Gene 5989 (Tetrahymena)
5989
Sequence
Protein domains of 5989.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 5989.AA | HisK | 637-778 | 29 | 2.2e-43 | 150.45 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 637-778
Range on HMM: 1-164/164
Sequence Identity: 29% (52 aa)
TDKQKIQQILIHLIHNAIKFSKQNA-----SICVSVSLIQDE---------------------LTKQKIVCINVADIGVGMDEEEQLKLRQLLDNI----
.|...|.||||.|| ||.|| .... .|...|..|... | ......| | | |.||.||.| |. ... ||
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH
------YQSQKVSKHSSGFGFGLTISNILAKKLYSTHNSFYEGNAQASYIQKEEYQPGIHFTSKKNVGSEFRFYINAT
.. |. . ...| |.||||.|.|||.| ..|| |. .. || . |....||.| |||. .
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHN------------QN--GNRGIQVQSEVGKGSTFSFYIYNN
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| Kinase | 5989.AA | HATPase_c | 637-778 | 17 | 4.9e-11 | 40.66 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 637-778 Range on HMM: 1-120/120 Sequence Identity: 17% (27 aa) TDKQKIQQILIHLIHNAIKFSKQNASICVSVSLIQDELTKQKIVCINVADIGVGMDEEEQLKLRQLLDNIYQSQKVSK--------------HSSG--FG .| ..|.. |. ||||..... | |.|. |.| | | |.|...|. . ..... ..| .| GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD------DHVRITVEDNGPGIPPEMH----------SIAEDIPRIFEPFYRTDPDSRRKYGGGLTG FGLTISNILAKKLYSTHNSFYEGNAQASYIQKEEYQPGIHFTSKKNVGSEFRFYINAT .||.|.. ..... | .|.. . |..|.|.. . LGLYICRRIVEQHGGT--IWVESEP--------------------GGGTTFTFTLPLE |
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| Kinase | 5989.AA | HATPase_c | 637-779 | 15 | 2.5e-10 | 41.53 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 637-779 Range on HMM: 1-130/130 Sequence Identity: 15% (27 aa) TDKQKIQQILIHLIHNAIKFSKQ-------------NASICVSVSLIQDELTKQKIVCINVADIGVGMDE----EEQLKLRQLLDNIYQSQK-------- .| ..|.|. |. ||||.... . | |.|. .| |.| |.|... . .. .... |. . GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------RITVEDNGPGIPPEMHKSI-EDIPRIFEPFYRTDDSPSRMCPD -VSKHSSG--FGFGLTISNILAKKLYSTHNSFYEGNAQASYIQKEEYQPGIHFTSKKNVGSEFRFYINATD | ..| .| ||.|.. ..... | .| ..|.|.. . SRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE--------------------------TTFTFTLPLER |
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| REC | 5989.AA | REC | 963-1095 | 23 | 3.7e-28 | 100.8 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 963-1095 Range on HMM: 1-150/150 Sequence Identity: 23% (40 aa) YKILIVDDE----MMNIFGLK------MMFKILGVDQGL-----LLQANNGE-------EALNIFKQNI-----LNENKQSQ-IKLIVMDINMP------ ..||||||. .. .|. .... .| .. . .| .|| |||...... .. ||. . ||.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -IMDGIQATIEINNFMNQLKGQNTDFLETNIVACSSYDDYDTKQECMNAGMISYISKPCNKEQLTHII ||||... .| |......|| ....... ||. ||.||.. |.| . | GGMDGIELCRRIR----------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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| Response_reg | 5989.AA | Response_reg | 965-1096 | 29 | 2.2e-18 | 68.43 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 965-1096 Range on HMM: 1-115/115 Sequence Identity: 29% (40 aa) ILIVDDEMMNIFGLKMMFK-ILGVDQGLLLQANNGEEALNIFKQNILNENKQSQIKLIVMDINMPIMDGIQATIEI-NNFMNQLKGQNTDFLETNIVACS .|||||. . ||. ... | | .|||||... .. .. ||.|||||| |||.... .| . . . | |..|. VLIVDDHPLMREGLRQILEQKEGY--EVVAEADDGEEALEWW--------QEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ--------TPIIMCT SYDDYDTKQECMNAGMISYISKPCNKEQLTHIIQ ...| |...|.. ||. ||.||.....| .|. AHGDEDDAVEALQAGANDYITKPFDPDELHAAIR |
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