Gene 8442 (Tetrahymena)

8442

Species: Tetrahymena
Alias: PreTt08442, 369.m00008, TTHERM_01401740, 974, 8442
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
8442.AA Protein None 1274 None Fasta, JSON
8442.kin_dom Protein Kinase Domain None 111 None Fasta, JSON
8442.NA RNA None 3825 None Fasta, JSON

Protein domain

Protein domains of 8442.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 8442.AA HisKA 357-421 22 4.7e-14 53.93 SMART 1-89 (89) Show / Hide 
Range on Protein: 357-421
Range on HMM: 1-89/89
Sequence Identity: 22% (20 aa)

FKNDILSTITHNLKTPLNGIILIAQTLQN-----------QVQSKV-------------KDAVSDILQNSKMLLYMINDILDYSRLSKG
 |.. |... | |.|||..|.. |..||.             ...              ..... |.. .. .. .|||.||.||.  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 8442.AA HisKA 357-421 28 7.4e-14 51.27 Pfam 1-69 (69) Show / Hide 
Range on Protein: 357-421
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

FKNDILSTITHNLKTPLNGIILIAQTLQN--QVQSKV--KDAVSDILQNSKMLLYMINDILDYSRLSKG
 |.. |... | |.|||..|.. |..||.     ..   ..... |.. .. .. .|||.||.||.  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 8442.AA HisK 470-580 29 2.5e-44 153.61 In-house 1-164 (164) Show / Hide 
Range on Protein: 470-580
Range on HMM: 1-164/164
Sequence Identity: 29% (48 aa)

NDFSRIKQILINLVGNAAKCTFEG------SITIIFE--------------------------VTSPNHLLISIKDTGIGMSNETIKSIQK---------
.| .|||||||||..|| | |..|      .|.|..|                          . ..|.. ||..|||.||. |..| | |         
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

------IQMKRKKDMRHGVGIGLLIGKSLLQLVGPD------TEFRIESQENQGSTFSFKVFLV
       . ..||...||.|.|| | ..| ...||.       .. ..|....||||||...  
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 8442.AA HATPase_c 470-580 28 8.5e-19 67.66 Pfam 1-120 (120) Show / Hide 
Range on Protein: 470-580
Range on HMM: 1-120/120
Sequence Identity: 28% (35 aa)

NDFSRIKQILINLVGNAAKCTFE-GSITIIFEVTSPNHLLISIKDTGIGMSNETIKSIQKIQMK-----------RKKDMRHG--VGIGLLIGKSLLQLV
.|  |..|.. |||.|| | | | | ||.  . .  .|. |...|.|.|.. | . || . ...           .  ... |   |.|| | . .....
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMH-SIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GPDTEFRIESQENQGSTFSFKVFLV
| .   ..||....|.||.|.. | 
GGT--IWVESEPGGGTTFTFTLPLE
Kinase 8442.AA HATPase_c 470-581 22 2.3e-12 48.32 SMART 1-130 (130) Show / Hide 
Range on Protein: 470-581
Range on HMM: 1-130/130
Sequence Identity: 22% (32 aa)

NDFSRIKQILINLVGNAAKCTFE--------------GSITIIFEVTSPNHLLISIKDTGIGMSN------ETIKSIQKIQMKRKK-----------DMR
.|  |..|.|.||..|| | | |              | ||.  .        |...|.|.|..       | |. |     . ..             .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

HG--VGIGLLIGKSLLQLVGPDTEFRIESQENQGSTFSFKVFLVH
 |   |.|| | |.. .. | . ...        .||.|.. | .
GGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER
REC 8442.AA REC 1150-1268 25 8.2e-35 122.89 SMART 1-150 (150) Show / Hide 
Range on Protein: 1150-1268
Range on HMM: 1-150/150
Sequence Identity: 25% (41 aa)

IKVLIVDDT----VFNIKALR------NLLQKYKTI-------QVEEAFNGQ-------QAVQKVEQS-------------QFDIIFMDINMP-------
...|||||       . ..||      .||.|           .|.|| .|.       .|......              ..|.|.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VMDGFQATKKIRELQKENKIFYKPIIIIVTAFGDQENRSLSFQSGADEHIEKPLTLDSIQKTI
 |||......||             ||..||..| | |   ...|||  | || ... ....|
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 8442.AA Response_reg 1152-1269 34 1.7e-29 108.2 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1152-1269
Range on HMM: 1-115/115
Sequence Identity: 34% (41 aa)

VLIVDDTVFNIKALRNLLQKYKTI-QVEEAFNGQQAVQKVEQSQFDIIFMDINMPVMDGFQATKKI-RELQKENKIFYKPIIIIVTAFGDQENRSLSFQS
||||||   . ..||..|..   .  |.|| .|..|...... ..|.|.|||||| |||......| |... . .    . ||..||.|| . .   .| 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDDAVEALQA

GADEHIEKPLTLDSIQKTIY
||. .| ||  .| . . | 
GANDYITKPFDPDELHAAIR