Gene 7076 (Tetrahymena)

7076

Species: Tetrahymena
Alias: 7076, PreTt07076, 163.m00078, 3754.m00281, TTHERM_00920790, 286
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7076.AA Protein None 1213 None Fasta, JSON
7076.kin_dom Protein Kinase Domain None 119 None Fasta, JSON
7076.NA RNA None 3642 None Fasta, JSON

Protein domain

Protein domains of 7076.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 7076.AA HisKA 386-451 30 1.5e-17 65.53 SMART 1-89 (89) Show / Hide 
Range on Protein: 386-451
Range on HMM: 1-89/89
Sequence Identity: 30% (27 aa)

YQTQMIAQVSHELRTPLNCIMLMLEQLQQ-----------KINQELN------------KKYLRPSINSCNLLLSLINDILDLAQINAG
 ..|..| .||||||||. |....| ||            . . | .            ..||.  ... . ...||||.|||..| ||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 7076.AA HisKA 386-451 37 2e-17 63.67 Pfam 1-69 (69) Show / Hide 
Range on Protein: 386-451
Range on HMM: 1-69/69
Sequence Identity: 37% (26 aa)

YQTQMIAQVSHELRTPLNCIMLMLEQLQQ--KINQEL-NKKYLRPSINSCNLLLSLINDILDLAQINAG
 ..|..| .||||||||. |....| ||   . . |   ..||   ... . ...||||.||...| ||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 7076.AA HisK 498-616 42 5e-59 202.43 In-house 1-164 (164) Show / Hide 
Range on Protein: 498-616
Range on HMM: 1-164/164
Sequence Identity: 42% (69 aa)

SDPNRLRQILINLIGNSLKFTRKG------SITLKTTLINTQPV------------------------RMDIQVIDTGIGIPQEKQEEIFNQFNKIQD--
|||||..|||||||.|.|||| ||      .|..| ..||||..                           |.|.|||.|.|.|.|..||..|..|.|  
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------NQNKQLNSSGCGLGLNISNQLAKGISING-----QGIRVQSQVGQGSTFSFYLEDK
        .|||..|..||||||.|.|.||||.. ..     .|| |||.||.|||||||....
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 7076.AA HATPase_c 498-616 30 6e-25 89.05 Pfam 1-120 (120) Show / Hide 
Range on Protein: 498-616
Range on HMM: 1-120/120
Sequence Identity: 30% (39 aa)

SDPNRLRQILINLIGNSLKFTRK-GSITLKTTLINTQPVRMDIQVIDTGIGIPQ------EKQEEIFNQFNKIQDNQNKQLNSSG--CGLGLNISNQLAK
 ||.||.|.. ||..|..|.|.. | ||.. .  .    .  |.|.|.|.|||       |... ||  | .  .      ...|   |||| |......
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVE

GISINGQGIRVQSQVGQGSTFSFYLEDK
        |.|.|..|.|.||.|.|  .
QHGGT---IWVESEPGGGTTFTFTLPLE
Kinase 7076.AA HATPase_c 498-617 26 1.3e-23 85.73 SMART 1-130 (130) Show / Hide 
Range on Protein: 498-617
Range on HMM: 1-130/130
Sequence Identity: 26% (39 aa)

SDPNRLRQILINLIGNSLKFTRK--------------GSITLKTTLINTQPVRMDIQVIDTGIGIPQ------EKQEEIFNQFNKIQDNQ------NKQL
 ||.||||.|.||..|..|.| .              | ||..            |.|.|.|.|||.      |... ||  | .  |..      ..  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NSSG--CGLGLNISNQLAKGISINGQGIRVQSQVGQGSTFSFYLEDKQ
...|   |||| |......        |.|.      .||.|.|  ..
KYGGGLTGLGLSICKRIVEQHGGT---IWVE------TTFTFTLPLER
REC 7076.AA REC 1063-1190 22 1.4e-18 69.0 SMART 1-150 (150) Show / Hide 
Range on Protein: 1063-1190
Range on HMM: 1-150/150
Sequence Identity: 22% (37 aa)

FRILIVDDN----QFNVQALK------LFLSTYFYS-------SIDVAFDGE-------QAIEKVQNYL----NLNSECGCREYDLIFMDIEMP------
 |||||||.    . . ..|.      ..|.   |         .|.| |||       .|.|..|.         .     ..|||.|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-LLDGFQTSIQIHKILSDKINNPKTVIIASSANDEYQESNLKKYKIDYQIEKPVKKKQLEQVL
  .||...  .|             .|. .. .||       .   |  | ||.. ..| ...
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 7076.AA Response_reg 1065-1191 23 7.7e-14 52.13 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1065-1191
Range on HMM: 1-115/115
Sequence Identity: 23% (31 aa)

ILIVDDNQFNVQALKLFLS-TYFYSSIDVAFDGEQAIEKVQNYLNLNSECGCREYDLIFMDIEMPLLDGFQTSIQI-HKIL-SDKINNPKTVIIASSAND
.|||||.. . ..|. .|   . |.....| |||.|.|..|..           .|||.|||.|| .||...  .| ..   ..    .. ... . ...
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH----------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAHGDE

EYQESNLKKYKIDYQIEKPVKKKQLEQVLI
.. .  | .. ... | ||... .| . . 
DDAVEAL-QAGANDYITKPFDPDELHAAIR