Gene 7982 (Tetrahymena)
7982
Sequence
Protein domains of 7982.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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GCV_T | 7982.AA | GCV_T | 67-279 | 36 | 8.7e-74 | 256.25 | Pfam | 1-205 (205) | Show / Hide |
Range on Protein: 67-279 Range on HMM: 1-205/205 Sequence Identity: 36% (79 aa) LFDVSHMGQVKIRGKDSVDFIEKLIVGDIRGKPVAEGFLSLILNKNAGIIDDTIVTKFDDH-IHMVVNGANKYIDLEHMKKLKEEFFANSDVSIEYLDT- ||||||||.....| | ..| ..| .|. .... .. .....| ..|||||..|.. .|. . .|||.||. |.....| ... ..|| .. .. LFDVSHMGKIRVSGPDAAAFLQRLCTNDVSKLKPGQARYTCMCNEQGGIIDDFTVYRLGDDHFWLVVNAANREKDWAWLRKHIFWW--DFDVTVTDVTDE RQLIAIQGPKAAQVLQNLTDTDLSKIKFMHHVDLTLKGGMKVNACRCGYTGEDGFEISVSEQEAVQLAELLLANPL---LKPAGLGARDSLRVEAGLCLH . .||.|||||..||| || .. ..||.. . ..|.|||||||.||.| .||.... |.. .||.||||.|.||.|||..| WAMIAVQGPKAREVLQKLT---NDAFPFMQFREI--------RVSRTGYTGEDGWEIYVPAEYAVAVWDALMEAGKEHGVKPCGLGAWDTLRIEAGYPLW GQDMSPQISPAEATLLWT |.||.....| || | |. GHDMDEDTTPHEAGLGWF |
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GCV_T_C | 7982.AA | GCV_T_C | 292-385 | 32 | 9.2e-27 | 95.81 | Pfam | 1-105 (105) | Show / Hide |
Range on Protein: 292-385 Range on HMM: 1-105/105 Sequence Identity: 32% (34 aa) QKFLGSEVLAKQRKEGVS--QKRVGF-AVK-NNGIIRQGCDVLDEQG-NKVGHVSSGTYSPILKKGVGMIFV-P--PALSSVGQQL-KAVS--KGKEFPI |.| |.||.|...|| ...||. .. .|. |.|..|..|.| ...|.|.|||||| |.|...| .| . |. . .|... .. ||..| GCFIGKEALARQKARGVKRRRRLVGLHEMDGRDGPPRHGYPVYAEDGWEVIGWVTSGTYSPTLGKNIAMAYVKDRVPEHAKPGTEVYEVEIWTRGKRYPA EFVIL . | . TVVKW |
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PAS | 7982.AA | PAS | 458-523 | 20 | 3.2e-05 | 24.57 | SMART | 1-68 (68) | Show / Hide |
Range on Protein: 458-523 Range on HMM: 1-68/68 Sequence Identity: 20% (14 aa) KFYRSLLQVIPEGLAIINLDKKLLYANPTLKKIFQVNKKEDILNALMNLGKSDEQ---EGKEKIFKSPK .||..|. .|.|. ....| . .|.||. ..| ..| | . . .| ... . .| . .. . ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ |
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HisKA | 7982.AA | HisKA | 1003-1071 | 31 | 9.1e-11 | 40.5 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 1003-1071 Range on HMM: 1-69/69 Sequence Identity: 31% (22 aa) NKMKIFGSLSHELRTPLNCSISMLEVLKDQLSQQNPQY-INEYINPALFSNKLLLNQINDILDFVQMDSG | . . ..||||||||. . ..|.|.| . ..|. . ||.. .. . . ....|||.||| ....| AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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HisKA | 7982.AA | HisKA | 1003-1071 | 23 | 3.7e-10 | 41.01 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 1003-1071 Range on HMM: 1-89/89 Sequence Identity: 23% (21 aa) NKMKIFGSLSHELRTPLNCSISMLEVLKDQL--------SQQNPQYI------------NEYINPALFSNKLLLNQINDILDFVQMDSG | . . ..||||||||. . ..|.|.|.. . .|. . ||.. .. . . ....|||.||. ....| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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Kinase | 7982.AA | HisK | 1118-1238 | 33 | 1.4e-57 | 197.64 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 1118-1238 Range on HMM: 1-164/164 Sequence Identity: 33% (55 aa) SDPNRIRQIILNFLSNSLKFTQSG------YIEIGIKLVD--------------------------VGIYNIYVRDTGIGITESNLENLFDFCGKI---- ||||||.||..|..||.||||| | ||.| ... . ... |.| |||.|..|......|...|.| SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH -----NYNKKDEVLNNQGCGLGLTISNSIAKDLIDRNQ--YEGGIKVESKYGEGSTFSILIQDR ..|.... .| .||||||||.|..|| | ... . .||.|.|..|.|||||..|... QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
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Kinase | 7982.AA | HATPase_c | 1118-1238 | 24 | 4.4e-19 | 68.65 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 1118-1238 Range on HMM: 1-120/120 Sequence Identity: 24% (34 aa) SDPNRIRQIILNFLSNSLKFTQS-GYIEIGIKLVDVGIYNIYVRDTGIGITE------SNLENLFD-------FCGKINYNKKDEVLNNQG--CGLGLTI ||.|..|...|...|..|.|.. | |.. .. | . | |.|.|.||.. .....|. . .| ||||.| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGLYI SNSIAKDLIDRNQYEGGIKVESKYGEGSTFSILIQDR .. |.. ..| | |||. |.|.||.. . . CRRIVEQ------HGGTIWVESEPGGGTTFTFTLPLE |
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Kinase | 7982.AA | HATPase_c | 1118-1239 | 21 | 1.1e-16 | 62.71 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 1118-1239 Range on HMM: 1-130/130 Sequence Identity: 21% (32 aa) SDPNRIRQIILNFLSNSLKFTQS--------------GYIEIGIKLVDVGIYNIYVRDTGIGITE------SNLENLFDFCGKINYNK-----KDEVLNN ||.|.||...| |.|..|.|.. | |.. .. | |.|.|.||.. ....|. .. . . . . GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY QG--CGLGLTISNSIAKDLIDRNQYEGGIKVESKYGEGSTFSILIQDRR .| ||||.|...|.. . . |.|| .||.. . .| GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER |
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REC | 7982.AA | REC | 1592-1716 | 17 | 6.2e-22 | 80.12 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1592-1716 Range on HMM: 1-150/150 Sequence Identity: 17% (29 aa) PQIIIVDDN----QFNLYALS------KIIKQFKFQ--------CLTISNSL-------ETMHKIKQMFSQKCCLM------PKIIFMDIDMP------- . | ||||. . .. .|. .. .. .. . . . | . .... ..| | .|.||| || MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG IKDGYQVASEINQFYKDAGITNLPTIIACTSYVGQEDKDMAFQSGMNDFINKPILKNAFVQLL ||.... .| ||..|.. . ||. |...|..|.| ||. . ... . GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 7982.AA | Response_reg | 1594-1717 | 24 | 4e-15 | 56.74 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1594-1717 Range on HMM: 1-115/115 Sequence Identity: 24% (31 aa) IIIVDDNQFNLYALSKIIK-QFKF-QCLTISNSLETMHKIKQMFSQKCCLMPKIIFMDIDMPIKDGYQVASEI-NQFY-KDAGITNLPTIIACTSYVGQE ..||||.. .. .| .|.. . . . . .. | ....... | .|.|||.|| ||......| | . . . ||.||.. . VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDED DKDMAFQSGMNDFINKPILKNAFVQLLI |. |.| |.||.| ||. ... .. . DAVEALQAGANDYITKPFDPDELHAAIR |