Gene 5265 (Tetrahymena)

5265

Species: Tetrahymena
Alias: 5265, 1022, 36.m00229, TTHERM_00348530, PreTt05265, 3703.m00091
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
5265.AA Protein None 1765 None Fasta, JSON
5265.kin_dom Protein Kinase Domain None 166 None Fasta, JSON
5265.NA RNA None 5298 None Fasta, JSON

Protein domain

Protein domains of 5265.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 5265.AA HisKA 846-908 26 1.3e-08 32.99 Pfam 1-69 (69) Show / Hide 
Range on Protein: 846-908
Range on HMM: 1-69/69
Sequence Identity: 26% (18 aa)

YKDEMLATVTHNLKTPLNSMILLINKLLK-----KEK-RNKELKIISQSSNMLLSMIMDILDYQCIKRK
 | ..||.. | |.|||.......  |..      |. | . |..| .... ....| |.||.  |   
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 5265.AA HisKA 846-908 20 2.5e-08 34.9 SMART 1-89 (89) Show / Hide 
Range on Protein: 846-908
Range on HMM: 1-89/89
Sequence Identity: 20% (18 aa)

YKDEMLATVTHNLKTPLNSMILLINKLLK--------------KEKR------------NKELKIISQSSNMLLSMIMDILDYQCIKRK
 |...||.. | |.|||.......  |..               |.|             . |..| .... ....| |.||.  |   
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 5265.AA HisK 957-1122 30 1.1e-54 188.04 In-house 1-164 (164) Show / Hide 
Range on Protein: 957-1122
Range on HMM: 1-164/164
Sequence Identity: 30% (61 aa)

QDMDRIKQILNNLVGNAIKFTKKG------SITIIIGYDTTYSNDSIKKEQNSQDQLKDENNTPELQANNNSIKTDAEKSVKLNNYQRIFQNN-------
.|  |||||| ||..||.|||.||      .|.|.. .. |..|  | |. ||                               .... .|.|       
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN--I-KY-NS-------------------------------IFIQKIQENMVQEQLQ

--GVISIQVKDTGSGIDHSLQQNLFKIFA-----------THDHNDGST-KHGVGLGLTVCRKLVKLIGPR------RSLLLDSTPGIGSSFTFFIYQN
  ..| |.|.||| |.....|...||.|            |..|....  .||.|||||.|..|.|..||.      |.. . |..|.||.|.|.||.|
QKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 5265.AA HATPase_c 957-1122 23 4.2e-23 82.63 Pfam 1-120 (120) Show / Hide 
Range on Protein: 957-1122
Range on HMM: 1-120/120
Sequence Identity: 23% (41 aa)

QDMDRIKQILNNLVGNAIKFTKK-GSITIIIGYDTTYSNDSIKKEQNSQDQLKDENNTPELQANNNSIKTDAEKSVKLNNYQRIFQNNGVISIQVKDTGS
 | ||..|.. |||.||||.|.. | ||. .  |                                                      . ..|.|.|.| 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----------------------------------------------------DHVRITVEDNGP

GIDH------SLQQNLFKIFATHDH-NDGSTKHG--VGLGLTVCRKLVKLIGPRRSLLLDSTPGIGSSFTFFIYQN
||.        .....|  | . |   . .   |   ||||..||..|.. | .  . ..|.|| |. ||| .   
GIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGGT--IWVESEPGGGTTFTFTLPLE
Kinase 5265.AA HATPase_c 957-1123 17 1.3e-20 75.67 SMART 1-130 (130) Show / Hide 
Range on Protein: 957-1123
Range on HMM: 1-130/130
Sequence Identity: 17% (35 aa)

QDMDRIKQILNNLVGNAIKFTKK--------------GSITIIIGYDTTYSNDSIKKEQNSQDQLKDENNTPELQANNNSIKTDAEKSVKLNNYQRIFQN
 | ||..|.|.||..||||.|..              | ||. .                                                        
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

NGVISIQVKDTGSGIDH------SLQQNLFKIFATHDH--------NDGSTKHG--VGLGLTVCRKLVKLIGPRRSLLLDSTPGIGSSFTFFIYQNL
    .|.|.|.| ||.        .....|  | . |         .. .   |   ||||..|...|.. | .  . ..      . ||| .   .
----RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 5265.AA REC 1641-1758 23 1e-26 95.96 SMART 1-150 (150) Show / Hide 
Range on Protein: 1641-1758
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

INALIVDDT----PFNIFVLK------SFFQNCKNI-------KFSQAFDGK-------EAFELYKEN-------------KYDLVFMDLNMP-------
.. |||||     | .  .|.       ...               .| ||.       ||.|| .|.             ..||..||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGFESITLIRQFEHQNNLKESIIFAVTAQDQIKDIQKCIDCGANGHIPKPVKLSLLYSSL
 |||.| .  ||            | ..|| |.  |...... ||.. |.||...  |   .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 5265.AA Response_reg 1643-1759 33 2.8e-25 93.14 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1643-1759
Range on HMM: 1-115/115
Sequence Identity: 33% (40 aa)

ALIVDDTPFNIFVLKSFFQNCKNI-KFSQAFDGKEAFELYKENKYDLVFMDLNMPIMDGFESITLI-RQFE-HQNNLKESIIFAVTAQDQIKDIQKCIDC
 ||||| | .  .|. ....   . .   | ||.|| |. .|...||..||.||| |||.| .. | || . .|       | ..|| ... |...... 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDAVEALQA

GANGHIPKPVKLSLLYSSLY
|||..|.||...  |.  . 
GANDYITKPFDPDELHAAIR