Gene 7820 (Tetrahymena)
7820
Sequence
Protein domains of 7820.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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HisKA | 7820.AA | HisKA | 472-539 | 33 | 2.1e-15 | 56.67 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 472-539 Range on HMM: 1-69/69 Sequence Identity: 33% (23 aa) QKKRMVASISHELRTPLNCSIGLLDLLLQDPKMPPDL-LQEYLMPALYSNRLLFNIVNDIIDFHQIDSG .|....|..||||||||. .|...||. .....|. ..||| .. . . . ...||. || .|..| AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
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HisKA | 7820.AA | HisKA | 472-539 | 24 | 6.3e-15 | 56.83 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 472-539 Range on HMM: 1-89/89 Sequence Identity: 24% (22 aa) QKKRMVASISHELRTPLNCSIGLLDLLLQ---------DPKMPPDLL------------QEYLMPALYSNRLLFNIVNDIIDFHQIDSG .| ...|..||||||||. .|...||. .....|. . .||| .. . . . ...||. |. .|..| AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
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Kinase | 7820.AA | HisK | 586-699 | 39 | 3.4e-59 | 202.96 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 586-699 Range on HMM: 1-164/164 Sequence Identity: 39% (64 aa) SDPQRIRQIVLNLLSNAVKYTFKG------FIRIEAVNYD--------------------------SQYIQIKVIDTGIGIKEESMNQIFEQFGRI---- |||.||.||..||.|||.|.|.|| .|.|.. ... ...||| |.|||.|..|| ...||..|| | SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH --------QEEKVLETEGAGLGLTISMNLAKGVG------GNRGIDVQSTFGKGSTFSFFILKQ ...| . ..|.||||||. |||||.| ||||| |||. ||||||||.|... QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
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Kinase | 7820.AA | HATPase_c | 586-699 | 33 | 6.1e-30 | 106.43 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 586-699 Range on HMM: 1-120/120 Sequence Identity: 33% (42 aa) SDPQRIRQIVLNLLSNAVKYTFK-GFIRIEAVNYDSQYIQIKVIDTGIGIKE------ESMNQIFEQFGRIQE-EKVLETEG--AGLGLTISMNLAKGVG || |..|.|.||..||.|.| . | |.... | ...| |.|.|.|| . | ...||| |.| . ...| ||||.|. ... .| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG GNRGIDVQSTFGKGSTFSFFILKQ | |.|.|. |.|.||.| . .. GT--IWVESEPGGGTTFTFTLPLE |
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Kinase | 7820.AA | HATPase_c | 586-700 | 26 | 5.4e-28 | 100.23 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 586-700 Range on HMM: 1-130/130 Sequence Identity: 26% (39 aa) SDPQRIRQIVLNLLSNAVKYTFK--------------GFIRIEAVNYDSQYIQIKVIDTGIGIKE------ESMNQIFEQFGRIQE--------EKVLET || |.||...|||.||.|.| . | |.... .| |.|.|.|| . | ...||| |.| . ... .. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY EG--AGLGLTISMNLAKGVGGNRGIDVQSTFGKGSTFSFFILKQE .| ||||.|. .... || | |. .||.| . ... GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER |
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REC | 7820.AA | REC | 1036-1161 | 21 | 2.8e-26 | 94.56 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1036-1161 Range on HMM: 1-150/150 Sequence Identity: 21% (35 aa) KKILVVEDN----EFNLFLLK------KMLQSCNLE--------ADQAMNGQ-------EAIDKVIQSF-----TSQCTCRNGYKLIFMDIDMP------ ..||.|.|. . .. .|. ..|.. . | .|.| .|. ||.... . . .. . ||.||| || MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -IKNGYEATQEILKYCTSNDIKPPLISACSAYVGEEDKKQALKEGMTFFITKPIEMKVLQSVL .|.|....| | ...|. .|||. .||. |. .||||.... |. .. GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 7820.AA | Response_reg | 1038-1162 | 25 | 4.6e-16 | 60.11 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1038-1162 Range on HMM: 1-115/115 Sequence Identity: 25% (33 aa) ILVVEDNEFNLFLLKKMLQ-SCNL-EADQAMNGQEAIDKVIQSFTSQCTCRNGYKLIFMDIDMPIKNGYEATQEI-LKYCTSNDIKPPLISACSAYVGEE .|.|.|.. .. .|...|. . . ... | .|.||.... ... . ||.|||.|| .|.|....| . . . .| | .|.|. |. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW---------QEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--TPII-MCTAHGDED DKKQALKEGMTFFITKPIEMKVLQSVLK |. .||. |. .||||. . | .. DAVEALQAGANDYITKPFDPDELHAAIR |