Gene 6390 (Tetrahymena)

6390

Species: Tetrahymena
Alias: 1025, TTHERM_00526520, PreTt06390, 6390, 66.m00189, 3722.m00047
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6390.AA Protein None 1434 None Fasta, JSON
6390.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
6390.NA RNA None 4305 None Fasta, JSON

Protein domain

Protein domains of 6390.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 6390.AA HisKA 667-732 22 2.1e-12 48.48 SMART 1-89 (89) Show / Hide 
Range on Protein: 667-732
Range on HMM: 1-89/89
Sequence Identity: 22% (20 aa)

YKNEMLSSITHNLKTPLNAVMIMIESAIL-----------SNSLQQA------------QKQLQLAQNSGRLLLYMINDLLDYSRLSSS
 |...|... | |.|||.|.. ..| .               . .|.            .. |. .|.... .. .||||||.||. . 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 6390.AA HisKA 667-732 28 5.2e-12 44.85 Pfam 1-69 (69) Show / Hide 
Range on Protein: 667-732
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

YKNEMLSSITHNLKTPLNAVMIMIESAIL--SNSLQQ-AQKQLQLAQNSGRLLLYMINDLLDYSRLSSS
 |...|... | |.|||.|.. ..| .      . .| ... |. .|.... .. .||||||.||. . 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 6390.AA HisK 781-896 31 3e-51 176.56 In-house 1-164 (164) Show / Hide 
Range on Protein: 781-896
Range on HMM: 1-164/164
Sequence Identity: 31% (51 aa)

NDKQRIEQVLLNLCQNALKFTFQG------FVKINVF----------------EDETR--------PNDLFFQVQDSGLGISDEAKKNLFKIYGN-----
.|..|| |.|.|| .||||||..|      ..||.|                 .....        .| . ..|||.| |...| .|..||..||     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----MIINSQN--KRHGVGLGLAVCRKLVSQLGSE------KVIQIESFKGKGSSFTFSIYKK
     . ....   ..||.||||..|..|. .||.|      . ||..| .||||.|.| ||..
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 6390.AA HATPase_c 781-896 30 2.1e-22 80.2 Pfam 1-120 (120) Show / Hide 
Range on Protein: 781-896
Range on HMM: 1-120/120
Sequence Identity: 30% (39 aa)

NDKQRIEQVLLNLCQNALKFTFQ-GFVKINVFEDETRPNDLFFQVQDSGLGISD------EAKKNLFKIYGNMII-NSQNKRHG--VGLGLAVCRKLVSQ
.|  |..||..||  ||.|.| . | ... | .|.   ... ..|.|.| ||..      |   ..|  ..      .  |. |   ||||..||..| |
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

LGSEKVIQIESFKGKGSSFTFSIYKK
.| .  |..||  |.|. ||| . ..
HGGT--IWVESEPGGGTTFTFTLPLE
Kinase 6390.AA HATPase_c 781-897 23 1.9e-20 75.18 SMART 1-130 (130) Show / Hide 
Range on Protein: 781-897
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

NDKQRIEQVLLNLCQNALKFTFQ--------------GFVKINVFEDETRPNDLFFQVQDSGLGISD------EAKKNLFKIYGNMII--------NSQN
.|  |..|||.|| .||.|.| .              | ... |           ..|.|.| ||..      |  ...|  ..            ..  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

KRHG--VGLGLAVCRKLVSQLGSEKVIQIESFKGKGSSFTFSIYKKH
|. |   ||||..|...| |.| .  |..|      . |||.. ...
KYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 6390.AA REC 1305-1423 24 4.2e-30 107.26 SMART 1-150 (150) Show / Hide 
Range on Protein: 1305-1423
Range on HMM: 1-150/150
Sequence Identity: 24% (40 aa)

TNLLIVDDT----IFNIMALK------TILKNVNNL-------VFDEAYNGQ-------QAIEKVLQKK------------NYDLIFMDINMP-------
 . |||||       . ..|.       .|.  .         | ||| .|.       .|.|.. ...            ..|||.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

VLDGFEATQSITRLIEQKKIPYTTIIIVSAFNDESDRQRSFQSGAKAHIDKPVTLDNIYKAI
 .||.|... |             ||...|..||.||.| ...|| . | ||.... . ..|
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 6390.AA Response_reg 1307-1424 37 1.4e-28 104.9 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1307-1424
Range on HMM: 1-115/115
Sequence Identity: 37% (45 aa)

LLIVDDTIFNIMALKTILKNVNNL-VFDEAYNGQQAIEKVLQKKNYDLIFMDINMPVLDGFEATQSI-TRLI-EQKKIPYTTIIIVSAFNDESDRQRSFQ
.|||||   . ..|..||..   . | .||..|..|.|.. |.. .|||.|||||| .||.|... |  ..   |     | ||...|..||.|... .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDAVEALQ

SGAKAHIDKPVTLDNIYKAIK
 ||  .| ||. .| ...||.
AGANDYITKPFDPDELHAAIR