7838

Species: Tetrahymena
Alias: 7838, 185.m00059, TTHERM_00989480, 850, PreTt07838
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7838.AA Protein None 1133 None Fasta, JSON
7838.kin_dom Protein Kinase Domain None 119 None Fasta, JSON
7838.NA RNA None 3402 None Fasta, JSON

Protein domain

Protein domains of 7838.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 7838.AA HisKA 561-628 31 7.7e-11 40.76 Pfam 1-69 (69) Show / Hide
Range on Protein: 561-628
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

FKSKMLASISHELRTPLNCSIGMLQLIYD-NHYAQKEVIDQFIVPALYSNKLLLNIINDILDFNQINVG
 |...||..||||||||.  .|...|. |  .   .. . ...  .. . . ....|||.||| .|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 7838.AA HisKA 561-628 23 3.6e-10 41.05 SMART 1-89 (89) Show / Hide
Range on Protein: 561-628
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

FKSKMLASISHELRTPLNCSIGMLQLIYD----------NHYAQKEV-----------IDQFIVPALYSNKLLLNIINDILDFNQINVG
 |...||..||||||||.  .|...|. |               ...           . ...  .. . . ....|||.||. .|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 7838.AA HisK 677-795 32 1.3e-53 184.46 In-house 1-164 (164) Show / Hide
Range on Protein: 677-795
Range on HMM: 1-164/164
Sequence Identity: 32% (54 aa)

TDPQRVTQIMLNLLSNAVKFTEQGG-----KITVQLQEVE--------------------------KNLLKIDISDTGCGIPLKKLRNLFNNFGKVNRN-
.||.|. ||..||.|||.|||..||     .|...... .                          |||..|...|||||.| ... ..|..||..... 
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-------ESAEFNDGAFGAGLGLTISNKLAKGIG------NNRSIKVVTQLYQGSTFTFYIQNQ
       .  . ..   |.||||||.|.||||.|      .||.|.|. .  .||||.|||.|.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 7838.AA HATPase_c 677-795 29 1.2e-24 88.03 Pfam 1-120 (120) Show / Hide
Range on Protein: 677-795
Range on HMM: 1-120/120
Sequence Identity: 29% (37 aa)

TDPQRVTQIMLNLLSNAVKFTEQGGKITVQLQEVEKNLLKIDISDTGCGIPL------KKLRNLFNNFGKVNRNESAEFNDGAFG--AGLGLTISNKLAK
.|| |. |...||..||.|.|..||.||| . . . . . | ..|.|.|||       ... ..|  |...         .   |   ||||.|......
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD---SR-RKYGGGLTGLGLYICRRIVE

GIGNNRSIKVVTQLYQGSTFTFYIQNQ
  |    | | ..  .|.||||..  .
QHGGT--IWVESEPGGGTTFTFTLPLE

Kinase 7838.AA HATPase_c 677-796 26 2.6e-24 88.02 SMART 1-130 (130) Show / Hide
Range on Protein: 677-796
Range on HMM: 1-130/130
Sequence Identity: 26% (38 aa)

TDPQRVTQIMLNLLSNAVKFTEQ-------------GGKITVQLQEVEKNLLKIDISDTGCGIPL------KKLRNLFNNFGKVN----RNESAEFNDGA
.|| |. |...|||.||.|.|..             ||.||| .         | ..|.|.|||       ... ..|  |...     | .... .   
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

FG--AGLGLTISNKLAKGIGNNRSIKVVTQLYQGSTFTFYIQNQK
 |   ||||.|......  |    |.|       .||||..  ..
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 7838.AA REC 959-1123 19 2.4e-07 31.65 SMART 1-150 (150) Show / Hide
Range on Protein: 959-1123
Range on HMM: 1-150/150
Sequence Identity: 19% (38 aa)

SDILIVDDN----EFNILTLK------SLLGQYELK--------VDFALNGK-------QAFEKVQQKIQINTQCVSHVKKVIQQDYSKRKTQEEDDIEQ
  ||||||.    . .  .|.       || .            || | .|.       .|.|..|.. .                      ..||... 
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRD----------------------KKEDATTD

QNQIPKQCQKLRCQSYQLIFMDIDMP-------IMNGYQATIKILDFFKQQNSQIKKPFISTCSAFVTDQDKEKAKEVGMQFFIEKPIVKKKLEYLL
 .           . ..||.||| ||        |.|.... .|               |  ..|. ...|...| |.|.  .| ||.  . |   .
-QS----------EPPDLIIMDIMMPGDPFEDGGMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 7838.AA Response_reg 961-1001 30 6e-06 24.0 Pfam 1-43 (115) Show / Hide
Range on Protein: 961-1001
Range on HMM: 1-43/115
Sequence Identity: 30% (13 aa)

ILIVDDNEFNILTLKSLLG-QYEL-KVDFALNGKQAFEKVQQK
.|||||.. .   |. .|  .. . .|. | .|..| |..|..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEH

Response_reg 7838.AA Response_reg 1047-1124 26 0.000194 18.46 Pfam 43-115 (115) Show / Hide
Range on Protein: 1047-1124
Range on HMM: 43-115/115
Sequence Identity: 26% (21 aa)

QSYQLIFMDIDMPIMNGYQATIKI-LDFF-KQQNSQIKKPFISTCSAFVTDQDKEKAKEVGMQFFIEKPIVKKKLEYLLF
. . ||.|||.|| |.|.... .|       |       . |  |.|. ...|...| ..|.  .| ||. . .|   . 
HHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-------TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR