Gene 3209 (Tetrahymena)
3209
Sequence
Protein domains of 3209.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
HisKA | 3209.AA | HisKA | 740-814 | 32 | 1e-06 | 26.15 | Pfam | 1-69 (69) | Show / Hide |
Range on Protein: 740-814 Range on HMM: 1-69/69 Sequence Identity: 32% (24 aa) YKIKMLSSISHELKTPLNCCMGMLDDVLNLISNENFGDLEISQKIRESLEPAQQSNQLLLYMIRDLIDLGTFELV | ..|...||||.|||. .|... .. ..|| | .|| || .|.. | .. .|.|| |. | AKRQFLANMSHELRTPLTAIRGYAELLQD------YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG |
|||||||||
HisKA | 3209.AA | HisKA | 740-814 | 25 | 5e-05 | 21.42 | SMART | 1-89 (89) | Show / Hide |
Range on Protein: 740-814 Range on HMM: 1-89/89 Sequence Identity: 25% (24 aa) YKIKMLSSISHELKTPLNCCMGMLDDVLNLISNENF--------GDLEISQK-----------IRESLEPAQQSNQLLLYMIRDLIDLGTFELV | ..|...||||.|||. .|... . ... .|| | .|| || .|.. . .. .|.|| || | AKRQFLANMSHELRTPLTAIRGYAE-----LLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG |
|||||||||
Kinase | 3209.AA | HisK | 862-982 | 31 | 4.2e-51 | 176.08 | In-house | 1-164 (164) | Show / Hide |
Range on Protein: 862-982 Range on HMM: 1-164/164 Sequence Identity: 31% (51 aa) SDENRVRSIVVNFLTNSLKFTQRNG-----KITVKAELTG--------------------------NNNAKISVEDNGIGIPQKKLSEIFKFYNKSD--- ||.||.. |..|...|.||||| .| .|..|.|. .|. .|||.| |.|.|.... .|||.... | SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH -----MFISKNQ--ITQGIGIGLSVSYKLAQGLTIEEY--KNQPIQVKSEEKKGSIFCFVLKNQ .|. .|. ..|.|.||.....||.|| |.. .|..|||.||..|||.| |.. |. QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN |
|||||||||
Kinase | 3209.AA | HATPase_c | 862-982 | 27 | 3e-25 | 90.12 | Pfam | 1-120 (120) | Show / Hide |
Range on Protein: 862-982 Range on HMM: 1-120/120 Sequence Identity: 27% (36 aa) SDENRVRSIVVNFLTNSLKFTQRNGKITVKAELTGNNNAKISVEDNGIGIPQ------KKLSEIFKFYNKSDMFISKNQITQG--IGIGLSVSYKLAQGL |..|.. .| |...|..|.|. .|.|||... .. .. |.|||||.||| .... || . ..| | . ..| |.||........ . GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH TIEEYKNQPIQVKSEEKKGSIFCFVLKNQ . |.| ||...|. | | |. . GGT------IWVESEPGGGTTFTFTLPLE |
|||||||||
Kinase | 3209.AA | HATPase_c | 862-983 | 23 | 5.6e-23 | 83.59 | SMART | 1-130 (130) | Show / Hide |
Range on Protein: 862-983 Range on HMM: 1-130/130 Sequence Identity: 23% (35 aa) SDENRVRSIVVNFLTNSLKFTQR-------------NGKITVKAELTGNNNAKISVEDNGIGIPQ------KKLSEIFKFYNKSDMFI------SKNQIT |..|.| .. | |.|..|.|. .|.|||... |.|||||.|||. .... || . . | .. |... . GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY QG--IGIGLSVSYKLAQGLTIEEYKNQPIQVKSEEKKGSIFCFVLKNQD .| |.|||.. .... . . |.| . |.| |. . GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER |
|||||||||
REC | 3209.AA | REC | 1275-1397 | 26 | 3.3e-33 | 117.56 | SMART | 1-150 (150) | Show / Hide |
Range on Protein: 1275-1397 Range on HMM: 1-150/150 Sequence Identity: 26% (44 aa) GQILIVDDI----QFNLLMLS------NLLKRYQMK--------VDLAHDGQ-------EAVNKVQEK--------YQKQKETYQIIFMDIQMP------ |||||| . .. ||. .||.. . || | ||. ||....||. |.| ...|.|||.|| MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED -IMDGFQATKEIRKFLQQKNASQIPIIAVSAFGDQQFKEQSKKVGMTDYIEKPVQTIKLDKAF |||......|| |||...|..| . ... ..|. ||| ||.. | .. GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI |
|||||||||
Response_reg | 3209.AA | Response_reg | 1277-1398 | 32 | 9.2e-29 | 105.59 | Pfam | 1-115 (115) | Show / Hide |
Range on Protein: 1277-1398 Range on HMM: 1-115/115 Sequence Identity: 32% (40 aa) ILIVDDIQFNLLMLSNLLK-RYQM-KVDLAHDGQEAVNKVQEKYQKQKETYQIIFMDIQMPIMDGFQATKEIRKFLQ-QKNASQIPIIAVSAFGDQQFKE .||||| . .. | ..|. .... .|..| ||.||....||. . .|.|||.|| |||......||. .. . .|||...|.|| . .. VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAHGDEDDAV QSKKVGMTDYIEKPVQTIKLDKAFL . ..|. ||| ||. .| .| EALQAGANDYITKPFDPDELHAAIR |