7982

Species: Tetrahymena
Alias: 1040, PreTt07982, 63.m00160, 3716.m00014, 7982, TTHERM_00499390
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7982.AA Protein None 1724 None Fasta, JSON
7982.kin_dom Protein Kinase Domain None 110 None Fasta, JSON
7982.NA RNA None 5175 None Fasta, JSON

Protein domain

Protein domains of 7982.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GCV_T 7982.AA GCV_T 67-279 36 8.7e-74 256.25 Pfam 1-205 (205) Show / Hide
Range on Protein: 67-279
Range on HMM: 1-205/205
Sequence Identity: 36% (79 aa)

LFDVSHMGQVKIRGKDSVDFIEKLIVGDIRGKPVAEGFLSLILNKNAGIIDDTIVTKFDDH-IHMVVNGANKYIDLEHMKKLKEEFFANSDVSIEYLDT-
||||||||.....| | ..| ..|  .|. .... .. .....| ..|||||..|.. .|. . .|||.||.  |.....|  ...  ..|| .. ..  
LFDVSHMGKIRVSGPDAAAFLQRLCTNDVSKLKPGQARYTCMCNEQGGIIDDFTVYRLGDDHFWLVVNAANREKDWAWLRKHIFWW--DFDVTVTDVTDE

RQLIAIQGPKAAQVLQNLTDTDLSKIKFMHHVDLTLKGGMKVNACRCGYTGEDGFEISVSEQEAVQLAELLLANPL---LKPAGLGARDSLRVEAGLCLH
. .||.|||||..||| ||   .. ..||.. .          ..|.|||||||.||.|   .||.... |..      .||.||||.|.||.|||..| 
WAMIAVQGPKAREVLQKLT---NDAFPFMQFREI--------RVSRTGYTGEDGWEIYVPAEYAVAVWDALMEAGKEHGVKPCGLGAWDTLRIEAGYPLW

GQDMSPQISPAEATLLWT
|.||.....| || | |.
GHDMDEDTTPHEAGLGWF

GCV_T_C 7982.AA GCV_T_C 292-385 32 9.2e-27 95.81 Pfam 1-105 (105) Show / Hide
Range on Protein: 292-385
Range on HMM: 1-105/105
Sequence Identity: 32% (34 aa)

QKFLGSEVLAKQRKEGVS--QKRVGF-AVK-NNGIIRQGCDVLDEQG-NKVGHVSSGTYSPILKKGVGMIFV-P--PALSSVGQQL-KAVS--KGKEFPI
  |.| |.||.|...||   ...||.  ..  .|. |.|..|..|.| ...|.|.|||||| |.|...| .| .  |. . .|... ..     ||..| 
GCFIGKEALARQKARGVKRRRRLVGLHEMDGRDGPPRHGYPVYAEDGWEVIGWVTSGTYSPTLGKNIAMAYVKDRVPEHAKPGTEVYEVEIWTRGKRYPA

EFVIL
. | .
TVVKW

PAS 7982.AA PAS 458-523 20 3.2e-05 24.57 SMART 1-68 (68) Show / Hide
Range on Protein: 458-523
Range on HMM: 1-68/68
Sequence Identity: 20% (14 aa)

KFYRSLLQVIPEGLAIINLDKKLLYANPTLKKIFQVNKKEDILNALMNLGKSDEQ---EGKEKIFKSPK
 .||..|. .|.|. ....| . .|.||.  ..|   ..| | . . .|   ...   . .| . .. .
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ

HisKA 7982.AA HisKA 1003-1071 31 9.1e-11 40.5 Pfam 1-69 (69) Show / Hide
Range on Protein: 1003-1071
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

NKMKIFGSLSHELRTPLNCSISMLEVLKDQLSQQNPQY-INEYINPALFSNKLLLNQINDILDFVQMDSG
 | . . ..||||||||.  . ..|.|.|  . ..|.  . ||.. .. . . ....|||.||| ....|
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 7982.AA HisKA 1003-1071 23 3.7e-10 41.01 SMART 1-89 (89) Show / Hide
Range on Protein: 1003-1071
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

NKMKIFGSLSHELRTPLNCSISMLEVLKDQL--------SQQNPQYI------------NEYINPALFSNKLLLNQINDILDFVQMDSG
 | . . ..||||||||.  . ..|.|.|..        .  .|. .             ||.. .. . . ....|||.||. ....|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 7982.AA HisK 1118-1238 33 1.4e-57 197.64 In-house 1-164 (164) Show / Hide
Range on Protein: 1118-1238
Range on HMM: 1-164/164
Sequence Identity: 33% (55 aa)

SDPNRIRQIILNFLSNSLKFTQSG------YIEIGIKLVD--------------------------VGIYNIYVRDTGIGITESNLENLFDFCGKI----
||||||.||..|..||.||||| |      ||.| ... .                           ... |.| |||.|..|......|...|.|    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----NYNKKDEVLNNQGCGLGLTISNSIAKDLIDRNQ--YEGGIKVESKYGEGSTFSILIQDR
     ..|.... .| .||||||||.|..|| |  ...  . .||.|.|..|.|||||..|...
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 7982.AA HATPase_c 1118-1238 24 4.4e-19 68.65 Pfam 1-120 (120) Show / Hide
Range on Protein: 1118-1238
Range on HMM: 1-120/120
Sequence Identity: 24% (34 aa)

SDPNRIRQIILNFLSNSLKFTQS-GYIEIGIKLVDVGIYNIYVRDTGIGITE------SNLENLFD-------FCGKINYNKKDEVLNNQG--CGLGLTI
 ||.|..|...|...|..|.|.. | |.. ..  | .   | |.|.|.||..       .....|.                     . .|   ||||.|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---------SR-RKYGGGLTGLGLYI

SNSIAKDLIDRNQYEGGIKVESKYGEGSTFSILIQDR
.. |..       ..| | |||. |.|.||.. .  .
CRRIVEQ------HGGTIWVESEPGGGTTFTFTLPLE

Kinase 7982.AA HATPase_c 1118-1239 21 1.1e-16 62.71 SMART 1-130 (130) Show / Hide
Range on Protein: 1118-1239
Range on HMM: 1-130/130
Sequence Identity: 21% (32 aa)

SDPNRIRQIILNFLSNSLKFTQS--------------GYIEIGIKLVDVGIYNIYVRDTGIGITE------SNLENLFDFCGKINYNK-----KDEVLNN
 ||.|.||...| |.|..|.|..              | |.. ..        | |.|.|.||..        ....|.  ..   .      .  . . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--CGLGLTISNSIAKDLIDRNQYEGGIKVESKYGEGSTFSILIQDRR
.|   ||||.|...|.. .  .      |.||      .||.. .  .|
GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER

REC 7982.AA REC 1592-1716 17 6.2e-22 80.12 SMART 1-150 (150) Show / Hide
Range on Protein: 1592-1716
Range on HMM: 1-150/150
Sequence Identity: 17% (29 aa)

PQIIIVDDN----QFNLYALS------KIIKQFKFQ--------CLTISNSL-------ETMHKIKQMFSQKCCLM------PKIIFMDIDMP-------
. | ||||.    . .. .|.      .. ..  ..        . .  .         | . ....  ..|          | .|.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKDGYQVASEINQFYKDAGITNLPTIIACTSYVGQEDKDMAFQSGMNDFINKPILKNAFVQLL
  ||.... .|              ||..|.. . ||.  |...|..|.| ||.  . ... .
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 7982.AA Response_reg 1594-1717 24 4e-15 56.74 Pfam 1-115 (115) Show / Hide
Range on Protein: 1594-1717
Range on HMM: 1-115/115
Sequence Identity: 24% (31 aa)

IIIVDDNQFNLYALSKIIK-QFKF-QCLTISNSLETMHKIKQMFSQKCCLMPKIIFMDIDMPIKDGYQVASEI-NQFY-KDAGITNLPTIIACTSYVGQE
..||||.. .. .| .|.. .  .  . . ..  | .......        | .|.|||.||  ||......|  | .  .      . ||.||..   .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ------TPIIMCTAHGDED

DKDMAFQSGMNDFINKPILKNAFVQLLI
|.  |.| |.||.| ||. ... .. . 
DAVEALQAGANDYITKPFDPDELHAAIR