Gene 3312 (Tetrahymena)
3312
Sequence
Protein domains of 3312.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 3312.AA | HisK | 779-965 | 24 | 2e-44 | 153.88 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 779-965 Range on HMM: 1-164/164 Sequence Identity: 24% (52 aa) HDQRRLLQILVNLISNSLKFTFKG------KIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQEIIQSNNN |..|. |||.|||||.||||.|| .|..... ...||| .| | | .|....... . . SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNI----------------KY-N--S----------------IFIQKIQEN--M-V-- LIDKLADKKKLFKKEKHIRFTVVDSGIGMSHQKLQKLKRMLF--------------KKEIFNIQNSSGLGLTMCYSLIKQIGCQH-----THLEIQSEEN . . .......|...| |.|.||......|.. |. .....| |. |||||.|..|.|..|..| ....|||.. Q-------E-QLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVG IGTKFSFTIQQF .|..||| |... KGSTFSFYIYNN |
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Kinase | 3312.AA | HATPase_c | 779-965 | 15 | 1.7e-14 | 52.65 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 779-965 Range on HMM: 1-120/120 Sequence Identity: 15% (32 aa) HDQRRLLQILVNLISNSLKFTFK-GKIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQEIIQSNNNLIDKL |..|| |.. ||..|..|.| . |.|.. ... GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD----------------------------------------------------------------- ADKKKLFKKEKHIRFTVVDSGIGMSH------QKLQKLKR-------MLFKKEIFNIQNS--SGLGLTMCYSLIKQIGCQHTHLEIQSEENIGTKFSFTI |.|.|| |.|.|.. ...... . .||||..|. ...| | . ....||.. ||.|.||. ----------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD----SR-RKYGGGLTGLGLYICRRIVEQHGGT---IWVESEPGGGTTFTFTL QQF PLE |
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Kinase | 3312.AA | HATPase_c | 779-966 | 13 | 2.4e-12 | 48.26 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 779-966 Range on HMM: 1-130/130 Sequence Identity: 13% (29 aa) HDQRRLLQILVNLISNSLKFTFK--------------GKIELIIDTPSDENNINLGSMHMFQNNQISTGRYSNSPSSNKNKQLDTRSLQSNLLFKNCKNQ |..|| |.| ||..|..|.| . |.|.. .. GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------------------------------------------------- EIIQSNNNLIDKLADKKKLFKKEKHIRFTVVDSGIGMSH------QKLQKLKRMLFKKE----------IFNIQNS--SGLGLTMCYSLIKQIGCQHTHL |.|| |.|.|.. ...... .. . .||||. | ....| | . . --------------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT---I EIQSEENIGTKFSFTIQQFY ... |.|.||. WVE------TTFTFTLPLER |
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REC | 3312.AA | REC | 1518-1638 | 21 | 2.1e-21 | 78.33 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1518-1638 Range on HMM: 1-150/150 Sequence Identity: 21% (35 aa) KHVLVVDDTI---YNIISLKI------FFRNVQNLN--------IEEAYNGR-------DALQKYQENAINGI--------FYDYIFMDIEMP------- ...|.||| | . .. .. ..|| .|. .||.. ||. ... .| |.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG IMDGLECIKHIREFETANSLKKSIIITVTAYEREQQEVILAGANALIAKPIQKDKFLQTL |||.| ...|| . |..| . | .. . |||.. | ||.. . .|... GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
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Response_reg | 3312.AA | Response_reg | 1520-1639 | 33 | 2.1e-16 | 61.33 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1520-1639 Range on HMM: 1-115/115 Sequence Identity: 33% (41 aa) VLVVDDTIYNIISLKIFFRNVQNL-NIEEAYNGRDALQKYQENAINGIFYDYIFMDIEMPIMDGLECIKHI-REFETANSLKKSIIITVTAYER--EQQE ||.||| . |. .... . ...||..|..||.. ||. .| |.|||.|| ||||| .. | |. . . || .||.. .| VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDEDDAVE VILAGANALIAKPIQKDKFLQTLR .. |||| |.||. .|. .. .| ALQAGANDYITKPFDPDELHAAIR |