Gene 10284 (Tetrahymena)

10284

Species: Tetrahymena
Alias: 10284, 81, PreTt10284, TTHERM_00377310, 40.m00169
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
10284.AA Protein None 313 None Fasta, JSON
10284.kin_dom Protein Kinase Domain None 257 None Fasta, JSON
10284.NA RNA None 942 None Fasta, JSON

Protein domain

Protein domains of 10284.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10284.AA CAMK1 12-268 48 5.70000000001e-202 592.98 In-house 1-276 (276) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-276/276
Sequence Identity: 48% (135 aa)

YTFDKVLGEGSFGIVKRAIKKDT---GEAFAVKMIK-KENLESDDM---NALQQEVEILT---EIDHPNVVKLYEIYEDDAYFYMVLELMTGGELFQRIV
| |.|..|.|.|..|.....|.|   |...|.|.|. |.... .||   .||..|.||..   .|||||..|.||.||.| .||.|.||.|||||| |||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EADHFSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGAVIK--ISDFGLARFVGEN--TMTTMCGTPGYVAPDIILG---QGYDKTIDYW
| ....|..|....|....|..|.|...|.|||||||||||..|.... ||  |.||||.......  .|.|.|||||||||... .   ..|||..|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SVGVILYIMLCGFPPFYSEN-NDELFELIVKGKFEFPSPAWDSISNE-AKDLIKGLLTVDPKKRFNYEKISAHPWL
|.|||.||.|||.||||.|| ..||||.| |...||||| ||.||.. |||.||..|.||||||...|.. .|||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 10284.AA CAMK 17-268 30 8.3e-137 443.69 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-268
Range on HMM: 1-425/425
Sequence Identity: 30% (130 aa)

VLGEGSFGIVKRAIKKDTG------------EAFAVKMIKKENLESD--------------------------DMNALQQEVEILTE-------IDHPNV
.||.||||.||..| | |.            . .|.|.|.|. | ..                          |.  ...|.||.         .||||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLYEIYED-------------------DAYFYMVL---ELMTGGEL----FQRIVEA---------------DHFSERQAAETIKPVVDALHYCHALNI
.||||.|||                   | ..|||.   |...||||    |..|||                 .|.||.|.  .. ...|.|||| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENLLYATKEPG--------------AVIKISDFGLARFVGEN-------------------------TMTTMCGTPGYVA-PDIILG------
.||||||||.|. .....              . |||.|||.|... ..                          |.|.||||.|.| | ...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------QGYDKTIDYWSVGVILYIMLCGFPPFYSE-------------NNDELFELIVKGKFEFPSPA------------WDSISNE--------AKD
        ..|.. .| ||.||||||||||.||||..             |  |||| | |||..||.|             ||.||.|        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKGLLTVDPKKRFNYEKISAHPWL
||...|.|||.||.. | . .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 10284.AA RAD53 12-268 41 1.5e-136 409.46 In-house 1-305 (305) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-305/305
Sequence Identity: 41% (127 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKK---E---NLESDDMNALQQEVEILTEIDHPNVVKLYEIYED-DAYFYMVLELMTGGELFQRIVEAD
| ..|.|| | ||.||.|..|.|.. .|.| |.|       . ....|  .. |||||. . ||.....|.|... . |.||||||||||||| .||   
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

H----FSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGA---------------VIKISDFGLARFVGEN-TMTTMCGTPGYVAPDIILG
     |.| .. .. .  .||. | | ..|.|||||||| |..... .                .|||.||||..||||   |.|||||| |||| .|..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

Q---------------GYDKTIDYWSVGVILYIMLCGFPPFYSE-----NNDELFELIVK-GKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKIS
.               || |  | || |.||||.|||.|||  .       . ||| |.. ||..||.| ||.||.|||||||..|.|||.||.. ... 
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

AHPWL
 |||.
NHPWM
Kinase 10284.AA CDPK 12-268 43 3.6e-129 398.2 In-house 1-271 (271) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-271/271
Sequence Identity: 43% (117 aa)

YTFDKVLGEGSFGIVKRAIKK-DTGEAF-AVKMIKKENLESDDM-NALQQEVEILTEIDHPNVVKLYEIYEDDAYFYMVLE--LMTGGELFQRIVEADHF
|.. ||||.|.|| |.....|  |..   |.|.|.| ..   .    ...|.||| ..||||..|.|| |.|. ..| |.|  . ||||||..|.|  ||
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGA----VIKISDFGLAR-FVGE-----NTMTTMCGTPGYVAPDIILGQGYDKTIDYWSV
.|..||.... .. |. |||  || ||||||||.|. .|....     ||. |.|... | ..     ..|...|||| |.|| .. .. |..  | || 
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYIMLCGFPPFYSENNDELFELIVKGKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
||||||.||| |||| .|  | .| . |||..|  | ||.||.||||||. .|..|||||.  . . .||| 
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 10284.AA AGC 12-268 27 2.8e-126 328.13 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-395/395
Sequence Identity: 27% (111 aa)

YTFDKVLGEGSFGIVKRAIKK------DTGEAFAVKMIKKEN--------LESDDMNA--------LQQEVEILTEID----------HPNVVK-LYEIY
. | ||.|.|||| |  . ||      |||. .|.|..||.          .   |..        ...| .||....          ||..|| |.  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EDDAY--FYMVLELMT---------GG-ELFQRIV---EADHFSERQAAETIKP-------VVDALHYCHA-LNIAHRD-LKPENLLYATKEPGAVIKIS
.|. .   |.|.|.|          || |||...       .|.| .|   .         .| ||.| |  ..| ||| |||||.|   .     ||..
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKLT

DFGLARFV----------------------------------------------------GENTMTTMCG--TPGYVAPDIILGQGYDKTIDYWS--VGV
||||.  .                                                    .... .|.||  || |.|| |.    |.|. |.||  .|.
DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGC

ILYIMLCGFPPFYSENND----------ELFELIV------KGKFEFPSP------AWDSISNEAKDLIKGLLTVDPKKRFN----------YEKISAHP
..| ||.| ||||..|..          |.|..|       . | .||.|      .....|.|||||||.||..||.||            .| | .||
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

WL
| 
WF
Kinase 10284.AA Ciliate-E2a 12-268 40 1.5e-118 350.56 In-house 1-275 (275) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-275/275
Sequence Identity: 40% (111 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESD-DMNALQQEVEILTEIDHPNVVKLYEIYEDDAYFYMVLELMTGGELFQRIVEADHFSER-
| | |..|.|.|| |. | .|.||. ||.| ..| . ... .  ....|. |. ..||||. ||||.|||. ..|.|.|.  ||||...|.. . | |  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-QAAETIKPVV-DALHYCHALNIAHRDLKPENLLYA--TKE--PGAVIKISDFGLARFV--GEN-TMTTMCGTPGYVA------PDIILGQGYDKTIDYW
 .... ..    ..|||.| .|| ||||||||.|.    |.  . . |||.|||||.|.   |.  | ..||||||||      ....... ||.  | |
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SVGVILYIMLCGFPPFYSENNDELFELIVKGKFEFPSPA-WDSISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
|.|||.||.||| |||. .. .| .... | |. | .|  |  .|.|.|||.|..| .|||||.. . .  ||| 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 10284.AA MAPKAPK 12-268 37 1.2e-113 353.31 In-house 1-292 (292) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-292/292
Sequence Identity: 37% (111 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESDDMNALQQEVEILTEI-DHPNVVKLYEIYED----DAYFYMVLELMTGGELFQRIVE--AD
 . ..|||||. | | .. .| ||. .|||....   .        .|||..    .|||.|.. ...|.    |. ||.|.|.| ||||||.| .    
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQ--PGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHK

HFSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGAVIKISDFGLARF--------VG--ENTMTTMCGTPGYVAPDIILGQG----YDKT
||.||.|.. .| .  |....| .|||||||||||.|. .... ...|..|||.|           .  .....| |.|| |.|| ..  .     ||| 
HFTEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFKEAHTYDKS

IDYWSVGVILYIMLCGFPPFYSENN------D----------ELFELIVKGKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
 | || |||.||||||.|||||.        |          ..|. | .|..|||.. |. ||.||||||. || .||..|   |.. .|||.
CDMWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase 10284.AA S_TKc 12-268 37 6.2e-109 369.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-231/231
Sequence Identity: 37% (102 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESDDMNALQQEVEILTEIDHPNVVKLYEIYEDDAYFYMVLELMTG--GELFQRIVEADH----
|.. ...|.|.|| |.....|.||. .|.|.||         . ...|..|| . .|||.||||....|  ..|||.|.. |  |.||..|..  .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--FSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGAVIKISDFGLARFVGENTMTTMCGTPGYVAPDIILGQGYDK-TIDYWSVGVILYI
  |.| .|.  .. ...|| ||| ..| ||||||||.|  .     .|||.||||||..     ||.|||| |.|| ..   ||.|  .| ||.|.|||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLCGFPPFYSENNDELFELIVKGKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKISA-------HPWL
|||| |||.  . ...|..|.              | ||||.|...|..||.||    .. .       |||.
MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10284.AA DCAMKL 12-268 41 9.5e-108 336.37 In-house 1-279 (279) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-279/279
Sequence Identity: 41% (117 aa)

YTFDKVLGEGSFGIVKRAIKKDTG-EAFAVKM-----------------IKKENLESDDMNALQQEVEILTEIDHPNVVKLYEIYEDDAYFYMVLELMTG
|   .. | | | .|. .... || ...| |.                 |.|...        . ||.|.  |.||....||| .. ..  |.|.|. .|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEH-MIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFQRIVEADHFSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGAV-IKISDFGLARFVGE--NTMTTMCGTPGYVAPDIILGQGYDKT
| ||  |.|   |.||.||  .  .  || | | .|| |||.||||||   .| | . .|  |||||  | .    . | |||| |||| |.   ||   
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

IDYWSVGVILYIMLCGFPPFYSE--NNDELFELIVKGKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
.| |..||||||.||||||| |.  . .|||..|. ||||||.| || ||  |||||. .| |||.||.  | | .||| 
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase 10284.AA Pkinase 12-268 38 8.99999999999e-104 355.85 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-293/293
Sequence Identity: 38% (114 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLES-DDMNALQ-QEVEILTEIDHPNVVKLYEIYEDDAYFYMVLELMTGG----ELFQRIV--EA
|.. ...|.|||| |.....|.||. .||| |||.. .|  |....  .|..|. ...|||.|.||...||. . |||.|.. ||    .|| .|   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DHF--SERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYA-TKEPGAVIKISDFGLARF--VGENTMTTMCGTPGYVAPDIIL-GQGYDKTIDYWSVG
  |  ||...   .. .. .| |||. .| ||||||||.|.  . ...| .||.|||||..     |.||| ||||.|.|| .|. ||.|.. .| ||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

VILYIMLCGFPPFYSE------NNDELFELIVKGKFEFPSPAWDSIS-----------------NEAKDLIKGLLTVDPKKRFNYEKISAHPWL
.|||.|||| |||...      . ......| .....|..| |.|||                  |.||.||..|..||||| . | |  |||.
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 10284.AA CAMKL 12-268 34 9.5e-104 331.98 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-297/297
Sequence Identity: 34% (106 aa)

YTFDKVLGEGSFGIVKRAIK-KDTGEAFAVKMIKKENLE--------------SDDMNALQQEVEILTEID---HPNVVKLYEIYEDDAY------FYMV
|.. |.||.|||| || |.  . |||  |.|.|.|. .               ..||  ...|..|.  ..   |||..||||..|.. .      .|.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LELMTGGE--LFQRIVEADH----FSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKE-PGAVIKISDFGLARFVG------ENTMTTMCGTP
.|.  |||  ||..||.  |    ..|..|    . .|.|..||| ..|.|||.||||.|   .     .|||.|||.. .        .....| ||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

GYVAPDIILG--QGYD-KTIDYWSVGVILYIMLCGFPPFYSE--------NNDELFELIVKGKFEFPSPAWDSISNEAKDLIKGLLTVDPKKRFNYEKIS
 | || |..|  . || . .| || ||||| |.||  ||  .        |. .|.. | .| ...|   | ..| ...|||...|.|.|.||.. . | 
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

AHPWL
 |||.
NHPWM
Kinase 10284.AA CAMK-Unique 12-268 29 1.4e-103 342.86 In-house 1-363 (363) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-363/363
Sequence Identity: 29% (107 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESDDMNA------------------LQQEVEILTEIDHPNVVKLYEI----YEDDA-------
|.. ...|.|.||.|.... . ||  .|.||.||.  ... . .                  |  |..|.   |||| .|||..    ..|.        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YFYMVLELMTGGELFQRIVE--------------------ADHFSE--RQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEP-----
        |.|.|.|. .||.||. |..                      ||||  ....  .  .. |. | | ..| |||||.||... . ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------GAVIKISDFGLARFVGENTMT----TMCGTPGYVAP--------------DIILGQGYDKTI----DYWSVGVILYIMLCGFPPFYSENND-
           ||..||||.. . .| |     |||||| |.||               .| .|.||       | || |||.|.|||| |||..|..| 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ELFELIVKGKF-EFPSPAWDS---ISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
       |.|| | ||.. .|....|..   ||.||||..|...||||..| . . .  |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 10284.AA Pkinase_Tyr 12-96 33 2.7e-21 72.74 Pfam 1-94 (270) Show / Hide 
Range on Protein: 12-96
Range on HMM: 1-94/270
Sequence Identity: 33% (32 aa)

YTFDKVLGEGSFGIVKRAIKK----DTGEAFAVKMIKKENLESDD--MNALQQEVEILTEI-DHPNVVKLYEIYE-DDAY--FYMVLELMTGGEL
 ||.|.||||.|| |.... |    .|.   ||||. ||.  ...  . .. .|..|.... .|||.|.|| .   ..     |.|.|.| .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase 10284.AA TyrKc 12-268 23 2.5e-16 41.28 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YTFDKVLGEGSFGIVKRAIKKDTGEAFAVKMIKKENLESDDMNALQQEVEILTEI--DHPNVVKLYEIYEDD-------AYFYMVLELMTGGELFQRIVE
 |..|.|||| ||.| ... |   .  ||||.|..      . .. .| .|....  .|||.|.|| .  ..          ..|.|.| .| | ... .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ADH-FSERQAAETIKPVVDALHYCHALNIAHRDLKPENLLYATKEPGAVIKISDFGLARFVGEN--------TMTTMC--GTPG-----YVAPDIILGQG
  . .. ..  .    . .   | |  |. ||||   | |.. .    ..|||||||.|....         . ...   |. .       ||  |    
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YDKTIDYWSVGVILY-IMLCGFPPFYS-----ENNDELFELIVKGKFEFPSPA-----WDSISNEAKDLIKGLLTVDPKKRFNYEKISAHPWL
.    | || || .. |.  | .| .       .|.|..|.. .|.   . |          . |  ...|     ||..| . . |  |  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 10284.AA Pkinase_Tyr 150-174 37 0.018532 8.95 Pfam 149-175 (270) Show / Hide 
Range on Protein: 150-174
Range on HMM: 149-175/270
Sequence Identity: 37% (10 aa)

VIKISDFGLARFV-GENTM-TTMCGTP
|.||.|||||| .  . .  ..  |..
VVKICDFGLARDIYNDDYYYRKRGGGK