Gene 4106 (Tetrahymena)

4106

Species: Tetrahymena
Alias: 80.m00152, PreTt04106, 691, 3675.m00050, TTHERM_00584990, 4106
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
4106.AA Protein None 1748 None Fasta, JSON
4106.kin_dom Protein Kinase Domain None 96 None Fasta, JSON
4106.NA RNA None 5247 None Fasta, JSON

Protein domain

Protein domains of 4106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 4106.AA HisKA 963-1051 25 1.4e-10 39.81 Pfam 1-69 (69) Show / Hide 
Range on Protein: 963-1051
Range on HMM: 1-69/69
Sequence Identity: 25% (23 aa)

YKMKMFASLSHELRTPLNCTISMLEGLEQFITDPQLIDEQINIFKFINLIKLFHPAQKVKDFFYATLHSQKLLLNQINDILDFAQIDSG
 | ...|..||||||||.  . ..| |.    .. | .||.                 .....   ... . ....|||.|||..|..|
AKRQFLANMSHELRTPLTAIRGYAELLQD---YTDLDPEQM-----------------RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 4106.AA HisKA 963-1051 20 2.8e-07 31.44 SMART 1-89 (89) Show / Hide 
Range on Protein: 963-1051
Range on HMM: 1-89/89
Sequence Identity: 20% (20 aa)

YKMKMFASLSHELRTPLNCTISMLEGLEQ-----------FITDPQLIDEQINIFKFINLIKLFHPAQKVKDFFYATLHSQKLLLNQINDILDFAQIDSG
 | ...|..||||||||.  . ..| |.              ...|. ..                   .....   ... . ....|||.||...|..|
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRR-E----------FNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 4106.AA HisK 1098-1240 31 2.9e-50 173.3 In-house 1-164 (164) Show / Hide 
Range on Protein: 1098-1240
Range on HMM: 1-164/164
Sequence Identity: 31% (57 aa)

SDQNRIRQILLNFLSNSLKFTPENG-----TIKIIAEPMF-----------INETNRV--------QKYIRLVVQDTGIGMKPETVQNIFNAFN------
||.|||.|||.|..||.|||| ..|     .|||..| .            |.. .          ...|.  |||||.||..|....||..|.      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----KTEYESEGMNSQGCGLGLAISQSISKGLCTTQNQNSTQFNILSEYQIPQNWIGIQ---VESQYGQGSSFSFIIQDM
     ... ...  |..||||||.|.... |||  ..||               |  | .   |.|..|.||.||| |.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQ---------------N--GNRGIQVQSEVGKGSTFSFYIYNN
Kinase 4106.AA HATPase_c 1098-1193 28 2.5e-22 79.95 Pfam 1-95 (120) Show / Hide 
Range on Protein: 1098-1193
Range on HMM: 1-95/120
Sequence Identity: 28% (30 aa)

SDQNRIRQILLNFLSNSLKFTPENGTIKIIAEPMFINETNRVQKYIRLVVQDTGIGMKP------ETVQNIFNAFNKTEYESEGMNSQG--CGLGLAISQ
 |..|..|...|...|..|.|||.|.|.. ...           ..|..|.|.|.|. |      | ...|| .| .|.  |   ...|   ||||.|..
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICR

SISK
 |..
RIVE
Kinase 4106.AA HATPase_c 1098-1214 23 1.1e-20 76.0 SMART 1-130 (130) Show / Hide 
Range on Protein: 1098-1214
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

SDQNRIRQILLNFLSNSLKFTPE-------------NGTIKIIAEPMFINETNRVQKYIRLVVQDTGIGMKP------ETVQNIFNAFNKTEYE------
 |..|.||.|.| |.|..|.|||             .|.|.. ..              |..|.|.|.|. |      | ...|| .| .|. .      
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCP

-SEGMNSQG--CGLGLAISQSISKGL---CTTQNQNSTQFNILSEYQI
 |   ...|   ||||.|...|.. .    . .    | | .    ..
DSRSRKYGGGLTGLGLSICKRIVEQHGGTIWVE----TTFTFTLPLER
Kinase 4106.AA HATPase_c 1221-1240 40 10.395096 1.23 Pfam 101-120 (120) Show / Hide 
Range on Protein: 1221-1240
Range on HMM: 101-120/120
Sequence Identity: 40% (8 aa)

IQVESQYGQGSSFSFIIQDM
|.|||. |.|. |.| .   
IWVESEPGGGTTFTFTLPLE
REC 4106.AA REC 1574-1708 22 2.5e-23 84.74 SMART 1-150 (150) Show / Hide 
Range on Protein: 1574-1708
Range on HMM: 1-150/150
Sequence Identity: 22% (37 aa)

ASILIVDDN----QFNILALS------RMLQQFFNAP-------IDKAFDGK-------QAFEKICYRYQQNKPIQSCPKCLRYEIVFMDIEMP------
 .||||||.    . .  .|.      |.|..    .       .| | ||.       .|.|..    ...    .     .. ...|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-ILNGYEVMKELTDFFHEHKIHKEDFPYIIACTAHGGDQEQVRAKNSGFDDYISKPIMRNDIQKLL
  ..|.|. ...                ||..|||....  |||  .| ||||.||. ...... .
GGMDGIELCRRIR--------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 4106.AA Response_reg 1576-1709 26 4.6e-16 60.12 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1576-1709
Range on HMM: 1-115/115
Sequence Identity: 26% (36 aa)

ILIVDDNQFNILALSRMLQQFFNA-PIDKAFDGKQAFEKICYRYQQNKPIQSCPKCLRYEIVFMDIEMPILNGYEVMKEL-TDFFHEHKIHKEDFPYIIA
.|||||.. .  .| ..|.|      .. | ||..| |..    |...          . ...|||.|| ..|.|. ...      ...      . ||.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW----QEHH----------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ------TPIIM

CTAHGGDQEQVRAKNSGFDDYISKPIMRNDIQKLLC
||||| ..  |.|   | .|||.||. .... . . 
CTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR