 1e-18 54.26 In-house 1-66 (271) Show / Hide 
Range on Protein: 97-160
Range on HMM: 1-66/271
Sequence Identity: 46% (31 aa)

YNLVKVLGEGGFGQVQLGLHK-IT-QEKVAIKIVKTNIIGNASDIDMVFREAEILKSLNHKNIVKI
| . ||||.|.|||| .. || .| ||.||.||.. . . .. .....|.| ||||.| | ||.||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKI