13265

Species: Tetrahymena
Alias: PreTt13265, 3707.m00299, 445, 4.m00664, 13265, TTHERM_00070750
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
13265.AA Protein None 529 None Fasta, JSON
13265.kin_dom Protein Kinase Domain None 263 None Fasta, JSON
13265.NA RNA None 1590 None Fasta, JSON

Protein domain

Protein domains of 13265.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13265.AA CAMK1 77-339 45 7.2e-181 530.56 In-house 1-276 (276) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-276/276
Sequence Identity: 45% (127 aa)

YENIKILGKGTFAKVFLTKMVR---GGQEFAVKTFD-KRALLTSKNSEKTRTGLLNEIQILRKC---DHPNIIKLYEVYESDNYIYLVQNVLKGGELFDT
||..|..|.|.|..|.| .. .   .|...|.| .| |... ..... | .. |.|||.|..|.   |||||||.||.|||||..|||.. ..|||||| 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

IIKNGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIK--LADFGLAAFTSDD--LLFKRCGTPGYVAPEILED---KKYDQKVD
|...||..||.|..|..|.|||.||.|.|.|.|||.||||| ..||..|..||  .|||||. ....|  |....||||||||||.||.   | ||...|
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

VFSSGVILYILLTGCSPFYGKS-YNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF
..| |||.||||.|..|||... .||...|.|.|.. .. .. .  ..||| ...|.||.|||| |.|..|.||....
MWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase 13265.AA Ciliate-E2a 77-339 48 3e-148 439.47 In-house 1-275 (275) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-275/275
Sequence Identity: 48% (134 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKGGELFDTIIKNGNF
|. ||..|||.|..|.| .  . |..||.| |.|..  . |..|.    . |||.|.|. |||||||||||||..|..|||   ..||||.| |.....|
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEY----FMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRF

SEK--NAAKIIHQLLS-ALEYIHAKNIMHRDIKPENLILV--DKSDD--FQIKLADFGLAAFTSDDL---LFKRCGTPGYVAPEILEDKK------YDQK
 |.  ....|. |||. .|.|.| .||||||.||||...   .|...  ..||..||||| | ..|    .|..||||||||||.|  |       ||.|
FEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTK

VDVFSSGVILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF
.|..| |||.||||.|..||.||.||||| .||.|.|... .|   |.|.|.  |.||||..||| |||| ||||. .|
CDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 13265.AA CAMK 82-339 27 3.6e-119 385.83 In-house 1-425 (425) Show / Hide
Range on Protein: 82-339
Range on HMM: 1-425/425
Sequence Identity: 27% (116 aa)

ILGKGTFAKVFLTKMVRGG------------QEFAVKTFDKRALLTSKN---------------------SEKTRTGLLNEIQILRKC-------DHPNI
.||.|.|.||.| .  . .            |..|.|  ||. |  ..|                     ..|.|  ...||.|..|.       |||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYEVYES-------------------DNYIYLVQ---NVLKGGEL----FDTIIKNGN---------------FSEKNAAKIIHQLLSALEYIHAKNI
||||||||.                   |...|.|        ||||    || |...|.               |.|. |.....|..||..|.| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDIKPENLILVDKSDD--------------FQIKLADFGLAA-FTS------------------------DDLLFKRCGTPGYVA-PEILEDKK----
.|||.||||. |.|..||              ..||..|||.|. |..                        ....  .||||.|.| ||.|. |.    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDQKVDVFSSGVILYILLTGCSPFYGK-------------SYNEILSKNKNCQISYDFNELGV-------------------KVSQEATE
          |..|.|. | ||||||.|.|..||||.             ...|.. | .... ...  ..                     .||||.  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLKKMLDVDPKTRITASQALNDRFF
|..||| |||. |.|..|.||. ..
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 13265.AA CDPK 77-339 43 4.5e-111 341.87 In-house 1-271 (271) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-271/271
Sequence Identity: 43% (122 aa)

YENIKILGKGTFAKVFLTKMV-RGGQEF-AVKTFDKRALLTSKNSEK-TRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLV--QNVLKGGELFDTII
|   |.||||.|  |.. |.    .||  |.|.  |. .   |..|.  .  ..||| ||.. |||||||.||.|. ....|.|    ...|||||| ||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRV---KDKEQQQQ--FFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYII

KNGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDD----FQIKLADFGLA-AFTSD-----DLLFKRCGTPGYVAPEILEDKKYDQKV
 .|.|.|| ||.|. |.|||. |.| .||.|||.||||. .  |.||    ..||. |.|..  | ..     . . .||||| |.|||.|. | |..|.
EKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKC

DVFSSGVILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF
|. | |||||||| |  |||||. .||. | |... |..  |   ..|.||  | .||| .||| |..|.|||..  |
DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEW-DHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase 13265.AA S_TKc 77-339 34 7.8e-99 335.57 SMART 1-231 (231) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKG--GELFDTIIKNG
|| ....|||.|.||.. . .. |...|.|  .                ...|||||.| .||||.|||.|... ...|.|   . |  |.||| | |.|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

N------FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAAFTSDDLLFKRCGTPGYVAPEILEDKKYDQ-KVDVFSSG
       |.|  |.....|...||||.| ..|.|||.||||. | .     .||..|||||..         |||| |.|||.|   .|.  |.|. | |
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VILYILLTGCSPFYGKSYNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALN-------DRFF
.|||..|.|. ||.   ..... | .               |.|| ....|.|..||. |.|| .||.       . .|
CILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 13265.AA CAMKL 77-339 35 2.8e-96 307.78 In-house 1-297 (297) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-297/297
Sequence Identity: 35% (106 aa)

YENIKILGKGTFAKVFLTKM-VRGGQEFAVKTFDKRALLTSKNSEKTRTG--------LLNEIQILRKCD---HPNIIKLYEVYESDNY------IYLVQ
|. .| ||||.|.|| | .     |.. |.|  ||. .    ...|   |        .  ||||... .   ||||||||||.| ...      |||| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

NVLKGGE--LFDTIIKNGN----FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLA-----A-FTSDDLLFKRCGTPGY
    |||  ||| |.|.|.    ..|. | ..  |..||..|.| ..| ||||||||. | .. .  .||..|||..       |.....|  .||.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEILED--KKYD-QKVDVFSSGVILYILLTGCSPFYGKSYN----EILSKNKNCQISYDFNE-LGVKVSQEATELLKKMLDVDPKTRITASQALNDRF
 ||||...  |.|| .|||. | ||||| ...|  || . .||    .   . .. ...  ...   ..|| ..  |..||| |.|. |.|. | .|...
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M

Kinase 13265.AA Pkinase 77-339 31 2.1e-93 321.38 Pfam 1-293 (293) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-293/293
Sequence Identity: 31% (93 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKCDHPNIIKLYEVYESDNYIYLVQNVLKGG----ELFDTII-
|. ....|.|.|..|.. . .  |...|||...||    .|. ...|.   .||||.....||||..||...|....||.|.  . ||    .||| |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-KNGNF--SEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDF--QIKLADFGLAA---FTSDDLLFKRCGTPGYVAPEILE-DKKYDQKVD
 ..|.|  ||. . ... |.|..|||.|...|.|||.||||. .. . ..    .|..|||||.     ..  .  .||||.|.|||..  ...|..|||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VFSSGVILYILLTGCSPFYGK------SYNEILSKNKNCQISYDFN-----------------ELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF
..| |.|||..|.|  ||.|.      . .... ... .....|.                  .. ...|.|. ...|..|..||| |.|| |.|.. .|
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF





Kinase 13265.AA Ciliate-E2 77-339 30 1.5e-92 313.75 In-house 1-365 (365) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-365/365
Sequence Identity: 30% (116 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFA--VKTFDK--------------RALLTSKNSEKTRTGLLNEIQ--------------ILRKCDHPNIIKLYE
|. ||..|.|.|..|.. |  . ...||  ... .|               |. . |....  .   . |               ||.. .||||||.||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VYE--SDNYIYLVQNVLKGGELFDTIIKN-----------GNFSEKNAAKIIHQLLS---------------ALEYIHAKN-IMHRDIKPENLILVDKSD
...  .||.||||   ..||.||| |..|           ..|.|| ...|. |.|.               ||||.| || |.||||||||...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

DFQIKLADFGLAAFTSDD---------------------------------LLFKRCGTPGYVAPEILEDKK---------YDQKVDVFSSGVILYILLT
   ||..||||. . .||                                 . .  ||||||.|||||. ||         || |.|..| |||||..|.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GCSPFYGKSYNEILSKNKNCQISYDFNE-------------LGVKVSQEATELLKK----MLDVDPKTRIT-ASQALNDRFF
|  ||        . ..|.|.|.....|                |.|||.  |.||    ||..||. ||| ..|.||  .|
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 13265.AA CAMK-Unique 77-339 28 3.2e-84 277.89 In-house 1-363 (363) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-363/363
Sequence Identity: 28% (102 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDK-----RALLT-------SKNSEKTRTG-LLNEIQILRKCDHPNIIKLYEV----YESDN-------
|....|.|.|.| .|. ..    | ..|.| . |      ....        | .|| |   | .|.||... |||||||||..    .. ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YIYLVQNVLKGGELFDTIIK--------------------NGNFSE--KNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKS--D---
        |.|.|.  . ||.||| |.|                    .| |||    .. |. .||||..| | ..| |||.|.|| |.| .|  |   
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLEN-IMVCYSFKDNNH

---------DFQIKLADFGLAAFTSDDLLF----KRCGTPGYVAP--------------EILEDKKYDQKV----DVFSSGVILYILLTGCSPFYGKSYN
         .  |||.||||..  .         ..|||| |.||              |...  .|||..    |  | |||.|..|.||.||.. . .
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------EILSKNKNCQI-SYDFNELGVK--VSQEATELLKKMLDVDPKTRITASQALNDRFF
        ||... . ... ..|    ..   .||||. ..|. . |||. |..|...|   ..
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase 13265.AA MARK 77-339 36 4.8e-79 258.05 In-house 1-262 (262) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-262/262
Sequence Identity: 36% (101 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSE-KTRTGLLNEIQILRKCDHPNIIKLYEVYE--SDNY-IYLVQNVLKGGELFDTIIK
|. .| .|.|..||| |   .. |...|.|. .|      | .. ...  .  ||.|..| ||||||||..| |    .  |||.     ||||.| |..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEK-----FKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKA

N--GNFSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAA-FTSDDLLFKRCGTPGYVAPEILEDKKYD-QKVDVFSSGV
   |  .|. | .| .|..||..| | ||| |||||||| ||.|.    .||..|||... .... .|   |||| | ||||.. |.|| .|||. | ||
HPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPEN-ILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGV

ILYILLTGCSPFYGKS--YNEILSKNKNCQISYDFNELGVKVSQEATELLKKMLDVDPKTRITASQALNDRFF
.||....|. || |..  |.|.  |  ... .. ..     || |.  |....| |.|. |.|... ......
VLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH-----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 13265.AA RSK 80-339 32 2.6e-77 263.17 In-house 1-278 (278) Show / Hide
Range on Protein: 80-339
Range on HMM: 1-278/278
Sequence Identity: 32% (92 aa)

IKILGKGTFAKVFLTKMV---RGGQEFAVKTFDKRALLTS-KNSEKTRTGLLNEIQILRKCD-HPNIIKLYEVYESDNYIYLVQNVLKGGELFDTIIKNG
.| ||.| . |||| . .     ||..|.|  .|. . .. |  . |.|    |..||  |  ||.|..|..... . ..||.   ..|||||. . | .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMT----ERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK

N---FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDD-FQIKLADFGLAAF-TSD--DLLFKRCGTPGYVAPEILE---DKK-YDQKVDV
    |||. |. .. .. .|.|..| . | |||.|||| .. |.| .   ||| |||..     |   .. . |.|  |.|||.|     .. .|. .|.
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDW

FSSGVILYILLTGCSPFYG---KSYNEILSKNKNCQISYDFN--ELGVKVSQEATELLKKMLDVDPKTRIT-----ASQALNDRFF
.| ||..| .||||.||.|   .. .||. . .....| ..   .   ..|||| .|..||| .||. |..     |.. ... .|
WSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ---YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 13265.AA Ciliate-E2-Unclassified 77-339 24 3.4e-77 262.75 In-house 1-352 (352) Show / Hide
Range on Protein: 77-339
Range on HMM: 1-352/352
Sequence Identity: 24% (88 aa)

YENIKILGKGTFAKVFLTKMVRGGQEF-------AVKTFDKRALLTSKNSEKTRTGLLNEIQ-------------ILRKCDHPNIIKLYEVYESDNYIYL
|. ||..|.| |.||.. .    . ..        .. ....  ....  ..     .|...             ||. ..||.|.|.... .....||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VQNVLKGGELFDTIIKNGN-----------------FSEKNAA-----KIIHQLLSALEYIHAKN-IMHRDIKPENLILVDKSDDFQIKLADFGLAA---
|   ..||.|.. | |...                 |.|..|.     ... |.|..|||.| || | ||||||||... ..   ..||..|||..    
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------FTSDDLLFKRCGTPGYV----APEILEDKKYD----QKVDVFSSGVILYILLTGCSPFYGKSYNE---------------ILSKNK
              .......  .||||.|     |||.|. ..||     |.|..| ||||| .|.|  |||......               .| .|.
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

NCQISYDFNELG----VKVSQEATELLK----KMLDVDPKTRITASQALNDRFF
. .. . ...       ..|.|| ....    |||...|. |||..|.||  .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 13265.AA TyrKc 77-338 24 8.3e-17 49.01 SMART 1-280 (280) Show / Hide
Range on Protein: 77-338
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

YENIKILGKGTFAKVFLTKMVRGGQEFAVKTFDKRALLTSKNSEKTRTGLLNEIQILRKC--DHPNIIKLYEVYESD-------NYIYLVQNVLKGGELF
 . .|.|| | | .|.. ..    .. |||.  . |          |  ...|..|..|   .||||..|| |  ..         ...|    ..| | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

DTIIKNGN-FSEKNAAKIIHQLLSALEYIHAKNIMHRDIKPENLILVDKSDDFQIKLADFGLAAFTSDD--------LLFKRC--GTPG-----YVAPEI
| . |... .. |   .. .|  .  ||.| ||. |||.   | .||..    ..| .||||. .  ||           |.   |. .       ||| 
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARN-CLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LEDKKYDQKVDVFSSGVILYILLTGCSPFYG------KSYNEILSKNKNCQISYDFNE-----LGVKVSQEATELLKKMLDVDPKTRITASQALNDRF
. ..|.  | ||.| || .. ..| . . |       .|  |.. . |.        .       |  ..|  .. |.  . ||. | | |.   ..|
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF

Kinase 13265.AA Pkinase_Tyr 77-205 25 3e-11 38.71 Pfam 1-137 (270) Show / Hide
Range on Protein: 77-205
Range on HMM: 1-137/270
Sequence Identity: 25% (36 aa)

YENIKILGKGTFAKVFLTKMV----RGGQEFAVKTFDKRALLTSKNSEKT--RTGLLNEIQILRKC-DHPNIIKLYEVYE-SDNY--IYLVQNVLKGGEL
 . .| ||.| | .|.. ..      .... |||.  |      . ...   |  ...|..|...  .||||..|| |    .    ||.|    ..| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

FDTIIK----NGNFSEKNAAKIIHQLLSALEYIHAKNIMHRDI
 |   |    ..... |   .. .|  ...|| ..||. |||.
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase 13265.AA Pkinase_Tyr 211-291 31 0.014312 9.33 Pfam 142-227 (270) Show / Hide
Range on Protein: 211-291
Range on HMM: 142-227/270
Sequence Identity: 31% (28 aa)

ILVDKSDDFQIKLADFGLAAFT-SDDLL-FKRCGTPG---YVAPEILEDKKYDQKVDVFSSGVILYILLTGC-SP-FYGKSYNEILSK
.||..  ....| .|||||    .||    || |..      ||| . ..|.  | || | || .. ..| . .| ..| | .|.. .
CLVTE--NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEY