Gene 30008 (Tetrahymena)

30008

Species: Tetrahymena
Alias: 138.m00128, PreTt30008, TTHERM_00813020, 902, 30008
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
30008.AA Protein None 1555 None Fasta, JSON
30008.kin_dom Protein Kinase Domain None 117 None Fasta, JSON
30008.NA RNA None 4668 None Fasta, JSON

Protein domain

Protein domains of 30008.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 30008.AA HisKA 714-781 28 2e-09 35.83 Pfam 1-69 (69) Show / Hide 
Range on Protein: 714-781
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

FKLKILSSISHELRTPLNCSMSMLQMLLQSDHISEAL-KQDYLQPAFFNNQLLYFIINDILDYAQISQN
 | . |...||||||||.  . ....|. ... ..    ..||. .    | .  .|||.||...| ..
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 30008.AA HisKA 714-781 23 1.4e-08 35.77 SMART 1-89 (89) Show / Hide 
Range on Protein: 714-781
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

FKLKILSSISHELRTPLNCSMSMLQMLLQ----------SDHISEALK-----------QDYLQPAFFNNQLLYFIINDILDYAQISQN
 | . |...||||||||.  . ....|.           .|  .| ..           ..||. .    . .  .|||.||...| ..
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 30008.AA HisK 828-944 36 8.3e-57 195.04 In-house 1-164 (164) Show / Hide 
Range on Protein: 828-944
Range on HMM: 1-164/164
Sequence Identity: 36% (60 aa)

SDQERIKQVLINLVSNAIKYTNSG------YINVNASLS------------------------PDQKDLIEISVEDTGCGIPPHLHNIIFDYMDNPG---
||. ||||.||||.|||.|.|. |      || ......                        ..||.||.|||.|||||.|... . ||.   |     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

--------KKKKELNSTGAGLGLTISQKIVKGLS------ENKGISLQSEVGVGSKFTFYVKNR
        ...| .|. |.||||||.....|||.       |.||..|||||.||.|.||. |.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 30008.AA HATPase_c 828-944 34 4.3e-25 89.56 Pfam 1-120 (120) Show / Hide 
Range on Protein: 828-944
Range on HMM: 1-120/120
Sequence Identity: 34% (43 aa)

SDQERIKQVLINLVSNAIKYTNS-GYINVNASLSPDQKDLIEISVEDTGCGIPP------HLHNIIFDYMDNPGKKKKELNSTG--AGLGLTISQKIVKG
 |..|..||. |||.||||.| . | | | ..  .   | ..|.|||.|.||||      .. . ||.     ..     .. |   ||||.|...||. 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

LSENKGISLQSEVGVGSKFTFYVKNR
.     |...||.| |..|||... .
HGGT--IWVESEPGGGTTFTFTLPLE
Kinase 30008.AA HATPase_c 828-945 25 2.8e-21 77.91 SMART 1-130 (130) Show / Hide 
Range on Protein: 828-945
Range on HMM: 1-130/130
Sequence Identity: 25% (38 aa)

SDQERIKQVLINLVSNAIKYTNS--------------GYINVNASLSPDQKDLIEISVEDTGCGIPP------HLHNIIFDYMDNPGK-------KKKEL
 |..|..|||.||..||||.| .              | | | ..         .|.|||.|.||||      .. . ||. .   ..       . .. 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NSTG--AGLGLTISQKIVKGLSENKGISLQSEVGVGSKFTFYVKNRD
.. |   ||||.|...||. .     |...      ..|||... . 
KYGGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
REC 30008.AA REC 1421-1546 20 4.9e-18 67.17 SMART 1-150 (150) Show / Hide 
Range on Protein: 1421-1546
Range on HMM: 1-150/150
Sequence Identity: 20% (34 aa)

NEVLVVDDN----QFNLLVMI------KLLQSYSII--------ADQAFDGQ-------KALDLVIQKS-------KNACCSHYRLILMDIDMP------
  .|.|||.    . .. ..       .||..  .         .|.| ||.        ||.|. ...        .   ... ||.||| ||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IMNGYQSTQAILDFYKQKHPNVNPPIISACTAFVSNEDKAQAKKRGMKFFIGKPIQIFHLDFVL
  |.|.. ...|               | ..||. . ||. .| . |.  .| ||... .|  ..
GGMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 30008.AA Response_reg 1423-1547 27 2e-13 50.67 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1423-1547
Range on HMM: 1-115/115
Sequence Identity: 27% (35 aa)

VLVVDDNQFNLLVMIKLLQ-SYSI-IADQAFDGQKALDLVIQKSKNACCSHYRLILMDIDMPIMNGYQSTQAI-LDFYKQKHPNVNPPIISACTAFVSNE
||.|||.. .. .. ..|. .. . ... | ||. ||... |. .      . ||.|||.|| |.|.. .. |    . . .    .||| .|||. . .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHH------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPII-MCTAHGDED

DKAQAKKRGMKFFIGKPIQIFHLDFVLE
|. .| . |.  .| ||. .  |   ..
DAVEALQAGANDYITKPFDPDELHAAIR