7820

Species: Tetrahymena
Alias: PreTt07820, 7820, 852, TTHERM_00989300, 185.m00041
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7820.AA Protein None 1874 None Fasta, JSON
7820.kin_dom Protein Kinase Domain None 114 None Fasta, JSON
7820.NA RNA None 5625 None Fasta, JSON

Protein domain

Protein domains of 7820.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 7820.AA HisKA 472-539 33 2.1e-15 56.67 Pfam 1-69 (69) Show / Hide
Range on Protein: 472-539
Range on HMM: 1-69/69
Sequence Identity: 33% (23 aa)

QKKRMVASISHELRTPLNCSIGLLDLLLQDPKMPPDL-LQEYLMPALYSNRLLFNIVNDIIDFHQIDSG
.|....|..||||||||.  .|...||. .....|.  ..|||  .. . . . ...||. || .|..|
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 7820.AA HisKA 472-539 24 6.3e-15 56.83 SMART 1-89 (89) Show / Hide
Range on Protein: 472-539
Range on HMM: 1-89/89
Sequence Identity: 24% (22 aa)

QKKRMVASISHELRTPLNCSIGLLDLLLQ---------DPKMPPDLL------------QEYLMPALYSNRLLFNIVNDIIDFHQIDSG
.| ...|..||||||||.  .|...||.          .....|. .            .|||  .. . . . ...||. |. .|..|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 7820.AA HisK 586-699 39 3.4e-59 202.96 In-house 1-164 (164) Show / Hide
Range on Protein: 586-699
Range on HMM: 1-164/164
Sequence Identity: 39% (64 aa)

SDPQRIRQIVLNLLSNAVKYTFKG------FIRIEAVNYD--------------------------SQYIQIKVIDTGIGIKEESMNQIFEQFGRI----
|||.||.||..||.|||.|.|.||      .|.|.. ...                          ...||| |.|||.|..|| ...||..|| |    
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------QEEKVLETEGAGLGLTISMNLAKGVG------GNRGIDVQSTFGKGSTFSFFILKQ
        ...| . ..|.||||||. |||||.|      ||||| |||. ||||||||.|...
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 7820.AA HATPase_c 586-699 33 6.1e-30 106.43 Pfam 1-120 (120) Show / Hide
Range on Protein: 586-699
Range on HMM: 1-120/120
Sequence Identity: 33% (42 aa)

SDPQRIRQIVLNLLSNAVKYTFK-GFIRIEAVNYDSQYIQIKVIDTGIGIKE------ESMNQIFEQFGRIQE-EKVLETEG--AGLGLTISMNLAKGVG
 || |..|.|.||..||.|.| . | |....   |  ...| |.|.|.|| .      | ...||| |.|  .     ...|   ||||.|.  ... .|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG

GNRGIDVQSTFGKGSTFSFFILKQ
|   |.|.|. |.|.||.| . ..
GT--IWVESEPGGGTTFTFTLPLE

Kinase 7820.AA HATPase_c 586-700 26 5.4e-28 100.23 SMART 1-130 (130) Show / Hide
Range on Protein: 586-700
Range on HMM: 1-130/130
Sequence Identity: 26% (39 aa)

SDPQRIRQIVLNLLSNAVKYTFK--------------GFIRIEAVNYDSQYIQIKVIDTGIGIKE------ESMNQIFEQFGRIQE--------EKVLET
 || |.||...|||.||.|.| .              | |....        .| |.|.|.|| .      | ...||| |.|  .        ... ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

EG--AGLGLTISMNLAKGVGGNRGIDVQSTFGKGSTFSFFILKQE
.|   ||||.|. ....  ||   | |.      .||.| . ...
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 7820.AA REC 1036-1161 21 2.8e-26 94.56 SMART 1-150 (150) Show / Hide
Range on Protein: 1036-1161
Range on HMM: 1-150/150
Sequence Identity: 21% (35 aa)

KKILVVEDN----EFNLFLLK------KMLQSCNLE--------ADQAMNGQ-------EAIDKVIQSF-----TSQCTCRNGYKLIFMDIDMP------
..||.|.|.    . .. .|.      ..|.. . |        .|.| .|.       ||.... .        .    .. . ||.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IKNGYEATQEILKYCTSNDIKPPLISACSAYVGEEDKKQALKEGMTFFITKPIEMKVLQSVL
   .|.|....|             | ...|. .|||. .||. |.  .||||.... |. ..
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 7820.AA Response_reg 1038-1162 25 4.6e-16 60.11 Pfam 1-115 (115) Show / Hide
Range on Protein: 1038-1162
Range on HMM: 1-115/115
Sequence Identity: 25% (33 aa)

ILVVEDNEFNLFLLKKMLQ-SCNL-EADQAMNGQEAIDKVIQSFTSQCTCRNGYKLIFMDIDMPIKNGYEATQEI-LKYCTSNDIKPPLISACSAYVGEE
.|.|.|.. .. .|...|. .  . ... | .|.||....         ... . ||.|||.||  .|.|....|  .   . .  .| | .|.|.  |.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW---------QEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPII-MCTAHGDED

DKKQALKEGMTFFITKPIEMKVLQSVLK
|. .||. |.  .||||. .  |   ..
DAVEALQAGANDYITKPFDPDELHAAIR