Gene 8067 (Tetrahymena)

8067

Species: Tetrahymena
Alias: TTHERM_00502280, 3716.m00097, 8067, 63.m00245, 392, PreTt08067
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
8067.AA Protein None 1585 None Fasta, JSON
8067.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
8067.NA RNA None 4758 None Fasta, JSON

Protein domain

Protein domains of 8067.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 8067.AA HisKA 601-664 28 1.1e-14 54.22 Pfam 1-69 (69) Show / Hide 
Range on Protein: 601-664
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

FKDKMLSTVTHDLKTPLNSIIMILENSFELGGLNKKQ-----RKIILQNSQMLMSLINDILDYSQLRRD
 | ..|... |.|.|||..|.. .|   . . |. .|      ..|.. .| . .||||.||.|...  
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 8067.AA HisKA 601-664 21 9.4e-14 52.93 SMART 1-89 (89) Show / Hide 
Range on Protein: 601-664
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

FKDKMLSTVTHDLKTPLNSIIMILENSFE---------LGGLNKKQ----------------RKIILQNSQMLMSLINDILDYSQLRRD
 |...|... |.|.|||..|.. .|   .          . |. .|                 ..|.. .. . .||||.||.|...  
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 8067.AA HisK 711-826 37 4.1e-60 206.02 In-house 1-164 (164) Show / Hide 
Range on Protein: 711-826
Range on HMM: 1-164/164
Sequence Identity: 37% (62 aa)

QDERRIKQILVNLIGNALKFTQQ-----KGKIEVIVK--------------------------QKYIDCIQISVKDTGTGISEQIQKKLFQFFN------
.|..||||||.|||.|||||||.     .|.|...|.                          ..  ..|||||.||| |..|..|||.|..|.      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDHSERANNRHGIGLGLAICKQLNNQLGPW------HEIKLKSKVDQGSKFTFCIYTN
     ||.|..  ||.||.||||.||..|  .|||.      ..|...|.|..||.|.|.|| |
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 8067.AA HATPase_c 711-826 31 5.8e-26 92.59 Pfam 1-120 (120) Show / Hide 
Range on Protein: 711-826
Range on HMM: 1-120/120
Sequence Identity: 31% (39 aa)

QDERRIKQILVNLIGNALKFTQQKGKIEVIVKQKYIDCIQISVKDTGTGISE------QIQKKLFQFFNTFDHSERANNRHG--IGLGLAICKQLNNQLG
 |..|..|.. ||..||.|.|.. |.|.| |..   | ..|.|.|.| ||..      . . ..|. | ..| . |  .. |   ||||.||...  |.|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG

PWHEIKLKSKVDQGSKFTFCIYTN
   .| . |....|..||| .   
--GTIWVESEPGGGTTFTFTLPLE
Kinase 8067.AA HATPase_c 711-827 26 1.2e-25 92.45 SMART 1-130 (130) Show / Hide 
Range on Protein: 711-827
Range on HMM: 1-130/130
Sequence Identity: 26% (38 aa)

QDERRIKQILVNLIGNALKFTQQ-------------KGKIEVIVKQKYIDCIQISVKDTGTGISE------QIQKKLFQFFNTFDH-------SERANNR
 |..|..|.| ||..||.|.|..              |.|.| |.       .|.|.|.| ||..      ......|. | ..|        ..|. ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

HG--IGLGLAICKQLNNQLGPWHEIKLKSKVDQGSKFTFCIYTNL
 |   ||||.|||.. .|.| .  |..       ..||| .   .
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Response_reg 8067.AA Response_reg 1457-1569 28 1.3e-17 65.65 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1457-1569
Range on HMM: 1-115/115
Sequence Identity: 28% (34 aa)

VLIADDSPFNIFCLKQILTKNINL-NIFDAYNGNEALNSYKQNRQQIIFMDLNMPVLDGYECLKCI-RQYEEENHIEEKTKVIVISAQEY-----EPFFS
|||.||.| .   |.|||..   . ..  |..| |||.  ....  .|.||.||| .||.| .. | || . . .    |..|...| .      | .  
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDDAVEALQA

NFDGYLSKPIKLIDMINLLQ
  ..|..||... .... ..
GANDYITKPFDPDELHAAIR
REC 8067.AA REC 1455-1568 18 1.5e-15 58.93 SMART 1-150 (150) Show / Hide 
Range on Protein: 1455-1568
Range on HMM: 1-150/150
Sequence Identity: 18% (30 aa)

SKVLIADDS----PFNIFCLK------QILTKNINL-------NIFDAYNGN-------EALNSYKQNR-------------QQIIFMDLNMP-------
 ..||.||.    | .   |.      ..|.|           ..  | .|        |||.  ...|              ..|.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VLDGYECLKCIRQYEEENHIEEKTKVIVISAQEY-----EPFFSNFDGYLSKPIKLIDMINLL
 .||.| .. ||            ..|...|        . . .  |.|..||... ...  .
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI